Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:7619194-7621734[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.038 2.3 8.0 0.9 2 23 126 147 125 147 0.94

2 11 0.00014 0.0086 15.6 2.9 2 23 218 239 217 239 0.95

3 11 1.9e-06 0.00012 21.5 2.5 1 23 386 408 386 408 0.98

4 11 3.9e-07 2.4e-05 23.7 1.5 1 23 414 436 414 436 0.98

5 11 2.5e-07 1.5e-05 24.3 2.1 1 23 442 464 442 464 0.98

6 11 0.00025 0.015 14.8 1.6 1 23 480 502 480 502 0.97

7 11 5.7e-09 3.5e-07 29.4 1.4 2 23 509 530 508 530 0.98

8 11 1.4e-07 8.8e-06 25.0 3.4 1 23 536 558 536 558 0.98

9 11 3.3e-07 2e-05 23.9 4.1 1 23 564 586 564 586 0.96

10 11 4.7e-05 0.0029 17.1 4.4 1 23 592 614 592 614 0.96

11 11 2.2e-05 0.0014 18.1 5.0 1 23 620 642 620 642 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.038	2.3	8.0	0.9	2	23	126	147	125	147	0.94
2	11	0.00014	0.0086	15.6	2.9	2	23	218	239	217	239	0.95
3	11	1.9e-06	0.00012	21.5	2.5	1	23	386	408	386	408	0.98
4	11	3.9e-07	2.4e-05	23.7	1.5	1	23	414	436	414	436	0.98
5	11	2.5e-07	1.5e-05	24.3	2.1	1	23	442	464	442	464	0.98
6	11	0.00025	0.015	14.8	1.6	1	23	480	502	480	502	0.97
7	11	5.7e-09	3.5e-07	29.4	1.4	2	23	509	530	508	530	0.98
8	11	1.4e-07	8.8e-06	25.0	3.4	1	23	536	558	536	558	0.98
9	11	3.3e-07	2e-05	23.9	4.1	1	23	564	586	564	586	0.96
10	11	4.7e-05	0.0029	17.1	4.4	1	23	592	614	592	614	0.96
11	11	2.2e-05	0.0014	18.1	5.0	1	23	620	642	620	642	0.99

Sequence Information

Coding Sequence: ATGTTTATCGTTACAAAAGAAATTGACAGCGAAAACATCGGTAAATTATGCCGTACATGTTTAAGAGAGGATGGTGACAAAATGGTTTGTTTATTCGTGGGACCGGCTGAATCATCCCTTGCTGCGAAATTACGGTCTCTTTCATGTCTCGaagtTTGGCAGGGAGATGGCCTTCCAGAAAAAATGTGTAATCGTTGTGTAACAAGAGCAGAATCTGCTCTGTTATATAGAGAACAATGTCGTGCGGCAGATAGAGCATTAAGACAAGCCCTTTTAAaggtTTCTGGTTTGACTTCGTATGCAACAGTATctagttataaattatatcaacataatcaaaattttgcaTCTATTCAAAATTCCCATAAGACTTTGAAATGTATAGACTGTGGagcaatatatacaaattatcagGAATTCTGTGCTCATAGTAGATCACATTTACCCTTTGTTCAAGACGATATACCTATGCAACACATGCATATAGTAGAATcgcaaaattcatatttaaattttaactttggtCATCTCAGTTCCAATTGTTTAACTAATGAAAATCTTCAGCATGCACAATCATCTTCATTGATTAGATCAAATATGATGCAAATGATTCCAATAAATGAAAATCCTAGTCGTGCAGCATGTGCTCTACATTGTTCCTTATGTAACCGCACATTTACTAATAGAACTCAATTAATAAGTCACAGTATCACTCACAACTCGGAGAACATAGAAGTACCTtgtgataatgaaaatatagatatctGTGAAAATTCTAATCAAATTCCGCAAAATTTAAGTTACGAAAGATCGATTAATTCCGTTGGAAATTCTATTCAGAATTTATCTTATCATAGGTCTACAACGAATGATAACAACGAAATGCAAAATTTAGGTTTTCCCGAAAATATGGATTTAGGAGACGAAGTTCGAGAGGGTAGCCCCCAACGAATACGAAATGCCGCGATTCCTGATTcagaaaattataacataactGATTATCGTGCGATAAGATTTGCGAAAAGTCTCGAGCGTATCGACAATAGGGAGAATATCAATAGATATCAATCATGctcttcaaatttaaattataataagcaACAAATCGAAAACGAGCAACATTCAGAAAATTTACAACATatacagataaaaaaatacaagtgCGAAATATgctctaaatatttttcgcaaaaatcaaaattgttaaCGCATCAATTATCGCACTCTGGTCAACAGCCTTTCAAATGTTCTAATTGCGAGAAAGGATATTCATCGAAGAGCAAATTAAATGCACATATGCGATTACACACGAAAATTAATGTACATTCATGTAAAAtatgtgataaaatattttcgtatccATCTTATTTGCAGGAACATTTAAAAACACACAAAGAGAGTAGCAATAGCGATAtgagaatcgaagaaaacaAAACTTTTGAATGCGTCAGTTGCAAGAAGAAATTCCGtctattgaaaaatcttaaagCTCACGAACGGCTTCATACTGGCAAAGATTTGATGCGATGCGAAATATGTGATAAAACATTTAGTCGTAATTACAACTTAAAGATTCATTTACGAACGCACAAAACGACGAAACCGCACAAGTGTGAATATTGCAATAAATGTTTCGTTCAGAAAGGTAACCTTGCGGAACACATAAGAATTCATACAAAGATAAAACCTTTTGAATGTAAAATATGTGGGAAGCATTTCTCACAGTCGAGTCACTTGAAAAATCACGAGGCTTCCCATACAACTGTTAGGCAACATCAGTGTCGATTGTGTGGAAAACGATTTAAATTAGCTAATCATTTGAAAAGACATTTGATTTTACACAATGGTGCAAAGTCATACAAATGTCATCAATGTAATCAATTGTTTTCACAAGCATTTAGTCTTACGAGACATTTGAAAAGACACGATTCTCACGGTTAA
Protein Sequence: MFIVTKEIDSENIGKLCRTCLREDGDKMVCLFVGPAESSLAAKLRSLSCLEVWQGDGLPEKMCNRCVTRAESALLYREQCRAADRALRQALLKVSGLTSYATVSSYKLYQHNQNFASIQNSHKTLKCIDCGAIYTNYQEFCAHSRSHLPFVQDDIPMQHMHIVESQNSYLNFNFGHLSSNCLTNENLQHAQSSSLIRSNMMQMIPINENPSRAACALHCSLCNRTFTNRTQLISHSITHNSENIEVPCDNENIDICENSNQIPQNLSYERSINSVGNSIQNLSYHRSTTNDNNEMQNLGFPENMDLGDEVREGSPQRIRNAAIPDSENYNITDYRAIRFAKSLERIDNRENINRYQSCSSNLNYNKQQIENEQHSENLQHIQIKKYKCEICSKYFSQKSKLLTHQLSHSGQQPFKCSNCEKGYSSKSKLNAHMRLHTKINVHSCKICDKIFSYPSYLQEHLKTHKESSNSDMRIEENKTFECVSCKKKFRLLKNLKAHERLHTGKDLMRCEICDKTFSRNYNLKIHLRTHKTTKPHKCEYCNKCFVQKGNLAEHIRIHTKIKPFECKICGKHFSQSSHLKNHEASHTTVRQHQCRLCGKRFKLANHLKRHLILHNGAKSYKCHQCNQLFSQAFSLTRHLKRHDSHG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539757;
90% Identity: iTF_00140736;
80% Identity: -