Basic Information

Gene Symbol
-
Assembly
GCA_036924255.1
Location
JAUPFN010000031.1:5930041-5936791[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00017 0.023 16.5 1.1 1 23 132 154 132 154 0.97
2 9 0.00022 0.03 16.1 2.0 1 23 161 183 161 183 0.98
3 9 7.5e-08 1e-05 27.0 1.1 1 23 189 211 189 211 0.97
4 9 0.0021 0.29 13.0 7.1 1 23 217 239 217 239 0.96
5 9 1.4e-06 0.00019 23.0 2.2 1 23 245 267 245 267 0.97
6 9 7.6e-07 0.00011 23.9 2.3 1 23 273 295 273 295 0.98
7 9 5e-06 0.00069 21.3 1.7 2 23 308 329 307 329 0.97
8 9 7.5e-06 0.001 20.7 3.0 1 21 335 355 335 357 0.95
9 9 0.15 21 7.2 4.0 5 19 366 380 355 383 0.86

Sequence Information

Coding Sequence
atgtctactaaaataaaaattaaagaagaACCAGCAGATTTCTGTGATTATTCTTCCGGACATTTATTTGAAGATGACACAATTAAagaagaaaatttttcaaacgaGGATGAGAATATcactattaaaattgaaaagGAGACTAATATGTTGAATTACGCTATTGAAGTTGAAATTGATGCTGTAAAGAAAGAAGTAGTATTTAATGAACCAGAAGAAAGCGTAAATGTCCTGATAGACAAGTCAGAAATATCGAATTTCGAATGTGataaTGAAGGGTCGTCTTCTCATACTGAAGGTGGAAATATAGCAGGTGTGAAATCAATATCTTCAGAATCACTAATTGAAGAACTTccattaaaaattgaaatacttaATGATGAAGAAAAGCCGTATAATTGTGATGTCTGTTCCAAATCTTTTGCAAAATTGAAGGGATTAAAAgaacataaaaaattacatgGCGATCTTAAAAGGCCTTATGTCTGCAATATATGTCATAAGGCTTTTTACAAATCTTCCATTTTAGAGAAACACTCATTGACACATACAGGTGAAAAGCCCTTCGCTTGTGATTTATGTGGAAAAAGTTTCCGCCAGAAGGGTCATTTAAGAGATCATATTAACGTTCACAATGATTTGACTCCACATAAATGCAAACTATGTCATAAAGGTTTTCACTCTAGATCCGCTTTAAAAGtacacaaattattgcacacaaAAGAAAAACCTTTTCCTTGTGACATTTGTGGCAAAGCATTTAATCGAAAATGTCATTTGAATGCACACAAAATTATACATACCGAAGAGAAGTCATTTTCTTGTGATGTATGTGAAAAAGCCTTCCGTCAAAAGTACCAactcaaaaatcataaaaatacacacattAATATTAAACGTCGTACAGTTAACAAAAAAATTCCGTGTGATATCTGTAAAAAGGAATTTAGAAGTCAGTGGCATCtaaatttacatacaaaaacaCATACCGGAGAAAAGCCATTTTCTTGCGACCTTTGTGGCAAATCTTTTACTCAAAAAGGCCATATGATGAGACATACAAGATGTCATTCAGATTTAAAATTATTCACCTGTGTTTGTCAGAAGAAATTTAGGAATGAACAACATTTAAAGAATCATTCTTTgcgttgtaataaaattaaggaGATGAATACCAAGAAGactgaaatagaaaataatgatattaaagaagaaattgaaGATGAGAAAAATATAGAATAG
Protein Sequence
MSTKIKIKEEPADFCDYSSGHLFEDDTIKEENFSNEDENITIKIEKETNMLNYAIEVEIDAVKKEVVFNEPEESVNVLIDKSEISNFECDNEGSSSHTEGGNIAGVKSISSESLIEELPLKIEILNDEEKPYNCDVCSKSFAKLKGLKEHKKLHGDLKRPYVCNICHKAFYKSSILEKHSLTHTGEKPFACDLCGKSFRQKGHLRDHINVHNDLTPHKCKLCHKGFHSRSALKVHKLLHTKEKPFPCDICGKAFNRKCHLNAHKIIHTEEKSFSCDVCEKAFRQKYQLKNHKNTHINIKRRTVNKKIPCDICKKEFRSQWHLNLHTKTHTGEKPFSCDLCGKSFTQKGHMMRHTRCHSDLKLFTCVCQKKFRNEQHLKNHSLRCNKIKEMNTKKTEIENNDIKEEIEDEKNIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-