Basic Information

Insect: Aphis gossypii
Gene Symbol: -
Assembly: GCA_004010815.1
Location: NW:233453-236903[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.3e-06 0.00032 20.5 2.3 1 23 113 135 113 135 0.99

2 7 7e-06 0.00052 19.8 2.0 1 23 141 164 141 164 0.94

3 7 0.039 2.9 8.0 3.5 1 23 170 193 170 193 0.96

4 7 0.01 0.77 9.9 2.5 1 23 201 223 201 223 0.95

5 7 8.2e-05 0.0062 16.5 0.2 1 23 229 252 229 252 0.98

6 7 1.3e-06 9.8e-05 22.1 1.7 1 23 257 279 257 279 0.95

7 7 3.9e-05 0.0029 17.5 5.4 1 23 285 308 285 308 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.3e-06	0.00032	20.5	2.3	1	23	113	135	113	135	0.99
2	7	7e-06	0.00052	19.8	2.0	1	23	141	164	141	164	0.94
3	7	0.039	2.9	8.0	3.5	1	23	170	193	170	193	0.96
4	7	0.01	0.77	9.9	2.5	1	23	201	223	201	223	0.95
5	7	8.2e-05	0.0062	16.5	0.2	1	23	229	252	229	252	0.98
6	7	1.3e-06	9.8e-05	22.1	1.7	1	23	257	279	257	279	0.95
7	7	3.9e-05	0.0029	17.5	5.4	1	23	285	308	285	308	0.97

Sequence Information

Coding Sequence: ATGGCTACCTACAGCGATAATAGTTATGATTCACAAGTGTTAGAAGATTCAGTCTTGCAAtgtaaacagacttttgaaaatatcttaTGTGTTCAAACTACAGcgttattgaaaaaatcaacactcgaaaaaatttttgtagtattacaggaatttatgtgtaaaattaatgatagtgAATCTACCATTCAAGAAGTGATACAGTCTGAAAACAACTTCAATAAAACaatctgCAAAGAAGtagaatttaaaagaaaatcaaattGCAAGGCGTTTGATAACTTTAAAGCTTTATGTAGTGAAAATAAATCACCTTcTGTAAAAAGACAAAATATCTACAAATGTGCAGATTGCAAGTACCAAACACCTAGAAAATCTGATTTGAAAAAACATCTAAAACGTCACATGGGTGTATGCGACTATTTCTGTAGTTATTGTGAGCgaaaattttttgataaatacaaCTTAGAGAGGCATGTAAATGCCAGTCACactaaaaaacaacaatattcgTGTACATTGTGTACGTACACAACGTTTTTATATGATTCATTAAAACgtcacaaaaaattaaaacatagtgACCACATaggaacaaaatatgtatgttcCGTTTGTTACCATGTGAGTGCTACAAAACATGATTTAAATGTGCATTCATATAGTCACAATAAAGTTAAATCTTACATGTGTGAAGAATGTGGTTCAATGTTTGCTATCAAAAGCCGATTGATAACACACCAGAACACTGTACACAATGAGCCTGTTCATCCATGTCAAATTTGTGacaaatcatttaaaacaCTGACGCTGCTTAAAAGACATACAGTCATACACTCACGTTTTAAACCTTATTGTTGTCCATTTTGCAACCATTCATCCAACAGCCAGAGCAACTTGACCAAACATGTACGCAAAATTCACTCTTTGGATGATTTTTCTTACCACAAatttattaatggaaaataa
Protein Sequence: MATYSDNSYDSQVLEDSVLQCKQTFENILCVQTTALLKKSTLEKIFVVLQEFMCKINDSESTIQEVIQSENNFNKTICKEVEFKRKSNCKAFDNFKALCSENKSPSVKRQNIYKCADCKYQTPRKSDLKKHLKRHMGVCDYFCSYCERKFFDKYNLERHVNASHTKKQQYSCTLCTYTTFLYDSLKRHKKLKHSDHIGTKYVCSVCYHVSATKHDLNVHSYSHNKVKSYMCEECGSMFAIKSRLITHQNTVHNEPVHPCQICDKSFKTLTLLKRHTVIHSRFKPYCCPFCNHSSNSQSNLTKHVRKIHSLDDFSYHKFINGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00463579;
90% Identity: iTF_00973268;
80% Identity: -