Basic Information

Insect: Apamea epomidion
Gene Symbol: sem-4
Assembly: GCA_947507525.1
Location: OX382254.1:10464142-10489700[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.52 37 5.4 0.2 3 23 123 143 121 143 0.96

2 15 0.0024 0.17 12.8 2.8 1 23 291 313 291 313 0.99

3 15 3.8e-05 0.0027 18.5 0.4 1 23 319 342 319 342 0.97

4 15 0.0048 0.34 11.8 1.6 1 23 347 370 347 370 0.94

5 15 0.0001 0.0072 17.1 0.9 3 23 769 789 768 789 0.98

6 15 0.00025 0.018 15.9 3.2 1 23 795 817 795 817 0.98

7 15 0.64 45 5.2 4.9 1 23 883 905 877 905 0.97

8 15 7.4 5.3e+02 1.8 0.1 2 23 913 934 912 934 0.87

9 15 0.0016 0.12 13.3 2.3 1 23 940 962 940 962 0.96

10 15 0.0043 0.31 12.0 3.0 1 23 968 990 968 990 0.98

11 15 0.35 25 6.0 7.2 1 23 999 1021 999 1021 0.98

12 15 5.9e-05 0.0042 17.9 0.5 2 23 1086 1107 1086 1107 0.97

13 15 0.0089 0.63 11.0 3.8 1 23 1124 1146 1124 1146 0.96

14 15 2.1e-06 0.00015 22.4 0.7 1 23 1152 1174 1152 1174 0.98

15 15 7.2e-07 5.1e-05 23.9 3.1 1 23 1180 1203 1180 1203 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.52	37	5.4	0.2	3	23	123	143	121	143	0.96
2	15	0.0024	0.17	12.8	2.8	1	23	291	313	291	313	0.99
3	15	3.8e-05	0.0027	18.5	0.4	1	23	319	342	319	342	0.97
4	15	0.0048	0.34	11.8	1.6	1	23	347	370	347	370	0.94
5	15	0.0001	0.0072	17.1	0.9	3	23	769	789	768	789	0.98
6	15	0.00025	0.018	15.9	3.2	1	23	795	817	795	817	0.98
7	15	0.64	45	5.2	4.9	1	23	883	905	877	905	0.97
8	15	7.4	5.3e+02	1.8	0.1	2	23	913	934	912	934	0.87
9	15	0.0016	0.12	13.3	2.3	1	23	940	962	940	962	0.96
10	15	0.0043	0.31	12.0	3.0	1	23	968	990	968	990	0.98
11	15	0.35	25	6.0	7.2	1	23	999	1021	999	1021	0.98
12	15	5.9e-05	0.0042	17.9	0.5	2	23	1086	1107	1086	1107	0.97
13	15	0.0089	0.63	11.0	3.8	1	23	1124	1146	1124	1146	0.96
14	15	2.1e-06	0.00015	22.4	0.7	1	23	1152	1174	1152	1174	0.98
15	15	7.2e-07	5.1e-05	23.9	3.1	1	23	1180	1203	1180	1203	0.98

Sequence Information

Coding Sequence: ATGAACCACACGGCTGCCGCAATCCCAGGAAACATGGACATTGATCCGCTGAGCTCTTACGAGTACCCAGCATACGACAGCTATGCTGCCCAGTCCTACCCATACCCCAGCAAGCTCCAGCAGTCCATATACCAGGCATACCAACAAACTAACACCAGCTACAATAACACACAAACGGCACAACCGCAAGAACCATTCACAAATCCACCACCAACATCACAAACTTCAATAGATATTGAAATACCACCTAAGAATGAAGAAACAGACCCAAAACCAGTTTTGAAAAAAAGAAGGAAGGAGAAGAATGGCCAGAAGAGTACTTATTGTTCTGAGAAAATAACGGATGCTACATTCAAGTTCTACGGTTGTTCCGTGTGTAACATTAGTTACAACGCGCTGCACGACCTGGACCAGCATGTGACAGTCCACAAGAACAGAATGACAAGCTATAGACTGCGGTTAAGAAATCAATTTAAAAAGAAACAAATTAAAAAAGAAAAGAAACGGTTAAATAAAAAGATTGTTAAAATTAAGAAAGAAACTGAGTTTGACATTGAAATTAAACCAGAGGATGGTTACATTGGTGAAGAAAAAGCCGCAGATGTTATAAGTAACAGGATTAATCCTGATTCTGAATGTAATGGGAATGTAGATAGTGAAAACAGCGCTATAGAAGCCCAAGATAGTCAAAGTAATAGCAATAATGTCACAAATTCTATTAATAACGACCCGCAAAACTGTGAAACAAACTCTTTGAGTAACGGGAAAGGGAATAATGAAAATAGTGAATTGGAAAACGGAAATAGTGTGAACAGTAAAGATAAAGAGAACAGCATGGACGAAGCAGAGCTAAATAATTTAGAGAAAATTTACAAATGTTTTGCGTGTCAGAAGCAGTTCACTTTGAGCTATTATTTGAAACTACATGTGCGGTCACACACAGACGAGAAGCCCTACACGTGCAGCGTGTGCGGCCAGTCGTTCATCACGGCCAGCAAGCTGGGCCGCCACAACAAGCGCATCCACCTCGCCGAGCGCTACCAGTGCCGCATATGCTTCAAGATATACTCCCGGTTCGAGCTGCTGACGGCTCACTTCGACAAGACGCATCCTGAAGACAAGCTGGAGGGAGAGCCGTATGACTATAACGCGATCCTGCCGTACCTGAAGGAGCTAGAGGAACAGCTCCTCGCGCCCGACCTGGCCGAGCTCGATAACAAGCCTAAATCTGAGGACTTGTTCTGGGAGCAGCACGTGGGCCCGCACCAGCTGGCCGGCACCAAGCCGCCCGCGGATATCAAAGAAGAGattaaaaaaACCACCCTGTGGCAACTCGCCCCCGCGGCATCTCGACTCTGTGGCAACTCGCCACCGCGGCATCTCGACTCTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACCTTGTGGCAACTCGCCCCCGCGGCATCTCGACTCTGTGGCAACTCGCCCCCGCGGCAACTCGAGCCGAAGACGAGGACCAAAAGGATCTGGTGCCGAAACTAGACATACTAATAGAGGAGGTGAAGGTGGACTATGACGTCACGGTCAAGCGCGAGCTGTCGGACGACGAGCCGCCGGCAGACGCGCCGGACGACGCGGACGACGGGCCGGGCGGGGCGCGGGACGGGGCCGACGTCAAGGATGAAGATAGCCAGTCGGACGAGGACTACTTCCCGGCCAACACGTGGGCCGCCCCGCACGCCGCGCCGCCGCGCGCGCCCTCGCCCCGCGGCGCGCGCGCGTGCGGCGTGTGCCACAAGAGCATCAGCACGGCGTCCTACATGCGCGTGCACATGCGCACGCACACGGGCGAGCGGCCCTTCAAGTGCTACACGTGCGGCCGCGGGTTCATCACCAGCAGCAAGATGCACCGCCACGTTCTCACGCACGCGCAAGACAAAGACGATCTCAAGGCGGAAGGAGAAGACACCAAACCGGAAGTGGACGACCTCGCCGCGGACGAGGACCGAAAGCAAGGAGATGGCGCTAAAAAACCAGCGAAAAAAAAATCTAAAATGAAATCGAAGTCGTCAAAGCTGAAGAGTGGCGAGGAGAAGCCGCGCCGCAAGCACCAGAAGAGGCCGCACGCCTGCGAGTACTGCAACCAGAAGTTCCTGCATCTGAACATGCTGGAGGTGCACAGACAGTCGCACGCAGGCGAAGCCCTAGTGCTGCGCTGCCACTACTGCCTCCAGGAGGCGCCCAGCGACGCGGCGCTGCGCGCGCACGAAGCGGAGCACCAGGGGGCCAAGCCCTACCTGTGCACCGTGTGCGGGAAGACCTACAAGAAGAGGGAGACTATGGTGTACCACCGCAAGCGCCACGCGCCGGACAAGGAGTTCGTATGCGACGTGTGCTCCAAGCGCTTCCCGGCCGCCTGCAAGCTGCACAAGCACCTGCTCACGCACCGCCGCGACGCCTTCGTGCTGCGCTACGAGTGTCCCGTGTGCGCGCACATGTTCCACACGCGCTACCACGTGCACATGCACCTCAGCACGCACCAGAAGGAGGGCCTGATCCTAGAAGAGAATCGCAGCGAGATCCTGGCGATGGTCCTCCAGAACGCGCGCAAGATCCCTCGCGCGGGCGCGGGGCCGGCGCCGGGCGCGCCCGCCGCACTCGCCGCGCTCGCCGCGCCCGCCTGCGCGCCGCCCGCGCCCGCGCACGCGCTGCCGCCCGACGAGCGCTCGCGCGTGTGCAACATCTGCGGCGCCGTGTTCTCGCACTTCTACTACCTGGAGGAGCACCTCAAGAGCCACGGCGAGCGCATCGCCATTGCCGACCTCGACAAGCCGGAGGACAAGAAGTACATCTGTCAGATCTGTAACAAAGGCTTCAAGCTGCACTACTACCTCAAACTCCACAGTTTCACGCACTCGAAGGAGAAGCCCTTCATCTGCCAGCAGTGCGGGAAAGGGTTCATCACGAAAGGTAAACTAAAAAGACATCTGGAGACTCACACGGGGCTGAAGAAGTACCAGTGTCACATCTGCTACAAATTCTTCACGCGGCCCAGCTACCTGCGCATACACGTGCGCACGATACACGGCACGCAGGACTATAACTTTAGGTTCGACAAGGGGTACGGACTCGGCTCGCTCGCGCCGCCCGTGGCGATGTCGGATGTCAGTCAGAATAGTATTTAA
Protein Sequence: MNHTAAAIPGNMDIDPLSSYEYPAYDSYAAQSYPYPSKLQQSIYQAYQQTNTSYNNTQTAQPQEPFTNPPPTSQTSIDIEIPPKNEETDPKPVLKKRRKEKNGQKSTYCSEKITDATFKFYGCSVCNISYNALHDLDQHVTVHKNRMTSYRLRLRNQFKKKQIKKEKKRLNKKIVKIKKETEFDIEIKPEDGYIGEEKAADVISNRINPDSECNGNVDSENSAIEAQDSQSNSNNVTNSINNDPQNCETNSLSNGKGNNENSELENGNSVNSKDKENSMDEAELNNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCSVCGQSFITASKLGRHNKRIHLAERYQCRICFKIYSRFELLTAHFDKTHPEDKLEGEPYDYNAILPYLKELEEQLLAPDLAELDNKPKSEDLFWEQHVGPHQLAGTKPPADIKEEIKKTTLWQLAPAASRLCGNSPPRHLDSVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAASRPCGNSPPRHLDLVATRPRGISTLWQLAPAATRAEDEDQKDLVPKLDILIEEVKVDYDVTVKRELSDDEPPADAPDDADDGPGGARDGADVKDEDSQSDEDYFPANTWAAPHAAPPRAPSPRGARACGVCHKSISTASYMRVHMRTHTGERPFKCYTCGRGFITSSKMHRHVLTHAQDKDDLKAEGEDTKPEVDDLAADEDRKQGDGAKKPAKKKSKMKSKSSKLKSGEEKPRRKHQKRPHACEYCNQKFLHLNMLEVHRQSHAGEALVLRCHYCLQEAPSDAALRAHEAEHQGAKPYLCTVCGKTYKKRETMVYHRKRHAPDKEFVCDVCSKRFPAACKLHKHLLTHRRDAFVLRYECPVCAHMFHTRYHVHMHLSTHQKEGLILEENRSEILAMVLQNARKIPRAGAGPAPGAPAALAALAAPACAPPAPAHALPPDERSRVCNICGAVFSHFYYLEEHLKSHGERIAIADLDKPEDKKYICQICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRFDKGYGLGSLAPPVAMSDVSQNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -