Basic Information

Insect: Anthrax anthrax
Gene Symbol: MAPk-Ak2
Assembly: GCA_963971155.1
Location: OZ020121.1:16110637-16123523[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00038 0.018 16.3 0.5 3 23 336 359 334 359 0.94

2 5 0.23 11 7.6 0.2 1 23 367 394 367 394 0.84

3 5 0.043 2.1 9.8 5.0 1 23 400 424 400 424 0.97

4 5 0.00072 0.035 15.4 0.4 1 23 430 455 430 455 0.97

5 5 1.7e-05 0.00081 20.5 0.3 1 23 461 486 461 486 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00038	0.018	16.3	0.5	3	23	336	359	334	359	0.94
2	5	0.23	11	7.6	0.2	1	23	367	394	367	394	0.84
3	5	0.043	2.1	9.8	5.0	1	23	400	424	400	424	0.97
4	5	0.00072	0.035	15.4	0.4	1	23	430	455	430	455	0.97
5	5	1.7e-05	0.00081	20.5	0.3	1	23	461	486	461	486	0.97

Sequence Information

Coding Sequence: ATGAGATCAGTTGGGTTTTATGATTTAAATTGGTATTTTAATTTGACAAACAGCTCAAGTTATTCGGAACTGCAGTTTTTAGCATCGAGACGTGCTGCAGCAGTTGCAGCTGCCGCAACAGTTTTACCTCCACCACCGCCACCTCCTCCGCCACCTCCGCCACCACCATCTGCTGGAAATCAGCCGCCTGGTGTTCCTCCGCCTCCACCTCAGCCACATGATTTTCATCCAGCATACAGGATTCCGGGCTACATGGAGCATCTGTATTCATTACAGCATGCCAGTCCATCGGCGTCATTGCACGGGTTCGGCATTAATTCTGATTACTTAGGAGCAAGAGGTGGTCCACTAAGTGACATGCATCCACCTAGTTCTTTAGCCAGTACTGACTTTCATTTTAGCATAGACGGATCTCGTTTAAACAGTCCACGTCCAGGTAGCATACGAGCTAGTGTCAGTAGAAAACGTGCCCTTTCATCTTCACCATTTTCTGATTCCTTTGACATTAATTCTATGATACGTTTCTCTCCGAATTCTTTGGCTACGATTGTAAATGGTTCAAGAAATAGTAGCACTAGTGGATCATATGGGCATTTATCAGCGGGTACTATGAGTCCTGCGTTAGGTATGCATACAGGAATGGCACCTCATCTTCAACAACTGCAAGCACATTTACTAAGAGCTGGTGCTGGATTATTACATCCATTACCACCACATCATACTCCACCAACTGCAAGTATGTTTTCATTGGGACACCATCCTTTACAATCTGCAAGCTCTATGTCAAAACCATCTCATATGGATGATCCTTCAAAAAAGCCAGAAATGCCTTCGTCTAGTTCAGTTGTTGCTCAAGTTGAAGCTGATAGTGCTTCAAATGCTATGGCTAGACGTGGACGTTGTAAACGCGATTCCATTTCAACAACAACGCATAATGAAGGAGAAAATCCAACAGTTGATACAACAGATATAAAAGATGAACCAGGAGATTTTATAGAAACAAACTGTCATTGGCGCGATTGTGGAATAGAGTTTACAACACAAGAGGAATTAGTGAAACATATAAATAACGATCATATACAAGctaacaaaaaatcctttgtGTGTAGATGGGAAGATTGTTCCAGAGAAGAAAAACCTTTCAAAGCGCAGTATATGTTAGTGGTTCATATGCGTCGTCATACTGGTGAAAAGCCTCATAAGTGCACATTTGAAGGATGCTGTAAAGCTTATTCTCGTCTGGAGAATTTGAAAACACATCTTCGATCACACACTGGAGAAAAACCGTATACTTGTGAGTATCCTGGTTGTAGCAAAGCTTTTAGTAATGCTTCCGATAGAGCTAAACATCAAAATCGTACACACAGTAATGAGAAACCGTATGTTTGTAAAGCACCAGGTTGTACAAAACGTTACACAGATCCCAGTTCGCTTCGAAAACATGTTAAAACAGTTCATGGTGTCGAATtttatgcaaataaaaaacacaaagGATCATCACATGATACTGGAAACGATGAGGGAGGTAACCAACATCACACTGGATTTGATTCAAGTCCAAGAAGTGAAGACATGCATTCAGGAAAAACAGCCAGTTTATCAAGTCCTAGTATTAAATCTGAATCAGAAGCAAATTCTCCAAGTCAACCTCCAGTTAATAGTCCAATGGGGGTTTCACATTTGATAAATGGTGGTCATGAAGATTTCGATTGTTCTCCAAATGTTGTTGCAACACCTTTAGGAACAAATGTATCAGCTATCGATGATCCATCTTGGCCATATGAAGATGAAGACCTAGAAGTTGCAGATTTACCAGTTGTTTTAAGAGCAATGGTTGGAATTGGTGGACCTCCTGGAACAGGAAATGGTGGTGGACAATCGGCAACAATTTCGAATCCCCGTAATAGATTCAGGAGTCGTCTTCAGGCAAAATCGATAAACGCTCTTTCCAATATTCCTGAGATTAATAGATGTAACTTAGGAATTGGTGAATTAAATCAAAGAATAACAGAACTCAAGATGGAACCTGGCATACCAATGCCACCAAAAACAATTCAACCACAAAATCCTAATACACAGTTGACTGATTTGCAATTACGTTTACAACCGCCGAATACAAATGGTCAAAATCAAATGATTCGTCGTGATAGTAATAATTCAAACGCAAGTACCTATTACTGTAGTATGAGATCAGCTGATGTTAGTCGAAGGAGCAGTCAGACTTCTCAGTTGTCATCGATCTCAACGATGCGTCCAAGCGGTTATAATTCATCCTCATTCTATGATCCTATTTCGCCAGGATGTTCAAGACGATCTAGTCAGATGTCTATGACTACAACTGGTGGCCAAAGTTTACCACCACCACCTTCTTCACATTTAATTTCCTCCCATTTGCAGAGATTACAGGGAACAAACAATTCAGGTCGGCACTCCATACCTAATATTCCAACACAGCCATTCAACACAACAAATTTGCATCGTAATGATAGACGTCAATCTGAGCCAGTAAATCAAAGCTACGACAGAATGCTTTTATCTCCTCTCCCTTTGCAACCACTTTCACCTTCTAAATCTGCAAAACCAGCTGGTGCCAATGCATTAGTTTCTAGAAATACAGCTCGTGATCATCATCCTAATGAAGAAGTTGTGCTTGACGAAGTTGAAGAGGGTGAAATGGTTGAAAACAAATTGGTTATTCCAGATGAAATGTTACAATATCTGAATCAAATTAGAGAAAGAATAACAAAGCAAATAAGAAATATTAGTCAAAGGACAATGTTTAATCAAAATGCTACAGGAGGGGGTGGAGGTGGTGGTGGAGGAATAGTAGCAAGTGGTGACAATAATCAACAAAATCAAAGGAATCCAAAAGAAACACCAATTATAAATGACTATGAAATTTCAAGTACAGTGCTAGGATTGGGAATTAATGGAAAAGTTGTGCAATGCACAAATAAAAAGACTGGTGTTAAATACGCTTTAAAGGTTCTTTTGGATAATCCAAAAGCTAGACGTGAAGTTGATCTTCATTGGCGTGCTAGCGGTTGCCGGTATATTGTTAATATAATTGATGTTTATGAGAATACTTATAGCGGGAATAAATGTTTACTTGTTATTATGGAATGTATGGAAGGTGGTGAGTTATTTCAACGAATACAAGACAGGCAAGATGGAGCATTTACAGAAAGAGAAGCTGCACAAATTATGCATGAAATATGTGTTGCCGTACATTATTTACATTCAATGAATATAGCACATCGTGATTTAAAACCAGAAAATTTGTTATATACAACACCAGATGCTAATGCGATATTAAAATTAACTGATTTTGGATTTGCTAAAGAGACATTCATTAAAGATACGTTACAAACACCATGTTATACACCATATTATGTTGCACCTGAAGTGCTTGGTCctgaaaaatatgataaaagTTGTGATATATGGTCACTTGGTgttattatgtacatattattatgtgGTTTCCCACCATTTTATAGTAATCACGGTTTAGCAATATCACCTGGTATGAAAAAACGTATACGCACCGGACAATATGATTTCCCAGATCCAGAATGGAAAAATGTTAGTAAATCAGCTAAAGATTTAATTAAAGGTATGCTTAATGTTGATCCAGCTAAACGTTTAACAATTGAAGAAgttatgaaaaataaatggattgcgCAATATACACAAGTCCCACAAACACCTTTGCATACAGGTAGAGTATTAAAAGAAGGTGAAGAAACATGGCCAGAAGTTCAAGAAGAAATGACAAGATCATTAGCAACAATGAGAGTTGATTACGATCAAGTAAGTAAAATGCATATTAAAGCATTAGATAATTCAAATAATGcattattaaataaaagacgaaaaaaaattgaagagAAACAAGGTAGTCCAAAAAAGTCGTGA
Protein Sequence: MRSVGFYDLNWYFNLTNSSSYSELQFLASRRAAAVAAAATVLPPPPPPPPPPPPPPSAGNQPPGVPPPPPQPHDFHPAYRIPGYMEHLYSLQHASPSASLHGFGINSDYLGARGGPLSDMHPPSSLASTDFHFSIDGSRLNSPRPGSIRASVSRKRALSSSPFSDSFDINSMIRFSPNSLATIVNGSRNSSTSGSYGHLSAGTMSPALGMHTGMAPHLQQLQAHLLRAGAGLLHPLPPHHTPPTASMFSLGHHPLQSASSMSKPSHMDDPSKKPEMPSSSSVVAQVEADSASNAMARRGRCKRDSISTTTHNEGENPTVDTTDIKDEPGDFIETNCHWRDCGIEFTTQEELVKHINNDHIQANKKSFVCRWEDCSREEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCCKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYVCKAPGCTKRYTDPSSLRKHVKTVHGVEFYANKKHKGSSHDTGNDEGGNQHHTGFDSSPRSEDMHSGKTASLSSPSIKSESEANSPSQPPVNSPMGVSHLINGGHEDFDCSPNVVATPLGTNVSAIDDPSWPYEDEDLEVADLPVVLRAMVGIGGPPGTGNGGGQSATISNPRNRFRSRLQAKSINALSNIPEINRCNLGIGELNQRITELKMEPGIPMPPKTIQPQNPNTQLTDLQLRLQPPNTNGQNQMIRRDSNNSNASTYYCSMRSADVSRRSSQTSQLSSISTMRPSGYNSSSFYDPISPGCSRRSSQMSMTTTGGQSLPPPPSSHLISSHLQRLQGTNNSGRHSIPNIPTQPFNTTNLHRNDRRQSEPVNQSYDRMLLSPLPLQPLSPSKSAKPAGANALVSRNTARDHHPNEEVVLDEVEEGEMVENKLVIPDEMLQYLNQIRERITKQIRNISQRTMFNQNATGGGGGGGGGIVASGDNNQQNQRNPKETPIINDYEISSTVLGLGINGKVVQCTNKKTGVKYALKVLLDNPKARREVDLHWRASGCRYIVNIIDVYENTYSGNKCLLVIMECMEGGELFQRIQDRQDGAFTEREAAQIMHEICVAVHYLHSMNIAHRDLKPENLLYTTPDANAILKLTDFGFAKETFIKDTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVIMYILLCGFPPFYSNHGLAISPGMKKRIRTGQYDFPDPEWKNVSKSAKDLIKGMLNVDPAKRLTIEEVMKNKWIAQYTQVPQTPLHTGRVLKEGEETWPEVQEEMTRSLATMRVDYDQVSKMHIKALDNSNNALLNKRRKKIEEKQGSPKKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -