Apic020849.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphaenogaster picea
Gene Symbol
-
Assembly
GCA_003063865.1
Location
NJRM01000127.1:39497-42684[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.033 3.7 8.6 0.2 3 23 451 473 450 473 0.94
2 10 0.002 0.22 12.5 1.4 1 23 479 503 479 503 0.98
3 10 0.00018 0.02 15.7 0.2 1 23 509 533 509 533 0.97
4 10 0.00022 0.025 15.5 0.1 3 23 541 563 539 563 0.93
5 10 5.6e-05 0.0063 17.4 1.7 1 23 570 594 570 594 0.97
6 10 8.5e-05 0.0096 16.8 0.6 2 23 602 625 601 625 0.95
7 10 4.1e-06 0.00046 20.9 2.0 1 23 631 655 631 655 0.98
8 10 6.2e-06 0.0007 20.4 0.5 1 23 661 685 661 685 0.97
9 10 0.00028 0.032 15.1 1.2 1 23 691 713 691 713 0.99
10 10 0.0076 0.86 10.6 0.3 1 23 791 816 791 816 0.97

Sequence Information

Coding Sequence
ATGTCTTGCAGAGgagccgccgctgccgccgtcgccgcttgCACGTCGAGACGACACAGTCGCGAAAGAATCAGCTCCGAGGGCGAGGGAGCGGAATGCGCGCCCACCGATGCGTTTTTTGCCTCATCAAGGACAGACGAAGTCGGTAAGAAGGACCGAAAAACCAGGAGAAATGAGAGTTGGCACCAAACGCCAACTGGGAAAGGTGTTGATGTTGAGACGGTAGCCGACTTTGAGAAATGGCTCAAGATGCGCAGCACGGAGCCACCGGTGCCATCGAGCATGGACTTGGACACAGCCAAGGTAGTGGAAGGCGTAGACCGGTATCTAGGCGAAGAGGTGCTGTCACACGGCTGCTTTCTGAGCAAAGATCCATACGGCCTGTCTATCGATATCGATCTGGCAGATGCCAAGAAGCTCAACCTGTCATCAGGCTACGATCCGATACTGCAGGATCTGACGCACAGCGAGAATCGGCTATTGGAACCACCGTGCGAGAAAGTCGTCGACGAGTTTATGCTACCGGAATTCCAACTGGATCATCTGGATCCACTAGCAGCGCTCACACCAGATGATATGATGGTGGCCGGTGAGATTCTGCCATCTGCGAGTAACCAGCCAACACTAAACATAGAGAATCAAGATGTCGAACAAAACGCTCCAAAAACAGGAGTTCCAGAACAGAACAATGAGACACTCTGCGAGAAATCCACGCAGGTTACCCTCAATCAGCTACCGGTGAATTTGGTTGTGAACGAGATTGAAGATACAAAGACAGAACAGGAAGCTATAGTACAACCTTCAGGAAGTTCCTCTGAGCTCTTCATCGGAACCTTATCGTCAGTGGAGGAGAGCACGTCGAATACCATGACGAATTCCATAGAAATAGACACGCGGGGCATGGTAATAGAACAATTAAAGAAGACGAAACTCGAGCCTCGTATCATTAAGAAACGTCGACAGATGACAGAGCAATTGGAGAAACTCGACAAACATATCAATGGCAAGAGCTTTGCCGTTGATGCAGATTCGCAGGATGGCATGATGGCTGTGGTCGCTATATCTACTGACAAGATCTCCAACATGACACAGATCGTTATCAATACTGGCACAGAGAAACAGATCTATCAGGGCAAGACCTCGGAATTGATCGAGGCAACAGGCAATTTTCCAAAATTGCCCAAAATAGATACTTCTGCCGCGATTTGGAATGGTACGGTAGAGTATGATACCGATAGTAATCCGAATAGTCAATATGAAATTGTTATATCCAATGCATTGGAAGAACTAGGCATCACCGATGACAGTCTGCAGCCCTTATGTGCCACCGAACACGACAAAGTATGGCTCTGCCCACGAGATGGCTGCAACAGACAATTCGGCAGATTGTATACTCTGAAGGGTCATTTGTTAGCCCACTATGGAGTTAGACCGTTTAAGtgCGACTTCGAGGGCTGCACTTGGGCCTTTTATTCCGAATTCAAGCTCAAGAGACACAAGGAAACACATCTAAAGCGCAAGGATTACGTGTGCGAGGTGGAAGGCTGCAATCGTCGTTTCACTACTGTCTATAATCTGTGGAGCCACGCAAAACTGCACAGTCGTCCTAATCGGATCGTTTGTCAGGTGCCAGACTGTGATGAAAAGTTTCAGACAAAACGAGCGTTGGAACTACACATGAAGTCGCACGACCAGCGTCATGCACCTTACGTGTGTCAGCACGAAGGTTGCGGCAAACGTTACTACAGCAGCAATGCATTGACGTCACATCAGCGATCACATAGCTATAAAGAAGTGGACATCAAGTGCTCATGGCCGGGCTGCGGCAAGATTTTCGATAAGCCATGCCGACTCAAGGCCCACATGCGTTCTCATACCGGCTACAAACCTTATCCTTGTACTTTCCAGGACTGCAAGTGGGCCTTTTCATCATCTAGCAAACTTAAGCGCCATCAGAAGAAGCACACAAACGAGCGCAAATTTGTATGCGACGTGCCAGAATGTGGCAAGGCGTTTATGCGCTCGGAACACTTGAAGGAACACCGACTGACGCACACGGAAGGTCGCTTCTTCCAGTGTTTTGTATGTACTGCCCGATTCTCCGCCAAGAGCAGTTTGTACGTGCACATCAAGAAACATCAGCAGACCAAACCGGATTTAAATGTAGCCAGTGATATGTCCGAGTGCACTTCCGGTGATCAGAAACGCACGAGAACGAGAGAATCTCATTGCTCGCGAGTGAAGCCGATCAAGCCGAAGCGATGGAACACAGAACTGATGAATGCTGCTGAGACTATCGCGGAGGAAAACGGCGTCGAGAAGCAGGATGCCAACGTATGTTCCCAGGATGAAGATCAAATGGAATGGCTATATCGTTGCCCGATAGATATATGCGGGCATTTGATCAGCAGCGAGACGAGTCTTCGCGAGCACATGTTAAAATCACACAGCATACATTGTGACGATTTGCTGACTAAACCGTCTTCGGACGATGCCGATATAGATTACGTTTTATACACCGTGCATAGCTCGCCCCCAAGTTCACCAACTGCCGTCGAGGAGGAACAGATGGTCATGGTGACTCCATGCGATGCCGTCATCCTTGATACTTCTTCCCCAAGAACGGATCATTGTCTGCCGGAACCGGAACCGCCACCTTTCGACACCTTGTTAAAGAGCTCCGAAACGTTCCAAAACGACACGCGAACTGACAAGCGGATCGACAATGACACTGTACCGGTGAAGGAGCAGGGCTCGGCAAGGACAGATTTAACGTATTCCGACTGGTCTAAACTGAAAAAGAACAGTCCGTTGATGGATTCGGTAGTGACGGAAACGTCGGACGTTGTACTGGGCGCGAGTGGTGATCTAAGCGAGAGTTTGTTGGTCACGGAAGAACTGCCTTCGATGTACTATCAGGATGATGTGGCAGGTACGGAATACCAGGTGTTGTTATTAGATTCAAGTCCGCTCGAGAGTGCCAATAATTTGCGCGGTCTCGAATGA
Protein Sequence
MSCRGAAAAAVAACTSRRHSRERISSEGEGAECAPTDAFFASSRTDEVGKKDRKTRRNESWHQTPTGKGVDVETVADFEKWLKMRSTEPPVPSSMDLDTAKVVEGVDRYLGEEVLSHGCFLSKDPYGLSIDIDLADAKKLNLSSGYDPILQDLTHSENRLLEPPCEKVVDEFMLPEFQLDHLDPLAALTPDDMMVAGEILPSASNQPTLNIENQDVEQNAPKTGVPEQNNETLCEKSTQVTLNQLPVNLVVNEIEDTKTEQEAIVQPSGSSSELFIGTLSSVEESTSNTMTNSIEIDTRGMVIEQLKKTKLEPRIIKKRRQMTEQLEKLDKHINGKSFAVDADSQDGMMAVVAISTDKISNMTQIVINTGTEKQIYQGKTSELIEATGNFPKLPKIDTSAAIWNGTVEYDTDSNPNSQYEIVISNALEELGITDDSLQPLCATEHDKVWLCPRDGCNRQFGRLYTLKGHLLAHYGVRPFKCDFEGCTWAFYSEFKLKRHKETHLKRKDYVCEVEGCNRRFTTVYNLWSHAKLHSRPNRIVCQVPDCDEKFQTKRALELHMKSHDQRHAPYVCQHEGCGKRYYSSNALTSHQRSHSYKEVDIKCSWPGCGKIFDKPCRLKAHMRSHTGYKPYPCTFQDCKWAFSSSSKLKRHQKKHTNERKFVCDVPECGKAFMRSEHLKEHRLTHTEGRFFQCFVCTARFSAKSSLYVHIKKHQQTKPDLNVASDMSECTSGDQKRTRTRESHCSRVKPIKPKRWNTELMNAAETIAEENGVEKQDANVCSQDEDQMEWLYRCPIDICGHLISSETSLREHMLKSHSIHCDDLLTKPSSDDADIDYVLYTVHSSPPSSPTAVEEEQMVMVTPCDAVILDTSSPRTDHCLPEPEPPPFDTLLKSSETFQNDTRTDKRIDNDTVPVKEQGSARTDLTYSDWSKLKKNSPLMDSVVTETSDVVLGASGDLSESLLVTEELPSMYYQDDVAGTEYQVLLLDSSPLESANNLRGLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00128451;
90% Identity
iTF_00128451;
80% Identity
iTF_00129957;