Agra023657.1
Basic Information
- Insect
- Aphodius granarius
- Gene Symbol
- ZNF296
- Assembly
- GCA_963971325.1
- Location
- OZ020227.1:1564955-1567097[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.0025 0.22 12.9 1.0 2 23 166 187 165 187 0.97 2 18 6.1e-06 0.00052 21.1 1.8 1 23 193 216 193 216 0.97 3 18 0.00012 0.011 17.0 1.4 1 23 225 248 225 248 0.97 4 18 0.0076 0.66 11.4 3.4 1 23 253 276 253 276 0.97 5 18 0.02 1.7 10.1 5.7 1 23 286 309 286 309 0.92 6 18 2e-06 0.00017 22.7 0.8 1 23 317 340 317 340 0.97 7 18 0.17 14 7.2 0.8 3 20 350 367 349 367 0.96 8 18 0.0011 0.091 14.1 3.5 1 23 375 398 375 398 0.96 9 18 0.00032 0.027 15.7 0.4 2 23 406 428 405 428 0.96 10 18 4.3e-06 0.00037 21.6 0.5 1 23 438 460 438 460 0.96 11 18 0.0068 0.58 11.5 1.4 1 23 466 489 466 489 0.92 12 18 0.031 2.7 9.5 0.2 1 23 498 521 498 521 0.92 13 18 2e-05 0.0017 19.5 2.5 1 23 526 548 526 548 0.99 14 18 8.8e-06 0.00076 20.6 0.3 1 23 554 577 554 577 0.97 15 18 1.2e-05 0.001 20.2 0.2 1 23 583 606 583 606 0.94 16 18 0.0096 0.82 11.1 1.1 1 23 615 637 615 637 0.95 17 18 8e-08 6.9e-06 27.1 0.4 1 23 643 665 643 665 0.98 18 18 1.2e-05 0.001 20.3 4.4 1 23 670 692 670 692 0.98
Sequence Information
- Coding Sequence
- ATGTCTGTTTGTCGCCTCTGCTTAAAACTAACACCAGAAGAATTATGCAAAAGAATAACATCGATCAAAGAAGAGCAATTTAGACTTATCCTACCAGAAATTGACCTCACCTCCGTGGAATCACCTGTAATATGCGATCTTTGCGTAAGTTCACTCCAAGACGCTTACAGTTTTAAAGCAGAATGCCTTCGATCAGAAAAGGTCATCAACATCTACAGAGAAGTGCACGGCAACATTAATTTAATCGAAATTCACAAAGTTAATGCAATTAGTTCGAGTGACAATTTGGATGATAAAAGTCATCTATTTATCGGTGATTCCTATGTAAAAGATGAAATTGGAGAAGATAATTTTAATGCAGGAGAAAATGACGGTGAAGAAGACGTAAAGTTAGATATTAAAAAAGAGGATACTAAAATATCAGGTACTAAATCGAATACCACTAGAAAAAAATCCACTAAACGTGGGAAGTCAGAAACATCTGATATAAATCTAACATGCTCCGAGTGCTCGTTAAGTTTTAAAACTACAACTATTTTACAAAGACACCAAGCGACTCACAGCACAGAAAGGAAATTTAGTTGTTcggattgtgataaaaaatttACGGTACGTAGATATTTACAGGAGCACATAAAAAGATTACATTCCCAACTAAATAATCTAAATAAATACGAATGCAAACTATGCGATAAAGTGTTCTATGAAGTATTCAAGCTAAAAAGGCACTACAGAGAAGTTCACGGCGAGAAAAACTTCAAATGCAAACAATGCAATTCAAGTTTTTCAGCTAAACGATACTTAGACTCGCACATGTATAGACGACACATAACTAACACTGAAGACCGAAAGAAATACAAATGTGATAAATGTGCAATTTGTTTTACAACACACCGAAACTTGTTAACACATAATGACCGTAAACATAAAACAAACGAAACTTTGAAATTCACCTGCCCACTTTGCAAACTCACGTTTACAACTTTAGACAATCTCCAAACTCACATTAAACAAGAACACGATAATTCATCAATACAActaaacttttgtaaactttgtgCTAAAGAATTCGACAATTTCGACAAACTAAAAGAACACCAACCCATTTGCCAGGAGAAACAATTCATTTGCGACAAATGCGGGAAACGCTACAAGTGCAAGAGCAATCTCCTCGATCACATAAGTCGATATCACTCCATAAAAAATCACAGTGTAATGTGCCAAACCTGCGGCTTGATATACAAAAACAAAATGTCACTGAACATGCACATCCAAACTCAACATTTAGGGATTCGACGGAAACGTCCAAAATACCCGTGTGATACTTGCAGTAAGAGTTTTTCTCGACCGACGGCTCTCCGCAGACATAAAGTAATCCACCAAGTTCACACGGATTTCCTATGTCCGGTTTGCCAGCAAGGTTTTAATTCGAAATTTTACATGCATAAACACATCAGTGAGATCCATTTTGATAAAAGGGAACTTACGAAATACATCTGCCAACATTGCGACGCCGAATATGATAATATATGGGATTTGAATGCTCACAAATCGGAGACTCATGTAAAAAATCGTTACACTTGTGAAGTTTGTGGCATCACTTGCTCGAAAAAGTCGTTATTGGTGATTCACATGCACACGCATACCGGAGTGAAACCGTATGCGTGTGATGAATGTGATAAGGCTTTTGCACAACGTAATACGTTAATAAGCCATAAAAAGACGGTCCACGGTACTGAAAAACCGTTTTCTTGCACGTATTGTGAGAAAAAGTTTCCTGTGAAAGGGAATTTAATAAAGCACATTGAGGGGGTTCACTTGAGAGATAAATTGGAGAAGAAATTCGTATGTAGTTTTTGCTCGAAGAGCTTCTTAAGAAGGAAGGAACTCATGATGCATACCGCGTGGCATACTGGAGAAAGGAACTATAAATGTACTATTTGTGGTAAGAGTTTTGTAAATAGTGGGGCATTGAGAAGGCACAAGCTTATACACGACGAGAAGAAGCATGAGTGTGAGATTTGCTTGAAGAGATTTCATCAGAAATCTAATTTAAAGATACATATGAAGGTGCATAATAAAGCTTTGTAA
- Protein Sequence
- MSVCRLCLKLTPEELCKRITSIKEEQFRLILPEIDLTSVESPVICDLCVSSLQDAYSFKAECLRSEKVINIYREVHGNINLIEIHKVNAISSSDNLDDKSHLFIGDSYVKDEIGEDNFNAGENDGEEDVKLDIKKEDTKISGTKSNTTRKKSTKRGKSETSDINLTCSECSLSFKTTTILQRHQATHSTERKFSCSDCDKKFTVRRYLQEHIKRLHSQLNNLNKYECKLCDKVFYEVFKLKRHYREVHGEKNFKCKQCNSSFSAKRYLDSHMYRRHITNTEDRKKYKCDKCAICFTTHRNLLTHNDRKHKTNETLKFTCPLCKLTFTTLDNLQTHIKQEHDNSSIQLNFCKLCAKEFDNFDKLKEHQPICQEKQFICDKCGKRYKCKSNLLDHISRYHSIKNHSVMCQTCGLIYKNKMSLNMHIQTQHLGIRRKRPKYPCDTCSKSFSRPTALRRHKVIHQVHTDFLCPVCQQGFNSKFYMHKHISEIHFDKRELTKYICQHCDAEYDNIWDLNAHKSETHVKNRYTCEVCGITCSKKSLLVIHMHTHTGVKPYACDECDKAFAQRNTLISHKKTVHGTEKPFSCTYCEKKFPVKGNLIKHIEGVHLRDKLEKKFVCSFCSKSFLRRKELMMHTAWHTGERNYKCTICGKSFVNSGALRRHKLIHDEKKHECEICLKRFHQKSNLKIHMKVHNKAL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -