Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:12100655-12103824[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00012 0.0072 15.9 3.7 1 23 292 314 292 314 0.97

2 12 5.7e-05 0.0035 16.8 3.5 1 23 318 340 318 340 0.98

3 12 0.00034 0.021 14.4 3.1 3 23 347 367 345 367 0.96

4 12 0.00051 0.031 13.9 3.3 1 23 419 441 419 441 0.97

5 12 0.00053 0.032 13.8 1.4 1 23 446 468 446 468 0.97

6 12 0.00019 0.012 15.2 2.3 1 23 517 539 517 539 0.98

7 12 1.4e-05 0.00084 18.8 0.4 2 23 547 568 546 568 0.97

8 12 6.6e-07 4e-05 22.9 2.1 1 23 578 600 578 600 0.96

9 12 0.00015 0.0091 15.5 1.6 1 23 606 628 606 628 0.97

10 12 0.00011 0.0065 16.0 0.7 1 23 634 656 634 656 0.98

11 12 3.2e-06 0.00019 20.8 2.0 1 23 662 684 662 684 0.96

12 12 5.7e-05 0.0034 16.9 0.3 1 22 690 711 690 711 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00012	0.0072	15.9	3.7	1	23	292	314	292	314	0.97
2	12	5.7e-05	0.0035	16.8	3.5	1	23	318	340	318	340	0.98
3	12	0.00034	0.021	14.4	3.1	3	23	347	367	345	367	0.96
4	12	0.00051	0.031	13.9	3.3	1	23	419	441	419	441	0.97
5	12	0.00053	0.032	13.8	1.4	1	23	446	468	446	468	0.97
6	12	0.00019	0.012	15.2	2.3	1	23	517	539	517	539	0.98
7	12	1.4e-05	0.00084	18.8	0.4	2	23	547	568	546	568	0.97
8	12	6.6e-07	4e-05	22.9	2.1	1	23	578	600	578	600	0.96
9	12	0.00015	0.0091	15.5	1.6	1	23	606	628	606	628	0.97
10	12	0.00011	0.0065	16.0	0.7	1	23	634	656	634	656	0.98
11	12	3.2e-06	0.00019	20.8	2.0	1	23	662	684	662	684	0.96
12	12	5.7e-05	0.0034	16.9	0.3	1	22	690	711	690	711	0.96

Sequence Information

Coding Sequence: atgacagaatattttgatttaccaCTTAATATGGACAGAATATGTAGAATTTGCCTTACAGAAGGTACTAATTTATCACCTATTTTTTGTACGGATCAAGAAGTGAATGATTTCTCGGCTCTTCCTCAAAAGATACAAGTTTGTGGATCAATAGAAATTCATGAACAAGATGGATTACCTTCATTAATTTgtgatatttgtatttataaagcaAGTGTTGCTCATGAATTTAGACAACAATGTCAACATTCTGATGCCAAATTacgaatgtattataataaaccatctaaaattactattgtggatACATGTACACAAACTGAATCTGAGATAAGAACATTGTTATCTAAAGAACAAATTAATCaagagaattattttgtaaaagagGAAATGCATGTAGCATCAAATTCTCAAGAATATGTACAAACTAATGATTCATATTGTAGAGATGAATCTAACTTAAGCACCAGCCAAATTGATATGCAGAAtgagaaactttttatttgttcTATTGGATTTGAAGGAcctaaagaaattgaaaaagaatcttgtacttcagaaaataatatacatgagGCATCTCTTACACAAGAaatcaataatgatatttctgaaactataaatatgcaaaataaacCAGAAGAAAATCAAGATATCAATCAAAATTCAGAGGAAGATGATAGAAAACAAGAAGTagaattttttgatgaaaatatattaaatgataacgttaaagaagaagaagaagttgtGCAGAAACGTACTTCTACTAGGAAAGTAAAATCAGTGCCTAATAAAACTTATAGCGAAGATGAAAttcatgataattattatgactCAAGTAATGATGGTGAAGATTctggagaattaaaatttaaatgtaaagtaTGTGCAAAATGTTATAGCACACAAAGAGGCTTAAAGAAACATTCCCTTgttcatgaaaaaaaacataaatgcaatatttgttcaaaaatgttttatagatTAGAGAATAtggaaaatcataaaaaaatacatgcaTCAAAACCACTTGCATGTCAATTATGTCATGCATGTTTTTCTAAACCTCAAAGTCTTGTACGTCATCTAAAATCTCATAcagaaaaagtaaataatatgattaaacaaATTAGTACAGACGAACAAAAAGATAACAAGGAACCAAAAAAAGAGATGAAATTTGAAGATGATACAGATGATGAAAATGGTACTGTGAATGAAgtttatgattttgaaaatgcaCCTGAGTTGTACAAATGTGAAATTTGTAGTCAATATTgttcttcattaaaaaatctaaaaagacATAGTCTTGTACAtggagataaaaaatattcctgtACTGTATGTAAAAAATGGTTTTTTAGGCctgatacattaaaaaaacatgCAGAAAAACATGGTCATggattattagataatttagtagatgataataaattttttgattctgaTGATGATTCTTTCCCAAGTACTACTCAAAATACTTtacaagaaaatgaaaatgttaaaaaagaagaaagtgatGAAGATGATTCTGGTGAATATAAATGTCAACATTGTGATAAAATTATGGCAACAAAGAAAGGTCTTAGACGTCATGTATCAATGCATAAACCAAAAGCTGAACCAGTTACTTGTGAAATCTGTGGAAAGGTATGTGCTAGTCAAGCTCGTCTTGTTCTTCATCAAAGGACACATAAACCAAAAGAAAAGGTTCCAAGAGAATATTTATGTCACATTTGTAGTAAGGTGTATCCAAGTAATTCTTCTCTAACTTATCATATGAGAACTCATACTGGTATTAAACCACATGTGTGTAAAACTTGTAATAGTGGATTTACTACAACAACCAGTTTAGCAAATCACATTAGAATTCATACAGGTGATAAACCATTTGTTTGTCATGTATGCAGTGCTGCATTTGCTGTGAGTTCAGCTTTTAGACGACACTTGACTCGACATACTGGAGAAGCAAATTATTTGTGTAAAACATGTGGCAAAGCATTCAAAAGACTAAGTACTTTAAAAGAACATACTTATACTCATTCTGGTGAAAAACCATATGTGTGTAAAACTTGTGGAGCTGCTTATAGCCATAGTGGTAGTTTGTTTGCACATCAGAAACGTTGTCGAGCTCAATATGGAGAGATGGTTGTAGATGAACATCATCATACAGTTGCTCACCATATTCATGTAAATAATGTGCAATCTGCAGTACGATCACTTGCTGTGATAGgacaaatgttttaa
Protein Sequence: MTEYFDLPLNMDRICRICLTEGTNLSPIFCTDQEVNDFSALPQKIQVCGSIEIHEQDGLPSLICDICIYKASVAHEFRQQCQHSDAKLRMYYNKPSKITIVDTCTQTESEIRTLLSKEQINQENYFVKEEMHVASNSQEYVQTNDSYCRDESNLSTSQIDMQNEKLFICSIGFEGPKEIEKESCTSENNIHEASLTQEINNDISETINMQNKPEENQDINQNSEEDDRKQEVEFFDENILNDNVKEEEEVVQKRTSTRKVKSVPNKTYSEDEIHDNYYDSSNDGEDSGELKFKCKVCAKCYSTQRGLKKHSLVHEKKHKCNICSKMFYRLENMENHKKIHASKPLACQLCHACFSKPQSLVRHLKSHTEKVNNMIKQISTDEQKDNKEPKKEMKFEDDTDDENGTVNEVYDFENAPELYKCEICSQYCSSLKNLKRHSLVHGDKKYSCTVCKKWFFRPDTLKKHAEKHGHGLLDNLVDDNKFFDSDDDSFPSTTQNTLQENENVKKEESDEDDSGEYKCQHCDKIMATKKGLRRHVSMHKPKAEPVTCEICGKVCASQARLVLHQRTHKPKEKVPREYLCHICSKVYPSNSSLTYHMRTHTGIKPHVCKTCNSGFTTTTSLANHIRIHTGDKPFVCHVCSAAFAVSSAFRRHLTRHTGEANYLCKTCGKAFKRLSTLKEHTYTHSGEKPYVCKTCGAAYSHSGSLFAHQKRCRAQYGEMVVDEHHHTVAHHIHVNNVQSAVRSLAVIGQMF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962662;
90% Identity: iTF_00223348;
80% Identity: -