Basic Information

Gene Symbol
-
Assembly
GCA_003063725.1
Location
NJRN01000003.1:1147926-1150563[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.15 17 6.6 1.1 1 23 159 182 159 182 0.97
2 9 6 6.9e+02 1.5 0.6 2 20 295 315 294 318 0.84
3 9 0.12 13 6.9 0.4 1 23 358 381 358 381 0.95
4 9 7.5e-09 8.6e-07 29.5 2.5 1 23 387 409 387 409 0.98
5 9 2.5e-05 0.0029 18.4 1.9 2 23 425 447 424 447 0.95
6 9 6e-05 0.0069 17.2 0.4 1 23 453 475 453 475 0.98
7 9 0.0019 0.22 12.5 1.7 1 23 481 503 481 503 0.97
8 9 0.00034 0.038 14.9 3.3 1 23 509 532 509 532 0.98
9 9 0.11 12 7.0 0.4 1 23 539 561 539 561 0.93

Sequence Information

Coding Sequence
ATGAGTGAAGAAACCAATGCAGACGTATCCTACTTGAGCTGTGATATAAATGGCACAAGATATATTTACAAGCTCGCGCCGTCACCGACAGACATTGCAAAAGACTCGGCGTCGAATGAAGAACAAAACGCAGTGGACATTGTCAAGGGAACTGAGTTGGACAATGGAGAAGAACCAATTTCGTTAGTGTGTTTGAATGGACAGGTATACGCGATTAAAAATGGAGTAATTGACGAGTTGGACGCCGACCAGTCTATGGAACGGACGAGTTGCCACGAAAAGACACTCTTGATATCAAAGACGGAAAACGTGGAAAGCAACGAAAATGACTATATCACCAATGAGAGTATAGCAATCGATAGTCCGTACAGACAATCTGAGGAGCAATACAAGGTCGCTACAGAAGAAGCAGCGAGGGATCTTGTAGAGAACGACAATGTTAACGTCGACGATTTCTTAGAAGTTGTGACTGCTTTTAAATGCAAGATGTGTACTTACCTGTCTCAGGACAAGATGCAATTGTTAGGTCACATTCAAAAACTACATTTAGATTCTACTGTAGATATTAAAccaAAGGAAGAATCTAAAATCGTGGATGAAGTAAGAATAGTTTATATGTGTGCGGAGTGTTCCCACTGCTTCCATTCTTTTGAGGACTGTAGAGAACACATGATTAATGATCATCAATTAACAGACATTGCGAGTGATGAAGCTGGAAAAGAAAATTTGACAGACCTGACGAACCCTGGCCTGATGACTGAACACGGGGGCCAACATACCGAAAGCAACGAAGTGGAAAAAGGTccagtaaaaatttcaaagaccTTAAATTCAGAATATATGCGTAATAGAAAAATGATAGAATCAACGGAAAGAAAtgtaaaGTGTTCTTATCAGGGCTGCCCATACAAATTCGCCTCGGAAGAAATTATGCAGCAACATATTCTTTGCCATACAGAATCGGAGACTGCGACGACATTCAAATGCAGCGTGTGCcgagatatgaagtttacaaagTGGCGCCAATGTAGCTTGCATTTATGGAAAAAGCATCAAATCGACATAGGTTTGTTTACTTGTAAAATTTGTGAAGCCTACAAAAGTGCTACCATGGTAAAACTCTTGACGCATATGAGGGTGCACAGTGATACTCGTGACTACAAATGTCCTGATTGCGGGAAATGTTTCAAACAAGCTAGCCAGTTACGCAATCACCGTATAATGCATTTAGATCGCAAAACGTTAGAAGTAACTCGATGGTACACTTCTAAGAAATGCGACATGTGCGGTAAAACTTATGCGAACTCGAAATGTTTAAAGAATCACATTCAAGCTGTACACTCCAAGTTACGTCCGTACGTTTGTAATGTTTGCGGTCATGCTAGCGCCAGAAAGGCAATGCTGCAAATGCATTTGCGTCAACACACGGGAGATAAGCCCTTTAGCTGCGAGATTTGTGAATACAAAACTGGAGATCACAATACCTTACGACGGCATATTATGCAACACACGGGATTTCGACCGTACAAATGTCCACATTGCTCATATACCGCGATACAGAGCAGCagttataaaaatcatttaaagtCGAGACATCCTTTATTGTCTGGCTTATTTACATGCGATCTGTGTCCTTTCAAAACGGTGAAAAATGAAAGTTATATTCAGCACTTGGGAGATCATGAAAAGggtttaataaaatctaatgtGCAGAAAAAAGATAGCGAGAATGTCGAAGTCTTTCCCGGCAATATTGCGGCAGCGCAATTAGTTTATAGCTGTTTAGGTGCCTTTTCGAAAGACGGGGATACGTTAGAAGCTAATTTGATGTCTTCCTCAACGTCTGCTGATGGTACTTCTCAAACAATCACAATACAAATACCATCGAAACATCTTCAGGGTTCATTATCAACAAGAGAAAGTTTCAACAAAAATGATTCTACCATTGAGCAAGAAGATGATGAAACGATGCATTGCTTCTTAAAAATTCCtagagaagaggaagaaagcATAGACACTGGTGGTATAACGATACCTGCAGAACCTGAAGAAAGAAGTGTTAGAACCATGGATATTGAAGAGACAAACATAACGACCAGTGATATTGAAGAGACAAATGTGacaaatattgatattgattcgtga
Protein Sequence
MSEETNADVSYLSCDINGTRYIYKLAPSPTDIAKDSASNEEQNAVDIVKGTELDNGEEPISLVCLNGQVYAIKNGVIDELDADQSMERTSCHEKTLLISKTENVESNENDYITNESIAIDSPYRQSEEQYKVATEEAARDLVENDNVNVDDFLEVVTAFKCKMCTYLSQDKMQLLGHIQKLHLDSTVDIKPKEESKIVDEVRIVYMCAECSHCFHSFEDCREHMINDHQLTDIASDEAGKENLTDLTNPGLMTEHGGQHTESNEVEKGPVKISKTLNSEYMRNRKMIESTERNVKCSYQGCPYKFASEEIMQQHILCHTESETATTFKCSVCRDMKFTKWRQCSLHLWKKHQIDIGLFTCKICEAYKSATMVKLLTHMRVHSDTRDYKCPDCGKCFKQASQLRNHRIMHLDRKTLEVTRWYTSKKCDMCGKTYANSKCLKNHIQAVHSKLRPYVCNVCGHASARKAMLQMHLRQHTGDKPFSCEICEYKTGDHNTLRRHIMQHTGFRPYKCPHCSYTAIQSSSYKNHLKSRHPLLSGLFTCDLCPFKTVKNESYIQHLGDHEKGLIKSNVQKKDSENVEVFPGNIAAAQLVYSCLGAFSKDGDTLEANLMSSSTSADGTSQTITIQIPSKHLQGSLSTRESFNKNDSTIEQEDDETMHCFLKIPREEEESIDTGGITIPAEPEERSVRTMDIEETNITTSDIEETNVTNIDIDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00885434;
90% Identity
iTF_01407680;
80% Identity
iTF_00127741;