Aant012580.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anthrax anthrax
Gene Symbol
nrf-6
Assembly
GCA_963971155.1
Location
OZ020117.1:64343184-64366855[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00013 0.0064 17.7 1.3 3 23 302 322 299 322 0.88
2 12 5.8e-07 2.8e-05 25.1 2.3 1 23 328 350 328 350 0.99
3 12 2.8e-05 0.0014 19.8 0.6 1 23 356 378 356 378 0.98
4 12 0.00099 0.048 15.0 0.8 1 19 384 402 384 407 0.91
5 12 0.00027 0.013 16.8 0.4 1 23 415 437 415 437 0.98
6 12 3e-06 0.00015 22.9 0.9 2 23 446 467 445 467 0.94
7 12 0.0013 0.064 14.6 3.2 1 23 491 514 491 514 0.98
8 12 0.24 12 7.4 1.9 1 23 536 558 536 558 0.98
9 12 0.0016 0.076 14.3 2.6 1 23 566 588 566 588 0.98
10 12 0.0088 0.43 12.0 0.8 1 23 593 616 593 616 0.96
11 12 0.0016 0.079 14.3 0.1 2 23 625 647 624 647 0.97
12 12 0.00023 0.011 17.0 0.3 3 23 654 674 652 674 0.95

Sequence Information

Coding Sequence
atgtttttaaaatttaattcagATATTTGTCGTGTTTGTTTAGAACAAGAGggaaaaatttcattatttgatAAAGAATCAACAGCTCAACAATTTCGTTTTTGTACATTACTAgagACATTTGAAAATGATGAATTACCGTCATCATTATGCATGAAAtgttttaaatgtttaaaaattgcaaatgattttaaaattaaagcAATATCGTCAGATAATTACTTAcgtaaatttttaaatacattaaataacaaatttagTAGTGCAAtagcaaataataaaaattcattagatgttgatataaatgaattaaatacaTTGCTAAcatttgatgatgatgatgataacgATTATGATGATAATGTTTGTGACGATCAAAGAAACAATCAACAGATGAAAAATGCAAGttcaaaaaatgaaagtaTGCTACATACCATTATAGAAAACGATAACAATATTGACGATGATGGTATGAATGATGATACATTAGATAAACCTTCATATAATATCgaaataattaaaatagaTGCTTCATCATCAGCAGTTATTTGTActgaagaaaagaaaattgacGATATTCAGAATACATCATCTGATATTGGGAATGTTGATAATAACGATTGTATTACGATTATTGAAGAGAATATAATTAATCATCATGAAGAAGAAACTGAAATATCGTTCacacaacaacaacaacaacaacaacaacagcaacaacaagATGATAATCCGGAAGATAATCATGATGCAAATGATGCAAGTAAAAGTGAATTTGTAATAACAACGATTGAACAAATTAAAGATGACGATCAACAACAACCGCAAAAGCAACGAAGAAtgataaaaaggaaaaaatataaaaatattaatcCAATTTTATCCGATAAAGATTCATGTGTATGCATTGAATGTAATAAAACGTTTGCATCAAAACCGAATTTAATGCGTCACTTATTAACGCACACAAATGCAAAACCATATCAATGTACTGTGTGTGGTGAATGTTTTACACAGAATGGTTCATTAAAAACACATATGTTACGACATACTGGTGAACGTCCGTACGTATGTGatatatgtaataaaacaTTTACAAGAAAACGAATACTAATGATACATTTAAGAATTCATACTGGTGATAAACCATATGAATGTGAGCaatgtaatgaaaaatttcgAGTTAAAGAATCATTGAGGagACATAATGTATTAAGACATTCAAAAGGTAAATTAAAAGAATATCCGTGCTCAGTATGTGACCGTATATTAAGTACAAAATACTCACTGaatatgcatttaaaattACATCAGAGTGATAAACAGCCAACAGTACAATGTCATATATGTGGTAAATCATTTGCaaataaatattcattaaaaaatcaCGTAGATGGACATACAGTAACAGAATCATCTACTGATCTACAATCATCACCGTCGTCACCGTCAACATCATCTTTAAGAAAATATCAATGTAAAGAATGTAAAAGagaatataaaacaaataatgcatatttaaagcatttacaaaaatttcataatacAACAACAGATACAAATAATGATGATACAGAAATCACAcaggaaaaacaaaacataaaatatcaATGTGATTTATGCAAAcagatatttttaaaaaaattccGTTTAATGCAGCATTTATTAACACATGaagatgaaaataatttaaattatagctgcagaaaatgtgaaaaaaatttcacaattagagaaaatCTTATCGaacatttacatacacatgatGATTTTCTATATAAATGTGATGAATGTAATGTTGGTTTTAATATAAAACGTGATCTTAAATTACATCGTTTAAATTATCACAAAGAGATTGTAAATGATTTAAACCAATGTGATGAATGCGGTGTTAAATTTGTAACTGGTGTTGATTTAAATGTtcatatattaacaaaacatGACACAATTGATATTAATTGTGATGAATGTGGcaaaaattttacatcaaATCGATTATATAAAGATCATATAATTGAACATAATATTATtgaattaacaaaaaatacaGAGCAAAAATGTACAGAAAAAGGAAACAATAGTTCAATATGGTTGGATCTTAATACAACATTATGGGGCATTAGGCAAGGATTACCATGGGCAattcaaaTGTACGATTCATCAGTGAAAATACCATTTGGTATTGAAGGTGGTTCTGTATATCAATTTGGTAATTTTGATGAATGTCTTAAcataaattatgaaaattatgataaaaattcaaaaaattataatcatCATTATAATCGACGAATAATGCCAAAATATTGTTTAGCTGATGTTATCGTAAATGGTTTACAAGTTAGATCTATAGCATCAAGGACATATGAGCCCAAAAATCATTCATTAGTTCATTGGGGCATATGTATACCAATATCATGCGGTACTCAAGATGTTGAAGATGTTATGTCGAATATCCTTGGTTACGAAGTGAATGTTGATGAAAACAAATGTACAATTCAAAAGGATTTTGAAGTTACCAAAGGAATGACAATATATGGttgTGTTGTACTATGTTTTGTTATGATGACATTATTTTGCACAtcatatcatttttatatgatttataaaagtgatataataaaacataattcgaataataattttataatggttgttaaatcattttcaattgTTGaaaatatgaaaaaattattccAACAAAGTAATGATACATTAGGTTTGAATGCAATTAATGGAGTTAAAGCGGTATCAATGATTTTCATTGTATTAGGAcattcattattatttgttattgGTGGTCCAGTATTAAATTCAGATTTTTTTGCAACAGACATTAAACGTGTTCAAAATGCATTCCTTATTAATTCACCTTTATTTGTTGACACTTTTTTATTACTTAGCGGTTTCCTATTTTGtagaattttaataaaagaattagAACGAAGAcatggaaaaataaattttgctattttatatgtatttcGTTATATTCGTTTAACACCAGCATATTTAGCTGTAATCGCATTTTATATGACATGGTTTCAAAATATTGGTAATGGACCATTATGGAATTCTCGAATTGGTATAGAACGTGAACGTTGTGAAAATTCATGGTGGataaatttactttatattaataattattttggAACTGAAAATTTGTGCATGTTCCAATCATGGTATCTATCAGTTGATACTCAACTTTTTATATTGGCTCCTATtattatttatcttttatgGAGATCTCGTAAATGGGGTGTCACTTTATTAGGAATATCAACATTTGTCACAACATTAATACcaatttgtttaacatattTTCAAGATTTAGATCCAACATTATTCGTATACGCAGATGAAGTAACTGATATTTCAACAAATCcatattttacaaaaatttatatgaaaactCATATGAGAGCAATTGCATACGTTTGCGGTCTAATTGTCGGCTTTATATTGCATGTAATTCAAGAAAAAAGcattaaattttcaaaatcgTTTGTAATGATAATGTGGACATTTTCATCGATAATTGGCATTATATCAATGTTTTCTGTAATGATATTCATAAATATGAGTTATACTACATTAGAAGGTGCTTTATATGCTGGCTTCCATAGACTTGGTTGGAGTATATTAACTGGTTGGATTATAATTGCATGTACAACTGGACATGGTGGTATATTGAAATCAATTTTGGCATCAAGAGTTTTTGCACCAATTAGCCGATTAACGTATTGTGCATATTTAACAAATGGTATTGTTGAACTTTATGAATTGGGTACATTGCGTGAACCAGTATATATGAGTCATGTTAATTTGaCTGGCCTTGCATTTACCCATACAATCTTCACATTTGCATTTGCATTGGTGCTATGTCTATTATTTGAATCACCAATTCATGGTATTGAGAAAATCTTGTTACGCAAAGATAATCAACGAAGGCAAATGGAAGAACGAAAATCAAAAGATACACCAAGTACATCAGAAGAAACAGCCTag
Protein Sequence
MFLKFNSDICRVCLEQEGKISLFDKESTAQQFRFCTLLETFENDELPSSLCMKCFKCLKIANDFKIKAISSDNYLRKFLNTLNNKFSSAIANNKNSLDVDINELNTLLTFDDDDDNDYDDNVCDDQRNNQQMKNASSKNESMLHTIIENDNNIDDDGMNDDTLDKPSYNIEIIKIDASSSAVICTEEKKIDDIQNTSSDIGNVDNNDCITIIEENIINHHEEETEISFTQQQQQQQQQQQQDDNPEDNHDANDASKSEFVITTIEQIKDDDQQQPQKQRRMIKRKKYKNINPILSDKDSCVCIECNKTFASKPNLMRHLLTHTNAKPYQCTVCGECFTQNGSLKTHMLRHTGERPYVCDICNKTFTRKRILMIHLRIHTGDKPYECEQCNEKFRVKESLRRHNVLRHSKGKLKEYPCSVCDRILSTKYSLNMHLKLHQSDKQPTVQCHICGKSFANKYSLKNHVDGHTVTESSTDLQSSPSSPSTSSLRKYQCKECKREYKTNNAYLKHLQKFHNTTTDTNNDDTEITQEKQNIKYQCDLCKQIFLKKFRLMQHLLTHEDENNLNYSCRKCEKNFTIRENLIEHLHTHDDFLYKCDECNVGFNIKRDLKLHRLNYHKEIVNDLNQCDECGVKFVTGVDLNVHILTKHDTIDINCDECGKNFTSNRLYKDHIIEHNIIELTKNTEQKCTEKGNNSSIWLDLNTTLWGIRQGLPWAIQMYDSSVKIPFGIEGGSVYQFGNFDECLNINYENYDKNSKNYNHHYNRRIMPKYCLADVIVNGLQVRSIASRTYEPKNHSLVHWGICIPISCGTQDVEDVMSNILGYEVNVDENKCTIQKDFEVTKGMTIYGCVVLCFVMMTLFCTSYHFYMIYKSDIIKHNSNNNFIMVVKSFSIVENMKKLFQQSNDTLGLNAINGVKAVSMIFIVLGHSLLFVIGGPVLNSDFFATDIKRVQNAFLINSPLFVDTFLLLSGFLFCRILIKELERRHGKINFAILYVFRYIRLTPAYLAVIAFYMTWFQNIGNGPLWNSRIGIERERCENSWWINLLYINNYFGTENLCMFQSWYLSVDTQLFILAPIIIYLLWRSRKWGVTLLGISTFVTTLIPICLTYFQDLDPTLFVYADEVTDISTNPYFTKIYMKTHMRAIAYVCGLIVGFILHVIQEKSIKFSKSFVMIMWTFSSIIGIISMFSVMIFINMSYTTLEGALYAGFHRLGWSILTGWIIIACTTGHGGILKSILASRVFAPISRLTYCAYLTNGIVELYELGTLREPVYMSHVNLTGLAFTHTIFTFAFALVLCLLFESPIHGIEKILLRKDNQRRQMEERKSKDTPSTSEETA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-