Asyr008316.1
Basic Information
- Insect
- Apeira syringaria
- Gene Symbol
- ZEB1
- Assembly
- GCA_934045895.1
- Location
- CAKOGY010000081.1:2301519-2325736[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.055 4.6 8.3 7.4 1 23 492 515 492 515 0.95 2 11 0.0077 0.64 11.0 0.5 1 23 521 543 521 543 0.96 3 11 0.047 3.9 8.6 3.5 1 23 547 569 547 569 0.98 4 11 7.6e-06 0.00063 20.5 0.8 1 23 574 597 574 597 0.98 5 11 8.1e-05 0.0067 17.3 0.1 1 23 601 624 601 624 0.95 6 11 0.00015 0.012 16.4 1.0 2 23 633 655 632 655 0.93 7 11 0.11 8.7 7.4 0.1 3 23 686 707 684 707 0.95 8 11 0.011 0.87 10.6 3.9 3 23 724 744 722 744 0.94 9 11 3.6e-05 0.003 18.4 0.9 1 23 750 772 750 772 0.98 10 11 6.2e-07 5.1e-05 23.9 2.0 2 23 778 799 777 799 0.97 11 11 0.00025 0.021 15.7 0.1 1 23 805 828 805 828 0.96
Sequence Information
- Coding Sequence
- ATGATAGCCCTATGTCGAGTTTGCCTGAGGACCAATCTGGAAATTCACAATATTGACGATGCTCTATCTAGTTTGTTTGATGAGCTTTGTGATTATGAGGGTGATTCCTTTGCTAAGTTTTGCAAAGAGTGTGTATATGAGCTGAAAAAGCTTCACAAGTTTAAAGAAAAATGTCAGCTGGCAACCAAAATTTTAAAAGATTGGAAGAAACAGAAACGGCCAGACAGAGAATCTCCAAATATGCTATCTGCAAAGATGCCACCGCCACAGCTAAGCCTTTGCAATAGGAAAAATTTAAAATTATACTATTATGAAGGTTGCCAACTGAATAAATCATATACCTCTGATATTATAGACTGTAATTACCCTCATATTGTAACCTTAAATGTACCAGATGATTCTTACAGTCATTCTGATGAATTTGAACGCTCTGCCAAAGTTCGAAAAAAATCTGAACCAATTACTGAGCCAGCGTTTAATTCTATTGTTGTTGAGTATGAACCAATTACTGAACCGCCCAGTGTTTCTAATGATACTGAACATGAACCAATTGCTGAAGTCACCATTAAATCTAATGCTGACAGTGAAACCAAACCGATTATAGAAGATGTTACTAAATCTAATGATTCAATTACCGAACCTACAATTACAGTAAACATGAGCAATGAATTACAATCAGATACAGATCTTAATAAAGTTAAATTTGAAGTCGACGTACAAATTAACAGTGTAGGTGATAATGACATGGAAGACATACACGACACATGGAGTTTCGAAGAAGTACACATAGATAATCTAATAGATATTGATATATTAGATGATAATAATAAGGCTAAAATTCGTAAAAACAATGCCACTAAACGTAATGATAGTAAAAACACACATGATAAACACAAAGTAGTAAAAGAAAAAACTGAAATGACCGTTGATGAACTAATCAATTCTTCGGATATTAAAACTGCGTATGATACAAGTGACGATGAGGTCTTAACATTGAAAAAGTTCAAAAAAGCAAAAAAGAAAGTATCGAGGAAACGGAGAATGACCCTTGCAGAGTTGGCTAGTTTCGATATGGATGCTGATGATTCTACCGGTGTAAAGAATGATGAAGTGGTCCTTAAGAAGCGTGGAAGAAAGATATCTTTGGAAGAGTTGAGACGGAGACTTGTCAAGCAGTTCAAGTATTGCGGCGAGGTGAAGGATGAAGAAGGGAATGTGATTGATACGGATGTGATATTGGAGAATTTAGACAGCATGCCGGTGCCTACGCTGCGGCAGTTGAAGAATCAGGTCTCGGCAGGAAATGGTATAAAAGTGCTAACCACGGCTAGTATAAAGTTGCTCGCTCAACTGCAGAAGAAATACAGCAACCAGTACTCGAACGCGTTCACAGCAGAGCATCTCGGCACGAAACAGCAAATAATGGCGGAGTTCGCCCAAAGGCAGCATTACGAGAGTTATGTCACTGCCAAGTATAGATGCGAGGAGTGCTATACCACTTTCAAGTCGCATAAAACGCTCATGTATCATAAGAAGGCTTGTCATAATGAGGCGGACCCGTACGCGTGCACGATATGCAGCGTGCGGTACAACAAGGAAGCCTCGCTCAAGTGGCACTACTTCTCACATCGGACCGTCTTCAAATGCAAACTCTGCCCCTTCGTTACTTATCAGAAACACACGATGATGCTGCATTACAATATTCACGCTGGCGTGTTTTACAATTGCAAAAACTGCGACGCGACCTTCAAGAGTAGATCCGGCCTCTACTTGCATATGAACACTGCTCATAAAACCAAATACGCGTGCGCCACCTGCGGACGTGGATTCTCAACGGAATATGGACTCAAAGTACACCAGTATATGGCACATCAGGAAGGCGAATTGGAGACGTCCACTTGTGACATATGCGATAAAACGTTCGACAACTACGAGAAGTACAAGAGACACGTCAGCTACTTGCACAGTGAACAACTGTCGGACATCATGAAGACCAAACGGCAGAAGGTCGATCGCGAGAAGGGCGATCGGAAGTACGGCGTACCTAACATGTTCTGCCCTGTGTGCAAGAAGCAGGTGAGCAGCGTGGGCGCGATGCGGTGGCACTTCAAGGTGGACCATCCGCACGAGAGCTTCGAGGTGCAGTACAGCGGCACGCACAAGCATCTCTGCCACGAGTGCGGGAAGGGCTTCCACGCCCTGTCGGAGCTGAACGACCACAAGAACCTGCACACGGGCGCGAAGCCCTACTCGTGCGCGCAGTGCGGCGCCACCTTCTACCGGAAACGGAACCTCACGCTGCACGTGTCGCGTCACAACCCGCCCTCCAAGGAGTGCAAGCTCTGCGGGAAGAAGTTCCGCAGCGGATCCAATCTATACAACCATATGAGGACGCACAGCGGTGACCGCCGGTACAAGTGCGGCATATGCCCCAAGGCCTTCCTCCACGCGAGCGCCCTCAGCGCCCACACGAGGGGCGTTCACAACCACATACGAAGAGTTAAGAAGAAAACATCGCCATCACCTCTTTATGAATAA
- Protein Sequence
- MIALCRVCLRTNLEIHNIDDALSSLFDELCDYEGDSFAKFCKECVYELKKLHKFKEKCQLATKILKDWKKQKRPDRESPNMLSAKMPPPQLSLCNRKNLKLYYYEGCQLNKSYTSDIIDCNYPHIVTLNVPDDSYSHSDEFERSAKVRKKSEPITEPAFNSIVVEYEPITEPPSVSNDTEHEPIAEVTIKSNADSETKPIIEDVTKSNDSITEPTITVNMSNELQSDTDLNKVKFEVDVQINSVGDNDMEDIHDTWSFEEVHIDNLIDIDILDDNNKAKIRKNNATKRNDSKNTHDKHKVVKEKTEMTVDELINSSDIKTAYDTSDDEVLTLKKFKKAKKKVSRKRRMTLAELASFDMDADDSTGVKNDEVVLKKRGRKISLEELRRRLVKQFKYCGEVKDEEGNVIDTDVILENLDSMPVPTLRQLKNQVSAGNGIKVLTTASIKLLAQLQKKYSNQYSNAFTAEHLGTKQQIMAEFAQRQHYESYVTAKYRCEECYTTFKSHKTLMYHKKACHNEADPYACTICSVRYNKEASLKWHYFSHRTVFKCKLCPFVTYQKHTMMLHYNIHAGVFYNCKNCDATFKSRSGLYLHMNTAHKTKYACATCGRGFSTEYGLKVHQYMAHQEGELETSTCDICDKTFDNYEKYKRHVSYLHSEQLSDIMKTKRQKVDREKGDRKYGVPNMFCPVCKKQVSSVGAMRWHFKVDHPHESFEVQYSGTHKHLCHECGKGFHALSELNDHKNLHTGAKPYSCAQCGATFYRKRNLTLHVSRHNPPSKECKLCGKKFRSGSNLYNHMRTHSGDRRYKCGICPKAFLHASALSAHTRGVHNHIRRVKKKTSPSPLYE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -