Basic Information

Insect: Apolygus lucorum
Gene Symbol: Dox-A2
Assembly: GCA_009739505.2
Location: CM019176.2:23418505-23463992[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.072 5.9 7.7 1.4 1 23 757 779 757 779 0.96

2 12 0.0014 0.12 13.1 0.2 2 19 785 802 784 808 0.93

3 12 4.8e-05 0.004 17.6 0.7 2 23 841 863 840 863 0.95

4 12 0.0062 0.51 11.0 0.9 1 23 870 893 870 893 0.96

5 12 0.0097 0.81 10.4 7.2 1 23 899 921 899 921 0.97

6 12 7.4e-07 6.1e-05 23.4 1.0 2 23 943 964 942 964 0.96

7 12 0.0046 0.38 11.4 4.0 1 23 969 991 969 991 0.97

8 12 2.3e-07 1.9e-05 25.0 2.1 1 23 997 1019 997 1019 0.99

9 12 3.7e-05 0.003 18.0 1.3 1 23 1025 1047 1025 1047 0.99

10 12 0.00029 0.024 15.2 2.9 1 23 1053 1075 1053 1075 0.98

11 12 8.7e-06 0.00072 20.0 1.2 1 23 1081 1103 1081 1103 0.99

12 12 3e-08 2.5e-06 27.7 0.6 1 23 1109 1131 1109 1131 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.072	5.9	7.7	1.4	1	23	757	779	757	779	0.96
2	12	0.0014	0.12	13.1	0.2	2	19	785	802	784	808	0.93
3	12	4.8e-05	0.004	17.6	0.7	2	23	841	863	840	863	0.95
4	12	0.0062	0.51	11.0	0.9	1	23	870	893	870	893	0.96
5	12	0.0097	0.81	10.4	7.2	1	23	899	921	899	921	0.97
6	12	7.4e-07	6.1e-05	23.4	1.0	2	23	943	964	942	964	0.96
7	12	0.0046	0.38	11.4	4.0	1	23	969	991	969	991	0.97
8	12	2.3e-07	1.9e-05	25.0	2.1	1	23	997	1019	997	1019	0.99
9	12	3.7e-05	0.003	18.0	1.3	1	23	1025	1047	1025	1047	0.99
10	12	0.00029	0.024	15.2	2.9	1	23	1053	1075	1053	1075	0.98
11	12	8.7e-06	0.00072	20.0	1.2	1	23	1081	1103	1081	1103	0.99
12	12	3e-08	2.5e-06	27.7	0.6	1	23	1109	1131	1109	1131	0.98

Sequence Information

Coding Sequence: ATGCAGCTCCGACGTTCTCGATGGATcttagaattaAATCTACCTAATACTTTTTCTATCTATCGATTCATTATTTCAACCAAAACGTTTAGCAATGTGGACAGTCCAGCGGCTGAACCTGAAGTGTCGGTCGATACAACAAGCATTCAAGAAATACGAGAAAACATCAGGCAGATTGAGAAAGCCGTGCAAAGCAAAGAGCCCCGATTCATCCTTAGGGTTCTCAGGTTATTGCCAGTTACGAGGAGAAAATGCAATCCCACGGTACTCCGAGGTATCATTACTGGGTTCTATACTCATTCGACAACCGAAAGGGACGCTCTGATGGCTTTCGTGGACGAGCCAATGGAAACCGACACTGTCACCGAGAAGCAGAGGATGCGGTCTACCAAGAGCTCTGCAAACCCGTTGCTCCCTGAGGTCGACGCTTACCTCCACCTCCTCATCCTCGTCAAGCTCATTGATGCCAATAAATACGAGGATGCCGTTAAGTGTTCGGACGCCCTCATGACCAAAGTGGTCGCTCAAAATAGGAGAACTTCGGATCTCATTGCAGCCAAGTGCTACTTCTATCATTCGCGAGCTTATGAACTTACAAACAAGCTTGATGCCATCAGAGGGTTCCTTCATTCACGCCTCCGCACAGCAACTCTCCGCAATGACTTCGAAGGCCAGGCGGTGTTGATTAACTGTTTACTACGGAACTACCTGCATTACAACCTCTATGATCAAGCTGATAAACTAGTATCAAAATCAGTATACCCAGAATCAGCTAGCAACAACGAATGGGCTAGATTCCTTTACTATCTAGGACGCATAAAGGCTGCACGTTTAGAATATTCAGAAGCCCACAAGCACCTTGTGCAGGCCCTCCGTAAAGCTCCTCAGCATGCTGCTGTAGGATTCAGGCAGACCGTTCAGAAACTCGCTGTTACAGTTGAACTTCTTTTGGGTGACATTCCTGACCGCCAGATCTTCAGGCAAGCCCCTCTTCGTCGGTCTCTGGCACCCTACCTTCAGCTCACCCAAGCTGTTCGCACAGGAAACCTGAAAAGGTTCAATGAAGTTCTGGAAATGTTCGGCGCTCAATTCCGTTCGGATCACACATTCACGCTGATTTTAAGGCTTCGCCACAATGTCATCAAAACGGCCATCAGGTGCATTGGACTGTCATACTCCAGGATTTCTTTACAAGACGTGGCCAAGAAGTTGGGACTCGACTCACCCTTAGATGCTGAATTCATCGTCGCAAAGGCAATCAGGGATGGTGTTATTGAGGCCACAATTGATCCAGAACACGGATACATGTCCAGCAAAGAAGTCATGGATATCTACTGCACGCGTGAACCACAATTGGCCTTCCATCAAAGGATAGCCTTCTGTCTGGAGCTCCACAATCAGAGTGTGAAAGCCATGCGCTACCCTCCCAAATCTTATGGCAAAGAGCTGGAATCTGCTGAAGAGCGACGGGAGCGTGAGCAGCAAGATCTTGAGCTCGCCAAAGAAATGGCTGATGAGGATGATGATCCTAGTATCAACGGTATAAGTTTGAGTGCGATTAGTGAAGAAGGAATACCCAACTACGAGCTAATCAATAAATACCTGCCTTTCAGAGTCGAAGACGATGGAAAATTACCCCAAACTTTATGCAGCGGGTGCCACATTCATTTACGGAATACAGTGAGCTTTCTAGAGCTAATCATCAAAGGACAGGCGCTTCTTCAGAAATTGTATAAACATATCCTCTCCAAAGAACAGATTGGTGGGGATTCTACTAATAATTCGAATTCTCACTTTTTCAATGATAATAACGAGAAACTCTACCATGACAGTCATAGCATCCGAGCTCAAGTGGATGTTGCTGGAGTTCAACCCCCAAAAAGGAAACGTGGGAGGCCTCGAAAAGATGAGGTTAAGGCCTCCACAAATACTCCTGAAGGTTATGGCACTCCGGTAGTTGAAACGCACCCTGTAGCTCAACCGTTAGAGCCTATTGATGAGAGAGATGAAGAAGAATTGCCACCAGACGGCAAGCGTAGAAGGAAAAAACCACTTAGGTATTTGGAATCCATTCAAGGAAAAGAGCTGGAAAAGGTTTTTCACGAAAATGGAGTAACGGACGATGGATTTCTACAGAAAGAAGATGAATTGGGAGAGTCAGGTGAAATGGAGGTGATTGGACTTGTGCAGAATAGCAATGGGGAATCTATCGGTGAATTCCTGATGTGCAGAAGATCGTCTGATTCCCAAGCGAAGAAAAAGTTTCTTTTTCGCTGTGATGTCTGCCATTCTATGTTTTCTCAGGAAAACAAATTCGTAGGGCACGTTGCTCGCCACAATGCCCCCAAGTTGAAATGTAGTCAGTGCGATGAGGTTTTTGAGACTTCTAAAGACTTGGAGAGCCATAGCATCGACTCTGGACACGACAACACCATTGATCAGCTAAATGGTGAAACGGTAGAAAACCCTGACGTGCAGCTCTTGCCTGAGGAACAGGACGCGGCACAAAAAGTAAAATCTACTTGCCCAGTTTGCCAGAAAACTTTCAAGTTCGCATTAAGCTTGAAGACTCACATGAAAGCCGAACATGACGATGTTGCTGGAGTTTTCCCTTGCGACATTTGcggcaaaaagttaaaatacATGTCTTCCATCATTCACCATAAAGAAACGGAGCATAGCAATGGAACAAAGTTCATGTGTTGCAAATGCAATATGATATTCAAGCACAGGCGATTGCTCCAAAAACATCAGTACGTTCACGGGGAGAACGGCAAGGTTGACCGACAAGGCAATCAAATTCAGAGCGAGCGTATCCCAGGTTTGAACTGTCCGGACTGTGGGAAATACTTTAAATCCAAATCGTATCTCAAGATCCATACTAGGCTCCATGGTAATAAGTTACATGTCTGCGAAATATGCAATGCATCGTACCATCATAGATCTGCGCTCATGCTCCACAGAAGGCTGCATTCGGAAGAAAAGCCGTTCCAATGTTACTTCTGCAATAAAATGTTTTCGCAAAAGGGTAATCTCAACGAACACATGCGAATACATACTGGAGAAAAACCCTTCCAGTGTGAAATATGCAATAGAATCTTCGCTACTTCATCTCAGAGGCGTCTTCATCTCAAGAGGCATATAGGAGAGAAGCCGTTTGAATGTGAAATATGCCAGAAGGCGTTCCTCCACAAAGACACCTTTTTAACGCATATGAGGCGTCACACAGGTGAACGACCGTATCAGtgcgaaaaatgtaaaaaaacgtTCACGGAGTTGTCCGCCGTTAGAAAACACGTAAGGATTCACACAGGGGAGAAACCGTTTGTGTGTACCGTTTGTGGCAAAGCCTTCGCAGACAGTTCTAATCTCACCAAACACAAAAAGACTCATTCCAAGGCGTGCGCTGATGCTAACTTACTTGTCTCAGACATACTCCCGAACGGGCTCAGTGTTAACGACCTTGCCCTTGTCGATAGCTCTGATGAGAAACAGTTCTGGGCAGTCGTGAAGCAGACGTCGGACTCTCAAGATGGCAAAGATATTGACCAACAACAAGTCATCTACATTACATACAACGACCCAGATGACCCTAATTCAAAGGTTAGCGAAGCACTCATCGTGAACAATGAAGCCGTGGTGGACAAGGGTGATCATGAGATAATAGTGGAAGAGCCTGAAGAAGAGATCGTCGCAAGCCGGGCATTGATAGCATCAACTAATGAAATCAATACAAATAGCCCCAACCTTTCGCCAACATCCTCTCAACAGGGGATACAGGGAATGACCCCTCTTGAAGGTCAAGTTGTGATGGATGAACACGGGAATCCTTTAAGGTTTACCACCGCTGATGGAGGAATTTTCCAGGTGACCACCATCGATGGAGAATCACTACAGCTCACTGGGAGCGATGGTAGCTCAATGCCAGTGAGGATAACCACTGCGGATGGCGAGACTCTAACTCCAGCAGGACTCAATATGTCATCAATGGTTGGCGATGTGGTTGAGGATTCGTTGGTATCAGCGGCTGTCGAATCGTTGGAGCTTGTGAGCACAGCAGACGTGCGACTGCTCTCAGAGGCAGCACTAGAGTTTCTCCCCCTCACGTAG
Protein Sequence: MQLRRSRWILELNLPNTFSIYRFIISTKTFSNVDSPAAEPEVSVDTTSIQEIRENIRQIEKAVQSKEPRFILRVLRLLPVTRRKCNPTVLRGIITGFYTHSTTERDALMAFVDEPMETDTVTEKQRMRSTKSSANPLLPEVDAYLHLLILVKLIDANKYEDAVKCSDALMTKVVAQNRRTSDLIAAKCYFYHSRAYELTNKLDAIRGFLHSRLRTATLRNDFEGQAVLINCLLRNYLHYNLYDQADKLVSKSVYPESASNNEWARFLYYLGRIKAARLEYSEAHKHLVQALRKAPQHAAVGFRQTVQKLAVTVELLLGDIPDRQIFRQAPLRRSLAPYLQLTQAVRTGNLKRFNEVLEMFGAQFRSDHTFTLILRLRHNVIKTAIRCIGLSYSRISLQDVAKKLGLDSPLDAEFIVAKAIRDGVIEATIDPEHGYMSSKEVMDIYCTREPQLAFHQRIAFCLELHNQSVKAMRYPPKSYGKELESAEERREREQQDLELAKEMADEDDDPSINGISLSAISEEGIPNYELINKYLPFRVEDDGKLPQTLCSGCHIHLRNTVSFLELIIKGQALLQKLYKHILSKEQIGGDSTNNSNSHFFNDNNEKLYHDSHSIRAQVDVAGVQPPKRKRGRPRKDEVKASTNTPEGYGTPVVETHPVAQPLEPIDERDEEELPPDGKRRRKKPLRYLESIQGKELEKVFHENGVTDDGFLQKEDELGESGEMEVIGLVQNSNGESIGEFLMCRRSSDSQAKKKFLFRCDVCHSMFSQENKFVGHVARHNAPKLKCSQCDEVFETSKDLESHSIDSGHDNTIDQLNGETVENPDVQLLPEEQDAAQKVKSTCPVCQKTFKFALSLKTHMKAEHDDVAGVFPCDICGKKLKYMSSIIHHKETEHSNGTKFMCCKCNMIFKHRRLLQKHQYVHGENGKVDRQGNQIQSERIPGLNCPDCGKYFKSKSYLKIHTRLHGNKLHVCEICNASYHHRSALMLHRRLHSEEKPFQCYFCNKMFSQKGNLNEHMRIHTGEKPFQCEICNRIFATSSQRRLHLKRHIGEKPFECEICQKAFLHKDTFLTHMRRHTGERPYQCEKCKKTFTELSAVRKHVRIHTGEKPFVCTVCGKAFADSSNLTKHKKTHSKACADANLLVSDILPNGLSVNDLALVDSSDEKQFWAVVKQTSDSQDGKDIDQQQVIYITYNDPDDPNSKVSEALIVNNEAVVDKGDHEIIVEEPEEEIVASRALIASTNEINTNSPNLSPTSSQQGIQGMTPLEGQVVMDEHGNPLRFTTADGGIFQVTTIDGESLQLTGSDGSSMPVRITTADGETLTPAGLNMSSMVGDVVEDSLVSAAVESLELVSTADVRLLSEAALEFLPLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -