Alab004869.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis laboriosa
Gene Symbol
-
Assembly
GCA_014066325.1
Location
JACEOM010000010.1:394058-397247[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.25 48 5.7 4.1 1 15 205 219 205 223 0.84
2 8 3.8e-05 0.0072 17.7 4.4 1 23 233 255 233 255 0.99
3 8 9e-07 0.00017 22.8 1.5 1 23 261 283 261 283 0.98
4 8 9.7e-06 0.0018 19.6 3.6 1 23 288 310 288 310 0.97
5 8 1.5e-06 0.00028 22.1 3.7 1 23 316 338 316 338 0.99
6 8 6.7e-07 0.00013 23.2 1.9 1 23 344 366 344 366 0.99
7 8 6.7e-05 0.013 16.9 2.2 1 23 372 394 372 394 0.97
8 8 6.6e-06 0.0012 20.1 8.9 1 23 400 422 400 423 0.96

Sequence Information

Coding Sequence
atgaTGAACAAAGTATGTCCAAGTTGtagacaaataataaatacatcgcGTTCAAGACTTGTAAAAGATAGTTGTGGTCATATTAAATGTCGTATGTGTTTAATATATGAAGAACAAGGTTGCAAAATATGTATCAATGAACatagtattgaaaattatgaaaaaaaaatattaaataacgttTCTACTTctgataaaagtaatatatgtaatgaaatattacctttggaattagttattaataaagattccAAACTTAaagcaaataattttgaaccAATTTCtactgattatataaataattatgaattatatcgagaaaatataattaacaaaacaaaagaaataaataaatcttctacagatattaaaaacaatgatacattaaataatttacatatttcaagTAGAGAAACTAATAATGcacttttaaatgtatatccACATTTAAGTAATAATGTAGTAGTAAAATCATcatctaataataaagtaacagAAATTTGCAATGTggaaatcaagacaaaattttccacaaaagaaaaattaaaaaataaatctataaaatgtaCTGATCGTGATCATATTACTATAATACCAGGAATaccagaaaaatataaatgcaatatatgcactaaaatttttcaaaacaagaAAGGAAAATGTTATCATGATGCTTGTATAACAGGTGTTAAACCTTATCAATGTTCTTTTTGTGACAGAAGTTTCATAAAAAGATCACATTTTGAATATCATGAAAGAATTCACAAAGGATATAGACCATATAAGTGTAATCTTTGTGAGAAAGCATTTCCACAACAGAATAAACTTAATAGACATATGTACTCTCATGgAGATAAACAATTTATGTGTTCTAAATGTGATAAAAGATATTCCAAACAagatgatttgaaaaatcatttacatGTACATAATGGAACAACTACATATTCTTGTAAAACTTGTGAAAAAACTTTTAGAATGTTAACTAATTTAAAACGTCATCTAAAAACACATAATaatGAAAGACCATATGTATGTGATCAATGTAATAAAAGctttaaagataaatctttGGTAATTCGTCATAAAAAAACGCATGGAAAAGATAGGCCATTTTCATGTGCACATTGTAATAgagtatttttatctaaaagtgAATTAAGACGTCATTTAACAGTCCATTCAGatgaaaaaccattttcttgtaaatattgtgaaactgtatttagaagaaaagataatttacatCGACACATTAGACATCATCATCCAGAgagtttatcttttaatattaataatgaacaaaATGCAAATCctgaaacaaatacaaaattaacaaaagctaaacaaataaatttaaaacaaaagcaaaagataaaaaagacacAAAAAATGGCTTCTAATCTATTAACAAAAACACCAACTAAGGTATCAGTGGTGTGTATAAGTTCTTGTGACCAAATCAGTTCTAGATTAGATTCAATGGGTAACATTACACCTGTTATAAGAACTACTAATGAAGTCAGTAATGCTGTTTCTGTTATTAATGgaccaattaatattaaaaagctaGATGATAAGTctgatatcaaaaaaaagacatttaCATATACAGAACCAATACCTCTTGCTGAAGcagttgtaataaataaacgtaTTGAAGAAAAGTTATATccacaaaatatatcaaatcacaattattttcttagaaattgtttaaattgtaCAGATAAATCATATCCTACCCTCACAAATCAAATATCTCATACAAATTCTatctaa
Protein Sequence
MMNKVCPSCRQIINTSRSRLVKDSCGHIKCRMCLIYEEQGCKICINEHSIENYEKKILNNVSTSDKSNICNEILPLELVINKDSKLKANNFEPISTDYINNYELYRENIINKTKEINKSSTDIKNNDTLNNLHISSRETNNALLNVYPHLSNNVVVKSSSNNKVTEICNVEIKTKFSTKEKLKNKSIKCTDRDHITIIPGIPEKYKCNICTKIFQNKKGKCYHDACITGVKPYQCSFCDRSFIKRSHFEYHERIHKGYRPYKCNLCEKAFPQQNKLNRHMYSHGDKQFMCSKCDKRYSKQDDLKNHLHVHNGTTTYSCKTCEKTFRMLTNLKRHLKTHNNERPYVCDQCNKSFKDKSLVIRHKKTHGKDRPFSCAHCNRVFLSKSELRRHLTVHSDEKPFSCKYCETVFRRKDNLHRHIRHHHPESLSFNINNEQNANPETNTKLTKAKQINLKQKQKIKKTQKMASNLLTKTPTKVSVVCISSCDQISSRLDSMGNITPVIRTTNEVSNAVSVINGPINIKKLDDKSDIKKKTFTYTEPIPLAEAVVINKRIEEKLYPQNISNHNYFLRNCLNCTDKSYPTLTNQISHTNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01417888;
90% Identity
iTF_00140796;
80% Identity
-