Basic Information

Insect: Aphidecta obliterata
Gene Symbol: Spef2
Assembly: GCA_963966015.1
Location: OZ014431.1:9216962-9228646[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.9e-06 0.00051 20.8 0.8 1 23 1915 1937 1915 1937 0.98

2 7 1.3e-05 0.0014 19.5 0.3 1 23 1943 1965 1943 1965 0.98

3 7 8.5e-07 8.9e-05 23.2 0.8 1 23 1969 1991 1969 1991 0.99

4 7 9.1e-07 9.6e-05 23.1 1.4 1 23 1997 2021 1997 2021 0.98

5 7 0.00015 0.015 16.2 2.8 2 23 2028 2049 2027 2049 0.96

6 7 0.0012 0.13 13.3 3.7 1 23 2055 2077 2055 2077 0.98

7 7 1 1.1e+02 4.1 1.1 1 21 2080 2100 2080 2101 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.9e-06	0.00051	20.8	0.8	1	23	1915	1937	1915	1937	0.98
2	7	1.3e-05	0.0014	19.5	0.3	1	23	1943	1965	1943	1965	0.98
3	7	8.5e-07	8.9e-05	23.2	0.8	1	23	1969	1991	1969	1991	0.99
4	7	9.1e-07	9.6e-05	23.1	1.4	1	23	1997	2021	1997	2021	0.98
5	7	0.00015	0.015	16.2	2.8	2	23	2028	2049	2027	2049	0.96
6	7	0.0012	0.13	13.3	3.7	1	23	2055	2077	2055	2077	0.98
7	7	1	1.1e+02	4.1	1.1	1	21	2080	2100	2080	2101	0.95

Sequence Information

Coding Sequence: atgctaCAAATAATCCAAGAATGGTTGATGGACTCTCTAGGACTCATCATAGATTTTAAAAGGACCGATTTCGGTAAAAGGGTCAAAGACGGCTTCCTCATAGGTCAAGTGCTTCGCGGATTCGAGTTGATATCGAAAGAGGAACTATCCCTAATCAAACCGACTGAAGACAGAGAAGTGGCCATGAGCAATTTCATGAATTACGTCCTTATCTGGCTGGGAAAACTGGACATAAGACTGAAAGACGTGGAGCTAGAAGGATTATTGGATGGTAAAGGCAGAGTGGCGATTAATTTGTTCTACGAGTTGTACTTGGCTCTTCAGAATAAATCGAAACTCCATATGATAACCCAAaaacgaattatagaaaaatccAAACCACCGCATCCTAAATTCGAAGTGAAGAAGGTCGGGGAATCGAAGCTGGACGAACTCAGTCTACATCTCAGTCCCTACTGTATTCCACTCATGAAAAACAGAGACATCATAAGGTGGCACAAAGACCGCCTAGCTTCCTTAACAAAACAATGCGAAGAAGCGAGGAGAGAGTATTCGAGATATTTCAACACCAGAAGAAACGAAAGACCCCCCACCCTAATATGCACCTGCAACCTCCAGTGCGTTTGTCCAAAGAACGAATCCAAGAAGGACCAAGTAGATTACCCTGAAGAAGCcagtcaaaatttcacattcgaGGAACTAACCAAGCAATATAAAGAATCtacgaaattgaaaaaacacgTACCAAACTTGGACGAGGCGAAACAAGTCGTTAAAAAACTAAAAACGAGAAGGTTGGACAACAGGGAGAGGGAGCTACAAAAGATGCGTTTACACACCGAACTCTGCGAGGAATTTTGGAACGAAATGGTCAAGAACCAGGAGAAACAGATCGAGGAGCTCGTCGACGATAAGATATCCACGCAGTCCTTCTACGAGAAACAAATGATCAACAAGATGTTCCAGGTCAAACACCAGCAGGAGGTGATAAAAGAGAATAGGAGTTTCGTGAACGAGGAGATAATGAAGCAGAAGGAGCAGGATATCCTCCAGAAACTCTACATGGAACAGAGGATGTCGGACGAGTGCATCTGCGATTATCTGTACGAGAAGGAGAGGATAAAACAGTTGCATCGGAGGGTGTACGCGGAGAAGCAGAGGTTGAAGAAGGCCAGGATCGAGAAGATATGCAAGGATACGGTCGAAGATTTGGCGAACTTGGCCATTAGAATCGGGGAATTCAGGGAGAGCTACAAAGAGGAACCCTCGAGGAGGAGATACGACGATTGGGTCAGTCTGTTCGTTACTTGCGGTCCTATTTTACCGAGAGTGGTCCCCACTGAAGATATTGTTCAGGACCTCTCGGAGTTGCCGGAAGAAGAAGAGCCTGCATTCATAGAGGAGATTAACAGGCAGGAAATCGTAGACGCCAAAGATTTCGAGAAGTACCATAGGAACGAGTGGCCTTGGGAACTAGATAACCTCGGTGAATTGAAGATGGATTTCAAATTGATAGAGAGAGGTATGAACATCATCGGCTACATAGTGCACAGGCTGTTGGCGGCGAAATACCCCACCACGCCCCTGATGCCGAGACCAGACTTCAAATTCGAATGTTCCGCGTGCATCAACGGCTTAACGGACACGACAATAGCCGGAAAACTTCAGAGTTTACTCAGTTACAAAGACATCGAGGTGTTCGAAGTCTTGAACGCCGTGAACTACTGCCTGGACAGGTACGCCAGCGAGCAGAAACCGGAGGAACACGTGGACTTGCAATCTTTAGACATGGAACAAATGGAGGGAGAAAAGTCGAAGAGTAGCTCTATGTTGATGAAGGGGAAAAAGGGGAAATTGCCGAGGGAGTCGGATAATTCGAGAAGCGCGCTGTCAGTTAGCGAGAGCGCAACCGTAGATTGGCCTCCagtaatgaataaaaaacaccAAACACCCCGGGTGTATCCATGCGAAGAGGTCAAGATGTCTCACGCCGCTTCGCTGGGCGAAATCGCccaaaattcattgaatttggGCGAACCACTGACAGATTATCTCTTGGCTGCCATGATCGTGGAGTATCTCTATTCCATCTCCAACAAGAAGGGTTGGGCTTTGGTGAATTACCCCACGAACTACAACCAAGCCGTTACTCTGGAGGAGAACTTATCGTCCACGCCACTGTGCAAAGATCTGAGCGCCATCAAGAGCATAATGGACCTCTCGGACCTCGAGGACAAGCACGTGGAGGGAGCGATGAGGAAGGAGAGGAACCCGAATAGGTATTCCAAGTTGTTTCCTCGACCTCCGAAGCACAGAGACGACGACGTTTACGACACTGTCCTTACGGCCTACATAAAGATCATCAAAACTCCCCTGGACGGTTTAGAAGGAGCTGAGAGTGACCTTCCACCCATCACCAGGTACGTCGACGAGTCGGCCGAACCTCTGGAGAAGTTCTACGCCGAACAAGGTTGCGCCTACTTCATGTTTTACGAAACCTTCGACTACAACACCGTGAAGTACTTGGCCAGATTGGTCATTGGGGATTTCAGCTTACCCAGAAAACCATCGATAGAACTCTTCGGAAGGTCTGTACTTCTTGGACAGGAGGAGGTCGAGGAAGAGGGGGGGTCTAGGTTTCCCAAGTCTTCCAAGGAGATATCAGTGAAGGAGAAAGATAAGAAGAAGCTGTACGTGCAGaaggaagaggaggagactGTGGTGAAGGATAAGAAGAGTAAAGGTAAAGACGAGAAGGGTAGTACAGAGAAGAAACCCAAGCAAGGCAAATCATCTGAAGCGTTGATGAAGACCACCTGGGAGAACAAGCAAGTCCAGGTACCACCCTTAGAAGACATATACGAGATCATCGTCGAAGAGGAGGACCTGGACGTCCTCCCAGGCGAAGAAAAGTGGAAGTACCTCGAGATACCCATGTCCGAAGAGCTCCAACACATCCTCGCCAAAATGTGCGAGAACATGGAAAACCTCTACATCGAAGACTTCAAACAGATCCTCTTCATGCGGAGACTCGTCTTGAACAGTGTCCAACCCTACATCTCGCACACCAAGAGTCACCTGCTGGAGTTCCTCCAGCGGCCCGACGACCGTCAGCAGATCCTGCACGAGTTCCAGGCGACCTTCAACGGCATCTCCGAGTGCCTGAGGTCGGACGACGAGGTCAAGGCGGAGCTCCACTGCAGGGCGGAGGAGTTGAGGAAGGCGCTGCAGGCGACCAGCGAGCGGAACATCGCGGAGTCTTTCGGGGAGAGGGAGAGGATCGTCGAGATGCACTGGTTGCGGAAGGAGCTCCACGAGTTGACGCAGATCTATCTGTGCGCGATGCAGCTGGAACTCGACAGGTTCGTCGACACTATACAATTATTGACCGATTATTACGTCTCTGGAATAACGAACATGCCCCCTGAAGAAGCTGCGTTTACTAAGGAATTTATTCGAGTGTTGGAGTCGGACAGCGTTCATACCTACGAAAGTTACAGCATGTGGGAGGATTCTTTCGATAACAGATACTTCAACGATAAGATGGCGGGGAAGGTGACGAAGAGCTCGGATTTCGTCGAGAAGACCAAATATTCGGCTCTTAAAATTGTGGTTAACACGCAAGGAAAATTCGCTCTGGGAAAACCGAAACCGGAGAAACAGAAAGGAAAGGGGGCGCCATCTATAAAAATGTCCGACATAGTAAGGGACAACATGGACAAGCTCGTCGAGGAATGGAAGACGGCCATAGAAGGAGAATCGGAAAGGGTCGTCCTCAGGCTTCGCCTGCTGAAATGCGACAGCGAGCACCGATTCCGGGAGATGACGGCGAAGGTGAGGGACATGATGAACGAGATATACGGTCTGATCCGCAGGAGGTACAACAACGAGCAGTCGAGCATAGATCGGCTCTGCGACGTCGTGGCGAACGCCATAGAGAACGAGACTCCCATCCAGATCGAACTGGTCATCGACAGGGATCAGTTCTACGTTCAACCGGAGGTTCTTCTTTTTCCCGACGACCTGCCGCCGCCGCCGCTTCCTGTCAAGGAATGGAAGAAGGAATCTGTGTTCACGATGGCGCAGTTGAAGGATTTACACAGGGTGTTGTTGGATATGGCGCCCAACGGGACAATACCAGAAAGACAGTTCACGTTCCTGCTGCAAGACATGTTGGTGCACGACGTGGAAGACGGCAAGGAACCCCTGGCTCCCGACATGTGGCGCCTACTCACCACCCTCGAACTGGAGAAGGTCGTCAACGAGCTCTTCTCCAAGTCCGAATGCGTCCACTGGAAGGACTTCATCATCTACAACCTCACGATCGCGATGCCGACCTCCGAACAGCTGATAGAGCTGAAGAGGGGCTTCCAGAAGAGGGATAGGGGCAACACCGAAAACGTCTCGGTGCAGGAGTTCAACGCCCTCAAGTTCTGGTTCGAGGAGTGCTTCCGCAAGACCGACGAGTGCGACATGATGAGGTTGAGGTTGATGAAGGAACTCGTCTGCGATTTATATAAGATCGACGATGACACCGTGAACTACTCCGCCATGTTGGTGGATTTCTGCAAGGACCACGTCGGAGCTGTCGGGTTCGCCAAGCTTTTGGGGCTCATTCTGGACCGTCCGGTGTGTTGGGACGCTAATATAGGTAAGAAATACGTCCAATATCAAATGCTGCACAGGGAAGAACACGAGACTTGCGTGAAACACCGTGATGAAGAGATCAGGGGAGATGCGAAGATGGTCGAGGATTTTCTGGGGGAAATAGCGGACGAAACAGTCCATCAATGTGACAGTGTCGTCATAACTGATGTTCCTGATACTCCAAACTCCAAGGAGATCTTGAGTATCGAAGGGGAAACATGCGGCGACCCTTGTCTTTGCGATCTGAGGTGTTACTGCGGCGACCAACCGGAGGAGACTTTTTCGAATTTACCTATTGACTTTGAAGAAAACTTCGACCCTTCCCTGGTGTATTTCTTGGATTTCGAGCCGATTTTGGCTGCTGAAGCTGTCGTGTTACACTGGTATACCCAGGTGCAGAATATAGACGGTAAAAGTTTCCGACAAAAGGCTGAAGAAATATATAACGAATGTAAAAATCCGTCTTTCAATAATTCAGTTTTGGCCCATGAATTTTTGAATCACTACAAGTTTTCTCAGTTACTTGCAAATACAACGAGGTTCACTGATAAGAATCCCTCGAATTACATACAGAATCTGATTAAATTCAGAAAGAATGGTATTGAAAATTATCCGAACCAGTGTGTCGAGGTTTTACCGTTAGAAAATATAAATGTACCTTTACATGATGACATGCTGAGAATTGTCGAGAATTCAAACGTATATACAACAAATTTACAGGAGAACCTTAGTGATTACATGAATACAGCATCAAGGTACATTCCATATTACCCGGAGTGTAATAACACTGTTTTGAGGCATTCGTCTAATATTGAAAGTATTCCTATTCAAAATGATCCAGACTCGAGTTATGAGTACACACATGAAATCAACGAAAACATTAAATCGTTTGATAAAAACTGTACAGATTCATTCACAACGCAAAATGAATTAAACTTGGAAAAATGCTTCAATGAAAACATAAATGAAGGGAATTTCAGTACGAAAATATTAAAATCCAAACCCACAGATAACTTGGTTTCCGTAGAGTCggtcagaaacaaattgaatttaTCGAACGAAGTCGTTAAACATAAAACCAAATCCCAAAAAACTTATAAATGCCCGCACTGTGATAGAGTTTTCATGAGAAGAATTTCCTTGAACTCCCACATAGCGATACACACTAAAAACCGCCCATTTGTGTGCTCCAAATGTGGCAAGGCGTTTCCGATCAAAAGTGAATTGACAGTacataaaaaaatacattccGATCAATACCAGTGCAAGATATGTTTGAAAACTTTCGTGGTGCCGAGCAAACTAGAAAGACATCTTAGAACGCACACCAACGAGAGACCGTTCAAGTGTAATTTCGTAAATTGCGGGAAATCGTTCTCCGATCAGAGCAATTTATTGGAGCACAAGAATACGCATAAAGATGGTAGGAATTTGAAATGCGGTAATTGCGAGAAATATTTCAAGACGAAGAGTCAGCTGAAGAGTCACAAACTGAGTCATAAGTCTGACGTTTGTTTTACTTGCGATATTTGCAAAAAGTCTTATAAGTATAAGACTAATCtgatttttcatttgaagaagcaCACAGGATATACCTGCCCTTTTTGTAGTTTAAATTGTGAAAAACTGTCTGTGCTAGTCAAACATAGAAAAGAATGCAATAAAAATAAAGTAAACTAA
Protein Sequence: MLQIIQEWLMDSLGLIIDFKRTDFGKRVKDGFLIGQVLRGFELISKEELSLIKPTEDREVAMSNFMNYVLIWLGKLDIRLKDVELEGLLDGKGRVAINLFYELYLALQNKSKLHMITQKRIIEKSKPPHPKFEVKKVGESKLDELSLHLSPYCIPLMKNRDIIRWHKDRLASLTKQCEEARREYSRYFNTRRNERPPTLICTCNLQCVCPKNESKKDQVDYPEEASQNFTFEELTKQYKESTKLKKHVPNLDEAKQVVKKLKTRRLDNRERELQKMRLHTELCEEFWNEMVKNQEKQIEELVDDKISTQSFYEKQMINKMFQVKHQQEVIKENRSFVNEEIMKQKEQDILQKLYMEQRMSDECICDYLYEKERIKQLHRRVYAEKQRLKKARIEKICKDTVEDLANLAIRIGEFRESYKEEPSRRRYDDWVSLFVTCGPILPRVVPTEDIVQDLSELPEEEEPAFIEEINRQEIVDAKDFEKYHRNEWPWELDNLGELKMDFKLIERGMNIIGYIVHRLLAAKYPTTPLMPRPDFKFECSACINGLTDTTIAGKLQSLLSYKDIEVFEVLNAVNYCLDRYASEQKPEEHVDLQSLDMEQMEGEKSKSSSMLMKGKKGKLPRESDNSRSALSVSESATVDWPPVMNKKHQTPRVYPCEEVKMSHAASLGEIAQNSLNLGEPLTDYLLAAMIVEYLYSISNKKGWALVNYPTNYNQAVTLEENLSSTPLCKDLSAIKSIMDLSDLEDKHVEGAMRKERNPNRYSKLFPRPPKHRDDDVYDTVLTAYIKIIKTPLDGLEGAESDLPPITRYVDESAEPLEKFYAEQGCAYFMFYETFDYNTVKYLARLVIGDFSLPRKPSIELFGRSVLLGQEEVEEEGGSRFPKSSKEISVKEKDKKKLYVQKEEEETVVKDKKSKGKDEKGSTEKKPKQGKSSEALMKTTWENKQVQVPPLEDIYEIIVEEEDLDVLPGEEKWKYLEIPMSEELQHILAKMCENMENLYIEDFKQILFMRRLVLNSVQPYISHTKSHLLEFLQRPDDRQQILHEFQATFNGISECLRSDDEVKAELHCRAEELRKALQATSERNIAESFGERERIVEMHWLRKELHELTQIYLCAMQLELDRFVDTIQLLTDYYVSGITNMPPEEAAFTKEFIRVLESDSVHTYESYSMWEDSFDNRYFNDKMAGKVTKSSDFVEKTKYSALKIVVNTQGKFALGKPKPEKQKGKGAPSIKMSDIVRDNMDKLVEEWKTAIEGESERVVLRLRLLKCDSEHRFREMTAKVRDMMNEIYGLIRRRYNNEQSSIDRLCDVVANAIENETPIQIELVIDRDQFYVQPEVLLFPDDLPPPPLPVKEWKKESVFTMAQLKDLHRVLLDMAPNGTIPERQFTFLLQDMLVHDVEDGKEPLAPDMWRLLTTLELEKVVNELFSKSECVHWKDFIIYNLTIAMPTSEQLIELKRGFQKRDRGNTENVSVQEFNALKFWFEECFRKTDECDMMRLRLMKELVCDLYKIDDDTVNYSAMLVDFCKDHVGAVGFAKLLGLILDRPVCWDANIGKKYVQYQMLHREEHETCVKHRDEEIRGDAKMVEDFLGEIADETVHQCDSVVITDVPDTPNSKEILSIEGETCGDPCLCDLRCYCGDQPEETFSNLPIDFEENFDPSLVYFLDFEPILAAEAVVLHWYTQVQNIDGKSFRQKAEEIYNECKNPSFNNSVLAHEFLNHYKFSQLLANTTRFTDKNPSNYIQNLIKFRKNGIENYPNQCVEVLPLENINVPLHDDMLRIVENSNVYTTNLQENLSDYMNTASRYIPYYPECNNTVLRHSSNIESIPIQNDPDSSYEYTHEINENIKSFDKNCTDSFTTQNELNLEKCFNENINEGNFSTKILKSKPTDNLVSVESVRNKLNLSNEVVKHKTKSQKTYKCPHCDRVFMRRISLNSHIAIHTKNRPFVCSKCGKAFPIKSELTVHKKIHSDQYQCKICLKTFVVPSKLERHLRTHTNERPFKCNFVNCGKSFSDQSNLLEHKNTHKDGRNLKCGNCEKYFKTKSQLKSHKLSHKSDVCFTCDICKKSYKYKTNLIFHLKKHTGYTCPFCSLNCEKLSVLVKHRKECNKNKVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -