Basic Information

Insect: Aphodius sticticus
Gene Symbol: ZEB2
Assembly: GCA_963966075.1
Location: OZ014510.1:23993408-23996238[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 9.9e-05 0.0076 18.1 0.3 1 23 162 184 162 184 0.99

2 12 0.59 45 6.2 4.8 3 23 190 211 189 211 0.94

3 12 0.01 0.79 11.7 4.9 1 23 268 290 268 290 0.99

4 12 0.0016 0.12 14.3 1.4 3 23 296 317 295 317 0.97

5 12 9.4e-05 0.0072 18.1 0.5 1 23 371 393 371 393 0.97

6 12 0.094 7.2 8.7 0.7 3 23 400 421 398 421 0.92

7 12 0.00034 0.026 16.4 1.0 1 23 434 456 434 456 0.99

8 12 1.5e-05 0.0012 20.6 0.2 1 23 462 485 462 485 0.98

9 12 7e-06 0.00053 21.7 0.6 1 23 491 514 491 514 0.95

10 12 8.8e-06 0.00067 21.4 1.4 1 23 523 545 523 545 0.97

11 12 3.1e-05 0.0024 19.7 1.7 1 23 551 573 551 573 0.97

12 12 5e-06 0.00039 22.1 3.4 1 23 579 601 579 601 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	9.9e-05	0.0076	18.1	0.3	1	23	162	184	162	184	0.99
2	12	0.59	45	6.2	4.8	3	23	190	211	189	211	0.94
3	12	0.01	0.79	11.7	4.9	1	23	268	290	268	290	0.99
4	12	0.0016	0.12	14.3	1.4	3	23	296	317	295	317	0.97
5	12	9.4e-05	0.0072	18.1	0.5	1	23	371	393	371	393	0.97
6	12	0.094	7.2	8.7	0.7	3	23	400	421	398	421	0.92
7	12	0.00034	0.026	16.4	1.0	1	23	434	456	434	456	0.99
8	12	1.5e-05	0.0012	20.6	0.2	1	23	462	485	462	485	0.98
9	12	7e-06	0.00053	21.7	0.6	1	23	491	514	491	514	0.95
10	12	8.8e-06	0.00067	21.4	1.4	1	23	523	545	523	545	0.97
11	12	3.1e-05	0.0024	19.7	1.7	1	23	551	573	551	573	0.97
12	12	5e-06	0.00039	22.1	3.4	1	23	579	601	579	601	0.98

Sequence Information

Coding Sequence: ATGGCTTCTGTGTGCCGATTGTGTTTGAGTTCTGATTCAAACCACTACGAAACTATAGGAGCAATAGAAGAAAAATATTTCCAGCTAATACTACCAGAAATTGATATTCAGTTGGTACAGTCACCAACATTCTGTCAGAGTTGTATTGAATTACTACAGACCAGCTATTCGTTTAAGAGTAACTGCATTGAAAcagagaaaaaattaaaatcgtacGCTTCAAACTCCAATGAGGGAAAATTGTTGCTGAGCAAAGTACTTCAAAGTAATTTTTGGGAAAAGAATCGGATACTGTCCGGCAGAAATGACGCAGAGACTCAATTAAATAATGATATTAAAGTTGAATATGATAATCACAGCTTTGAGTGTGATTTAGATCTGGCAGGACAGGATTTACAAAGTTGTCCTGAAATTGAGACAAAACCTGATGAAAATCAACAAGGCAAGAAACACTTGGATACGATAATGGATTACAAAAAACCTTTCCAATGTGAAGACTGTGGTTCTTCTTTCTATAAAAAGGCACTCTTAGTGGGTCATATCAAGAGACACTATGAACACCCACACTGTTTCACCTGCGATAAAATATTCTACAACCGTTATGGGTTGAAGTGCCATCTATTAAAGGTACATAAGATTGAAATGAGCGAGGAGCATAAAGAGAAActttacacaataaaattaGATAGTGCTAAATTGAATGATAGTTTACAGAAACATTTAAAACTATATAAGAGCGTAGTAGATGTTAAAGGAGGAGAATATACAGATTCAGATGACGAAGGAATAGATGAAAGGCCATACAAATGCCACATATGTCAGAAAGGTTATCACATGAAAAAATCTTTCCTTGGACATATTCGAATTCATTTTACCAAATCCGATTGCAAACTCTGCAGTAAACAATTTAATAACATAACCATGTTAAAGCGCCATCTAACGACTGCACACCAAATTGACGTGGGCGACAACATAAGTTGGCGTAACCACATCACCGTCATAGTCGATATCCCGGAGATGGAAAAAGCTATACAAGAACACAGCAAGCTGGAAGAAATGGATGATAAAAATGAATTAGAGGTAGTTGAAAACTTTTCAGTTACTTCTGAATACATTTGCGAATCCTGTGGAAAACAGTTTAAGGCCAAGGCATCATTGAACAGACATAAATTAATACACACCAACAAAACAACAATCTGTGCTTACTGCCAAAAAGGATTTCTAACTAAAGCGACACTCGAAATGCATATTTCTGCGTGCCACCCAGATATTTGTAGTAAACGCACGCTAGACCGTAATTTTACTTGTGATACTTGCGGGTTTTcaacaatttataaatatagGCTAATCGAGCATATACGTACACACACTGGTGAAAAGCCTTATAAGTGTGTCTTGTGTGATAAAGGCTTTGCTCAAAGTAGCTCATTGGGTTGGCATAAGCGAACAGTGCATTCAACAGAGCGATTATTTACCTGCGAATATTGTAGTAAATCATTCAATGTAAATGGATCTTTGAAAAAGCACATTCTAGAAGTGCACATGGTTCATAAAATTGAGAAGAAATTCATTTGCAGTTACTGCGGGAAGAAGTATCGATTGCAAAGCCAGTTGAACTCCCATTTGAAGTGGCATACGTCAGATAAGCAGTTCAGCTGTGATATATGTGGAAAAGAGTTTGTAGATAGACACTCGGTTAAGAAGCATAGAGTAACCCATTTTGCGGAGAAGAAACACAAGTGTGAAATTTGTGGTAAAGGATTCCATCAGAAATCTAATATCAAGATACATATGAAGGTCCATTCCAGAGCTCCATAA
Protein Sequence: MASVCRLCLSSDSNHYETIGAIEEKYFQLILPEIDIQLVQSPTFCQSCIELLQTSYSFKSNCIETEKKLKSYASNSNEGKLLLSKVLQSNFWEKNRILSGRNDAETQLNNDIKVEYDNHSFECDLDLAGQDLQSCPEIETKPDENQQGKKHLDTIMDYKKPFQCEDCGSSFYKKALLVGHIKRHYEHPHCFTCDKIFYNRYGLKCHLLKVHKIEMSEEHKEKLYTIKLDSAKLNDSLQKHLKLYKSVVDVKGGEYTDSDDEGIDERPYKCHICQKGYHMKKSFLGHIRIHFTKSDCKLCSKQFNNITMLKRHLTTAHQIDVGDNISWRNHITVIVDIPEMEKAIQEHSKLEEMDDKNELEVVENFSVTSEYICESCGKQFKAKASLNRHKLIHTNKTTICAYCQKGFLTKATLEMHISACHPDICSKRTLDRNFTCDTCGFSTIYKYRLIEHIRTHTGEKPYKCVLCDKGFAQSSSLGWHKRTVHSTERLFTCEYCSKSFNVNGSLKKHILEVHMVHKIEKKFICSYCGKKYRLQSQLNSHLKWHTSDKQFSCDICGKEFVDRHSVKKHRVTHFAEKKHKCEICGKGFHQKSNIKIHMKVHSRAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00981458;
90% Identity: iTF_00981458;
80% Identity: -