Basic Information

Insect: Aphidoletes aphidimyza
Gene Symbol: ZFX
Assembly: GCA_030463065.1
Location: CM059999.1:42492331-42496519[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0013 0.075 13.7 1.1 1 23 280 303 280 303 0.97

2 9 6.1e-07 3.4e-05 24.2 2.8 1 21 309 329 309 330 0.96

3 9 5.5e-06 0.00031 21.2 3.8 1 23 575 597 575 597 0.99

4 9 1.6e-06 8.8e-05 22.9 3.5 1 23 603 625 603 625 0.98

5 9 4.2e-05 0.0023 18.4 2.1 1 23 658 680 658 680 0.99

6 9 4.1e-05 0.0023 18.4 0.8 1 23 686 708 686 708 0.98

7 9 0.92 51 4.7 5.6 1 22 715 736 715 739 0.90

8 9 0.017 0.92 10.2 0.4 1 23 742 765 742 765 0.92

9 9 6e-05 0.0033 17.9 0.8 1 23 771 794 771 794 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0013	0.075	13.7	1.1	1	23	280	303	280	303	0.97
2	9	6.1e-07	3.4e-05	24.2	2.8	1	21	309	329	309	330	0.96
3	9	5.5e-06	0.00031	21.2	3.8	1	23	575	597	575	597	0.99
4	9	1.6e-06	8.8e-05	22.9	3.5	1	23	603	625	603	625	0.98
5	9	4.2e-05	0.0023	18.4	2.1	1	23	658	680	658	680	0.99
6	9	4.1e-05	0.0023	18.4	0.8	1	23	686	708	686	708	0.98
7	9	0.92	51	4.7	5.6	1	22	715	736	715	739	0.90
8	9	0.017	0.92	10.2	0.4	1	23	742	765	742	765	0.92
9	9	6e-05	0.0033	17.9	0.8	1	23	771	794	771	794	0.96

Sequence Information

Coding Sequence: ATGCGTTTGACCGATGTGCGGCGTGAAGTGGACGAAATGCTCGAGGGATTTGAGCACCAAGCAACATTCTCGTTGAAGAAAATTAATCGACGCTTCGAATCGTTGGGCCAGTCACTTGACGAGGAGTTCAGACAATATTTTCTGCAAGTTTCGATTGGAAGATTGTCAACCAGTTACACCAAAGTCCAAATTGAAACCAGAAGAGATCAAACGGAAAATGGTGGCTTCATCAACGAAACTTCAATTCAGACTGGATATGGTTTGACTGACGAAGATCAGTCAACTAGTTCACTTTTGGATAGTTCAGTGAAAAAGGTAAGGACAAACTCAGTTGATGAGTTTGATGATGACAATGTGGATGTGAAGTCGGAAAAAGATGCAAATCAGTTGGACTCCGTGGTAGAAATACTCAGCTCGAGTGACAAAGAAGATATCGAATCGCAAAACTATCGattacaaaccaaaattgaatgggAAGAAACTGATTGGATGAATGATGCGATTGACAGCGACATGAGTCACAACAATGACGAAAGGAACATTGATGAGGTGACAATCAAAGAAGAATTCTATATTGAACCCAAATTAGAAGTGATCGACGTAGACCCAAACGACGTCTTTTTGAACAGTGAATACAGTACAAGCAATAACgtcataaatgaaaatcgtaCTGGAACTTCACGACGGTCGTCACGACTGAAAGATGGCAATAAGAAACCACAGtgttcaaatgattcaaaacgATTCAAGTGTAAACATTGTGATTATGGATGTTTTGATAGATTTCCGGCGAGGAGAGAAATGGAAGCTCATGAAAAACGCTGTCGCAATCGTCGTTACGAATGTGAAATCTGCAAGAAATATGTCACTTCCGATAAAACTCAAATGGAAAGACATATGCGAAGCCATACGGGTGAAAAACCGTTTCAATGCGATATTTGCAAGAAATGCTTCAATCAAAGGAGCAATCTTAAGCGACACTTGAACGCCTTTCAAATGCGTTTGACCGATGTGCGGCGGGAAGTGGACGAAATGCTCGAGGGATTTGAACACCAAGCAACATTCTCGTTGAAGAAAATTGATCGACGCTTCGAATCGTTGGGCCAGTCACTTGACGAAGAgttcaaacaatattttctacAAGTTTCGATCGAAAGATTGTCAACCAGTTACACCAAAGTCCAAATTGAAAGTAACAGAAATCAAACGGAAGCTGCTGGCTTCATCAACGAACCTTCAACTCAGATTGGATATGATCTGTCTGACGATGCTCGGTCAACTAGTCCGATTTTGGGTAGTTTAGTGAAAGAGGAAAGGATTCACTCGATTTCTGACGATGAAAATGTGGATGTGATTTCGGAAAAGGACGCAAATCAGTTGGACTCCGTGGTAGAAATACTCAGCTCGAGTGACAAAGAAGACAGCGATGAATCGCAAAACTATCGattacaaaccaaaattgaatgggAAGAAACTGATTGGATGAATGATGCGACTGGCAACGAAATGAATCACAACAATGACGAAGAGAACAGTGATGAGGTGACAATCAAAGAAGAATTCTATATCGAACCCAAAATAGAAGTGATCGACGTCTCTTTGAATGGTGGATACAGTACAGATAATGGCATCACAAATAGGAATCGTGCTGGAACTTCACGTCAGTCTTCACGACTGAAAGATGGCAAGGAGAAGCCATCATGTTCGAAGGATTCAAAACGATACAAGTGTAAACATTGTGATTATGGAAGTGATTACAAAGGCAATCTTAATAAGCACATGCGAACGCATACCAAAGAGAAACCCTTTCAATGCAGCCGTTGTGCTAAATGCTTTACACAGTCATCCAATCTGAATGCACATATGACGATGCATAAGGATGAATTTCCGTTCCATTGCTCCAAATGTTTTCGTGGATTCTTTCAAGACAATGAAAAAGGTGCGCACGAAAAGAACTGTACATTTCGTCCCTATGAATGCTATGTTTGTAAATATGTCACCATTCAGAAGATACATTTGAAAGTACACATGCGGACGCACACCggaaataagccatatcgatGCAGTCGTTGCTCCAAAGGATTCGCTCAATTGTGGAGTCTCAAACAGCACATGACAATTCACAAAGACAAAAGATTGCCATTTCATTGTAAAGGATGTTTTCGTAGATTTCCGAAGGAAAGTGAACAGAAAGCTCATGAAAAAAGCTGTCGACATCGTCGTTACGAATGTGATATTTGCAAGAAGTTTGTCACTGCTGTTAAAACAAATATGGAAAAACACATGCGCGTTCACACGGGTGAGAAACCGTTTCAATGCGAGGTGTGCATGAAACGCTTCACTCAAAAAGGCTCACTTAAAATACACTTGAACAACATTCACAACAGACGCAAATTGTAA
Protein Sequence: MRLTDVRREVDEMLEGFEHQATFSLKKINRRFESLGQSLDEEFRQYFLQVSIGRLSTSYTKVQIETRRDQTENGGFINETSIQTGYGLTDEDQSTSSLLDSSVKKVRTNSVDEFDDDNVDVKSEKDANQLDSVVEILSSSDKEDIESQNYRLQTKIEWEETDWMNDAIDSDMSHNNDERNIDEVTIKEEFYIEPKLEVIDVDPNDVFLNSEYSTSNNVINENRTGTSRRSSRLKDGNKKPQCSNDSKRFKCKHCDYGCFDRFPARREMEAHEKRCRNRRYECEICKKYVTSDKTQMERHMRSHTGEKPFQCDICKKCFNQRSNLKRHLNAFQMRLTDVRREVDEMLEGFEHQATFSLKKIDRRFESLGQSLDEEFKQYFLQVSIERLSTSYTKVQIESNRNQTEAAGFINEPSTQIGYDLSDDARSTSPILGSLVKEERIHSISDDENVDVISEKDANQLDSVVEILSSSDKEDSDESQNYRLQTKIEWEETDWMNDATGNEMNHNNDEENSDEVTIKEEFYIEPKIEVIDVSLNGGYSTDNGITNRNRAGTSRQSSRLKDGKEKPSCSKDSKRYKCKHCDYGSDYKGNLNKHMRTHTKEKPFQCSRCAKCFTQSSNLNAHMTMHKDEFPFHCSKCFRGFFQDNEKGAHEKNCTFRPYECYVCKYVTIQKIHLKVHMRTHTGNKPYRCSRCSKGFAQLWSLKQHMTIHKDKRLPFHCKGCFRRFPKESEQKAHEKSCRHRRYECDICKKFVTAVKTNMEKHMRVHTGEKPFQCEVCMKRFTQKGSLKIHLNNIHNRRKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -