Ahis017127.1
Basic Information
- Insect
- Apocheima hispidaria
- Gene Symbol
- PZF1
- Assembly
- GCA_947579745.1
- Location
- OX388150.1:11760079-11764646[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00024 0.015 15.9 1.6 1 23 15 37 15 37 0.96 2 10 1.2e-05 0.00076 20.0 1.2 1 23 43 68 43 68 0.95 3 10 2.2e-06 0.00014 22.3 3.6 1 23 77 100 77 100 0.97 4 10 0.00088 0.055 14.2 3.9 1 23 106 128 106 128 0.98 5 10 0.003 0.19 12.5 1.7 1 23 134 156 134 156 0.98 6 10 3.6e-05 0.0023 18.5 1.2 1 23 159 182 159 182 0.97 7 10 9.5e-06 0.0006 20.3 3.4 1 23 187 209 187 209 0.98 8 10 9.5e-06 0.00059 20.3 0.5 1 23 219 244 219 244 0.95 9 10 1.4 89 4.1 0.1 1 16 249 264 249 266 0.85 10 10 1.6 1e+02 3.9 0.4 12 23 269 280 268 280 0.89
Sequence Information
- Coding Sequence
- ATGAATAAAAATAATGAAAAAGACGCGAAATCAGATAAACGGCATGTTTGTCAAACATGTGGCTCCTCATTTAATAGACCATATAGATTAACGCAACATTTGTTACTACACCAAAACATTAAAATATTTCAATGCGGTGAAGAAGGTTGTGACAAATCTTATACAAGCAAGAGTCATTTGGATCGACATCTTTATAGTGTGCACATAAAGCCGGATTTTGGTGTTGTTCATAGGTGTCCAGATTGTATGAAAACATTTTCAAACCGCCAAAACCTGAAGAGGCATATAAAAATAAAACATGAGACAAAGACTGCATTTAAGTGTGATATATGCCGGGCTGACTTTAGGAAAAAACACCTTTTGAGTTCTCATATGTACAAACATACACTTGTTAAACCTTTTAGCTGTGAGCTATGCAGTAAAGAATTTATTTCATTGCTTGAGAAAAAAAAGCACATGAAGTATCACAAAACTTACAATTGTGACAATTGTGACATGGCATTTGATCAGTGGTCAAAATATCAGAAGCATAAAAAATCAGAACATGACGTCAAAGAGTATAATTGCAATGATTGTGGGAGAAAGTTCAAACAGAGAGAACACATAGTGCGCCATGTCAAAAAGCACATGTTGGCTAAACCCAAGCCTAAAAATTATATGTGCTGGTACCAAGACTGTGAGAGAGTTTATTCCAGAAACAGTAATCTGAAACAGCATATTGAGATGAGGCACATGCAGCTAACACATACTTGTGAAATATGTGACGCTCAGTTATCGTCTAAGGTAAAACTCCACGCTAATATTAATAATACAACGTTAAAAGCACATCTGAAGACTCACTGCAAGCCTGAAGAATTGTGCTTAAAACACATTTCAATCAGAAAACATCCGAAAACAAAGGAAACTGGACGTAAAGATAGAAAGGATAAAGGATCTTTTAGAAATTCCACTGCTCTTAAAATTGCTGGTCTCATAAATGGTGAAAATGAGAAATTGAAAAAAGAAATTGCTAATGAATCTGTTCAAAGCGAAAATGTGCTCAATTCACAAAAAACTAAAGACCACGTTGTAATGTCCACGGTGTCTGGAAAAAATATGCCAAATAGTGAAGAGGACGACAGAGCTAACACAGTCCCTGATTCCATTATTAACATCTCTCTCGAACACATGGATAAAATAGAAACATCAAATGTTGAAATAGACGAAATTAATAAAGAATCTCAAAATTCCGTAGTCGCGTCTAAGGTAGCCATAGAAGTTGATAATGGTTATTTGCGCCAAGTTGTTGAATCGTTATCTTAA
- Protein Sequence
- MNKNNEKDAKSDKRHVCQTCGSSFNRPYRLTQHLLLHQNIKIFQCGEEGCDKSYTSKSHLDRHLYSVHIKPDFGVVHRCPDCMKTFSNRQNLKRHIKIKHETKTAFKCDICRADFRKKHLLSSHMYKHTLVKPFSCELCSKEFISLLEKKKHMKYHKTYNCDNCDMAFDQWSKYQKHKKSEHDVKEYNCNDCGRKFKQREHIVRHVKKHMLAKPKPKNYMCWYQDCERVYSRNSNLKQHIEMRHMQLTHTCEICDAQLSSKVKLHANINNTTLKAHLKTHCKPEELCLKHISIRKHPKTKETGRKDRKDKGSFRNSTALKIAGLINGENEKLKKEIANESVQSENVLNSQKTKDHVVMSTVSGKNMPNSEEDDRANTVPDSIINISLEHMDKIETSNVEIDEINKESQNSVVASKVAIEVDNGYLRQVVESLS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -