Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:7677418-7688077[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.5e-06 9.4e-05 21.8 1.7 1 23 268 290 268 290 0.98

2 9 1.5e-08 9e-07 28.1 1.6 3 23 298 318 296 318 0.98

3 9 0.00011 0.0069 15.9 0.4 1 23 324 346 324 346 0.98

4 9 6.3e-07 3.9e-05 23.0 1.5 1 23 352 374 352 374 0.99

5 9 1.1e-05 0.00068 19.1 1.7 2 23 488 509 487 509 0.96

6 9 1.4e-09 8.7e-08 31.3 1.6 1 23 515 537 515 537 0.98

7 9 0.00032 0.02 14.5 0.6 3 23 545 565 543 565 0.97

8 9 4.3e-05 0.0026 17.2 1.4 1 23 571 593 571 593 0.99

9 9 0.0096 0.59 9.8 0.8 1 23 599 623 599 623 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.5e-06	9.4e-05	21.8	1.7	1	23	268	290	268	290	0.98
2	9	1.5e-08	9e-07	28.1	1.6	3	23	298	318	296	318	0.98
3	9	0.00011	0.0069	15.9	0.4	1	23	324	346	324	346	0.98
4	9	6.3e-07	3.9e-05	23.0	1.5	1	23	352	374	352	374	0.99
5	9	1.1e-05	0.00068	19.1	1.7	2	23	488	509	487	509	0.96
6	9	1.4e-09	8.7e-08	31.3	1.6	1	23	515	537	515	537	0.98
7	9	0.00032	0.02	14.5	0.6	3	23	545	565	543	565	0.97
8	9	4.3e-05	0.0026	17.2	1.4	1	23	571	593	571	593	0.99
9	9	0.0096	0.59	9.8	0.8	1	23	599	623	599	623	0.95

Sequence Information

Coding Sequence: ATGGAGAGACCCCAGGGGCAATGGGGCCCCGGGCCGGGATCTCTCCAGGACGGGGGGCTGTACCcgcagcaacagcaacaacagcaacagcagGGCTCCTCCTCGTCCGGCAGCCCACAGCAGGCCTGTGGTCCCCCTGTCGAGGGAGAAAGCGGTCCCCCGCCTTCGTTGGCCTCTCCCGTGCCCTCACCGTACCCCTCGGCACCGCCTGAGCCTCAAGCCTTAACCCCACCCGACGACGATATACAATCGAATCAAGCCACCTctcaacagcagcagcaacagcagcagcagcaacaacagcagcagcagcagacGCAGCAACAAgtgcagcagcagcagcagcagcaacagcagcagcaacaacagcagcagcagcagcagcaagttcaacagcagcaacagcagcaacagcagcaacaacagcagcagcagcaacagacGCAGCAACAGGACCACTCGCCCCAACAACAGTTAACCCCTCACGAGGTGGATCGCGCGGATTGTTTCCCAGGGGCGGGAGAGCTGCAGCAGTATCCGCAGCACTACTTCAAGGATGCCAGGCCGCATCCGTCGCCGTCGGTGCCACCGCACATGCTGACCCCGGGTGGTTTCTCCGCGTTGCACTATCTGAAGCAGCCGGGCGTGATGCTCACGTCCCTCGGGCAGGGGGACGGTGGACCCAGCCTGGACGCGCACCAATACGCGAGCCCCGGGGCACCGAACATGGCGACCGGGCTGCCGGACATCGTCCAGCAGAGCGGCAAGTCTGGGAAAGGGGCGAACAGCGACCTACGTTTGTTCAAGTGTTTGACGTGCGGGAAAGATTTTAAGCAGAAGTCGACGTTGTTGCAACACGAGCGGATCCATACGGACAGTCGGCCATACGGGTGTCCAGAGTGCGGGAAGCGGTTCAGGCAACAATCGCATCTAACGCAGCACCTGCGCATACACGCGAACGAGAAGCCGTATGCTTGCGTGTACTGCGAGCGTACGTTCCGGCAGCGTGCCATCCTCAACCAGCATCTGCGCATCCACTCGGGTGAGAAGCCATACCAATGTCCGGAGTGCGGAAAACACTTCCGTCAGAAGGCGATCCTGAATCAGCACGTCCGCACACACCAAGACGTGAGTCCGCATCTAATCTTCAAGAATGGGATGACGCCGACACTCTGGCCCCAGGACGTTCCGTTTCCgcaggaggaggggaaggaggaggtgGGATCGACGTTCGGCGACACGGACACGCAGTCGGGCGCGTTCAGCCCGGCGCCGGACGCCAACTCGATCCAGTATCCCGCCTACTTCAAGGACCCGAAGGGCGGGAATCACGCGGTTTTCGGTGCGGGTGGCACGGGCAGCTTCGGCGCCCTCCAGTACATCAAGCAGCAAGGCGGCAGCAAGAGCTGTCTGCCGGACGTGATACAGCACGGCCGCTCCGCGGGCATGCCGTTGTACGTTCGGTGCCCGATCTGTCAGAAGGAGTTCAAGCAAAAGTCCACGTTGCTGCAGCACGGGTGCATACACATCGAGTCGCGGCCGTACCCTTGCCCCGAGTGCGGCAAGAGGTTCAGGCAACAGTCCCACTTGACCCAACACCTTCGCATCCACACCAACGAGAAGCCGTACGGGTGCGTGTACTGCGGCCGTAACTTCCGCCAGCGCACCATCTTGAATCAGCATCTGCGCATCCACACGGGCGAGAAGCCGTACAAGTGTCAACAGTGCGGCAAGGATTTCCGCCAGAAGGCGATACTGGACCAGCACACGCGCACCCACCAGGGCGATCGGCCCTTCTGCTGCCCCATGCCCAACTGTAGGCGACGCTTCGCCACCGAGCCCGAGGTGAAGAAGCACATCGACAACCACATGAATCCGCACGCGGCCAAGGTGCGCAGGAACTCGAGCAGCGACTCCAAGCCGCCCGGCACGCCGGCCGGTCTTGGCCCCGTCCCCGTCCCCAGGGGGTTGACGCCGACCGTGGTCAAGCCGGAGCTCTACTTCCCCCAATGTTACGCGCCCGCGTTTAATCACCAACCCCCGGTGTCGACGGCGCAGTTCCCGGCACAGGCGAACGGGGTGTCCGTCGCCGGCGAGTTCAAACCACCGACCGGCCTGCCGCCGCAGTGA
Protein Sequence: MERPQGQWGPGPGSLQDGGLYPQQQQQQQQQGSSSSGSPQQACGPPVEGESGPPPSLASPVPSPYPSAPPEPQALTPPDDDIQSNQATSQQQQQQQQQQQQQQQQTQQQVQQQQQQQQQQQQQQQQQQQVQQQQQQQQQQQQQQQQQTQQQDHSPQQQLTPHEVDRADCFPGAGELQQYPQHYFKDARPHPSPSVPPHMLTPGGFSALHYLKQPGVMLTSLGQGDGGPSLDAHQYASPGAPNMATGLPDIVQQSGKSGKGANSDLRLFKCLTCGKDFKQKSTLLQHERIHTDSRPYGCPECGKRFRQQSHLTQHLRIHANEKPYACVYCERTFRQRAILNQHLRIHSGEKPYQCPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGMTPTLWPQDVPFPQEEGKEEVGSTFGDTDTQSGAFSPAPDANSIQYPAYFKDPKGGNHAVFGAGGTGSFGALQYIKQQGGSKSCLPDVIQHGRSAGMPLYVRCPICQKEFKQKSTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPYGCVYCGRNFRQRTILNQHLRIHTGEKPYKCQQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATEPEVKKHIDNHMNPHAAKVRRNSSSDSKPPGTPAGLGPVPVPRGLTPTVVKPELYFPQCYAPAFNHQPPVSTAQFPAQANGVSVAGEFKPPTGLPPQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01418493;
90% Identity: iTF_00684322;
80% Identity: -