Basic Information

Insect: Apis laboriosa
Gene Symbol: ZNF496
Assembly: GCA_014066325.1
Location: JACEOM010004374.1:4360981-4363370[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 7.3e-06 0.0014 20.0 3.2 1 23 344 366 344 366 0.98

2 7 9e-07 0.00017 22.8 1.1 1 23 372 395 372 395 0.95

3 7 1.1e-05 0.0021 19.4 1.1 1 23 401 423 401 423 0.99

4 7 1.6e-05 0.003 18.9 0.9 1 23 429 451 429 451 0.96

5 7 5.2e-05 0.01 17.3 3.1 1 23 457 479 457 479 0.97

6 7 3.8e-05 0.0072 17.7 0.5 3 23 487 507 485 507 0.97

7 7 4.1e-06 0.00077 20.8 0.6 1 23 513 536 513 536 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	7.3e-06	0.0014	20.0	3.2	1	23	344	366	344	366	0.98
2	7	9e-07	0.00017	22.8	1.1	1	23	372	395	372	395	0.95
3	7	1.1e-05	0.0021	19.4	1.1	1	23	401	423	401	423	0.99
4	7	1.6e-05	0.003	18.9	0.9	1	23	429	451	429	451	0.96
5	7	5.2e-05	0.01	17.3	3.1	1	23	457	479	457	479	0.97
6	7	3.8e-05	0.0072	17.7	0.5	3	23	487	507	485	507	0.97
7	7	4.1e-06	0.00077	20.8	0.6	1	23	513	536	513	536	0.97

Sequence Information

Coding Sequence: ATGGAATCTGAAAATCCTGTTATATTAGAACCATGTGAAGAACATTCAATCTTAATTCAAACTGTAAAGAATATGGTTAATGAAAATACACGTACTGAATTAGAAAGTGAGGAAGAAGGATTCTTTGTAGTAACTGATGTTCAAACTGAACAGCAAAATGTAATAGAAGTTTCAAATGAAGAATCAACAGTAACTCAATGTAATGAACAATTTTCCTGGTCTAATTTATGCAGAATATGTGCTAATACCAATGATCATTTAATCCCAATATTTGAAGGAGAAGGTTTACAACATGacttatgtaataaaatacataaatatttaccaatatgtATAACTGAAAATGATACACTTCCATTACAATTGTGTTATCACTGTGCTGCTACATTATTAGCATGGCATGAATTATTAGAAGGATGTTTGAGTGCAGAAAGAAGATTATTAGAGATGCAAGATGCTTTACAAGAAAAAcagAGAACAGAAGAATTGGAAACTTCTACACAAGATACAACatctatatctaatataacaGAATCGGttCATCAGCAACAAGAAATTGTGAAAGATGAAGTTTCAAGAGATTTAGCTGTTACTGGTAATGATTCAGACagGTCCAGTAATATGCGAACACCATTTAGAGTGTTCCTAGATATGCAGAATGTATTTTGGAAGCCATACAGAAAAAAGTTCCAGTTGCAAGAAAGAAAGCCTGCAGATAGTGGAGATTGCGATTCGGTATGGATTACTGTCATGAATTCAACACTTGATCAACCTAGTATAATGTCTGATCAACTACAAGACAACAatgatattattgtaaaagaagaactttctcaaatatatagttcaaataatttagaaaaattaaaattacataatgaaacatataaaCCAAcagattctttaaatataaaaaataaaaataaaaaattaaaaggaaaatgtaaaatttgttcTAGTAATACAAAAGAGTTAAAGGATTCTTGTGAACATATGAAGaacaaaactattattaatgttcAAGAATCTTATCAATGTATTGAATGTGGAAAATGTTTTAAGTTAAAAGACTCCTTTCTCAGACACATGAGAATACATACAGACGAAAGGCCGTTTACTTGTCATGTGTGTGGAAAACAATTTAGAGATTCTGGTGGTCTTTCTAGGCATTTAAAAGATGTACAtgcaaaactaaaaaattttacttgcgATATATGTAGCAAATCTTTCGCATCAAAAGCTACGAGAGAAGATCACCGACGAACACATACTGGAGAAAGACCTTACATATGTGATTCATGtggaaaaacatttaaatcaaaagcttctttatatattcatagtaAATTGCACACAGATGAATTTCCACATCCATGCACTTattgtaataagaaatttcgTAGAAGGCAGGAAATGTTGGCTCATGTAACTACTCATacaggagaaaaaaattatggttGTGACGTGTGTTCGAAAAGATTTCGAGTAAAATCAGAACTTGTTAGACATAAACTAATTCACTCTGAAACAAAACCCTTTATTTGTGTAGAATGTGGACTTGCTTTTCGACAAAAAcgttatttgaataatcatattaaaagcAGACATATTGAAACTTTACGAGCATGctaa
Protein Sequence: MESENPVILEPCEEHSILIQTVKNMVNENTRTELESEEEGFFVVTDVQTEQQNVIEVSNEESTVTQCNEQFSWSNLCRICANTNDHLIPIFEGEGLQHDLCNKIHKYLPICITENDTLPLQLCYHCAATLLAWHELLEGCLSAERRLLEMQDALQEKQRTEELETSTQDTTSISNITESVHQQQEIVKDEVSRDLAVTGNDSDRSSNMRTPFRVFLDMQNVFWKPYRKKFQLQERKPADSGDCDSVWITVMNSTLDQPSIMSDQLQDNNDIIVKEELSQIYSSNNLEKLKLHNETYKPTDSLNIKNKNKKLKGKCKICSSNTKELKDSCEHMKNKTIINVQESYQCIECGKCFKLKDSFLRHMRIHTDERPFTCHVCGKQFRDSGGLSRHLKDVHAKLKNFTCDICSKSFASKATREDHRRTHTGERPYICDSCGKTFKSKASLYIHSKLHTDEFPHPCTYCNKKFRRRQEMLAHVTTHTGEKNYGCDVCSKRFRVKSELVRHKLIHSETKPFICVECGLAFRQKRYLNNHIKSRHIETLRAC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00140789;
90% Identity: iTF_00142643;
80% Identity: -