Amei005368.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis mellifera
Gene Symbol
-
Assembly
GCA_003254395.2
Location
NC:3791328-3802761[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0047 0.28 10.8 0.0 2 23 141 162 140 162 0.93
2 10 2.4e-07 1.5e-05 24.3 1.0 1 23 168 190 168 190 0.98
3 10 0.00075 0.045 13.3 1.8 1 23 196 219 196 219 0.93
4 10 0.11 6.4 6.6 2.5 1 23 225 247 225 247 0.97
5 10 1.4e-06 8.7e-05 21.9 0.4 1 23 253 275 253 275 0.98
6 10 2.5e-05 0.0015 18.0 0.8 1 23 281 303 281 303 0.98
7 10 0.0016 0.095 12.3 5.3 1 23 309 331 309 331 0.98
8 10 1.3e-06 7.8e-05 22.0 3.2 1 23 337 359 337 359 0.98
9 10 0.00096 0.058 13.0 0.9 1 23 365 387 365 387 0.96
10 10 0.0018 0.11 12.1 1.8 1 20 393 412 393 414 0.95

Sequence Information

Coding Sequence
ATGCCCTCCTTCTCTTGCTCCTCCTTTCTCGCATTCTCTGTTTCCATTTACTTCGATCGTGGACACGGAATGTCAGAAAACAACGAGGAGGATAGAACGGGGGGAGGCAATGATCGTAATAACGACAATGATATCAAGGAAACTCGGGTGGACGAAGAGGTGAAGATAATAGGGACGGAGAAACGTTGCGTGCGATGCAAAGAAGTGAAAATCAAGACCGAGGTGCTGGACGAGATCGAGAATTTCTCGGCTAACGACGAGCTCGACATTGACGATGCTTACGAGAACGaggcgaggaggaagaggcACAAGAGGGGGCAGAAGGGGAGGGGTTGCCCCCCGATCAAGAAGGAGGTGAATCTGGACGAATATGTGGATTTCGAGGAGTACATAGAGGCGTTGACTACCGGGAAACGATTGATCTGCAGCGTGTGCAGGATCGAGTTCCCCGACGAGGCGGAGTTCAAGACGCACATGGTGGGGCACAGCCATGGAAAATTGTTCCAGTGCGGTATCTGCAGGAAGCAATTTTcacgGTCGTCTGCGCTCAAGGACCACCTTCGTCTTCACGAGACGTTCAAAGCGTTCATATGCAGGCACTGCAGCCTTCGATTTCAGCAGAGGGACCAGTTGAGGATGCACCAGGCCGAGGTGCACTCGAGCCGAAGGCCGTTCGAGTGCGGTGTCTGCAAGAAGAAGCTGCTCCACCGGCAGTCGTTGCGCGATCACAAGCTGATGCACACGAACGTGAAGCCGTTCGAGTGCTCGATCTGCAAGAAGAGATTCCTCAGGCCGAGCAGCCTCAGGGCGCACATGATCGTTCACACAGCCGACTCGCCGTTCGAGTGCGACCTCTGCCCAGCCAAGTTCAAGAGATCTTCCGTGTTGAAGACCCACAAGTTGACGCACACAGGGGTGAGAAGGTTCGAGTGCGATATATGCAAGCACCGGTTCCATTTGAAGGGCGCTCTCAAACATCACATTCTGTCCCATTACGGAGTGAGGCCGTATAAATGCGAGGACTGCGGTAAATGTTACAGGAGGTCGTGGGGCCTGAAGGTGCACAGATATCGTCACACAGGTGTGAAACGATTCGAGTGTGACCTGTGCAAGTCACGATTCAGCGTGAAAACGAAGCTGGCCAAGCACATTTACGGCCACATCGGGGAAAAACCGTACAAGTGCGATTTCTGCGGTCGCCAATATGGCGAACGTTACCAATTGAAGGCGCACAAATGCGGGAACCCATCCAAGACGAGGATCGACAGATCGTTCGCCGACTCCATCACCCAGATCGTCTTCTTCCATCCAAAATCGACCAACATCTCGTTCGATTCAAGTACAAAGAGTTTTATCCAACTGTGA
Protein Sequence
MPSFSCSSFLAFSVSIYFDRGHGMSENNEEDRTGGGNDRNNDNDIKETRVDEEVKIIGTEKRCVRCKEVKIKTEVLDEIENFSANDELDIDDAYENEARRKRHKRGQKGRGCPPIKKEVNLDEYVDFEEYIEALTTGKRLICSVCRIEFPDEAEFKTHMVGHSHGKLFQCGICRKQFSRSSALKDHLRLHETFKAFICRHCSLRFQQRDQLRMHQAEVHSSRRPFECGVCKKKLLHRQSLRDHKLMHTNVKPFECSICKKRFLRPSSLRAHMIVHTADSPFECDLCPAKFKRSSVLKTHKLTHTGVRRFECDICKHRFHLKGALKHHILSHYGVRPYKCEDCGKCYRRSWGLKVHRYRHTGVKRFECDLCKSRFSVKTKLAKHIYGHIGEKPYKCDFCGRQYGERYQLKAHKCGNPSKTRIDRSFADSITQIVFFHPKSTNISFDSSTKSFIQL