Aash006085.1
Basic Information
- Insect
- Aphaenogaster ashmeadi
- Gene Symbol
- TTLL12
- Assembly
- GCA_003063805.1
- Location
- NJRQ01000848.1:10746-16753[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0059 0.67 11.0 3.4 2 23 1010 1032 1009 1032 0.95 2 13 7.7e-05 0.0087 16.9 0.5 1 23 1038 1060 1038 1060 0.98 3 13 8.6e-06 0.00097 19.9 2.6 1 23 1066 1088 1066 1088 0.96 4 13 0.00027 0.031 15.2 1.9 1 23 1097 1119 1097 1119 0.97 5 13 3.9e-05 0.0044 17.9 2.3 1 23 1125 1147 1125 1147 0.98 6 13 8.9e-07 0.0001 23.0 1.6 1 23 1152 1174 1152 1174 0.98 7 13 0.0067 0.76 10.8 4.0 1 23 1181 1203 1181 1203 0.99 8 13 0.00053 0.06 14.3 0.1 2 23 1223 1244 1222 1244 0.97 9 13 5.2e-05 0.0059 17.4 0.7 1 23 1250 1273 1250 1273 0.97 10 13 0.031 3.5 8.7 1.6 1 23 1279 1301 1279 1301 0.96 11 13 0.00092 0.1 13.5 3.4 1 23 1307 1329 1307 1329 0.98 12 13 3.2e-05 0.0036 18.1 2.4 1 23 1335 1357 1335 1357 0.98 13 13 3.3e-05 0.0037 18.1 0.4 1 21 1363 1383 1363 1384 0.94
Sequence Information
- Coding Sequence
- atggaTGGCGTTGACTTATTTAATGTGTTTCTTGTAACACATAAACTGCAACTTCAGTCCTATGGTGTCCCACAATTATTCtggaaagttttatataagaagCTGAAAGATCAAATTTATGATGCAGGCCTTGTCTTCCAGCTGACAAGGGTAGAATATGAAAATGGAGAAAAACATGTTACAGAGCCAATATGGAAGCTAATTGTATCTACGGAGAATGGCATTTCTATACAAGattccaataatatttatcttattgatCATGCGTGGACATATGACGTCAGTAGTGCTCAACAGAATTTAATTCAAGTACCTGGCTTACTTGATCGAATGGGCATTCTCATGGGACTAAACACTGAGGCAGATGAGCAGGAGAAAGTCGAGAatgttataaaagaaatgtggCGTTACAATCAATCATATTCGGTGAATTATGGGGAGATAGAAGATAGAATGCCAATATGGTATATCATGGATGAGGTTGGTTCAGCGATAAACCATAGCAATGAGCCAAATTTTAGAGCCGTGCCCTTTCTGCATATGCCGGAAGGTGTAATTTATACGCTTCTATTTCCTGTAAGAAACGTTGCTTCAGGAGAAGAAGTGACGAGAGATTTTGTAGAAGGTCAGACGAAGGATTCCGAAAAAAGACGTGCGCTATTATTGCCTTGGGTCCACAGCACATTTGAGGACGAAAGTTTTGAACAGAGCGAGCCGGatgaagattattttttagcaGGTCATATTCCCGAAAGTTTGCCGGAGAAACTGGATGTAATCAAGGCAGATACCAGTAGaagattaaaagttttttcacAATACAGTTATGTGAATGATAACTTGACAGATCCAGCATTTGAAATCACCGATAATGAAGAAGAGGCAGACATACTATGGCTCGTGTCTCATTACAAGACGTACAAAGAATTGAATGTTTCCTCGCCCCacgtttttataaatcaatttccATATGAGAACGTTTTGACAATAAAGGATCTCTTATCGATTGTATGCAGAAGAAAAGCAATGGACAAATTGTACGATTCAGATACTCTGGAAACTTATCCAGCATGGTTACCGACGACGTATAATCTGAGCACGGAATTGGTACAATTTGTCGCTTATTTCATGCAACGAGCAAATGAGGATTTGGACAATCATTGGATTTGCAAACCATGGAACTTGGCGAGAGGCCTGGACACTCACATCACGAACGATCTCTATCACATTCTGCGGCTGCCTTGCACAGGCCCGAAAATCGCGCAGAAGTACATCGCGCGGCCAGTTTTGTGCAACAGACCGGACGTTAATCAAGTGAAATTCGACGTGAGATACGTCGTATTGCTCAAATCCGTAAAGCCGCTACGCGCGTACGCTTACGCAAACTTCTTCCTGCGCTTCGCGAATCAGTCGTTCGCGTTGAACAATTTTGATGCATACGAGCAACATTTCACCGTAATGAATTACACCGAGGAGAATCCGCTCTTCCACGTGAAATGCGCCGATTTCATCGTGGAATGGGAAAATCAGTATCCCGATTATCCCTGGAAAACCTACATCGAGCCGAAGGTCCTCTCCGTCCTGCGACAGGTCTTCGAAGCCGCGGTCGCGCAGCCGCCGCCGAAAGGAATAGCCGAGAGTCCGCAAAGCAGAGCCGTGTACGCCGCCGACTTGATGCTGGAATGGAGAGATTGCGAGATGCAGCCCAAGCTGTTGGAGATAAATTTTATGCCCGATTGCCAGCGGGCGTGCGAATATTATCCGGACTTCTACAATGATGTTTTTAAATGCTTGTTCTTGGACTTCGACAATCCAGAGGTGTTCCATGCAGCTAAAGTATGGGCGGAATGTTGCGGCAGATCGGATTTAGCCGCAAAGTCGAATGCGGAATTgcatttgaattattacatttgttcTCACCATATTGAAGATCGCTGTTATGTAAGCAAAACTGTTCCCGTTATTATAGAAGAAGGTACCATCCCTACTCTATTCGGCACCGACTTGACTACTGGTGAAGACTCAATAAATATGTTTGATAAAGCACAGCGTCTCCAAGAAGTAGGTGATAGCGTGCCTCTAACATATTGCGATATGAATGTCGAGATAGACGAGTATCATGATATCAGATTTGCCAATTTATGTCGAATCTGTGGCAAGTCTGCTCTGGATGGAGTAGACATGTTTGCAGCCAAGGGCATAGAACTTAAATTAAAGGAAAGAATAAATCTGCATATGCCTATCTCGATTGACATAGACGATTCGTTGCCACAGAAAATATGTACAGATTGCTGCAATAAATTGGAAATTGCACACTCATTAGTCGTATCATGTCTAAGAACCGATATGCGTTTGaagaaatttctaaatattgaGAAAGAGTCAGAATATGAGAATAAGTACAATGCATTGGTTGACGAATGTTCATTAGAGATAGTACAAGAAATGTGTGTAAATGATAATACGCATCCTAATTcatttactataaataaaatgataaattctgATTCAGAAATAAGTTTGAGAGgattagaaatacaaaataataattttcagagCATTGGGAAAAGTGTTGTGCCATTAGAACTCAGTACTCTAATCCAAACTTGCAGAGAagttaatagtaaaaataatgtgaCTATTACGGAAGAAATATCAAAAGTTCAACAAGACATCCAGAAGATTCAGAATAGAAGCCTTAGCGTTTTATGTTTGCAGTGCCAAACTTTCTATGAAACACAGGAGATATTTgagaatcataaaatattttgtagcaAGGAGCAAAATGTCGCTAaacaaatagatatatttagaaCTGCAGAAAACGAAAAGTATGGGAACAAACAGGGTAATcatgaaatagaaaattcCCAGACATGCAATAAAAGATTTGATGGCAAGCAAGTTATTGATAACGTTAAAAGCTGTGAATCAATGCATTGTACTGTTTGTAACCAAGTATTCAAATGTCAGCAGGATTATGACAATCACAAATATCTTCATGGAAATCTTACTGAAGTGACTAAAAGATGTGGTCATTGTAAAAAAGTATATCATAACAGAAAGGACTTGTTAATTCACATCATGGAATCGCACGAGGGACGACTATTATTTAAGTGCTCTACATGCGATAAAACATACGAGAAATGGTCTAGCTTAGATATTCACGAAGCTACTCACAGAATAGATAAGCCTTATCTTTGTGATCTGTGCGGAAAAAGCTTTAAGCATTCCAATAATTTAAGAGGtcataaaagaattcatttggACGAATCTATAAAGAAAAGGCACGTGTGTGAGATCTGTGGTAATGCGTTCAGATCaggATTTCATTTGCGAGAACATATGAATCAACACGATGGCAACAGACCCTATTCTTGTGAACAGTGCGGAAAAACCTTCTACAAGAGAATTCAATTACGACAACACAAATTATCGCATGGCTCTAATAGGCACACATGTCCGATTTGCGGTGCAACGTTTAATCGTAGAGGGAACATGAACACGCACATGAAACGGCATAATAACGGTAATGGAGGATATACATGCAGtGTTTGTGCTTACAAATGTAAGTCTATGAGCGAATTGAAGATACACAGGAAAAAGCATACTGAGGAGGAAATAGTGGACAgcattaagaaaaaatgtaccGACAAGGAGATATGGCgttgtaatatttgtaataaaatattcccgAAGCGCGCTGTCTTGTTAAATCACGAGCGCGTACACGGAGATGATAAGTTTTACGAATGTGATGAATGCGGCAAGAAATTAGCAAGTAAAAGCTCGCTGATGTATCACAAGAAGTCGATGCATCTGAGAGAGAAATCGCACATGTGTCACTATTGCGGAGATTCGTTCGTTTCGAGAGAAGCGCGATTGATTCACGAGAGGATACATACCGGTGAACGTCCGTACGTCTGCAAGGTGTGCAATATGCGGTACAGATGCTCCAGTAATCTCAGCCAGCACATGAAGATCCACACGGGTCTGAAGCCGCACAAGTGCCGTTTTTGCAACAAAGGTTTCACGCGCAAAGGTGCGCTAACCGTGCACGAGAGAATTCACACGGGCGTTAAGCCTTATCCTTGCGAGACATGTGGTAAAAGCTTCTCGCAGAAGAATGACATGTTAAAGCATGCCAAACGCACAACGGCAGATCGATGCAACGGAGCCAGCGCAACGAGATCTTCAAATGGGAAAAAGAATATGTTAAAGCATCCTGTGGTACACGAGCAAGATACCTTAGTAATTTCAAATGTCAATTCGTCACATATTCTTCAAGTTTATGTCAATACTAGCGTCTCTtcggaaattaaataa
- Protein Sequence
- MDGVDLFNVFLVTHKLQLQSYGVPQLFWKVLYKKLKDQIYDAGLVFQLTRVEYENGEKHVTEPIWKLIVSTENGISIQDSNNIYLIDHAWTYDVSSAQQNLIQVPGLLDRMGILMGLNTEADEQEKVENVIKEMWRYNQSYSVNYGEIEDRMPIWYIMDEVGSAINHSNEPNFRAVPFLHMPEGVIYTLLFPVRNVASGEEVTRDFVEGQTKDSEKRRALLLPWVHSTFEDESFEQSEPDEDYFLAGHIPESLPEKLDVIKADTSRRLKVFSQYSYVNDNLTDPAFEITDNEEEADILWLVSHYKTYKELNVSSPHVFINQFPYENVLTIKDLLSIVCRRKAMDKLYDSDTLETYPAWLPTTYNLSTELVQFVAYFMQRANEDLDNHWICKPWNLARGLDTHITNDLYHILRLPCTGPKIAQKYIARPVLCNRPDVNQVKFDVRYVVLLKSVKPLRAYAYANFFLRFANQSFALNNFDAYEQHFTVMNYTEENPLFHVKCADFIVEWENQYPDYPWKTYIEPKVLSVLRQVFEAAVAQPPPKGIAESPQSRAVYAADLMLEWRDCEMQPKLLEINFMPDCQRACEYYPDFYNDVFKCLFLDFDNPEVFHAAKVWAECCGRSDLAAKSNAELHLNYYICSHHIEDRCYVSKTVPVIIEEGTIPTLFGTDLTTGEDSINMFDKAQRLQEVGDSVPLTYCDMNVEIDEYHDIRFANLCRICGKSALDGVDMFAAKGIELKLKERINLHMPISIDIDDSLPQKICTDCCNKLEIAHSLVVSCLRTDMRLKKFLNIEKESEYENKYNALVDECSLEIVQEMCVNDNTHPNSFTINKMINSDSEISLRGLEIQNNNFQSIGKSVVPLELSTLIQTCREVNSKNNVTITEEISKVQQDIQKIQNRSLSVLCLQCQTFYETQEIFENHKIFCSKEQNVAKQIDIFRTAENEKYGNKQGNHEIENSQTCNKRFDGKQVIDNVKSCESMHCTVCNQVFKCQQDYDNHKYLHGNLTEVTKRCGHCKKVYHNRKDLLIHIMESHEGRLLFKCSTCDKTYEKWSSLDIHEATHRIDKPYLCDLCGKSFKHSNNLRGHKRIHLDESIKKRHVCEICGNAFRSGFHLREHMNQHDGNRPYSCEQCGKTFYKRIQLRQHKLSHGSNRHTCPICGATFNRRGNMNTHMKRHNNGNGGYTCSVCAYKCKSMSELKIHRKKHTEEEIVDSIKKKCTDKEIWRCNICNKIFPKRAVLLNHERVHGDDKFYECDECGKKLASKSSLMYHKKSMHLREKSHMCHYCGDSFVSREARLIHERIHTGERPYVCKVCNMRYRCSSNLSQHMKIHTGLKPHKCRFCNKGFTRKGALTVHERIHTGVKPYPCETCGKSFSQKNDMLKHAKRTTADRCNGASATRSSNGKKNMLKHPVVHEQDTLVISNVNSSHILQVYVNTSVSSEIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -