Basic Information

Gene Symbol
-
Assembly
GCA_963966075.1
Location
OZ014507.1:16687422-16708928[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8.5e-05 0.0065 18.3 0.2 1 23 90 112 90 112 0.98
2 15 6.9 5.3e+02 2.8 0.1 1 8 159 166 159 170 0.88
3 15 0.00064 0.049 15.5 0.2 1 23 202 224 202 224 0.98
4 15 0.00064 0.049 15.5 0.2 1 23 271 293 271 293 0.98
5 15 5.9e-05 0.0045 18.8 0.0 1 23 340 362 340 362 0.99
6 15 0.0076 0.58 12.1 0.7 1 23 496 518 496 518 0.98
7 15 0.0027 0.21 13.5 1.2 3 23 533 553 531 553 0.92
8 15 0.00011 0.0082 18.0 1.3 1 23 559 581 559 581 0.99
9 15 1.6e-05 0.0012 20.6 2.3 1 23 587 609 587 609 0.99
10 15 1.1e-05 0.00086 21.0 0.3 1 23 615 637 615 637 0.99
11 15 0.0059 0.45 12.5 0.7 1 23 643 665 643 665 0.98
12 15 1.6e-05 0.0012 20.6 0.2 1 23 671 693 671 693 0.99
13 15 0.00076 0.058 15.3 5.3 1 23 699 721 699 721 0.99
14 15 1.2e-05 0.0009 21.0 0.3 1 23 727 749 727 749 0.99
15 15 0.13 10 8.2 6.3 1 23 755 777 755 777 0.99

Sequence Information

Coding Sequence
ATGTCTACGACTGAGCAATATCCGTCTATAAAATGTGAAACAACCGATGATGCAAGTAACGACTGCAAGCATGACGAACAAAAACCTGCTCAAAATTCTGCCGATACGTGTGCAGAAGGAACCAATCTTAGTCATGAACTATTTGAAGACACATTTCGGAGCCCAGTAGAGACaatttacATGAAAAATGAAGAAGTGGGAACCAGTGAAACTACCATTTTTGGACAACCTAATGAAAGTCTTAAGACGGAAGCTCCTGATGAACTTTTCAAATGCAGCGACTGTGGCTACGCAGCTGCACAGTCATCACAACTAGAAGatcataagaaaatgcattacCAAACACAGTCAAGCAAGCAGTCCAGTGATTTGCACTTGGGAATTTACATAAAATGTGAAGAATTGGAAACCACTGAAACTACTATTTCCGGACAACCTAATGAAAGTCTTAAGACGGAAGCTCCTGAGGAACTATTCAAATGCGGGGACTGTGGCTACGCAGCTGCACAaatttaCATAAAATGTGAAGAATTGGAACCCACTGAAACAACTTTTGCTGAACAACCTAATGAAAGTCTTAAGACGGAAGCTCCAGAGGACCTATTCAAATGCAGCGAGTGCGGCTACGCAGCTGCACAATCAACACAACTAGAAGAACATAAGAAAATACATTACCAAATACAGTCAAACAAGCAGTCCAGTGACATGCACTTGGGAATTTACATAAAATGTGAAGAATTGGAACCCACTGAAACAACTTTTGCCGAACAACCTAATGAATGTCTTAAGACGGAAGCTCCAGAGGACCTATTCAAATGCAGCGAGTGTGGCTACGCAGCTGCACAATCAACACAACTAGAAGAACATAAGAAAATACATTACCAAATACAGTCAAGCAAGCAGTCCAGTGACATGCACTTGGGAATTTACATAAAATGTGAAGAATTGGAACCCACTGAAACCACTTTTGCCGAACAACCTAATGAAAATCTTAAGACGGAAGCTCCAGAGGACCTATTCAAATGCAGCGAGTGTGGCTACGCAGCTGCACAACCAACACAACTAGAAGAACATATGAAAATACATTACCAAATACAGTCAAGCAAGCAGTCCAGCGACGTGCACTTGGGAATTTACATAAAATGTGAAGAATTGGAAACCAGTGAAACCAGCAAGCAGTCCAGTGACGTGGTCTTGGGATGCTCTGCAGAagggaaaccatttaaatgcaccctatGCAATTTGAAATATGAATCGTGTGAGGAGAAGATTCAGAGCACAGAATTGCTTGACGAACATCAACCAATTGAACCGATTTTCGTAAAAGTAGAAGAATTGGAATTCACGGACAGTACTATATCCGGCTACACTACTCCAGCATCCGAACAACCAATCGAACCTTCGTTAGATCTACTTGAGTGTGACAACACAGCTCCTCCATCAACGCAACTTAACCACGTCAACATACATAACCAAGAGACGCCGTATAGCTGCGACATTTGCAACTACACCACCACAGAATCAATATTCCTGACCGCGCATAAACAGAGCCACGCGGTGAGCAAATTACCAGGAGTGCGCAAGAAATCGCTAAATTGCATCATATGCGGCCATTATAGCTCGGACCGTTCCGGTCTGAGAAGACACATACGAACACACACGGGTGTCAAACCGTACAAATGTACCGAATGTGGCTACGCCTGCCTTAGTAACGCCAATCTCGCAACGCACATGAGACGGCATACGGGAGAAAAACCGTTTAAATGTACcctatgtgattatgctagtgcacATAGTAGCGACCTAACCCAGCATATGAggaagcatacaggagagaaaccgttTCAGTGTACCTTATGCGACTATGCTAGTGCAGATCGTTCTGCTTTGAAACGACACATTCAaacgcatactggagagaaaccgTTCAGATGCACATTCTGCGATTATGCTAGTTTGACTAACGCTAACCTTACACGCCATGTACTGACGCATACGAGCGAGAAACCGTTTAAGTGTGGCATGTGCGAATATGCGACTGTGACTAATGCTAACCTCATAACGCATATGAGAactcatacaggagagaaaccgttTAAATGCGCCGAGTGTGATTATTGTACTGCGCACCATGGTGATCTTACACTGCATATGAGGAGGCATACCGGAGAAAAACCGTTTAAGTGTTACATATGTGGGTATACTAGTGCTGGTCGTTCAGCTCTTACGGTGCATATGAGAACTCATACCGGAGAGAAGccttttaaatgcaccttatgcgaATATGCTTGCCTTAGTCATACTAATCTTTCACGGCACATGAAGAAGCATAGATGA
Protein Sequence
MSTTEQYPSIKCETTDDASNDCKHDEQKPAQNSADTCAEGTNLSHELFEDTFRSPVETIYMKNEEVGTSETTIFGQPNESLKTEAPDELFKCSDCGYAAAQSSQLEDHKKMHYQTQSSKQSSDLHLGIYIKCEELETTETTISGQPNESLKTEAPEELFKCGDCGYAAAQIYIKCEELEPTETTFAEQPNESLKTEAPEDLFKCSECGYAAAQSTQLEEHKKIHYQIQSNKQSSDMHLGIYIKCEELEPTETTFAEQPNECLKTEAPEDLFKCSECGYAAAQSTQLEEHKKIHYQIQSSKQSSDMHLGIYIKCEELEPTETTFAEQPNENLKTEAPEDLFKCSECGYAAAQPTQLEEHMKIHYQIQSSKQSSDVHLGIYIKCEELETSETSKQSSDVVLGCSAEGKPFKCTLCNLKYESCEEKIQSTELLDEHQPIEPIFVKVEELEFTDSTISGYTTPASEQPIEPSLDLLECDNTAPPSTQLNHVNIHNQETPYSCDICNYTTTESIFLTAHKQSHAVSKLPGVRKKSLNCIICGHYSSDRSGLRRHIRTHTGVKPYKCTECGYACLSNANLATHMRRHTGEKPFKCTLCDYASAHSSDLTQHMRKHTGEKPFQCTLCDYASADRSALKRHIQTHTGEKPFRCTFCDYASLTNANLTRHVLTHTSEKPFKCGMCEYATVTNANLITHMRTHTGEKPFKCAECDYCTAHHGDLTLHMRRHTGEKPFKCYICGYTSAGRSALTVHMRTHTGEKPFKCTLCEYACLSHTNLSRHMKKHR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-