Basic Information

Insect: Antitype chi
Gene Symbol: ZNF296
Assembly: GCA_947359405.1
Location: OX375834.1:12613963-12632796[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.37 30 5.8 0.2 3 23 123 143 121 143 0.96

2 15 0.0017 0.14 13.1 2.8 1 23 256 278 256 278 0.99

3 15 2.7e-05 0.0021 18.8 0.4 1 23 284 307 284 307 0.97

4 15 0.0034 0.27 12.2 1.6 1 23 312 335 312 335 0.94

5 15 0.00011 0.0083 17.0 0.8 3 23 498 518 497 518 0.98

6 15 0.00018 0.014 16.2 3.2 1 23 524 546 524 546 0.98

7 15 0.5 39 5.4 5.0 1 23 612 634 605 634 0.97

8 15 3 2.4e+02 3.0 0.1 2 23 642 663 641 663 0.89

9 15 0.0012 0.092 13.7 2.3 1 23 669 691 669 691 0.96

10 15 0.0031 0.25 12.3 3.0 1 23 697 719 697 719 0.98

11 15 0.25 20 6.3 7.2 1 23 728 750 728 750 0.98

12 15 4.2e-05 0.0033 18.2 0.5 2 23 821 842 821 842 0.97

13 15 0.0064 0.51 11.4 3.8 1 23 859 881 859 881 0.96

14 15 1.5e-06 0.00012 22.8 0.7 1 23 887 909 887 909 0.98

15 15 5.2e-07 4.1e-05 24.2 3.1 1 23 915 938 915 938 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.37	30	5.8	0.2	3	23	123	143	121	143	0.96
2	15	0.0017	0.14	13.1	2.8	1	23	256	278	256	278	0.99
3	15	2.7e-05	0.0021	18.8	0.4	1	23	284	307	284	307	0.97
4	15	0.0034	0.27	12.2	1.6	1	23	312	335	312	335	0.94
5	15	0.00011	0.0083	17.0	0.8	3	23	498	518	497	518	0.98
6	15	0.00018	0.014	16.2	3.2	1	23	524	546	524	546	0.98
7	15	0.5	39	5.4	5.0	1	23	612	634	605	634	0.97
8	15	3	2.4e+02	3.0	0.1	2	23	642	663	641	663	0.89
9	15	0.0012	0.092	13.7	2.3	1	23	669	691	669	691	0.96
10	15	0.0031	0.25	12.3	3.0	1	23	697	719	697	719	0.98
11	15	0.25	20	6.3	7.2	1	23	728	750	728	750	0.98
12	15	4.2e-05	0.0033	18.2	0.5	2	23	821	842	821	842	0.97
13	15	0.0064	0.51	11.4	3.8	1	23	859	881	859	881	0.96
14	15	1.5e-06	0.00012	22.8	0.7	1	23	887	909	887	909	0.98
15	15	5.2e-07	4.1e-05	24.2	3.1	1	23	915	938	915	938	0.98

Sequence Information

Coding Sequence: ATGAACCATACAGCAGCCGCGATACCAGGAAACATGGATGTTGATCCGCTGAGCTCATATGAGTACCCAGCGTATGACAGCTATGCTGCCCAGTCCTACCCGTACCCCAGCAAGCTACAGCAGTCCATCTATCAGGCTTACCAACAAACTAACACCAACTACAATAATACACAACCAGTCCAACCGCAAGAACCGTTCAACAATCCACCACCAACATCACAAACAACCGTTGATATTGAATTACCACCTAAAACTGCTGATACGGAACCAAAACCAGTACTTAAAAAGAGACGGAAGGAGAAGAATGGCCAGAAGAGTACTTATTGTTCTGAGAAGATAACGGATGCTGCGTTCAAGTTTTACGGTTGTTCCGTCTGTAACATCAGTTACAATGCATTGCACGACCTGGACCAGCATGTGACCGTTCACAAGAACAGAATGACTAGCTATAGATTGCGGTTAAGAAATCAATTTAAAAAGAAACAAATTAAGAAAGAAAAGAAAAGATTAAATAAAAAGATGGTTAAAATTAAGAAAGAAATTATTTTAGACATTGAAATAAAGCCAGAGGATGGTTATATTGGTGAAGAAAAAGCAACAGATGTTATTAGTAATGGGATCAATCCTGATTCTGAATGTAATGGAAACGTAGATAGTGGAAACGGTGCAATAGAAGTCCAAAATAGTCAAATTAATAACAATAATGCCACGAATTCTATTAATAATGACCCACAGACTAGTGAAACAAAGTCTTTGAAGAAAATTTACAAATGTTTTGCTTGTCAAAAGCAGTTTACTTTGAGCTATTATTTAAAACTACACGTGAGATCACACACAGACGAGAAGCCCTACACGTGTAGCGTGTGCGGCCAGTCGTTCATCACAGCCAGCAAGTTGGGGCGCCACAACAAGAGGATCCACCTCGCCGAGCGCTACCAGTGCCGCATATGCTTCAAGATATACTCCCGGTTTGAACTTCTGACGGCACATTTCGACAAAACGCATCCTGAAGACAAGTTGGAGGGAGAGCCGTATGACTACAACGCGATCCTGCCGTACCTGAAGGAGCTGGAGGAACAGCTGCTGGCGCCCGGCCTGGCCCCGCTGGACAGCAGGCCCGCGCCGGCCGGGCTGTGCTGGGAGCGGCACGTGGGCCCGGCGGCGCCGCCCAAGGACATCAAACAAGAGGCCCAAGACGAGGACCAAAAGGAGCTGGTGCCGAAGCTGGACATACTCATAGAGGAGGTGAAGGTGGACTTCGACGTCACCGTCAAGAGCGAGCTGCCCGACGATGCGCCGCCGGGGGACGCGCCGGGGGACGCGGGGGATGCGCTGGGTGACGAGCCGGGGGACGGGGTGGATGACGGGATGGATGTCAAGGATGAAGATAGCCAGTCCGACGAGGACTACTTCCCGTCCAACACGTGGGCGGCGCCGCACGCCACGCCCCCGCGCGCGTCGCCCCCGCCCACGCGGCGCGGGGCCGGCGCGTGCGCAGTGTGCCACAAGAGCATCAGCACGGCCTCCTACATGCGCGTGCACATGCGCACGCACACGGGCGAGCGGCCCTTCAAGTGCTACACGTGCGGCCGTGGCTTCATCACTAGCAGCAAGATGCATCGACACGTGCTCACGCATGCGCAAGACAAAGATGATGTCAAGACGGAAGGAGAAGACACCAAACCGGAAGTGGACGACAACTCCGTGGACGAGGACCAACAGCAAGGAGACGGCGCTAAGAAACCAGCGAAGAAAAAATCTAAAATGAAATTGAAGTCTTCAAAGCTGAAGAGTGTCGAGGAGAAGCCGCGCCGCAAGCACCAGAAGAGGCCGCACGCCTGCGAGTACTGCAACCAGAAGTTCCTGCACCTGAACATGCTGGAGGTGCACCGCCAGTCGCACGCGGGCGAAGCCCTAGTGCTGCGCTGCCACTACTGCCTGCAGGAGGCGCCCAGCGACGACGCGCTGCGGGCGCACGAGGCGGAGCACCAGGGGGCCAAGCCCTACCTGTGCACCGTGTGCGGGAAGACCTACAAGAAGCGGGAGACTATGGTGTACCACCGCAAGCGCCACGCGCCCGACAAGGAGTTCGTGTGCGACGTGTGCTCCAAGCGCTTCCCGGCCGCCTGCAAGCTGCACAAGCACTTGCTCACGCACCGCCGCGACGCCTTCGTGCTGCGCTACGAGTGTCCCGTCTGCGCGCACATGTTCCACACGCGCTACCACGTGCACATGCACCTCAGCACGCACCAGAAGGAGGGCCTGATCTTGGAAGAGAATCGCAACGAGATCTTGGCGATGGTTCTACAGAACGCGCGCAAGATACCGCGCGCAGGAGCCGCGAACACCGCGCACGCGCCGCACGCGCGCGACACGTCGCACGACGCGCGCGACGCGCACGACGCGCACGACGCGCACGACGCGCACGCGCCCGCCCTGCCGCCCGACGAGCGCTCGCGCGTGTGCAACATCTGCGGCGCCGTGTTCTCGCACTTCTACTACCTCGAGGAGCACCTCAAGAGTCACGGCGAGCGCATCGCCGTCGCCGACCTCGACAAGCCGGAAGATAAGAAATACATCTGTCAGATCTGTAATAAAGGCTTCAAGCTACACTACTACCTCAAGCTGCACAGCTTCACGCATTCGAAGGAGAAGCCCTTCATCTGCCAACAGTGCGGGAAGGGATTCATCACGAAAGGTAAATTGAAGAGACATCTGGAGACTCACACGGGCCTGAAGAAGTACCAGTGTCACATCTGCTACAAGTTCTTCACGCGGCCCAGCTACCTGCGCATCCACGTGCGCACCATCCACGGCACGCAGGACTACAACTTCAGGTTCGACAAGGGCTACGGCCTGGGCGCGCTGGCGGCCTCGGCCGTGACGGGGTCGGGTGCCAGTCAAAATAGTATTTAG
Protein Sequence: MNHTAAAIPGNMDVDPLSSYEYPAYDSYAAQSYPYPSKLQQSIYQAYQQTNTNYNNTQPVQPQEPFNNPPPTSQTTVDIELPPKTADTEPKPVLKKRRKEKNGQKSTYCSEKITDAAFKFYGCSVCNISYNALHDLDQHVTVHKNRMTSYRLRLRNQFKKKQIKKEKKRLNKKMVKIKKEIILDIEIKPEDGYIGEEKATDVISNGINPDSECNGNVDSGNGAIEVQNSQINNNNATNSINNDPQTSETKSLKKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCSVCGQSFITASKLGRHNKRIHLAERYQCRICFKIYSRFELLTAHFDKTHPEDKLEGEPYDYNAILPYLKELEEQLLAPGLAPLDSRPAPAGLCWERHVGPAAPPKDIKQEAQDEDQKELVPKLDILIEEVKVDFDVTVKSELPDDAPPGDAPGDAGDALGDEPGDGVDDGMDVKDEDSQSDEDYFPSNTWAAPHATPPRASPPPTRRGAGACAVCHKSISTASYMRVHMRTHTGERPFKCYTCGRGFITSSKMHRHVLTHAQDKDDVKTEGEDTKPEVDDNSVDEDQQQGDGAKKPAKKKSKMKLKSSKLKSVEEKPRRKHQKRPHACEYCNQKFLHLNMLEVHRQSHAGEALVLRCHYCLQEAPSDDALRAHEAEHQGAKPYLCTVCGKTYKKRETMVYHRKRHAPDKEFVCDVCSKRFPAACKLHKHLLTHRRDAFVLRYECPVCAHMFHTRYHVHMHLSTHQKEGLILEENRNEILAMVLQNARKIPRAGAANTAHAPHARDTSHDARDAHDAHDAHDAHAPALPPDERSRVCNICGAVFSHFYYLEEHLKSHGERIAVADLDKPEDKKYICQICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRFDKGYGLGALAASAVTGSGASQNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00121693;
90% Identity: -
80% Identity: -