Basic Information

Insect: Antitype chi
Gene Symbol: ZNF219
Assembly: GCA_947359405.1
Location: OX375817.1:1351525-1369435[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0014 0.11 13.4 3.0 1 23 395 418 395 418 0.96

2 7 0.00079 0.063 14.2 3.3 1 23 563 585 563 585 0.98

3 7 0.00021 0.016 16.1 0.2 2 23 591 612 590 612 0.96

4 7 4.6e-06 0.00036 21.3 0.5 1 23 618 641 618 641 0.93

5 7 3.7e-07 2.9e-05 24.7 1.4 1 23 647 669 647 669 0.99

6 7 1.3e-05 0.001 19.8 3.3 1 23 675 697 675 697 0.99

7 7 1.2e-05 0.00092 20.0 2.9 1 23 703 725 703 725 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0014	0.11	13.4	3.0	1	23	395	418	395	418	0.96
2	7	0.00079	0.063	14.2	3.3	1	23	563	585	563	585	0.98
3	7	0.00021	0.016	16.1	0.2	2	23	591	612	590	612	0.96
4	7	4.6e-06	0.00036	21.3	0.5	1	23	618	641	618	641	0.93
5	7	3.7e-07	2.9e-05	24.7	1.4	1	23	647	669	647	669	0.99
6	7	1.3e-05	0.001	19.8	3.3	1	23	675	697	675	697	0.99
7	7	1.2e-05	0.00092	20.0	2.9	1	23	703	725	703	725	0.97

Sequence Information

Coding Sequence: ATGGATGATGAAACCGTCACACACTATATAACTTCGCACCCAGCTGATCAGACTGTTCATGTGGATGGCAATGCCCTGGCCCTCAATGTGCAGGATGACGGGGGTGGCAGAGTGGCCATCATGCATTCACAGACCTACTCCACATCACTATGCAGGCAAGTCTCAGTGGGTGACCATGTGGTGGAAGGACAATGGAGTGATGAGATCATGGACCCAGAAGGCAGGCTGGCAGCACTTATGGCCCACATCACGGCCCAACAGTCTAGAGGGCAACAACAACTGCACCATAAGGTGCATACAGTGAGGGGTGATGTGGACACATCTATTATACTGGATAGTCCCATGAGACTCTACCATGGTCAGCCAATGGATCAGTCACAAGAACCAATAGTGGTGGAGGTCCCGCCCCTGCCGCCGCTCCCTCCCCTGCAGGACATGAAGCGCTGTCAGGAAAACGACTGGTTCAATAAGAATAAATCAGCACTCAAAGATGATTCTTCAATGATAGACTCTGATGGGCCGGTGTTAGACCTCGGCCCGGGAGCGTCGCCAGGACAGCACAAACTGCAAAGCAAGAAGAGTCTTCCACACAAGAAAAGGATATCTAGGAAGCTCAAGAAGAATAATGGGAACTGTACTCCTCAGCAGGATATAGTGGTGATTAGTTGCACGGACGTCGAAGGTCGCATCAGCTGCGTGGACCACGGCCAGGAGCAGGAGATCCTGCCAGATAACTTTGTGCCGCAGGAGCACATGCCGGTCGAGACGCATCATATTACACATGAGGTCCGTCCGATCTTGATCTGCCAGCTGTGCGGCGAGTTCTACGGCGAGGACCAGCTGAAGTTCTACCAGCACTTGAAGCAGCACTACGAGCCGCACATCATCATAGAGAACCCCGTGCAAGACCTGGGAATTGATAAGATGACCAACTCCTGCATCGTAGATAACGTAGCAACAATTCCCGACTCGATAGTAGAACTGTCTCTAGAAAATTCCATACCAAAAACGATATACCAATCAATGGACAAGCACGTCTTATACACGACAAGCGATAAAACGTTCACGTACGCTAACAATAAGCTTCAGTATTCTATGGCAAGTATGGACAAGGAACCGCCGACGGTAGTTCAAGAGGCTGAGAAGGCGGATTTGTACGATACTCTGGATAAACTGGATTTGTATAGCTGTGGGAAGTGTAACAAGTCTTTTAGGAAGCAGAAGCAATGTGAAGCACATATCAAGGAGGCGCATTCTAATATGAAGTTGGAAGACATGGGTGAATTCAGCGAGCCTGAGGACCTGATGGAGGGCATCCACGTGGCGGTGGACGAGCCGCCCGAGCACTACGAGCACACGCTGCTGCCGCATCTCACTGTGGAGAACGGGCACGCGCACCAGGACAACGTGCGGCACTGGTACGCGCGCGCGACGGGCGGCGCGGCGTGCTGCGCGGCCTGCGCAGGCGCACCGCACGACGCGCAACACCTCAGGCTGCTCAAAGACGAAGTCCTCCGACGAATCTTAGAAACAGATGTAGCGTCCGACAATCAGAACTTCACCGATAGCACGATGACTGACACCGCCGACACGGCCGACACACCCGACACCCCTGACACCCCCGACCTGCCGGCCGACGAGCCGCCGCCCGACGACAAGTCGGATGATAAAAAGAAACAGAAGCGGTTTGAATGCCAGCAGTGCCAGCGAGTGTTCCAGCACAGGAACAGTCTCCTGTACCACATGCTGTCGCACAGCGGCAAGCAGCAGATGTGTCGCGAGTGCGGGAAGGGGTTCTACACTGTCGCCGCGCTCAAGATACACAAGCGCGTGCACAACGGCGACCGTCCCTACAAGTGCGACGTGTGCGGGCGAGACTTCCGCCAGTGGAGCGACCTCAAGTACCACAAGGTGTCCATACATTCCGACCAGAAAATGTTCAAATGCGAGTTCTGCGGCAAGGAGTTCGCGCGCAAGTACTCGCTGAACGTGCACCGCCGCATACACACGGGCGAGCGCAACTACAAGTGCGACTACTGCAACAAGACCTTCCGCGCCTCCTCCTACAGGCTCAGCCACATGCGCACGCACACCGGAGACCGGCCCCACAAGTGCTCGCAGTGCGACAAGTGCTTCCGCGTGGCCGGCGACCTGCGCCGACACGTGCTCATACACGACAAGGTCAGGAACAGACTCACCGAGCACAAGGCCAAGCTCAAAGACATCAAGGAAGACAAGAAACCACTCGCCAAAATAGCAGAAAAACATCATCTCAACATCAAAATTGAAGACCCCGTAGTTTCTAAAAACATTAAAAAGATCGCCCTCGCTTCCACCACCAAAACACCCAACATTCTCAGAACTATTCTCACGACTGATAAGAAAAAACCTGCTAAAAAGAACCAGAGCGTCAAGAAAGGAGCGCCCAACGTTACCTTAGACCAACTGGACAACAGCTACACCAACAATGTACAGGTATTCGACACGCGGCAGGACTCCTACAGCAAACTGAACGTTGCGTCTGTTAAAGAGATGTACAGCGACGCTAATTACAAGCAGGAATTAGATAACTCATTCACTAAAGAAATTATAACTCAATACAAAAATGAAGAAACAGAGGAGAGAGATTTCGCGATACTTAGACCGATGTTTAGGAACAGCGTGTTGTGTGACACGGTGGCGCCCGACCAGGCTGTGTTCCGGACTGAGAACACTGACGGCAAGATGCAAGTGTACACACACATAGAGAAGAACAACACTACAGTTCCTAACTCTCAAGTTTCACTAAACGACATGCGTCACTTAGAGCCACAAACCACAGAGAACGGTTTCATAGAGAGACTTACAGCGTTATACAATATACCCGCTGTATGA
Protein Sequence: MDDETVTHYITSHPADQTVHVDGNALALNVQDDGGGRVAIMHSQTYSTSLCRQVSVGDHVVEGQWSDEIMDPEGRLAALMAHITAQQSRGQQQLHHKVHTVRGDVDTSIILDSPMRLYHGQPMDQSQEPIVVEVPPLPPLPPLQDMKRCQENDWFNKNKSALKDDSSMIDSDGPVLDLGPGASPGQHKLQSKKSLPHKKRISRKLKKNNGNCTPQQDIVVISCTDVEGRISCVDHGQEQEILPDNFVPQEHMPVETHHITHEVRPILICQLCGEFYGEDQLKFYQHLKQHYEPHIIIENPVQDLGIDKMTNSCIVDNVATIPDSIVELSLENSIPKTIYQSMDKHVLYTTSDKTFTYANNKLQYSMASMDKEPPTVVQEAEKADLYDTLDKLDLYSCGKCNKSFRKQKQCEAHIKEAHSNMKLEDMGEFSEPEDLMEGIHVAVDEPPEHYEHTLLPHLTVENGHAHQDNVRHWYARATGGAACCAACAGAPHDAQHLRLLKDEVLRRILETDVASDNQNFTDSTMTDTADTADTPDTPDTPDLPADEPPPDDKSDDKKKQKRFECQQCQRVFQHRNSLLYHMLSHSGKQQMCRECGKGFYTVAALKIHKRVHNGDRPYKCDVCGRDFRQWSDLKYHKVSIHSDQKMFKCEFCGKEFARKYSLNVHRRIHTGERNYKCDYCNKTFRASSYRLSHMRTHTGDRPHKCSQCDKCFRVAGDLRRHVLIHDKVRNRLTEHKAKLKDIKEDKKPLAKIAEKHHLNIKIEDPVVSKNIKKIALASTTKTPNILRTILTTDKKKPAKKNQSVKKGAPNVTLDQLDNSYTNNVQVFDTRQDSYSKLNVASVKEMYSDANYKQELDNSFTKEIITQYKNEETEERDFAILRPMFRNSVLCDTVAPDQAVFRTENTDGKMQVYTHIEKNNTTVPNSQVSLNDMRHLEPQTTENGFIERLTALYNIPAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00908231;
90% Identity: iTF_00908231;
80% Identity: -