Basic Information

Insect: Aporophyla nigra
Gene Symbol: ZFX
Assembly: GCA_947507805.1
Location: OX382319.1:10978472-11020148[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6.7e-05 0.0057 17.7 3.8 1 23 17 39 17 39 0.98

2 16 0.012 0.98 10.6 5.6 1 23 45 68 45 68 0.97

3 16 0.00033 0.028 15.5 8.8 1 23 74 96 74 96 0.98

4 16 9.6e-05 0.0081 17.2 0.5 1 23 102 124 102 124 0.97

5 16 0.00011 0.0089 17.0 2.8 1 23 130 152 130 152 0.98

6 16 4e-05 0.0034 18.4 0.8 1 22 159 180 159 182 0.90

7 16 1.8e-05 0.0015 19.5 1.2 1 23 190 213 190 213 0.98

8 16 0.0082 0.7 11.1 0.4 2 23 220 240 219 240 0.97

9 16 0.00042 0.036 15.2 0.7 1 23 246 270 246 270 0.91

10 16 0.0032 0.27 12.4 1.0 3 21 278 296 276 297 0.93

11 16 0.013 1.1 10.5 0.1 2 23 302 324 301 324 0.94

12 16 0.34 28 6.0 0.2 1 23 333 356 333 356 0.92

13 16 0.3 25 6.2 4.0 2 23 363 384 362 385 0.95

14 16 0.18 15 6.9 6.7 1 23 715 737 715 737 0.91

15 16 7.5 6.3e+02 1.8 0.3 2 13 748 757 747 768 0.70

16 16 0.04 3.3 8.9 1.3 1 23 894 916 894 916 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6.7e-05	0.0057	17.7	3.8	1	23	17	39	17	39	0.98
2	16	0.012	0.98	10.6	5.6	1	23	45	68	45	68	0.97
3	16	0.00033	0.028	15.5	8.8	1	23	74	96	74	96	0.98
4	16	9.6e-05	0.0081	17.2	0.5	1	23	102	124	102	124	0.97
5	16	0.00011	0.0089	17.0	2.8	1	23	130	152	130	152	0.98
6	16	4e-05	0.0034	18.4	0.8	1	22	159	180	159	182	0.90
7	16	1.8e-05	0.0015	19.5	1.2	1	23	190	213	190	213	0.98
8	16	0.0082	0.7	11.1	0.4	2	23	220	240	219	240	0.97
9	16	0.00042	0.036	15.2	0.7	1	23	246	270	246	270	0.91
10	16	0.0032	0.27	12.4	1.0	3	21	278	296	276	297	0.93
11	16	0.013	1.1	10.5	0.1	2	23	302	324	301	324	0.94
12	16	0.34	28	6.0	0.2	1	23	333	356	333	356	0.92
13	16	0.3	25	6.2	4.0	2	23	363	384	362	385	0.95
14	16	0.18	15	6.9	6.7	1	23	715	737	715	737	0.91
15	16	7.5	6.3e+02	1.8	0.3	2	13	748	757	747	768	0.70
16	16	0.04	3.3	8.9	1.3	1	23	894	916	894	916	0.98

Sequence Information

Coding Sequence: ATGAAGGAGAAAGCTAAAAAGAAAGGGTCGAAACAACAACAATTTGTTTATTCATGTCCACATTGTCAAAAGCATTTTGAGAACTCTTCGAATTGGCTCAACCATGTAAAACTCCATACGAATGAACTACCGTTCCAATGTGAGTTCTGTGACTACAAATGTAAAGTCCAGAAGTATTTATCTCGTCATGTGAAGAAGACACACACCAAGCCGACCGGTCATCAGTGTCCTGTGTGTGGGAAATGCTTCCATTTTGATTGTAACCTCCGTAATCACATGAGAGTGCATACTGGCGAGAAGCCGTACAAATGCAATGTTTGTGACAAGGCGTTCAACTCTCGGTACTCTTTGGGAGGACACAAGCTGATACATACTGGAGAGAAACCATATCAATGTCAGTACTGTGACTACGCTTGCCGGGATAACTCGACGATCAGACGACACATAGAGAGGCATCTAGGAATATCCAAGGACTATCCTTGTTCTATTTGTAACAAAAACTTCAAACAGAAGAAGACTTTAAGAATGCACGTGGACGATGTACACCTGGAGCTGGACACCAGGAAATATCCATGTGAGCAGTGTAATAAGTCATTTCAATCTAAAGTGAAACTCAGAACACATGTTAAAACAGTCCACAATGAGTTAAATCGTATAAAGTGCGAGATCTGCGGCCGTCTGTCTACTAAGAACAATATACAGGCGCATATGAGACGACATATTGACGTGAAACCGTATAAATGCAGCTACAAGCCTTGTGGGAAGAGGTTCAAAAATCAGGGTGACGTAAAACGCCATCTTATAATACACTACCCAGAGAAGCAACACTTATGTACCGGCTGCAACAGACGCTTCGCCCGCAAGGTCAGGCTGGACAAACACATACGAAATGGATGCCGAGTGCAGTGTTATTATTGTGGGCAGCTGTTTTCAGCCAAAATCTACCTAGCTCAACACATAAAGGATGCTCACGGACCCTACCCCAAGGCAAGAGAGTATCTGTGTGACATCTGTGATATGGTCACCTACAGTAGAAGAGGTATCATACAGCATTTAAAATTTGGACATGGCACTGAGAAAGACACAAAATGTCAAATATGCAGAAAGGATTATTTTAAATACCAAATGTTGAAGGAACATTATTTAAGTCATCATAATCTTCAATACACATTATTGGATAACAAGGTTAAAAAGAAGAAAGTTCAAGTTGCAATAAAAGAGGAACCTATCGAAGAAATTGAAGAGGTCAAAGATATCGAAGAGATGGTTGACCAGCCAGAATTTATGTATGAAGTGGAAATCCAGAAACATGACAATGATGATACTTCACCAGCCCCACCACTTTTTACCCTAAAGCCGACTCCCCCCGAACCCATAGCCATAGAGTTTCTACAGCCGAGTAGTCCCGAACAGTTTTCTGAAGACACCGACACCATAACTTACTCAAAGAAAGTGCTATCAGAGGATATATCTCGAAATCTGATAGAACGTGGCAGTACCGCAGACGAGTTCGATGACTTCTTCATTGGACATGTGCTGAACAAGCCTGAGAAGACGATTGAACTGCCGAAACAAATCGTAGACGAAGAGAAGAAAAAGCGCGTTGAAAAGCGTTTAGAGCAACTCCTGGTCAAGGCAAGAGTACGCAATCAATGGGTTGTTCTGGAGAAGTTACGGAGACAGTACAACCGACGTATCAAGACGGCTAACAGCGGGGGGGATAAAAAAGATCAAAAATCGATTAGATACTTCAAAAAACCAGAAAATGGTAAAGAATCTACAAAATTACAAAAAGTTGCCCATAATGATAAGGAACCCGATGATGATGATGAAATAAATAAAGAAGAAATTGATGATGTTGACGAACCAAACATTGAATTAGAAAATAGAAATAGTGAAAAGATTCATGTAAATGATGAAAACGCTGAAAAAAATGGTGATGAACTGATAAATGGTGAGGAAATTGCTGAAAAAAATGGTGATGAAGTGATAAATGGTGAAGAAATTGCTGACAAAAATGATGATGATGAAATGAATGATGAACCAATAGATGATAAAAAAGATCTCGATTACAAAGACAGTGATTTAGAAAGTAATAGTGATGAAGATTCTAATCCTAATGGAAAACTAACATTCAATACGCATCAATGTTATATTTGTTTCAAGCTCTTCAAAACGAAGACAGACTTAAAAGTCCACTGCAAGGAACATTTCGATATATGTAACGAAAAAATGCTTAAAAAGTGTCCTTTTTGTGGCTACGTTACCAACTTAACAATACGAAGACATATTCAACTCGTTCATAATGTAACTCTCGATATACCGTACGGGCGAATCAAAGAGCGGGACACACAGAACGGGTCCAAATACGTCTTCGAAATCGATAAAGACTGTGACCTAGAAGTCATACCAAGTATTAGCAATTTAAACAAAATAGCTTCCATGAAAATAGATGAGAAAAATCGAGAATCGAAAAACGTATTCGTGGGAACGACGAAGTTGGTTAAAAAGGGGGGAGACTGGATGGTAGAAAAGCAGAAAGTCAATATCAATAATGATTACTTGCTACCAGAATTTTATGAGGAAGATTATCAAGCTTTGAAATCTATAGGAGATACTTACTTAGAACAAATTAGAAGTTTGAGTATTATTGCTAAGAAAAAAGGATTAAAAATTCTTTATCCCTGCCAAGGGTGTGACAAAATCTGTCTAACAATGAGCGCTTTAAAACTGCATAATAGAAAACACGAAGCTAACCCAAAGAGATTTAAACCTAAAGTGTGGAAGAATAAGATTTTAATTGGCATAGGGGGTAGATATAGTCATGTTAACAAGAAAAATAACAGAAAAAAATACGGGAATAAGAAACAAAACAATAATAGCGATGTTACGAATCAGAATGACGGTGAAAGCAGTCCCAAAAAATACCGTAGATTAGAAAGAATCGGTAAAAAAGAAAAACAAACTGAGCCTGTAGCACATCGTTTTGCCGATCCGAGCCCTGTCAAAAATAACCATAAATGCGATAGAGAACTGATAGAATTCTATCAAAAGAACATCAAGGGAGGCGACATAGAATTTTGGCAATTTTTGAAGATTTTCAACAAAATGAGTCGCGAAAAAATCAACGATTTCAAAGACTTGGAAAATCGATTCGACTTTGGTATGCATAATATCATCAGGTATGATGAAAATACAACAGAATCGAATAAAGAAGATACAGAAGAGGATATCCAGGTATTACCTAAAAAGAGGATAAGAAAGAAGAAAGCGTTTACTAGAGTCATTAGGATAAGTAAAAAAGAGTATCTAAGAAGACTTGCGATTAAAAACCAAATGAGACAAAGGTTAGAGCAGTCGAAAACTTAA
Protein Sequence: MKEKAKKKGSKQQQFVYSCPHCQKHFENSSNWLNHVKLHTNELPFQCEFCDYKCKVQKYLSRHVKKTHTKPTGHQCPVCGKCFHFDCNLRNHMRVHTGEKPYKCNVCDKAFNSRYSLGGHKLIHTGEKPYQCQYCDYACRDNSTIRRHIERHLGISKDYPCSICNKNFKQKKTLRMHVDDVHLELDTRKYPCEQCNKSFQSKVKLRTHVKTVHNELNRIKCEICGRLSTKNNIQAHMRRHIDVKPYKCSYKPCGKRFKNQGDVKRHLIIHYPEKQHLCTGCNRRFARKVRLDKHIRNGCRVQCYYCGQLFSAKIYLAQHIKDAHGPYPKAREYLCDICDMVTYSRRGIIQHLKFGHGTEKDTKCQICRKDYFKYQMLKEHYLSHHNLQYTLLDNKVKKKKVQVAIKEEPIEEIEEVKDIEEMVDQPEFMYEVEIQKHDNDDTSPAPPLFTLKPTPPEPIAIEFLQPSSPEQFSEDTDTITYSKKVLSEDISRNLIERGSTADEFDDFFIGHVLNKPEKTIELPKQIVDEEKKKRVEKRLEQLLVKARVRNQWVVLEKLRRQYNRRIKTANSGGDKKDQKSIRYFKKPENGKESTKLQKVAHNDKEPDDDDEINKEEIDDVDEPNIELENRNSEKIHVNDENAEKNGDELINGEEIAEKNGDEVINGEEIADKNDDDEMNDEPIDDKKDLDYKDSDLESNSDEDSNPNGKLTFNTHQCYICFKLFKTKTDLKVHCKEHFDICNEKMLKKCPFCGYVTNLTIRRHIQLVHNVTLDIPYGRIKERDTQNGSKYVFEIDKDCDLEVIPSISNLNKIASMKIDEKNRESKNVFVGTTKLVKKGGDWMVEKQKVNINNDYLLPEFYEEDYQALKSIGDTYLEQIRSLSIIAKKKGLKILYPCQGCDKICLTMSALKLHNRKHEANPKRFKPKVWKNKILIGIGGRYSHVNKKNNRKKYGNKKQNNNSDVTNQNDGESSPKKYRRLERIGKKEKQTEPVAHRFADPSPVKNNHKCDRELIEFYQKNIKGGDIEFWQFLKIFNKMSREKINDFKDLENRFDFGMHNIIRYDENTTESNKEDTEEDIQVLPKKRIRKKKAFTRVIRISKKEYLRRLAIKNQMRQRLEQSKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -