Basic Information

Insect: Aporophyla nigra
Gene Symbol: ZNF296
Assembly: GCA_947507805.1
Location: OX382321.1:12914435-12933440[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.41 35 5.7 0.2 3 23 122 142 120 142 0.96

2 15 0.0019 0.16 13.1 2.8 1 23 287 309 287 309 0.99

3 15 3e-05 0.0025 18.8 0.4 1 23 315 338 315 338 0.97

4 15 0.0038 0.32 12.2 1.6 1 23 343 366 343 366 0.94

5 15 8e-05 0.0067 17.4 0.9 3 23 543 563 542 563 0.98

6 15 0.00014 0.011 16.7 3.6 1 23 569 591 569 591 0.98

7 15 0.55 46 5.4 5.0 1 23 657 679 650 679 0.97

8 15 3.3 2.8e+02 2.9 0.1 2 23 687 708 686 708 0.89

9 15 0.0013 0.11 13.6 2.3 1 23 714 736 714 736 0.96

10 15 0.0034 0.29 12.3 3.0 1 23 742 764 742 764 0.98

11 15 0.28 24 6.3 7.2 1 23 773 795 773 795 0.98

12 15 0.00012 0.01 16.9 0.3 2 23 853 874 853 874 0.96

13 15 0.007 0.59 11.3 3.8 1 23 891 913 891 913 0.96

14 15 1.7e-06 0.00014 22.7 0.7 1 23 919 941 919 941 0.98

15 15 5.7e-07 4.8e-05 24.2 3.1 1 23 947 970 947 970 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.41	35	5.7	0.2	3	23	122	142	120	142	0.96
2	15	0.0019	0.16	13.1	2.8	1	23	287	309	287	309	0.99
3	15	3e-05	0.0025	18.8	0.4	1	23	315	338	315	338	0.97
4	15	0.0038	0.32	12.2	1.6	1	23	343	366	343	366	0.94
5	15	8e-05	0.0067	17.4	0.9	3	23	543	563	542	563	0.98
6	15	0.00014	0.011	16.7	3.6	1	23	569	591	569	591	0.98
7	15	0.55	46	5.4	5.0	1	23	657	679	650	679	0.97
8	15	3.3	2.8e+02	2.9	0.1	2	23	687	708	686	708	0.89
9	15	0.0013	0.11	13.6	2.3	1	23	714	736	714	736	0.96
10	15	0.0034	0.29	12.3	3.0	1	23	742	764	742	764	0.98
11	15	0.28	24	6.3	7.2	1	23	773	795	773	795	0.98
12	15	0.00012	0.01	16.9	0.3	2	23	853	874	853	874	0.96
13	15	0.007	0.59	11.3	3.8	1	23	891	913	891	913	0.96
14	15	1.7e-06	0.00014	22.7	0.7	1	23	919	941	919	941	0.98
15	15	5.7e-07	4.8e-05	24.2	3.1	1	23	947	970	947	970	0.98

Sequence Information

Coding Sequence: ATGAACCACACAGCAGCTGCAATACCAGGAAACATGGATGTTGACCCGCTGAGTTCGTATGAGTACCCAGCGTACGACAGCTATGCCGCCCAGTCCTACTCGTACCCCAGCAAGCTACAGCAGTCCATATACCAAGCGTATCAACAAACTAACACCAACTACAATAATACACAACCAGCACAACTACAAGAACCATTCAACAATCCACCACCAACACAAGCAACCGTTGATATTGAAGTACCACCTAAAAATGAAAATATTGACTCAAAACCAGTACTTAAAAAGAGAAAGAAGGAGAAGAATGGCCAGAAGAGTACTTATTGTTCTGAGAAGATAACAGATGCTGCGTTCAAGTTCTACGGTTGTTCCGTCTGTAACATCAGTTACAATGCGTTGCATGACCTGGACCAGCACGTGACCGTTCACAAGAACAGAATGACAAGTTATAGACTGAGGTTAAGAAATCAATTTAAAAAGAAACAAATGAAAAAAGAAAAGAAAAGATTAAATAAAAAGATGGTTAAAATTAAAAAAGAAATTGAGTTTGATATTGAAATTAAGCCTGAAGACGGTTATATCGGTGAAGAGAAAGCAACGGATGTTATTACTAACGGAATCAATCCAAATTCTGAATGTAATAGAAATGTAGATAGTGGAACCAGTGCAATAGAAGCCCAAAATAGTCAAATGAATAACAATAATGCCACAAATTCTGTTAATAATGAACCGCAGATTAAAGAAACGAATTTAAGTAACGGGAAAGTGGATAAGGAAAATAGTGAAAACGGAAATAGTGTAAATAATAAAGATAAGGAGAACAGTATAGATGAAGCAGAGTTAAATAATCTAGAGAAAATTTACAAATGTTTTGCTTGTCAGAAGCAGTTTACGTTGAGTTATTATTTAAAACTACATGTGAGATCGCACACAGACGAGAAGCCGTACACGTGCAGTGTGTGTGGCCAGTCGTTCATCACGGCGAGCAAGCTGGGCCGACACAACAAGCGCATCCACCTCGCCGAACGCTACCAGTGCCGCATCTGCTTCAAGATATACTCCCGGTTCGAGCTGCTGACGGCTCACTTCGACAAGACGCATCCTGAAGACAAGCTGGAGGGAGAGCCGTATGACTACAACGCGATCCTCCCGTACCTGAAGGAGTTAGAGGAACAGCTCCTCGCTCCTGAGCTACTGGAGCTGGACAACAAGCCCAAGTCTGAGGATCTGTATTGGGAGCAGCAGGTGGGTCCGCACCAGCATCCCGTGCCTGGTGCGCCGGTGCCACAGGACATCAAAGAGGAGGCACAAGACGAGGACCAAAAAGAACTGGTGCCGAAGCTAGACATACTTATAGAGGAGGTTAAGGTAGACTTTGACGTCGCGGTCAAGCACGAGCTGCCCGACGATCAGCCGGTAGACGCTCCGGAAGACGTAGGTGACGCGACGGAGGACGCGCCGGGTGATGGGATGGATGACGGGTTGGATGACGGGATGGATGACGGGACGGATATCAAGGATGAAGATAGTCAGTCCGACGAGGACTACTTCCCGTCCAACACGTGGGCGCGCGCACACGCGCCCCCCCCGCGCGCCTCGCCGCCGCCCGCGCGGCGCGGCGCGCGCGCCTGCGGCGTGTGCCACAAGAGCATCAGCACGGCGTCGTACATGCGTGTACACATGCGCACCCACACGGGAGAGAGGCCCTTCAAGTGCTACAAGTGTGGGCGAGGGTTTATCACCAGCAGCAAGATGCACCGTCACGTGCTCACGCATGCGCAAGACAAAGACGACGTCAAGGCGGAAGGAGAAGACACCAAACTGGACGTGGACGATAACGCCGTGGACGAGGACCAACAGCAAGAAGAGGGCGCTAAAAAACCAGCGAAGAAAAAATCCAAAATGAAATTGAAATCGTCAAAACTGAAGAGTGGCGACGAGAAGCCGCGCCGCAAGCATCAGAAGAGACCGCACGCCTGCGAGTACTGCAACCAGAAATTCCTCCACCTGAACATGCTGGAGGTTCATAGACAGTCGCACGCGGGCGAAGCCCTGGTGCTGCGCTGCCACTACTGCCTGCAGGAGGCGCCCAGCGACGACGCGCTGCGGGCGCACGAGGCGGAGCACCAGGGGGCCAAGCCCTACCTCTGCACCGTGTGTGGGAAGACCTACAAAAAGAGGGAGACTATGGTATACCACCGCAAGCGCCACGCGTCCGACAAGGAGTTCGTGTGCGACGTGTGCTCCAAGCGCTTCCCGGCGGCCTGCAAGCTGCACAAGCACCTGCTGACGCACAGCCGCGACGCCTACGTGCTGCGCTACGAGTGTCCCGTGTGCGCGCACATGTTCCACACGCGCTACCACGTGCACATGCACCTCAGCACGCACCAGAAGGAGGGCCTGATCTTAGAAGAGAACCGCAGCGAGATCCTGGCGATGGTCCTACAGAACGCGCGCAAGATCCCTCGCGCAGGAGCCACCAGCGGGACACACCCACGTGAAGCGCACGCACAAGACACACACGACACACACACACTACCTCCTGACGAGAGGTCTCGCGTGTGTAACATATGCGGCGCCGTATTCTCGCACTTCTACTACTTAGAGGAGCATCTCAAGGGCCACGGAGAGCGTATCGCCGTCGCCGACCTCGACAAGCCAGAAGACAAGAAGTACATCTGTCAGATTTGCAATAAGGGCTTCAAGCTGCACTACTACCTGAAACTGCACAGCTTTACGCACTCCAAGGAGAAACCCTTCATCTGCCAGCAGTGCGGGAAAGGGTTCATCACGAAAGGTAAGCTCAAGAGGCACCTGGAGACTCACACGGGCCTGAAGAAGTACCAGTGCCACATCTGCTACAAGTTCTTCACTCGGCCCAGCTATCTACGGATCCACGTACGAACCATCCACGGCACACAGGACTACAATTTCAGGTTCGACAAGGGCTACGGTGTTGGTTCCCTGGCTGTCTCAGCCATGGCCATGTCGGATGCCAGTCAGAATAGTATTTAA
Protein Sequence: MNHTAAAIPGNMDVDPLSSYEYPAYDSYAAQSYSYPSKLQQSIYQAYQQTNTNYNNTQPAQLQEPFNNPPPTQATVDIEVPPKNENIDSKPVLKKRKKEKNGQKSTYCSEKITDAAFKFYGCSVCNISYNALHDLDQHVTVHKNRMTSYRLRLRNQFKKKQMKKEKKRLNKKMVKIKKEIEFDIEIKPEDGYIGEEKATDVITNGINPNSECNRNVDSGTSAIEAQNSQMNNNNATNSVNNEPQIKETNLSNGKVDKENSENGNSVNNKDKENSIDEAELNNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCSVCGQSFITASKLGRHNKRIHLAERYQCRICFKIYSRFELLTAHFDKTHPEDKLEGEPYDYNAILPYLKELEEQLLAPELLELDNKPKSEDLYWEQQVGPHQHPVPGAPVPQDIKEEAQDEDQKELVPKLDILIEEVKVDFDVAVKHELPDDQPVDAPEDVGDATEDAPGDGMDDGLDDGMDDGTDIKDEDSQSDEDYFPSNTWARAHAPPPRASPPPARRGARACGVCHKSISTASYMRVHMRTHTGERPFKCYKCGRGFITSSKMHRHVLTHAQDKDDVKAEGEDTKLDVDDNAVDEDQQQEEGAKKPAKKKSKMKLKSSKLKSGDEKPRRKHQKRPHACEYCNQKFLHLNMLEVHRQSHAGEALVLRCHYCLQEAPSDDALRAHEAEHQGAKPYLCTVCGKTYKKRETMVYHRKRHASDKEFVCDVCSKRFPAACKLHKHLLTHSRDAYVLRYECPVCAHMFHTRYHVHMHLSTHQKEGLILEENRSEILAMVLQNARKIPRAGATSGTHPREAHAQDTHDTHTLPPDERSRVCNICGAVFSHFYYLEEHLKGHGERIAVADLDKPEDKKYICQICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRFDKGYGVGSLAVSAMAMSDASQNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00121693;
90% Identity: -
80% Identity: -