Anig017861.1
Basic Information
- Insect
- Aporophyla nigra
- Gene Symbol
- Prdm14
- Assembly
- GCA_947507805.1
- Location
- OX382321.1:5874602-5888782[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.038 3.2 9.0 2.8 3 23 217 238 204 238 0.92 2 10 0.05 4.2 8.6 0.1 3 23 261 282 259 282 0.95 3 10 0.0018 0.16 13.1 0.4 2 23 305 326 304 326 0.96 4 10 0.00027 0.023 15.7 0.3 1 23 330 352 330 352 0.98 5 10 0.0001 0.0087 17.1 0.1 1 23 357 380 357 380 0.94 6 10 7.6 6.4e+02 1.8 0.1 2 20 387 405 386 409 0.74 7 10 0.00016 0.014 16.5 1.3 1 23 416 439 416 439 0.97 8 10 0.029 2.5 9.4 3.1 1 23 445 467 445 467 0.93 9 10 4.1e-06 0.00035 21.5 3.6 1 23 473 495 473 495 0.99 10 10 1.8e-05 0.0015 19.5 3.6 1 23 501 524 501 524 0.98
Sequence Information
- Coding Sequence
- ATGGAAGAGGATCCCGACGACTTACCTCTAATGTATCACGGCAAACAAAAGAAGGAAGCAACTAGTACAGAAATAGAGTTAGATGAGATAGAGCCAGTCAAACTGGAACAAGAAATACCTAAGCCGACGGTGGCGCCCCCGCCAATGCCCAAACCAAACCGCGAGTTAGTTAAGAAAGCCACCTCTAACAATATGCCCAATGCACGTACCGGAAACCATGCTCGCAGCAGGATTGTTCTTCTTAAAGAACAAGGGTACACGGTCACCGATATAGCCACGGAACTGGGAATTTCGCGTAATACAGTTTACATGTGGCTTCAACGGTGGGCCGATTCAGGAAATCTAAACAAATTGAAAGGGACCGGCAGACCGAGAAAAACGTCTCTGGAACAAGATGCAAAGATCATTACAAGTTTAAGCGGAAAGAGTTCTGTATCAGTTCGTGCTCAGACACGCAAGGTGGCTGCAGCACATAATGTTTCTGCCGTTACTGTGAGGAGACGAATTCGTGAAGTAGAACTCCCGATGTCAAAAGTCCAACAACTGATGCGAGAAAGAGACTCAACATACATGACAGAGACGAACATACTAACAATAATAGAATATTCCTTCGTGTGCCCCTTCAAATGTAGACACAACCATCTCTTATGTTATTACTGTGGCGAGCTATACTCAGACCCCGCGTTACTAAGACACCATACAACGGAGATGCATCACCCGAAGAAATTCAAAGTGACTGAGCACAAGAAAATGGTGAAAATCGATTTGACAAGAATCGATTGTCGATTATGTGGTGTCAAAATCAATGATTTAGAAGAATTCAAGAGACATATATCCAGTATTCATAAGAAGAAGTATTATTTTAATTATAAAGATTTGGTGTTGCCGTTCCGTTTGACGAGGGATGAACTGAAATGTGCCATTTGTGATGTGCTGTTCCCTTATTTTCATGCTTTGAATAAACATATGAATGAGCATTTTAGTAATTATGTTTGTGAGACTTGTGGATTGGGTTTCGTAGACAAAGGCCGTTTCATGATGCATCAGCAACGCCACGAAGAAGGGGACTTCCCCTGTCCGGACTGTGGCAAAGTGTTCAAGGCGCAATACAATAGGGACCTCCATATAGACCGCGTACATCGGAAGATGGGCCGTGTTTACTGTCCCAAGTGTGACGTAAAACTCATGTCCTACCCGCAGAAGTTGAAGCATTTAGTCGAGGTACACGGTGAAGAGCCTCTAAGTTTCCCCTGTACGATGTGCGAGCGAATATTTGACAAAAGAAGAACGCTCACTATTCATAGACGGAAGGACCATTTAAAAGATTTCAGGTACGAATGCCAATGTTGCGGACAGAAGTTCTTCACACGTTTCGCTTTAAACAACCACATGCCGACTCATACAGGCGAACGTAACTTTAAATGTAAAGTTTGCGAGAAATGCTATCCCAGACTGAAGACCTTGAAAGACCATATGAGAATACACACAAATGATCGCAGATACCGGTGTCATGTTTGTGGACAGGCCTTTATACAGAACTGTAGCTTAAAAGGGCATATGAAGAGCCAGCATTCCGAGTATGAGATGAGAATATAA
- Protein Sequence
- MEEDPDDLPLMYHGKQKKEATSTEIELDEIEPVKLEQEIPKPTVAPPPMPKPNRELVKKATSNNMPNARTGNHARSRIVLLKEQGYTVTDIATELGISRNTVYMWLQRWADSGNLNKLKGTGRPRKTSLEQDAKIITSLSGKSSVSVRAQTRKVAAAHNVSAVTVRRRIREVELPMSKVQQLMRERDSTYMTETNILTIIEYSFVCPFKCRHNHLLCYYCGELYSDPALLRHHTTEMHHPKKFKVTEHKKMVKIDLTRIDCRLCGVKINDLEEFKRHISSIHKKKYYFNYKDLVLPFRLTRDELKCAICDVLFPYFHALNKHMNEHFSNYVCETCGLGFVDKGRFMMHQQRHEEGDFPCPDCGKVFKAQYNRDLHIDRVHRKMGRVYCPKCDVKLMSYPQKLKHLVEVHGEEPLSFPCTMCERIFDKRRTLTIHRRKDHLKDFRYECQCCGQKFFTRFALNNHMPTHTGERNFKCKVCEKCYPRLKTLKDHMRIHTNDRRYRCHVCGQAFIQNCSLKGHMKSQHSEYEMRI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00449557;
- 90% Identity
- iTF_00449557;
- 80% Identity
- -