Aanc004961.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apamea anceps
Gene Symbol
Mtf1
Assembly
GCA_951799955.1
Location
OX637503.1:17943992-17963425[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 8.8e-06 0.00074 20.7 0.8 1 23 113 137 113 137 0.99
2 7 0.0016 0.14 13.5 0.4 1 23 143 167 143 167 0.98
3 7 0.00049 0.041 15.2 0.4 1 23 173 197 173 197 0.96
4 7 1.4e-06 0.00012 23.2 1.3 1 23 202 226 202 226 0.97
5 7 3.2e-05 0.0027 18.9 3.5 1 23 232 256 232 256 0.98
6 7 0.0015 0.13 13.6 0.2 3 23 264 286 262 286 0.89
7 7 5.3 4.5e+02 2.5 2.6 2 23 665 688 664 688 0.93

Sequence Information

Coding Sequence
ATGGCCGCATGGCTCGGTGACAGCGGCCGTTTCGatatctctatacaaaacactTTTAAACCCTTTACTATTGGGCATTATTCAATCGATAATAACACAGATTTAAAATACCTTGACTTGGATAGTAAGTTTGATAATTTTCAAGTGCGTAATTACGACGAAAAAGCTCCTGAAAGTAGCGTGACGTCGGAAAGCAAAATAATTCCCAAGGACAAAAACACAGAAAATCTTATTGGATTTTCGcttcatgATGACACAGTATCGGATACACAAAACTCGGACATCACATCTAACATGGATAAGAGCAAAAGGAAACAAGAAGACTGCAGCGCGAGGTACAAATGTGAATATGAGGGTTGTGAACGCACATACAGCACTGTTGGAAACCTGCGCACACACATGAAAACACACAAGGgTGAATACAGGTTCAAATGTCCTATGCAATCGTGTGAGAAAGCATTTCTGACGTCATACAGTCTGAAGATTCACATACGCGCGCATACGAAGGCGAAACCCTTCGCTTGTACCATTGTCGGCTGCAGGAAAGCCTTCAATACTTTGTACAGGTTAAGGGCACATCAACGACTGCACAGCGGCGACACATTCAACTGCAACGCGGATGGATGTACGAAGTTCTTCACGACACTCAGCGATCTAAAGAAACACATACGAACACATACACAGGAGAGGCCATACAAATGTCGAACAGAAGGCTGCGGCAAGTCGTTcaccgcatcgcatcacctCAAGGCGCACGGTCGCACGCATTCGGGCGCGCGGCCGCATGCGTGCGCAGAGCCCGGCTGCGGGCGACTGTTCTCTACCGCGACGAGTCTTAAGGCACATGCGATGAAGCATCAGATAAAAGCCGAGCCGATAGTCAACAAAGAAGTTATTGAACCTGTCCAAAAGCCAACACAAACACCAGCGATAAAAACGGCCGACGACCTCATGAACTGGGACAGTCTCCTCGAATCCTTCGGCAGAATCACGACAGAATCCAACTCCACCGATGGCAGTCTAGAGGACATCACGAAAGGCAACTCCGTCGATATTACCGAACTACTCTTCCCAGACAATACTCACACCATTAAAAATATCGAACCTGAAGATTTAGCTGTAGACTACGACTTGGCCAGCCTCTCCCTTTCGCCATTCGCCGTCGAAAAGACTGAACAGAAACACCCTCACGAAGAGTCTTGGGTTGATGTCAACGATTTACAACCAACAGTGCCTTTGCAATCGCATTCAATAGAGATAGGACATCCTAAATTAGAAGTTAAGCCTAAAGCGATGCAACTAGCTTTAGCTAATGAAATCGAAGACCAAGCCCCGTGGGTAGACGTCAGCGCTCTAGCGGCTTCAATATCAGAAACACCAGTTTGCATCGAAGAAAAAACCCCGGAAAGCATTTTCACACTAGCGACCTTCGTCCCCACTCATATGCAGAGCTACATAGACCTGAATATAGAAGTTGCACCAACCGCGAATCTTATAACCCACGACTCGTTCAATTTAGATACTCCAAGTGTACTAGATGTCGGCGACAAAGTGTTCAACGATAGTgaaatagttataaataaaattgataccgacatagatttatttttagggtCTGATGATGACAGATCTCTGAATACTCCACCCCCATCCAGAGTGCAGCACAACATCGAAATAAACCCGGCAAACTCAGTCCTCTTCAACACTGACTTAGATTTGGAAGACACATTATTGTTTGATAATGAACCACCCTCTGATATGTATGTGGTGAGGACTGAGAATATATTTGGTAAAGTGGCGAAAAGAAATACTCTGGAGCAGTTGGCAGCTGACTCTGGCATTTGTTCGTGTTCAGATTGCAAATGTGATCCGAATCAAGGAGAGTGCAGAAACTGTATGGGCACAATTGAACCCGATGATCCTCCTAAGAAGCAAGGCTGCGGCGAGGATACTTGCTCCTGCGTCGATTGTAAATGTGATCATGCACAGATGAAGTGCGCAGTGGGGTGCGGCCAGGCGACCGACACGAACCACAACACATTCTTGCATTACCATAGACGACACAACAATTCAAACTTGGAAGATTTAGGAATTTTCACGGTTCACGAATGCGACGACAGTCTAGAATCGTCAGCGCTGGTGAAAAGTTTGTCATGTTCGTGTAGCTCCTACGCAGAACCTAATGACAAATGCGATCGAAAAGTGGAAAATAAATCGTGTTGCAGTGAGAAAAAGTCGGCTAGTGATGAGAAAGCTTCGAGCTGTAGCTCAAAAGTGACCAGTTCCGATGATAAGTCGTGTTGTGACACAAAGCCGCCGACTGGCGAAAAGGAAGCATGTTGTGGAGGTAACAAGTCATGTTGCGTTACAATATGTTTCAAGAAACTTGACGCGTTCAAACAATTTCTTTCTGACAACGACCTTATCCACACGTTGAAAACGCATAATTTTAACCTAACAACAAGTTAA
Protein Sequence
MAAWLGDSGRFDISIQNTFKPFTIGHYSIDNNTDLKYLDLDSKFDNFQVRNYDEKAPESSVTSESKIIPKDKNTENLIGFSLHDDTVSDTQNSDITSNMDKSKRKQEDCSARYKCEYEGCERTYSTVGNLRTHMKTHKGEYRFKCPMQSCEKAFLTSYSLKIHIRAHTKAKPFACTIVGCRKAFNTLYRLRAHQRLHSGDTFNCNADGCTKFFTTLSDLKKHIRTHTQERPYKCRTEGCGKSFTASHHLKAHGRTHSGARPHACAEPGCGRLFSTATSLKAHAMKHQIKAEPIVNKEVIEPVQKPTQTPAIKTADDLMNWDSLLESFGRITTESNSTDGSLEDITKGNSVDITELLFPDNTHTIKNIEPEDLAVDYDLASLSLSPFAVEKTEQKHPHEESWVDVNDLQPTVPLQSHSIEIGHPKLEVKPKAMQLALANEIEDQAPWVDVSALAASISETPVCIEEKTPESIFTLATFVPTHMQSYIDLNIEVAPTANLITHDSFNLDTPSVLDVGDKVFNDSEIVINKIDTDIDLFLGSDDDRSLNTPPPSRVQHNIEINPANSVLFNTDLDLEDTLLFDNEPPSDMYVVRTENIFGKVAKRNTLEQLAADSGICSCSDCKCDPNQGECRNCMGTIEPDDPPKKQGCGEDTCSCVDCKCDHAQMKCAVGCGQATDTNHNTFLHYHRRHNNSNLEDLGIFTVHECDDSLESSALVKSLSCSCSSYAEPNDKCDRKVENKSCCSEKKSASDEKASSCSSKVTSSDDKSCCDTKPPTGEKEACCGGNKSCCVTICFKKLDAFKQFLSDNDLIHTLKTHNFNLTTS