Basic Information

Insect: Apamea epomidion
Gene Symbol: THAP3
Assembly: GCA_947507525.1
Location: OX382255.1:5510164-5536441[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.21 15 6.7 1.2 1 23 345 367 345 367 0.92

2 11 0.0019 0.14 13.1 1.2 1 23 374 397 374 397 0.93

3 11 0.28 20 6.3 0.2 1 23 401 423 401 423 0.92

4 11 0.11 8 7.5 0.9 1 23 428 451 428 451 0.97

5 11 0.003 0.21 12.5 0.3 1 23 455 478 455 478 0.96

6 11 5.4 3.9e+02 2.2 0.1 2 19 490 507 490 510 0.78

7 11 1 74 4.5 0.2 3 23 566 587 564 587 0.94

8 11 0.0041 0.29 12.1 0.6 2 20 603 621 602 624 0.92

9 11 3e-05 0.0022 18.8 3.1 1 23 630 652 630 652 0.99

10 11 0.00023 0.017 16.0 2.8 1 23 659 681 659 681 0.98

11 11 0.0033 0.23 12.4 4.0 1 23 687 710 687 710 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.21	15	6.7	1.2	1	23	345	367	345	367	0.92
2	11	0.0019	0.14	13.1	1.2	1	23	374	397	374	397	0.93
3	11	0.28	20	6.3	0.2	1	23	401	423	401	423	0.92
4	11	0.11	8	7.5	0.9	1	23	428	451	428	451	0.97
5	11	0.003	0.21	12.5	0.3	1	23	455	478	455	478	0.96
6	11	5.4	3.9e+02	2.2	0.1	2	19	490	507	490	510	0.78
7	11	1	74	4.5	0.2	3	23	566	587	564	587	0.94
8	11	0.0041	0.29	12.1	0.6	2	20	603	621	602	624	0.92
9	11	3e-05	0.0022	18.8	3.1	1	23	630	652	630	652	0.99
10	11	0.00023	0.017	16.0	2.8	1	23	659	681	659	681	0.98
11	11	0.0033	0.23	12.4	4.0	1	23	687	710	687	710	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTTCCAATGACACGAGAACAACTAACAAAAGCCATGGAATCACATTTCATATGTTCCCTAAACAGCTGGACCTCCGTACCGCTTGGGTGGAGGCTCTCGGCATGGCTGACTGGGAGCCGAAAGACAGAAGCACCATATGCTCCGAACACTTCAGGAGTGATGACATCTATGAGACCAAGGGTGGGTTGAGGAAGATAAAGTGCGGAGCAGTGCCTGTTGTGACAACAGTGTGCCGAATATGCCTTGCAATGGACAGAAAGATGTACCACATCAAAGAATTGAAGCTGGATCAAATGTATGAGCAAATCACTGGATTGATGGCTAGTTCAGAAGAGCGTCTACCGCAGCGTGTGTGCTGGGAATGCGCCGGTCGTCTGAACTCGACGTGTCGCTTCAGAAATAAGGCTTTACGCAGCGATACCTTGCTACACGATATGCTGCAGTCCGACACTTATATAAAAATCCGCGACATAAAATCGATAAATCGTAAACACAACCAACTCAGCTCTACCTTAATACATCAAATATACGAGAACGATGACTTCGATCTACGCATCACAGACCTCTCTAGCATAAAAGCCGAAGAAATACCGGACACGTCCGAAATTATACCGATTATTGCCGAAGACATTGACGTCAAAAGTTTGGCGCCTATAAATGAAGTTGAAATTAAGGACGAGAGTAGTAATGAGATATTTTTTGAAGAATATGACCATTTTGATGATGACGATGACAAGGTTCTAAGTGAAGTTTATGTGGAGAAGAAGGAGAAGCCTAAAGTTAAGAAAAAGAGGGAAAAAGTTGTGAAGAAAGTTAAACCGCCGAAGAAAGTTGAGGAAGAAGATGATCCGGATACTACTAGAGATAAGTACAAAACAAACGATGTGAAACGCCGTCGAAATAACGAAGCTTTCGACGAATCGCTATTCACAATCACTCCACTGACTTACGACCAGCAAATAGAAGAGATATTGAAAAGACAGGAGAGTTACAACTACACCAGCGCTCTTTATAAATGTACGATATGCTATCGAGGGTTCCAGATCAGAGATCGGTTTACCGCTCACTCTGTCAGGCATACTGAGCAAAGCGGTGCCTACGAATGTTTTATCTGCAAAACTAGACTCAAAACTAGTCGCGCGCTACGGAAACATCTAACGGCACAACATACAGAACAATATAGTTGTAAGGGATGTCCGTTTGTCACTAGAAATAGAGGTGTAGCGAGGGAACATGAGAAATGGCATGCGGGGACTAAATACCAGTGTCCACACTGTGCTAGTGAGTTTGATAAAATAACAACGTACATGGGTCATATTCGTATAAAGCACGTTTCGGATTTCGTATGTGAGCTCTGTGGGTACACGTTTGTCAGTGAGAAGGGGATTGCGGTCCACAAGAAGAAAAAACATCGGATTGATAAAGCGCTAACATTAGAAGGACCTTACTGTGAGCTGTGCGACGTAAAGTTCGTGTCAGAGGAGGCTCATGACAGACATCTGAAGTTATCTTCGAAACATAGCAGTGACCATGACCCTAACCGAATCCGGAATGATTCACAAAGCATGAACGCAGAGCGCAATGGCCGTGTTATGAGACGCATTGAAAGGAGGCCGGTCATACATCCACGCTTGACGAGCGACAGTGATAATGAGCCGCACACACCTGTTAATTGCGAACAGTGCGGTATGCAACTTCGCGACCTACGAGTGTACGCGCAACACTTCAGACGGGCTCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACCCCGTGCATGTGTGAGCAGTGCGGCAAGATATTCCAGAGCATGGCCCTCTTAAAAGACCATATGTGGGTCCATACCGGTGAGAAACGTTTCAAATGTGACCGCTGCACGAAAAGCTTCACCCAGAAGACGAACCTCGTATTCCATATGAGGGTCCACAGCGCCTCGCGACCCAGCTACGAGTGCCCGCTGTGCGGGAAGCACTTCGCGTTCTTCAATAATAGAAGACGACATATGTTTATCCATACGGGCCTCAAACCCTTCAAATGTGACACATGCGGCAAATGTTTCACTACAGCGGGCGAGCACAGGGCGCATGTCGAACATGTGCATCTGAAGAAACCGTGGCCCAAGCGGGCTAGGCAGAGGAACAGGGATTGGAAATGCGATGACCCCAGTATTGAGGACTGA
Protein Sequence: MRCSVQNCSNDTRTTNKSHGITFHMFPKQLDLRTAWVEALGMADWEPKDRSTICSEHFRSDDIYETKGGLRKIKCGAVPVVTTVCRICLAMDRKMYHIKELKLDQMYEQITGLMASSEERLPQRVCWECAGRLNSTCRFRNKALRSDTLLHDMLQSDTYIKIRDIKSINRKHNQLSSTLIHQIYENDDFDLRITDLSSIKAEEIPDTSEIIPIIAEDIDVKSLAPINEVEIKDESSNEIFFEEYDHFDDDDDKVLSEVYVEKKEKPKVKKKREKVVKKVKPPKKVEEEDDPDTTRDKYKTNDVKRRRNNEAFDESLFTITPLTYDQQIEEILKRQESYNYTSALYKCTICYRGFQIRDRFTAHSVRHTEQSGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKALTLEGPYCELCDVKFVSEEAHDRHLKLSSKHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRLTSDSDNEPHTPVNCEQCGMQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSASRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRNRDWKCDDPSIED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441464;
90% Identity: iTF_00449181;
80% Identity: iTF_00123447;