Agra020222.1
Basic Information
- Insect
- Aphodius granarius
- Gene Symbol
- Zfa
- Assembly
- GCA_963971325.1
- Location
- OZ020225.1:19451442-19457184[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00022 0.019 16.2 2.2 1 23 222 244 222 244 0.98 2 14 1.1e-05 0.00095 20.3 0.4 1 23 250 272 250 272 0.95 3 14 4.3e-06 0.00037 21.6 1.3 1 23 278 300 278 300 0.95 4 14 0.00033 0.028 15.7 1.4 1 23 307 329 307 329 0.97 5 14 0.00015 0.013 16.8 3.3 1 23 358 380 358 380 0.98 6 14 1.8e-05 0.0016 19.6 0.9 1 23 386 409 386 409 0.97 7 14 2.5e-06 0.00022 22.3 2.6 1 23 416 439 416 439 0.98 8 14 2.6e-06 0.00022 22.3 0.5 1 23 445 467 445 467 0.98 9 14 1.1e-05 0.00093 20.3 0.6 1 23 473 496 473 496 0.95 10 14 9.6e-08 8.2e-06 26.8 1.0 1 23 503 525 503 525 0.99 11 14 3.2e-05 0.0028 18.9 1.0 1 23 534 556 534 556 0.98 12 14 6.2e-05 0.0053 18.0 4.8 2 23 562 583 561 583 0.98 13 14 6.8e-06 0.00058 21.0 0.2 3 23 591 611 590 611 0.98 14 14 3.5e-06 0.0003 21.9 0.8 1 23 617 639 617 639 0.99
Sequence Information
- Coding Sequence
- ATGTCTGACGTAAATTGGCTAATAGATTTTGAAAGCTTAGATTTGCAGAAAACCTGCAGAACATGCTTATCTCAAAGTACAGAAAACAGGAATTTATTTCTTGTTGAAGATGGTATCAAGCTGGCTAACATTTTGAAAAGCATAACAACAATTAAGCTTGCTGAAAATGATAATTTGCCACCAAATGTATGTGAAACGTGTGCTGACAGGTTGATGAAAATACTTGCGTTTAAGCAAACGTGCGAAGATATAGACGCAAAGTTGAACAAGTATTTTGATACCAAACAACGTCACAAAACACACGCCTTTGTTGAAGATGGGAAAACTACTGATTTAAAAATGGAATATTCGCAGAATGAAGTGGAAGCCACCAACACAGTGGTATCTTATTTAGTTATGGGAGAGCGTAACTATACAATTAGCAAGGAGCAATTTAAGGAACTTTCAAGTCAAAATTTACAAATTGCACAAGCAACAGAAGGGGAACATCATGACGAAAGTGCGGCAAAACTAATCAAAAATGAAGATGGATACATTATTCAATTGAACCCTCAGTTCTCACATAGCAAAATCCAAAATTACTTACATATCGAAACGCAAGATCCACTTGGATCGAATAGCACCCATTCTGCCGTATTGGATAATAGTATAGAGTCGAAAATGTTTCCCTGTGAAACGTGCGGTAAGATTTATTACAGCAAGAATGGGCTTCATAGACATAATAGGTCACACACTGGTGAACGGCCGTTTTTGTGTACAATTTGTGATAAACGATTTATCATGAATACCGATCTTCAAGCGCACTTAAGACTACATGATGGTGTAAGTCCGTATTTATGTAAGATATGCGGCaaaggtttcacaaaaaaatatacCCTTACAAGGCATGAGGTAACTCATGCGACGGAAAAAACGGTATTCAAGTGCGAACATTGTCCAACAGTATTTGACAATCTCAACATGTTGAAAGAGCATTCACTGTCACATGAGCCAAGTAATGAAGAAGAACAAGAGAAAAATGCTGAGGAGTTCGGAGATGAGGGTGGCAGTGTGGAAATCCATACAAAATATCACCAGTGCGAcgtatgttccaaaatatacatgcaTGCTAGTTCCTTAAAGGAACACATGAAAAATCATGATGATTCAGTACAGTTTGTTTGTAGCATCTGTGGACAGACGTTCCGGACAGAGAAACGTCTTAAGGACCACGCCAGGAAGTTGCATGATGTGAGAGAGCGGCAGTACAAGTGTAACGTCTGCCCAAAGACGTTCAAGCAACGTCACAGGCTTAATACGCATATAAATGTGATACACACCGGTATACGACCATTCACCTGTGCGGTATGCGATATGGCGTTTAAATCAGCTACGCAGCTCAGGAAACACTATCGTGTGCACTCTCATTACAGGCCGTACAAATGCGACATCTGCCCGAAATCGTTTAAAACCCAGGAGGCGATGAAGTACCACGCGCTATCGTCTCATACGGACAAACCGATTGTTTTTACATGTAAAATATGCGGTAAAGTGTACAGTAGAAAAGGTGGCTACCAGTCGCATATTAGGACACACCAGCAAAATTACATGGAAAAAAGACACACGTGCCACGTCTGTGGAAAAGGCTTTCCGCTGGGCTCTATGCTCAATGTTCACATGAAGATACATTCAGAGCCAAATGTAAAATGCCCCGAATGCTCTAAGCTATTTCGTAGCCATATTCATCTGAAACGTCATATGACCACCCACTCGTCTGAAAAAATGGCAATCTGTCCAATTTGCGGGAAAGCTATTAGCCGGTTTGGAAAATTGAAGATTCATATGCGAACGCATACTGGTGAGCGGCCATATGTCTGCGATATCTGCGGGAAGGGATGTACGACATCAACAATGCTGAAGGTGCACGTTCAAACGCACTCTAGGAGTGGTAGAAAAAGAGATATATCTGATGTTGGTGAAGCTCTTCAGATTAAAGAAGAACTTGATGAGGATAGTTAA
- Protein Sequence
- MSDVNWLIDFESLDLQKTCRTCLSQSTENRNLFLVEDGIKLANILKSITTIKLAENDNLPPNVCETCADRLMKILAFKQTCEDIDAKLNKYFDTKQRHKTHAFVEDGKTTDLKMEYSQNEVEATNTVVSYLVMGERNYTISKEQFKELSSQNLQIAQATEGEHHDESAAKLIKNEDGYIIQLNPQFSHSKIQNYLHIETQDPLGSNSTHSAVLDNSIESKMFPCETCGKIYYSKNGLHRHNRSHTGERPFLCTICDKRFIMNTDLQAHLRLHDGVSPYLCKICGKGFTKKYTLTRHEVTHATEKTVFKCEHCPTVFDNLNMLKEHSLSHEPSNEEEQEKNAEEFGDEGGSVEIHTKYHQCDVCSKIYMHASSLKEHMKNHDDSVQFVCSICGQTFRTEKRLKDHARKLHDVRERQYKCNVCPKTFKQRHRLNTHINVIHTGIRPFTCAVCDMAFKSATQLRKHYRVHSHYRPYKCDICPKSFKTQEAMKYHALSSHTDKPIVFTCKICGKVYSRKGGYQSHIRTHQQNYMEKRHTCHVCGKGFPLGSMLNVHMKIHSEPNVKCPECSKLFRSHIHLKRHMTTHSSEKMAICPICGKAISRFGKLKIHMRTHTGERPYVCDICGKGCTTSTMLKVHVQTHSRSGRKRDISDVGEALQIKEELDEDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -