Amei000443.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis mellifera
Gene Symbol
ham
Assembly
GCA_003254395.2
Location
NC:7408244-7531765[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0031 0.19 11.4 0.7 2 23 307 329 306 329 0.96
2 9 0.11 6.9 6.5 0.1 1 23 336 359 336 359 0.93
3 9 8.6e-10 5.2e-08 32.0 0.8 1 23 365 387 365 388 0.96
4 9 3.5e-06 0.00021 20.7 2.6 1 23 394 416 394 416 0.95
5 9 2.1e-05 0.0013 18.2 5.0 1 23 422 444 422 444 0.99
6 9 0.00043 0.026 14.1 0.7 2 21 452 471 451 472 0.95
7 9 5e-09 3.1e-07 29.6 1.2 1 23 840 862 840 862 0.99
8 9 2.6e-07 1.6e-05 24.2 1.7 1 23 868 891 868 891 0.97
9 9 7.4e-06 0.00045 19.6 3.4 1 23 897 919 897 919 0.99

Sequence Information

Coding Sequence
ATGATATTCGAGAGGAATCGAAGCAGCGACGAAGGCGAGTCGACGTCGGGCACGCCAGCCGGGGGAGGCACGGGGGGTAGCGGGGAGAGCCAGGAAATGGAGGAGAACGGTACGATCCGTGGCGGAAGCAACAATTCCGCCGGCAATCTGGTGTACAGGGATCTGAAGGCCCTTCACCCGTCAAGCCACGACGTGTCCTCCCAGGATTACAATCCGCAATCGAGGCCGTCGTACCAGCGTGGCTACTCGCCGGCCATGGACAAGCCGAGTTACGAGAAGGAGCAGCACAGACCGCCCTCGTCCAGGGACGAGGAGAAACCTTCCTCGTGGGAGTACGGGGAGAAGACCGAGAGGAAGGAGTACTCGAGATCGCGGGATAGCTTGTACAGGAGCGAAGCGTATCAGGACGCGACGAAGCAGGAGCAGAAGGAGCACGCGAACCGCGAATGGGTATCGCCGGTGCCGGAAGTGGAGGTGGGCGGCTCGGCGCCGGGCGGCCCCCAGGTACGAGCGCGGAAGGACATTCCAAGGGGCGCCAGATTCGGCCCTTTCCTCGGCAAATGGGCCAGCGAGCCTTTCAACCCCCGTTACGCGTGGGAGgTTCGTACGGCCGGAAGCGGGGTGAGGGGGTGGTTGGACGCATCCCACGAGACGAATAATTGGTTGAAGTACGTTCGAAGCACTAGCAGCCCGCACGCGGTTAACATGCGACATGTGCTCATCGGTGGACagATGGTGTACGAGGCGGTGAGGGACATTGCGGCGGGTGAAGAGCTTCTTCTCGGTGTTCGAGAACCTCTTCAGCTTCAGGACATGCTCGGCGAGAATACGACCGAGGATCGAAGCGACCGAGAGACCGCCTCGCAACACAGTGGAACCGTAGACGAGGACaaggaggacgaggaggagggcgAGACTAGATGCACCGTCTGCGACAAACCGTTTCAAGATATCGAATTATTGGACAGCCATCTGATAACCTGTCACAGATACCCGGCGGAGCAGCATCGGTGCGACAATTGTCCCAGAGCGTACGCCTGGCGACCGTTGTTGGTACGCCACCGAGCGATCGTTCACGGTGATCTTCGGAACTACCCTTGCGAGAACTGTCCGAAGGTCTTCACGGACCCGTCCAATCTTCAGCGCCACATCCGGACCCATCACGTGGGCGCGAGGAGCCACGCGTGCACCGAGTGCGGCAAGACGTTCGCGACCAGCTCCGGGCTGAAGCAGCACACCCACATCCACAGCAGCGTGAAGCCGTTCCAGTGCGAGGTCTGCTTCAAGGCGTACACCCAGTTCTCCAATCTGTGCCGGCACAAGCGCATGCACGCCGATTGCCGTATGCAGATCAAGTGCGTGAAATGCGGCCAGTCGTTCAGCACGGTCACCTCGTTGTCCAAGCATAAGCGATTCTGCGACTCGACGCCACCTACCGGCCCGCCAGGCGCCATGCCGCAGTTGCCCACCCCGGCCCCCAGCCCTTTCCTCGTTTACCCCAGACCCCCGGTCAGCCTCCCCGGAGGTTTGCCCTTCTACCCGACCAGCCTGATGGGCCCCTACCCGGGAATCTTCCCCAACGCTCCCAATTTCTTGAACACCCCCCTCCTGTTCCCGCCCAAGGTCGAGGAAGCCGAGAAGAGGAGCGAGAGCCCGAAGAAGGAACGTTTCACCCCGCCAAGGGTTCTGCCGCAGCACAGCAAAGTGTCGCCGTCCACCGCCGAGGAGGCGACCTCCTCGTTCAGACCGTCTCCGGCCAGGCCGCCTGTCCAGCCGACCCCCGAGAGCGACGACCAAGACCCGTCCAAGAAACGGGAGATCGGAAGAGCGGGCAGCGAGAAGAAACCGGATCCCGAGCATACCGCGTCCACGACCACCGCGTCGTCCGCGAACGTCGAGGAGACGACGGATCAGCCGTTGGACCTCAGAGTGCAAACCAAGAAGCAGAGGACGAATTGCTCGAACGCGACGGCCGAGAGGAAGCCGAGTCGCAGCCCGTCCCCGGCCCCGGCTCGGGTCGAGGAGGTCCCGCCGCCCCCCGACCCTCCCAAGCCCGAGGAGGAGGGGGCCGCCTCCGTGCCGATGGAGGTCGACTCCAAGGACGTGGCGAGCAGCCCCCAGCTGAGGACCAGCCTGCCCGCCGAGCAACCGCCCACCAACACCCCGCCGCACATGGCGTACCCAAGACCCATCCACCCCATGTTCCTCGAGGCGATGTACCGCGGCCCGACCGGCTCGTTCCCCGGCTTCCCGGGCGGGCCCCCGCCCCCCGGTGGCGCCGCGCCCGAGTCCAGGCTGCTGCCGCCCCTGCCACCCTTCGGACCACCCCGCGGGCTTCCTTTTTTAGGGACGCTCATGAACGGGCTCAGCGGCGCTAGGCCTGGAGGCGGAGGATTCGACCTGCTCGCCAGGCCGCCGCTGGGGCCGTTCCCCGGCGTGAAACCGTTTCAGGAGGCGGTGATCGCGcctcaccaccaccaccaccaccaccacgccCACGGCAAGATGAAGGATCGGTACTCGTGCAAGTTTTGCGGCAAGGTGTTCCCCAGATCCGCAAACTTGACCAGACACCTGCGCACCCACACCGGCGAGCAACCGTACAAGTGCAAGTACTGCGAACGGTCGTTCAGCATCTCGAGCAACCTGCAACGGCACGTGAGAAACATCCACGACAAGCAGAGGCCGTTCAAGTGTCCCCTGTGCGAGAGATGTTTCGGCCAGCAGACGAACTTGGACCGGCATCTGAAGAAGCACGAGGCCGACGACGGGAGCGGTGTCGTTTCCGTGGCCGACTCGCCTGGGAGCAGCAACGAGAACGAGCGCGAGGACACTTACTTCGACGAGATCAGGTCGTTCATGGGCAAAGTGACTTACGGGGGTGAAGCTGGTTACGGATTGCCGCCCCATCCGGCCTATCTGCCCAGTCGGCTTCACGAGATGCACGAGTCCAAGATGGAGACGGAGtacgacgaggacgaggacagCGAGGAAGGGGTGTCCCCCCTGGACGAGACGGATGGCATGTCCCCGGCCGAGACCAAGGAATCGGCAACCCCGCCGCCCCAGTACGATCTCAAGCTGAGGGAGAAGCAGGAACTGCTCAACAACAACACGGCCGAACCCGTGATCGAGATCTCCACATAG
Protein Sequence
MIFERNRSSDEGESTSGTPAGGGTGGSGESQEMEENGTIRGGSNNSAGNLVYRDLKALHPSSHDVSSQDYNPQSRPSYQRGYSPAMDKPSYEKEQHRPPSSRDEEKPSSWEYGEKTERKEYSRSRDSLYRSEAYQDATKQEQKEHANREWVSPVPEVEVGGSAPGGPQVRARKDIPRGARFGPFLGKWASEPFNPRYAWEVRTAGSGVRGWLDASHETNNWLKYVRSTSSPHAVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLITCHRYPAEQHRCDNCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTPAPSPFLVYPRPPVSLPGGLPFYPTSLMGPYPGIFPNAPNFLNTPLLFPPKVEEAEKRSESPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDQDPSKKREIGRAGSEKKPDPEHTASTTTASSANVEETTDQPLDLRVQTKKQRTNCSNATAERKPSRSPSPAPARVEEVPPPPDPPKPEEEGAASVPMEVDSKDVASSPQLRTSLPAEQPPTNTPPHMAYPRPIHPMFLEAMYRGPTGSFPGFPGGPPPPGGAAPESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGMSPAETKESATPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01539779;
90% Identity
-
80% Identity
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