Aluc003756.1
Basic Information
- Insect
- Apolygus lucorum
- Gene Symbol
- ZFX
- Assembly
- GCA_009739505.2
- Location
- CM019169.2:14503773-14536566[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 3.3e-06 0.00027 21.3 0.8 1 23 21 43 21 43 0.97 2 11 3.4e-06 0.00028 21.3 0.1 1 23 49 72 49 72 0.95 3 11 1.2e-05 0.001 19.5 0.7 1 23 78 100 78 100 0.99 4 11 1.8e-07 1.5e-05 25.3 1.6 1 23 106 128 106 128 0.99 5 11 0.037 3.1 8.6 4.8 1 23 134 156 134 156 0.98 6 11 1.1e-07 8.9e-06 26.0 1.9 1 23 162 185 162 185 0.94 7 11 0.00074 0.061 13.9 3.5 1 23 191 211 191 211 0.98 8 11 2.1e-06 0.00018 21.9 2.3 1 23 217 239 217 239 0.98 9 11 3.9e-05 0.0032 17.9 2.2 1 23 245 267 245 267 0.99 10 11 5.2e-05 0.0043 17.6 1.3 1 23 273 297 273 297 0.97 11 11 0.1 8.4 7.2 0.2 1 21 303 323 303 324 0.91
Sequence Information
- Coding Sequence
- atgGGATACAGAAAGACAAATCTGTTGACTGCTCCAAAAATGAAGGAGGGCGGAGCGCAGCACGTCTGCGAAGTGTGCGGAAAAGCTTTCGATGCTTCTTTCAAGTTGAAGAAACACATGAGAGCGCATACAGGAGAAAAGCCGTACACTTGCAAGGAATGCGGCCTGTCGTACTCGCAGAGCGGTGGTCTGAGGAATCACATAGTGATCGTACATCGGAACGAAAAGATCTTCCAGTGCTTTTACTGCGGCAAAGGGTTTCCCATCAAAGACAGACTCAAATTGCACCTGAGGATCCACACTGGAGAGAAACCGTACAGCTGCTCTCACTGCCCGAAGGCGTTTGCAAGAGGGAGTCAGCTCACGCAGCATCTGAGAACGCACACCAAAGACAGACCGTTCACGTGCCCGCAATGCAACAGCGACTTCGTGTGCCGCAACAACCTGCTGCATCACATCAAGCGGCACCAAGGCGAGAGGGACTACGTCTGTCACAAGTGCGGTAAGTCTTTCATCCGGAGAGACAGCCTGCAGAAGCACTTGGCTTGGTTTCACGCCAATTTGAAGGCGTTCGAGTGCAAGATCTGCAACAAGCGGTACAAGGGTCACTTGCTGCAGCACATGAGGATTCACAAGGCTGAAAAACCGCACAAGTGCTCTTGGTGTGACATGCGTTTCGTGCAGAGATCTCAACTGACGGTGCATGAGCGGACGCATTCTGGGATTCGACCCTACAGGTGTGCTGTTTGTCACATGGCGTTTGCTCATTCCACTGCTCTCAAGATGCACGTCAGGCGCCATACTGGAGAGAAACCGTTCAAATGTCTGATTTGTGACAACAAGGCGTTTTCTCAGTTACCTCATTTGAAGAAACACATGCTCTCGATTCATAAAACCAACAAGCCGTACTACTGCATCGGATGCAAATTGTTCTTCCAGACCAAAATCCAGTTGCAGGAGCACCAAGAAGTGTGTACTGCGGGAGTCAAAACTGAACAAGAAGAAGATGACCCGGTAATGCCTGTAGGTAGAATGCGTCTTCTCCTGGCGATCCTCCTCCAAAAGATATCCACCCCTGAAAAATTAGAGAAACTGGGATTCGGGAAGCGTTTGATCGACCACGTCCTCACTGACAGCATCGAGCAGTCAGGGAGAACTCCATGTCTGGACCCTCTGCTGACGGAAGCTGAACGCCTGAGGGCGAATGTCCAGATCCTCTTGGACTGGACGGTTCCTAAAGTTCACATGGACAAGTTTAAGAGCGAGAGGCGATCCATGGAGGAACTACTTGAAGAGTTCACCAACCTTTTCATTTATGAATAG
- Protein Sequence
- MGYRKTNLLTAPKMKEGGAQHVCEVCGKAFDASFKLKKHMRAHTGEKPYTCKECGLSYSQSGGLRNHIVIVHRNEKIFQCFYCGKGFPIKDRLKLHLRIHTGEKPYSCSHCPKAFARGSQLTQHLRTHTKDRPFTCPQCNSDFVCRNNLLHHIKRHQGERDYVCHKCGKSFIRRDSLQKHLAWFHANLKAFECKICNKRYKGHLLQHMRIHKAEKPHKCSWCDMRFVQRSQLTVHERTHSGIRPYRCAVCHMAFAHSTALKMHVRRHTGEKPFKCLICDNKAFSQLPHLKKHMLSIHKTNKPYYCIGCKLFFQTKIQLQEHQEVCTAGVKTEQEEDDPVMPVGRMRLLLAILLQKISTPEKLEKLGFGKRLIDHVLTDSIEQSGRTPCLDPLLTEAERLRANVQILLDWTVPKVHMDKFKSERRSMEELLEEFTNLFIYE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01500566;
- 90% Identity
- iTF_00884488;
- 80% Identity
- -