Alab014792.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis laboriosa
Gene Symbol
Kr-h1
Assembly
GCA_014066325.1
Location
JACEOM010004376.1:1314708-1316674[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 1.9e-05 0.0035 18.7 1.6 1 23 61 83 61 83 0.99
2 8 5.8e-08 1.1e-05 26.6 0.5 1 23 91 113 91 113 0.99
3 8 1.4e-07 2.6e-05 25.4 1.2 1 23 119 141 119 141 0.99
4 8 1.6e-06 0.00031 22.0 3.1 1 23 147 169 147 169 0.99
5 8 1.8e-07 3.4e-05 25.1 1.8 1 23 175 197 175 197 0.98
6 8 0.00014 0.026 16.0 3.0 1 23 203 225 203 225 0.99
7 8 3.3e-05 0.0063 17.9 0.7 1 23 231 253 231 253 0.95
8 8 5.5e-05 0.011 17.2 3.3 1 23 259 281 259 281 0.99

Sequence Information

Coding Sequence
ATGGTGggttattatcaaataaaacaaattacaaattccaCAACGATGTCGGTCAAGAATGAAATATCGACTGTGGAACCAGTAGATCCTGTGAAAAGTCTCGTATGTAGTCCGGATTTAAGTGTATTCACTTCACCGGCATGTGGTTCTGAAAcattaacaaatattgaaGAGAAGACATACCAGTGTTTGCTGTGTCAGAAAGCCTTTgatcaaaagaatttatatcagAGCCATTTGCGCTCACACGGTAAAGAAGGTGACGATCCATACCGATGCAATATTTGCGGGAAAACTTTTGCGGTACCTGCGCGACTGACTAGACATTATCGTACACACACTGGTGAAAAACCGTATCAATGCGAATATTGTAGTAAATCGTTTTCCgtaaaagagaatttaagCGTTCATCGTCGTATACATACAAAAGAACGGCCTTACAAGTGTGACGTGTGCGAACGCGCGTTTGAACATAGTGGTAAACTACATCGGCATATGCGAATTCACACCGGAGAACGGCCTCATAAGTGTACTGTCTGTTCAAAAACGTTCATTCAAAGCGGACAATTAGTAATTCATATGCGCACGCATACCGGAGAAAAACCATACGTTTGCAAAGCATGTGGCAAGGGATTCACTTGCTCAAAGCAATTGAAGGTACATACGCGTACGCATACCGGAGAGAAACCATATACTTGTGACATTTGCGGGAAATCCTTTGGTTATAATCATGTATTAAAGTTACATCaggtTGCCCATTATGGTGAAAAAGTTTATAAGTGTACATTATGTCATGAAACTTTTGGTTCAAAGAAAACAATGGAGTTACATATTAAAACTCATTCAGATTCATCAGTTGTTGGTTCTCCTCGGGATTCGCCAATTGAGCCAGAAATTGAAATCTCACAGAATAGTGTAAGCACTGGCAGTGACAAGGAAAATCACAAGACTGAAGAGCCAAACGATGAAGTTGCTACTTACGATAACACTCCACGTGATTTTccttattatatgtattccaGAGAGCAGTATTCACAATCACATCTCATATCTAGTGAAAATAGAGACTTTCAAACAACACCTACTGTCTCTGTTGAACAGcctcatttatttttgtatccaGAAGTTTCTTCAACATATACTGGTTTTGGAATTCAAAGTACTGATTTTGTTGGTGATTGTTCATCTCTTCTCAATTTGCCAGGAAATGATGCTCGTAGAAGAGTTGAGGCTGCGCTGGAAGCAGTTGAAGAAGAAAGGCAAAGAGAATATGGAATCAGAGTTGAAAGAGATCCAATTCTAACTCCTCCAAGTAGCAATCCTGTGAGTCCTGTACCTTCGCCAGATCCTCTTGATTTGGCAATTCCTGTACGAGAAACATTAATTCTCCCTCCAAGAAAACGGTGTAAAATGATATTAGAATCCATGGAAATTGAAAGGAATGGTCTTATTGCCTCTCAAAGACAGAACTCTGTTATTCAATTTGCAAAAGCATCATAG
Protein Sequence
MVGYYQIKQITNSTTMSVKNEISTVEPVDPVKSLVCSPDLSVFTSPACGSETLTNIEEKTYQCLLCQKAFDQKNLYQSHLRSHGKEGDDPYRCNICGKTFAVPARLTRHYRTHTGEKPYQCEYCSKSFSVKENLSVHRRIHTKERPYKCDVCERAFEHSGKLHRHMRIHTGERPHKCTVCSKTFIQSGQLVIHMRTHTGEKPYVCKACGKGFTCSKQLKVHTRTHTGEKPYTCDICGKSFGYNHVLKLHQVAHYGEKVYKCTLCHETFGSKKTMELHIKTHSDSSVVGSPRDSPIEPEIEISQNSVSTGSDKENHKTEEPNDEVATYDNTPRDFPYYMYSREQYSQSHLISSENRDFQTTPTVSVEQPHLFLYPEVSSTYTGFGIQSTDFVGDCSSLLNLPGNDARRRVEAALEAVEEERQREYGIRVERDPILTPPSSNPVSPVPSPDPLDLAIPVRETLILPPRKRCKMILESMEIERNGLIASQRQNSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00140751; iTF_01069133; iTF_01070532; iTF_01065735; iTF_01068455; iTF_01069836; iTF_01424532; iTF_00684313; iTF_01067097; iTF_01066428; iTF_01067772; iTF_00684928; iTF_01418497; iTF_00220739; iTF_00229507; iTF_00224037; iTF_00227429; iTF_00228838; iTF_00219271; iTF_00221417; iTF_00215179; iTF_00224715; iTF_00219952; iTF_00217233; iTF_00225393; iTF_00226069; iTF_00222678; iTF_00218585; iTF_00223353; iTF_00215867; iTF_00226751; iTF_00228128; iTF_01419140; iTF_01419786; iTF_01421070; iTF_00231473; iTF_00961987; iTF_01123213; iTF_00962671; iTF_01122609; iTF_00963352; iTF_00964633; iTF_00963994; iTF_00118169; iTF_00761125; iTF_00864799; iTF_00865487; iTF_01417863; iTF_00734090; iTF_00303281; iTF_00862737; iTF_00983122; iTF_00233387; iTF_00230189; iTF_00982447; iTF_00216558; iTF_01071154; iTF_00085621; iTF_00089025; iTF_00084745; iTF_00086576; iTF_00087382; iTF_01169335; iTF_00088252; iTF_00625659; iTF_00873942; iTF_01539767; iTF_00763385; iTF_00024769; iTF_00866855; iTF_00861354; iTF_00183435; iTF_00966164; iTF_00184095; iTF_00762714; iTF_00866170; iTF_00863421; iTF_00860578; iTF_00864126; iTF_00361087; iTF_00360379;
90% Identity
iTF_00140751; iTF_00734090; iTF_00220739; iTF_00229507; iTF_00224037; iTF_00227429; iTF_00228838; iTF_00219271; iTF_01417863; iTF_00221417; iTF_00215179; iTF_00224715; iTF_00233387; iTF_00230189; iTF_00982447; iTF_00219952; iTF_00217233; iTF_00225393; iTF_00231473; iTF_00226069; iTF_00222678; iTF_00218585; iTF_00223353; iTF_00215867; iTF_00226751; iTF_00228128; iTF_00216558; iTF_00983122;
80% Identity
-