Aaln084040.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphrophora alni
Gene Symbol
polg2
Assembly
GCA_963513935.1
Location
OY740777.1:40703566-40744088[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.16 54 6.8 5.0 1 23 489 513 489 513 0.93
2 14 4.9 1.7e+03 2.1 10.4 2 23 556 577 555 577 0.96
3 14 2.5e-05 0.0083 18.8 2.9 1 23 583 605 583 605 0.98
4 14 6.8e-05 0.023 17.4 3.2 1 23 611 633 611 633 0.98
5 14 6.4e-06 0.0022 20.7 1.4 1 23 639 661 639 661 0.99
6 14 3.7e-05 0.012 18.3 1.9 1 23 667 689 667 689 0.99
7 14 0.00059 0.2 14.5 0.6 1 23 695 717 695 717 0.99
8 14 3e-06 0.001 21.7 0.9 1 23 723 745 723 745 0.98
9 14 0.0018 0.61 12.9 2.9 1 23 751 773 751 773 0.99
10 14 3.1e-05 0.01 18.5 1.4 1 23 779 801 779 801 0.99
11 14 0.0012 0.41 13.5 6.0 1 23 807 829 807 829 0.99
12 14 1.1e-05 0.0038 19.9 3.8 1 23 835 857 835 857 0.99
13 14 0.0082 2.8 10.9 5.2 1 23 863 885 863 885 0.99
14 14 3.4e-05 0.011 18.4 0.8 1 23 891 913 891 913 0.99

Sequence Information

Coding Sequence
ATGACCAatggttttcaaaaaatattagaaCTAAGTGAGTTACATGGATATATCAAACCTATCATCATCAACAATATTATCAATCACTTCAAGTATGGACCTCTAGGTGAACTGTTGGCGCAGAATATACGTAATGAATGGATTTATAGCAATGTGACCAATAGGGAAGAGAATGTATTTTTGTATCATGATTCTCGATCAAATGGGAAATCTATTATACATTGTAAAGATGCTTTCAAAAATGCTCGTGAGATAAGTCAAGGCTATTTACCTTTTGGTCTTGCAACTACTCGTGACGACCAAGTTGAAGTACCAGTTCCTAACGTAGGCCTACAATATTTTCATCCCACTTGCTCCCATTGTTTGAGATACATGGCGTTTACATCACCAAGCCAAGGACAACAGTTCTTCTACAGATGGCAGCAACAAAGGAAGATGTGGTGGAGGAAgTTTTCAGCAGATCCAGGAAGATTTTCTTTCTCTGAAGTACGTAGTGTTACGGATGAAAAAGAGTTGGAAAGTATGAACATCTCTGCCAGCTTTCCATGGGGCGATGAAACTTTAGAAACTATAATTAATCATGGGACAGTACCATTTGATTCTTTAAAGAATTCGGAAAAAACATTCTTTGAAgcgAGGGATGGTCAAAAGAAGATACTGCCATACGTTATCGAGAGTGTATGTACCGAAGCTACAGCTGTAATGGCGTTTTTGTGTGATGCTTACTGTGAACCTTCAGTCATGGGTACTACTAGGAAACTGTTAAGGTTACATCGTAAACTGGCTCCTTACAAGACAACGTTTGTTGCTGCATCTACAAgttatagTGTAAGAGATGAACTTCGGCTATTGGCTACATTCTTGAATCAAGGTTTACGAAAAGCAGGGATCTCTACATTATTACCAGGTCCTGGATTGGCCAAAAAGTCATTGGAATCCCAGCTTGCTCTGAATGACTGCCTCGGAATTccctttacaattgtattatcgcAAACGACACTTGACAACGGTGTCGTTGGGATTAGAAGCAGAGAAACTACTCTAGAAaacATAATCATGGAAAATCTGTTGgataatattaaacaagaaaatgtggatatagaaataaaagaagaagaagaaatttgttTCGAGTCAGTAGAAATAGGAAGTTACTTGATTGATGGAATCAAAGAAGAGAGTGTAATAAGTACCGGTAATGAAACGGAGAAAGAAAATGACAGTTTGGACGTTGACAGAAACGAAGATATTGATGATATACAGTCAAGCAAGATAATGGAATTCATCCATGTGAACACTGAAGAGGAAGTAGAAGACAACTGGACTGTGCCTGTAGAGCATGAAACAGACCCATTGGCTTTGTTCCCTGCTGTAAACACTAAAGTTGAGACTCAATCTTCAGACGAGGACAACACAACCACAAAAAATGTCTCTCCTAGCACCTCACAAGATAGATATTTGCTGTTTGTATGTGGAAAGTGTGGCAGTAAGTTCAGTTCGTATGATGAGCATCGTAAGCACATAAAGACTTGTTCACATTTAAGAAATTCAACTTTACACATAAACTGTCATTGGAAGCAAAAGCTGTCTGAACCTACTGAATGTTCTGATTTCCTACATTACGATAAAAGACACACAAGAGTGCATACAGAAAACAACCCATGTAAGTGCTCACAGTGTTGTTATTCTAGTAAAGAACAAAGTcattttaaaagacatttaaaagtGCATTCAGGTGAAATATCATATAAATGCACAGAATGTGATTATTCATGTATAGAACAAAGTTAccttaaaaaacatataaaaggtCATGCAGAAGAAAAGCCATTTAAGTGCTCACAATGTAATTATTCCACTATAGAACAAAGTCACCTTAAAAGACACATAAAAGGGCATACAGGGGAAAAACCATACAAATGCACAGAATGTGATTATGCCTCTGTAGAGCAAAGCCACCTTAAAAGGCATATAAAAGTGCATACAGGGGAAAGACCATTCAAATGCACTGAATGTGATTATTCTGCTATAGAGCAAAGTCAccttaaaaaacacttaaaagtgCATATGcctaaaagaatatataaatgcACAGTGTGTGTTTTTTCTGCTATGAAAGAAAGTAATCTTAGAAGACATATGAATGTACATATAACTGATAAACCATACAAATGCACAGAGTGTGATTACACCACTATAGAACAAAGTAATCTTAAAAGACACATAAAAGGGCATACAAGGGAAAAACCTTACAAATGCACAGAATGTGATTATTCTGCTCTAGAACAAAGTCACTTTAAAAGACACATGAAAGTGCATACAGGGGAAAAACCATTCAAATGCACAGACTGTGAGTATTCCGCTATAGAACATAGTAATCTTAAAAGACACATAAGAGTGCACACAGGGGAAAAACCATTCAAATGCACAGAATGTGATTATTCTGCTATAGACCACTGTCATCTTAAAAGACACATAAAAGTGCATTCAGAGGAAAAACCGTTCAAATGCACAAAGTGTGATTATTCTTCTGCAAACCATAGTAACCttaaaaatcacataaaaatgCATACAgGGGAGAAACCATACAAATGCACAGAGTGTGATTATTGTACTTTAAAACCATGTGATCTTAAAAGGCACCTAAGAGTACACACAGGGGAAAGACCATATAAATGTACAGAATGTGACTATTCTGCCAAGGAACGACGTAATCTTATTAGACATTTAAAAGTACATACTAGAGAAAATCCATGTAAATAG
Protein Sequence
MTNGFQKILELSELHGYIKPIIINNIINHFKYGPLGELLAQNIRNEWIYSNVTNREENVFLYHDSRSNGKSIIHCKDAFKNAREISQGYLPFGLATTRDDQVEVPVPNVGLQYFHPTCSHCLRYMAFTSPSQGQQFFYRWQQQRKMWWRKFSADPGRFSFSEVRSVTDEKELESMNISASFPWGDETLETIINHGTVPFDSLKNSEKTFFEARDGQKKILPYVIESVCTEATAVMAFLCDAYCEPSVMGTTRKLLRLHRKLAPYKTTFVAASTSYSVRDELRLLATFLNQGLRKAGISTLLPGPGLAKKSLESQLALNDCLGIPFTIVLSQTTLDNGVVGIRSRETTLENIIMENLLDNIKQENVDIEIKEEEEICFESVEIGSYLIDGIKEESVISTGNETEKENDSLDVDRNEDIDDIQSSKIMEFIHVNTEEEVEDNWTVPVEHETDPLALFPAVNTKVETQSSDEDNTTTKNVSPSTSQDRYLLFVCGKCGSKFSSYDEHRKHIKTCSHLRNSTLHINCHWKQKLSEPTECSDFLHYDKRHTRVHTENNPCKCSQCCYSSKEQSHFKRHLKVHSGEISYKCTECDYSCIEQSYLKKHIKGHAEEKPFKCSQCNYSTIEQSHLKRHIKGHTGEKPYKCTECDYASVEQSHLKRHIKVHTGERPFKCTECDYSAIEQSHLKKHLKVHMPKRIYKCTVCVFSAMKESNLRRHMNVHITDKPYKCTECDYTTIEQSNLKRHIKGHTREKPYKCTECDYSALEQSHFKRHMKVHTGEKPFKCTDCEYSAIEHSNLKRHIRVHTGEKPFKCTECDYSAIDHCHLKRHIKVHSEEKPFKCTKCDYSSANHSNLKNHIKMHTGEKPYKCTECDYCTLKPCDLKRHLRVHTGERPYKCTECDYSAKERRNLIRHLKVHTRENPCK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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