Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:8180245-8191464[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.25 15 5.4 5.4 1 23 390 412 390 412 0.98

2 19 0.00024 0.015 14.9 0.7 2 19 448 465 447 469 0.89

3 19 4.3e-05 0.0026 17.2 4.5 1 23 475 497 475 497 0.98

4 19 0.00022 0.013 15.0 0.1 3 23 505 526 503 526 0.94

5 19 0.27 17 5.3 1.8 1 23 533 556 533 556 0.98

6 19 2.3e-05 0.0014 18.1 0.8 1 23 560 582 560 582 0.97

7 19 0.002 0.12 12.0 0.6 1 23 588 610 588 610 0.98

8 19 0.00012 0.0071 15.9 2.3 1 23 616 638 616 638 0.96

9 19 0.0018 0.11 12.1 0.1 1 17 643 659 643 660 0.90

10 19 9.9 6e+02 0.4 0.6 2 10 1186 1194 1185 1203 0.89

11 19 0.45 27 4.6 1.6 1 23 1213 1236 1213 1236 0.98

12 19 0.00011 0.0067 16.0 0.4 1 23 1242 1264 1242 1264 0.97

13 19 1.2 70 3.3 0.8 1 23 1270 1292 1270 1292 0.85

14 19 2.5e-06 0.00016 21.1 0.3 2 23 1299 1320 1298 1320 0.96

15 19 0.11 6.9 6.5 0.2 2 23 1327 1349 1326 1349 0.94

16 19 4.1e-05 0.0025 17.3 2.8 1 23 1353 1375 1353 1375 0.98

17 19 0.017 1 9.1 0.8 1 23 1380 1402 1380 1402 0.98

18 19 1e-07 6.1e-06 25.5 0.5 1 23 1408 1430 1408 1430 0.98

19 19 1.3e-05 0.00077 18.9 0.8 1 21 1435 1455 1435 1456 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.25	15	5.4	5.4	1	23	390	412	390	412	0.98
2	19	0.00024	0.015	14.9	0.7	2	19	448	465	447	469	0.89
3	19	4.3e-05	0.0026	17.2	4.5	1	23	475	497	475	497	0.98
4	19	0.00022	0.013	15.0	0.1	3	23	505	526	503	526	0.94
5	19	0.27	17	5.3	1.8	1	23	533	556	533	556	0.98
6	19	2.3e-05	0.0014	18.1	0.8	1	23	560	582	560	582	0.97
7	19	0.002	0.12	12.0	0.6	1	23	588	610	588	610	0.98
8	19	0.00012	0.0071	15.9	2.3	1	23	616	638	616	638	0.96
9	19	0.0018	0.11	12.1	0.1	1	17	643	659	643	660	0.90
10	19	9.9	6e+02	0.4	0.6	2	10	1186	1194	1185	1203	0.89
11	19	0.45	27	4.6	1.6	1	23	1213	1236	1213	1236	0.98
12	19	0.00011	0.0067	16.0	0.4	1	23	1242	1264	1242	1264	0.97
13	19	1.2	70	3.3	0.8	1	23	1270	1292	1270	1292	0.85
14	19	2.5e-06	0.00016	21.1	0.3	2	23	1299	1320	1298	1320	0.96
15	19	0.11	6.9	6.5	0.2	2	23	1327	1349	1326	1349	0.94
16	19	4.1e-05	0.0025	17.3	2.8	1	23	1353	1375	1353	1375	0.98
17	19	0.017	1	9.1	0.8	1	23	1380	1402	1380	1402	0.98
18	19	1e-07	6.1e-06	25.5	0.5	1	23	1408	1430	1408	1430	0.98
19	19	1.3e-05	0.00077	18.9	0.8	1	21	1435	1455	1435	1456	0.94

Sequence Information

Coding Sequence: ATGGAGTTAGGGGAGGGAGAAGCTCAAATTTGTCGACTTTGCGGTCAATGTGAAAGTATATACATTGATGTGTTCGGTGAAGAAGGCACCAAACGATTTTTAGGcttaaaaattcatacaaGAATCAACATTTTGATAGATGAAAGGGATCCTCTGCCCAAGGCGATCTGCGTTCAATGTCTGGGCAAACTCGAATTTGTTTGCGACTTCCAAGAGGAGTGTCTTCGCACCCAACAAGTGTTACGCGATCGATACATTCTACCATCCTTAACAGAGATTGCTGAAGTAAAGACTGAAGTTACACCAAGTACATCAAcatacaacaacaacaatgacaccaatataaatcttaattcttCAAATGATGAGGACATTCAAAAAATAGATCAGCATGTCCTAAGAACAACTACAAAAACTcaaaaaaatacgaagaatCAACAAGTAAAAGGCAATGAAGAAACTTCCAAAGATCAaactaatattcaaaatacgagtgaaaaaaatactGAGAATGcacaaattcaaaaatgtgACACAACTCCTACACGATGGCTTAGAAGTAGACAAAGTATAGAAACAACTGTTACAAATGAAACAGCTACTGATACACCAATTGCAAATAGACTTAGAAGTCATGATAATACTACCACAGAATTAACTGTTAGTCCACGTAGTTGTTCTAAGgaaaatagtgaaaaattGACTGGAAAACAAGATCCACATACTATTCAAATTCCAACATCAGCATTAAATAAACTTCTCAGTATTGTGTCAAATTCTCCAAATATTGAAGTTTCTGTGAAAGAATCTAGAAATCAAAGCAGCGATATTGAAGATATTAGTTTCACTGTAGAATTATGTAAAAAGGAAAGTGATGATGTAGCTACTGCTCGAGCACGAGTATTTCCAGATCAAGGTTCCTGTTTGGTTGATAAGGCTATAGTTGGTCTTTTACAAAATCAAAGTTGTGTAGAagttaatagtataataaatacaattatcgaTAGTAGTCTGAAAAACGGCAATTCGACAAAATTAGAAGATTCTGCtgaatttgaacaaaaatggCAAGCTTCTCAAAATCCGAAGGAACTTTTCAAGATTGATGGGGAAGAAATTCGTGTCGATGATAACGTTGAACACGTCGttacaaataatcaaaatggTTATTCTTGTAAATTGTGTCGTAAGTTTTATGAACGCAAAGACAAATGTATGGTTCATGTGAAAACACATCTTGGTATTAAACAATACACATGTATTCTATGCAACGCTAAATTTGTATGTAAGTCTGATGTTATGAAACATATTCGATGCACACATACTAATCCGAGACCAATACAATGTCCAAAATGTCCAAAGAGATTCAAGTCAAAGTTCTATTTAATGGAACATGATAATGTACATAAAGGTGTGAGACCTTATTCTTGTACAGATTGCGGTCAAAGTTACCATCATAAAGTATCGTTACAACTTCATATGAAATCACATTTACCTCCGCAAAACTTAGCATGCGAATATTGTGGCAAAGTATTTCCGTATCGTACGAGATTATTAAGTCACATAGCTAgtgtacatttaaaaaatcgtcGCAATTTTAGATGTCGATTTTGTTACAATCTTTATTCAAGTCTTTCAGTTTTGAATGAACATATTAAAACGCGTCATGCGACTACATATACTTGTGAAGTTTGTAATAAAACGTTTAAAGTCGCGTCCAAATATAAGGCTCACGTATTACAACATTCAAATCCTAAGCCATTCGTATGTAATGTTTGTAATAATAGATATGCATCCAAAGCATTCCTAAATGAACATCTATCAAAACACGAAGGGCTGAGGAAACATATCTGCCAAAAGTGTGGTGCAAGATTCGCTCAAGCTAGTCATCTGGCTGCACATCGGCACGTGCACGGTGAAAAAGAGCACGCTTGTCCGGAGTGTGGGCGAAAGTTTAATAGGCGTGATAATATGAAGatAAAAGAGAATGATGGATTGTCACAAGTTGTTTGTATACGATGTTTGGGCACACTGGAATTTCTATGCGATTTTTACGAGCGTTGTCATCTTacacaaaaagaatttttaaaaactagccaaaatcaaaatataataaatgagaaattattgaaagattcCACTAATGATACAGAATcagataaagaaaatgatgCTCCATTTGTAAATGAAAGTAAATGGAAAGCAAAAGTTTTATCAcccaataattcaaaaaaatcaaaaaattatttgtctgaaaataatacatcatacagaatcgaaaataaacaGGAAAACAATGATcagatagataataatatttctattgataATGTTCATTTGATTACAAAaacacaattaaataatataatttctaaaaaccaatctataataaaaaatgtaatttcacatgaaaatatatcaaaaaatgatcaacataatattagtaatttaaaagagaatatgtataatttaaaagaaaatattttggaaaaaaatataaattgcataacaagatcaacaaataatttaaatacatctcaaataaatgaaacaaatgttaataaaaatttagatcaaCCTATACGACGTAAAAGAGGACGAAAaagtaaattagaaaaaataagagaagtaAGTTTAACaacaaactataaaaaaaagattcaaaatcatctaagtgataaaaaaaaagataatgttaataatgaatataaaagatattgtttGCGTACTATTTGTACCACTACTAAGTctgataatgtaaataataatgctaCAATCATATCTAAACCACAAGTTAAACAAACAGAAGTTGAACAGGTGCCAGTAAATACATCAATGAATACAAATTACACCAAAGGTAATAAAACTAATACAATGATTAATAAACTAACTGTAATTGAATCTGATGATAATTCAATAAGatctaataatttgaaagatacagaaaagaattctgaaaaaaataaagcgaTATCGATTATTGTAAAACAAGAGAAAGGAGAAGCAGAAATTTCTTCTAGACAATTGAATCAATTAGTTCTTAATCAAAAGTCAAAagtaaatcaagaaaaaacaGATTTAATATGTGTATTAATGgaaaaaactgaaaatattaaaaatattgaaacgaatttaatagcagaacaaaatattactaaatatcctgatataatttcttccgattataataatcaacaatcaaaaatattcacagAACAAAATCGAGTGACTATTATAAAGTCTTCACAATCTAAAAATgtgacaaatttaaaaataatgcaagaagattgtacaaaattaaataatacaattgatGTAGATCAAAATACTAAAACTGAGGTAGAATGTAATCTTAATGAACATTCATTGCCTCAACAATTAAGtcaaaatagttttaataaaaatcagagTAAAAATAGATCATTTGGCAAAATTTCCGAATTGATAAGTGACGAACAAAAACGAACTATTGAAAGTTATTATACAGTGGACATGTCGATTGTAAACTCAGAAgaagtacaaaaaaatataacaataattaataaaaaaaacatacgtTGCAATATTTGTGGTACTTTTTATCTTAGAATGGATAAATGTCAggTACATATTTGGGGACATTTACAAATGAAGCCCTATCAATGTAAAGCTTGTGATTTTGCCACAGTTACTGTTAGTAATGTTCGTTGCCATATCAGAAAAAgtcatttaaagattaaacCATTTGCGTGCCATCTTTGTGAAAAGCGATATGTAACTGCCATTTTATTAGAAGAACATATTAATACTCATACAGGAGCCCGTCCATATAAATGCAAGCTTTGTGACTTTGCAAGTTCCAGTAGACAAATATTAAGTTACCATAATGCTACTCATAAACCATTAaagGATATTAGTTGTAAGATTTGtggtaaagaattttattcaagaagTAGATTACGTGCACACATGATTGTACACAATAAGGACAAAGCTGTTATGTGTAAATTGTGTTCTGCTTATTTATCTAATGCAGAAGCATTAAAAACACATTACAAGAACATTCATATGCAAGATTATGTCTGTAATATCTGTGGTAAACACGTCAAGTCTAGAAAAGCTTTGCATAATCATCAGAATGTTCATGCTGCTGCAAGATTTAAATGTACTCTTTGcccaaatgtatataaaactagccaaatattaaaagaacatCTTTTAAAACACGAAggtattagaaaatataaatgtaatatttgtgaaaaatcatTTGGTCAACAATCTCATTTAGCTGCTCATATGGCAGTGCACAGTAATATTAgATTCCATTGTCCAGGATGTGATAAGCCTTTTAATCGGCaagataatatgaaaatacataCTAAACGATGCAAACCATTTTTGGCAAATCCAAAtctgaaaaatcttttaagtaaaagagaaagaactatatcgtttaataatatagcAGAATTAACTGCAGAATTGAAGAATGGGAATGTGACAAATTCAATATCTCAAGTTCCTCTCAAAAATGAGAATGATAAAACATTAGTAAAGACtgtagaagaaaaacaaaagacTGTTATAAATCTTTGCAAATTAGGATTAAATATCTCTTGCATTAAaccaacaaataataaaatgagtcCAGATCATATTacaaattcttttgaaaaaaatgtaattaagaaCACAGAtaacaatgataaattaatttcagaaaatgaaaagttgttagtttttgaaaatatgccttaa
Protein Sequence: MELGEGEAQICRLCGQCESIYIDVFGEEGTKRFLGLKIHTRINILIDERDPLPKAICVQCLGKLEFVCDFQEECLRTQQVLRDRYILPSLTEIAEVKTEVTPSTSTYNNNNDTNINLNSSNDEDIQKIDQHVLRTTTKTQKNTKNQQVKGNEETSKDQTNIQNTSEKNTENAQIQKCDTTPTRWLRSRQSIETTVTNETATDTPIANRLRSHDNTTTELTVSPRSCSKENSEKLTGKQDPHTIQIPTSALNKLLSIVSNSPNIEVSVKESRNQSSDIEDISFTVELCKKESDDVATARARVFPDQGSCLVDKAIVGLLQNQSCVEVNSIINTIIDSSLKNGNSTKLEDSAEFEQKWQASQNPKELFKIDGEEIRVDDNVEHVVTNNQNGYSCKLCRKFYERKDKCMVHVKTHLGIKQYTCILCNAKFVCKSDVMKHIRCTHTNPRPIQCPKCPKRFKSKFYLMEHDNVHKGVRPYSCTDCGQSYHHKVSLQLHMKSHLPPQNLACEYCGKVFPYRTRLLSHIASVHLKNRRNFRCRFCYNLYSSLSVLNEHIKTRHATTYTCEVCNKTFKVASKYKAHVLQHSNPKPFVCNVCNNRYASKAFLNEHLSKHEGLRKHICQKCGARFAQASHLAAHRHVHGEKEHACPECGRKFNRRDNMKIKENDGLSQVVCIRCLGTLEFLCDFYERCHLTQKEFLKTSQNQNIINEKLLKDSTNDTESDKENDAPFVNESKWKAKVLSPNNSKKSKNYLSENNTSYRIENKQENNDQIDNNISIDNVHLITKTQLNNIISKNQSIIKNVISHENISKNDQHNISNLKENMYNLKENILEKNINCITRSTNNLNTSQINETNVNKNLDQPIRRKRGRKSKLEKIREVSLTTNYKKKIQNHLSDKKKDNVNNEYKRYCLRTICTTTKSDNVNNNATIISKPQVKQTEVEQVPVNTSMNTNYTKGNKTNTMINKLTVIESDDNSIRSNNLKDTEKNSEKNKAISIIVKQEKGEAEISSRQLNQLVLNQKSKVNQEKTDLICVLMEKTENIKNIETNLIAEQNITKYPDIISSDYNNQQSKIFTEQNRVTIIKSSQSKNVTNLKIMQEDCTKLNNTIDVDQNTKTEVECNLNEHSLPQQLSQNSFNKNQSKNRSFGKISELISDEQKRTIESYYTVDMSIVNSEEVQKNITIINKKNIRCNICGTFYLRMDKCQVHIWGHLQMKPYQCKACDFATVTVSNVRCHIRKSHLKIKPFACHLCEKRYVTAILLEEHINTHTGARPYKCKLCDFASSSRQILSYHNATHKPLKDISCKICGKEFYSRSRLRAHMIVHNKDKAVMCKLCSAYLSNAEALKTHYKNIHMQDYVCNICGKHVKSRKALHNHQNVHAAARFKCTLCPNVYKTSQILKEHLLKHEGIRKYKCNICEKSFGQQSHLAAHMAVHSNIRFHCPGCDKPFNRQDNMKIHTKRCKPFLANPNLKNLLSKRERTISFNNIAELTAELKNGNVTNSISQVPLKNENDKTLVKTVEEKQKTVINLCKLGLNISCIKPTNNKMSPDHITNSFEKNVIKNTDNNDKLISENEKLLVFENMP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -