Basic Information

Insect: Apamea sordens
Gene Symbol: THAP3
Assembly: GCA_945859755.1
Location: CAMAOQ010000031.1:1236083-1268814[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.27 22 6.5 1.2 1 23 358 380 358 380 0.92

2 12 0.27 22 6.5 1.2 1 23 401 423 401 423 0.92

3 12 0.0024 0.2 13.0 1.2 1 23 430 453 430 453 0.93

4 12 0.36 30 6.1 0.2 1 23 457 479 457 479 0.92

5 12 0.14 12 7.4 0.9 1 23 484 507 484 507 0.97

6 12 0.0037 0.31 12.4 0.3 1 23 511 534 511 534 0.96

7 12 6.8 5.7e+02 2.1 0.1 2 19 546 563 546 566 0.78

8 12 1.3 1.1e+02 4.4 0.2 3 23 622 643 620 643 0.94

9 12 0.0051 0.42 12.0 0.6 2 20 659 677 658 680 0.92

10 12 3.8e-05 0.0032 18.6 3.1 1 23 686 708 686 708 0.99

11 12 0.00029 0.024 15.9 2.8 1 23 715 737 715 737 0.98

12 12 0.0041 0.34 12.2 4.0 1 23 743 766 743 766 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.27	22	6.5	1.2	1	23	358	380	358	380	0.92
2	12	0.27	22	6.5	1.2	1	23	401	423	401	423	0.92
3	12	0.0024	0.2	13.0	1.2	1	23	430	453	430	453	0.93
4	12	0.36	30	6.1	0.2	1	23	457	479	457	479	0.92
5	12	0.14	12	7.4	0.9	1	23	484	507	484	507	0.97
6	12	0.0037	0.31	12.4	0.3	1	23	511	534	511	534	0.96
7	12	6.8	5.7e+02	2.1	0.1	2	19	546	563	546	566	0.78
8	12	1.3	1.1e+02	4.4	0.2	3	23	622	643	620	643	0.94
9	12	0.0051	0.42	12.0	0.6	2	20	659	677	658	680	0.92
10	12	3.8e-05	0.0032	18.6	3.1	1	23	686	708	686	708	0.99
11	12	0.00029	0.024	15.9	2.8	1	23	715	737	715	737	0.98
12	12	0.0041	0.34	12.2	4.0	1	23	743	766	743	766	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTTCCAATGACACGAGAACAACTAACAAAAGCCATGGAATCACATTTCATATGTTCCCTAAACAGCTGGACCTCCGTACCGCTTGGGTGGAGGCTCTCGGCATGGCTGACTGGGAGCCGAAAGACAGAAGCACCATATGCTCTGAACACTTCAGGAGTGATGATATCTATGAGACCAAGGGTGGGTTGAGGAAGATAAAGTGTGGAGCAGTGCCTGTGGTGACGACACACTCTGCAGATGACCTTGACGCACCAGCCGCATTGAGGGTCTGCCGAATATGCCTTGCAATGGACAGAAAGATGTACCATATCAAAGAATTGAAGCTGGATCAAATGTATGAGCAAATCACTGGATTGATGGCTAGTTCAGAAGAGCGTCTACCGCAGCGTGTATGCTGGGAATGCGCCGGTCGTCTGAACTCTTCCTGTCGCTTCAGAAATAAGGCTTTGCGCAGCGACGCCTTGTTACACGATATGCTGCAGCCCGACACTTATATAAAAATCCGCGACATAAAATCGATAAATCGAAAACACAACCAACTCAGCTCTACCTTAATACATCAAATATACGAGAACGATGACTTCGACCTCCGCATCACAGAGTTCTCTAGCATAAAGGACGAAGAAATACCGAACACGTCCGATATTATACCGATCATTGCCGAAGATATTGACGTCAAAAGTTTGGCACCTATAAATGAAGTTGAAATTAAGGACGAAAGtagtaatgaaatattttttgaagaatATGACCATtttgatgatgacgatgacaaGGTTCTAAGTGAAGTTTATGTGGAGAAGAAGGAGAAGCCTAAAGTTAAGAAAAAGAGAGAAAAGGTTGTGAAGAAAGTTAAACCGCCGAAGAAAGTTGAGGAAGAAGATGATCCTGATACTACTAGAGATAAgtacaaaaaaaacgaCGTGAAACGCCGTCGAAACAACGAAGCTTTCGACGAGTCCTTATTCACAATCACTCCACTGACTTACGATCAGCAAATAGAAGAGATATTGAAAAGACAAGAGAGTTACAACTACACCAGCGCCCCCTATAAATGCACGATATGCTATCGAGGGTTCCAGATCAGGGATCGGTTTACCGCTCATTCTGTCAGACATACTGAGCAAATAGAAGAGATATTGAAAAGACAGGAGAGTTACAACTACACCAGCGCCCCCTATAAATGTACGATATGCTATCGAGGGTTCCAGATCAGGGATCGGTTTACCGCTCATTCTGTCAGGCATACTGAGcaaTGCGGTGCCTACGAATGTTTTATCTGCAAAACTAGACTCAAAACTAGTCGCGCGCTACGGAAACATCTAACGGCGCAACATACAGAGCAATATAGTTGTAAGGGGTGTCCGTTTGTCACTAGAAATAGaGGTGTAGCGAGGGAACATGAGAAATGGCATGCGGGGACTAAATACCAGTGTCCGCACTGTGCTAGTGAGTTTGATAAAATAACAACGTATATGGGTCATATTCGTATAAAGCACGTTTCCGATTTCGTATGTGAGCTCTGTGGGTACACGTTTGTCAGTGAGAAGGGGATTGCGGTCCACAAGAAGAAGAAACATCGGATTGATAAAGCGcTAACATTAGAAGGACCTTACTGTGAGCTGTGCGACGTAAAGTTCGTGTCAGAGGAGGCTCATGACAGACATCTGAAGTTATCTTCGAAACATAGCAGTGATCATGACCCTAACCGAATCCGGAATGATTCACAAAGCATGAACGCAGAGCGCAACGGCCGTGTTATGAGACGCATTGAGAGAAGGCCGGTCATACATCCGCGCTTACCGAGCGACAGTGACCAAGAGCCGCACACACCTGTTAATTGCGaacagTGCGGCATGCAACTTCGCGACCTACGAGTGTACGCGCAACACTTCAGACGGGCTCATCCGGACAAGAATCGAACCAAGTACCCCGCGATGAAGACCCCGTGCATGTGTGAGCAGTGCGGGAAGATATTCCAGAGCATGGCCCTTTTAAAAGACCATATGTGGGTCCACACCGGTGAGAAACGTTTCAAATGTGACCGCTGCACGAAAAGCTTCACTCAGAAGACGAACCTCGTGTTCCATATGAGGGTCCACAGCGCCTCGCGACCCAGCTACGAGTGCCCGCTGTGCGGGAAGCACTTCGCGTTCTTCAATAATAGAAGACGACATATGTttATCCATACGGGCCTGAAACCCTTCAAATGCGACACATGCGGCAAATGTTTCACTACAGCGGGCGAGCACAGGGCGCATGTCGAACATGTGCATCTGAAGAAACCGTGGCCCAAACGGGCTAGGCAGAGGAACAGGGACTGGAAATGCGATGACCCCAGTATTGAGGACTGA
Protein Sequence: MRCSVQNCSNDTRTTNKSHGITFHMFPKQLDLRTAWVEALGMADWEPKDRSTICSEHFRSDDIYETKGGLRKIKCGAVPVVTTHSADDLDAPAALRVCRICLAMDRKMYHIKELKLDQMYEQITGLMASSEERLPQRVCWECAGRLNSSCRFRNKALRSDALLHDMLQPDTYIKIRDIKSINRKHNQLSSTLIHQIYENDDFDLRITEFSSIKDEEIPNTSDIIPIIAEDIDVKSLAPINEVEIKDESSNEIFFEEYDHFDDDDDKVLSEVYVEKKEKPKVKKKREKVVKKVKPPKKVEEEDDPDTTRDKYKKNDVKRRRNNEAFDESLFTITPLTYDQQIEEILKRQESYNYTSAPYKCTICYRGFQIRDRFTAHSVRHTEQIEEILKRQESYNYTSAPYKCTICYRGFQIRDRFTAHSVRHTEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKALTLEGPYCELCDVKFVSEEAHDRHLKLSSKHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRLPSDSDQEPHTPVNCEQCGMQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSASRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRNRDWKCDDPSIED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00177644;
90% Identity: iTF_00449181;
80% Identity: iTF_00124342;