Aant003603.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anthrax anthrax
Gene Symbol
su(Hw)
Assembly
GCA_963971155.1
Location
OZ020117.1:5865097-5868150[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.067 3.2 9.2 1.5 1 19 110 128 110 131 0.92
2 12 2.6e-05 0.0012 20.0 1.7 2 23 181 203 180 203 0.94
3 12 0.00015 0.0071 17.6 3.1 1 20 237 256 237 258 0.93
4 12 2.6e-05 0.0012 20.0 0.9 3 23 273 293 272 293 0.98
5 12 1.8e-06 8.5e-05 23.6 0.1 1 23 303 325 303 325 0.99
6 12 1.7e-05 0.00084 20.5 1.3 1 23 331 353 331 353 0.99
7 12 4.6e-05 0.0022 19.2 1.8 1 23 359 381 359 381 0.99
8 12 1.7e-05 0.00083 20.5 0.4 3 23 389 409 388 409 0.99
9 12 0.23 11 7.5 0.4 1 23 419 442 419 442 0.94
10 12 0.003 0.15 13.4 1.2 2 23 453 475 452 475 0.95
11 12 0.0037 0.18 13.2 0.2 1 23 489 512 489 512 0.93
12 12 0.00015 0.0071 17.6 1.4 2 23 567 589 566 589 0.94

Sequence Information

Coding Sequence
ATGTCTAAACGAGAAGTTAAACTTTTAAATTCTACATTCGAAAAAAAGAATCCAAAACaattaagaaaagaaaaaattaaaatacaacCACCAGAAGAAAGTGCTGATGATGCTGATGATATAATTGAACattatgttttaattaataaagatgaagaatttaaatttgttaaaaagaaaaatgatttaataaataatactGTTAGTAATGATGAAGAGGAAGATGATGAAACAGAAGgtgatgataatgatgaaacaaaaattgaatCGAATGCATCTGAATTTCATGTTGAAGATGATACAAAAAGTGTACAAGAAGTATTAGAACATGTTTGTGGAAAATGTTATAAATCGTTTCCATCATATCAGCATTACGCAGCACATAGCATGTATTGCAAAAATGATGGTGAAATTGCTagaaatattgaaaatatgttGAAAAACTTACAAACCATTGAAGAGGAATCAACTGAATTAGATAAACAGGATATATGCATTTGTTGCAAAGAAAATTGGGAAACTGCACATaGTGGTCATATTCGTTGTCCAAAATGTCcaaaatcatttaaaaataatccAAGTTTTGAACGACATTTATGTTTAATACATTCAGATAATTTAGATTATGAATGTATGACATGCAATGCCAGATGTCCATCAGCTTGTATACTTGAATTACATCAGAAGGCACATTTACGTGGTAAACCGTTTGCATGTAGAAAATGTGGTGAAGAATTTACACgtaaatatcatttaaatcGTCATCATTTATATAGTAATTGTGAAATAAGTAATGTAACAAAAAAAGTTGCATTATGTAAAGTATGCGGAAAAGAATTTTATCGTTTAGATAATTTACGAATGCATTTAAAACAACATTTAGGACAAGATACAAAAACTAAAGATTATCCATGTCCGTATTGTGGTAAAGCATTTTACGGAACAGCAACATTAAATATTCATATAAGAACTCATACTGGTGAACGTCCATTTACTTGTGATTTATGTGGTAATTCTTTCCCATCTAATCCAGCCTTAAGAAAACATCATCGAACACATACTGGAGAGAGACCATACCAATGCACAAAgTGTTTTCGTTCATTTGCTGCAAAAGAAGTTCTCAATAGGCATATGAAAACGCATACTGGTGAAAAACCACACGGATGTGATCTATGCGGTAAAAGATTCATTCAAGCGACACAACTTAAACAACATTTGttaacacataaaaaaaaagaagcgGGTGGCAAAACGTTTTCATGTCGgaaatgtaaattattattagaaaCAAAAGAAGCacTTACCGAACATATGATAGAAAAACacgaaaatgaaaaaaaagagaaatgCGATATAGAGTGTCAGCATTGTGgtaaaattttacatacagAAGGTGGTCTGAAAAGACATATCACACGAGTTCATGTACAAAAAGCTATATTAGAAGACAATGGTGATTCACAATTCTTATGTGAAATATGtgatgaaatttttgaaaataagaaaaatcttgaatttcatattttaaaagtaCATGATAATAACGAAGAAAAGgaagaaattgaaattagtgatattttaattgaagAGGACAATACTAAGGATAATGCATATGAGGAAATAATATTTCAACAAGATATTGATATGGATTCAATGGAATTAGAACAAAAGCAAgataatcaaaaaaattctaaatggaattgtaaattttgtaataaaaaattcaataataataaaaaattaatagcaCATATGGAAAATGACCATGGGGCTGTTGTTTTATCAGTTGGTGAACAAAATAGCACACAAAATAATGATGAGATAACAgataatgaaattgaattttcagTTAAAGAAGAAGTTCACGATGAAGAGGATAATATTGAAATGGTTGAAATTGATGAAGATATGGATGGGGAAAATCGAATTGTAAAAACGATCACTGATGATAGCgacataaatataaatgacaaggaagaaaaaaataaaataattattgatAGTAAAAACAAGAGAAAGAGAAGTAAAGAAAATGATGCAGGTGATAAtagtgatgatgatgatgatgacgattatgttgtaataaaattgaaaaaatctaaaaataaaaaatcattatcaCCTGTTTTATCAATGGACGAAAAATCTTTAACAGAAAATGTTAAGAAACTTTTAGATTTATTAATTGACAAggatattttgaaaaaatttggTTATCCTAAAAAACCAGTTGAGGAAGTTTTAATTAAAGTTATAAGAAATTGTGgacataaaattaaaaataatgtttcATCAAATGATTACATGACTCGTTTAAGAgattatgtaaaattattatttaccGTTGTTGTAGATAATGATTCAATTAGGGAATTGTTAAATAATCATCCTGTAGATAAAGTTATTTATCAAGTTTTAGAAATGGCGGGAcgaaacaattaa
Protein Sequence
MSKREVKLLNSTFEKKNPKQLRKEKIKIQPPEESADDADDIIEHYVLINKDEEFKFVKKKNDLINNTVSNDEEEDDETEGDDNDETKIESNASEFHVEDDTKSVQEVLEHVCGKCYKSFPSYQHYAAHSMYCKNDGEIARNIENMLKNLQTIEEESTELDKQDICICCKENWETAHSGHIRCPKCPKSFKNNPSFERHLCLIHSDNLDYECMTCNARCPSACILELHQKAHLRGKPFACRKCGEEFTRKYHLNRHHLYSNCEISNVTKKVALCKVCGKEFYRLDNLRMHLKQHLGQDTKTKDYPCPYCGKAFYGTATLNIHIRTHTGERPFTCDLCGNSFPSNPALRKHHRTHTGERPYQCTKCFRSFAAKEVLNRHMKTHTGEKPHGCDLCGKRFIQATQLKQHLLTHKKKEAGGKTFSCRKCKLLLETKEALTEHMIEKHENEKKEKCDIECQHCGKILHTEGGLKRHITRVHVQKAILEDNGDSQFLCEICDEIFENKKNLEFHILKVHDNNEEKEEIEISDILIEEDNTKDNAYEEIIFQQDIDMDSMELEQKQDNQKNSKWNCKFCNKKFNNNKKLIAHMENDHGAVVLSVGEQNSTQNNDEITDNEIEFSVKEEVHDEEDNIEMVEIDEDMDGENRIVKTITDDSDININDKEEKNKIIIDSKNKRKRSKENDAGDNSDDDDDDDYVVIKLKKSKNKKSLSPVLSMDEKSLTENVKKLLDLLIDKDILKKFGYPKKPVEEVLIKVIRNCGHKIKNNVSSNDYMTRLRDYVKLLFTVVVDNDSIRELLNNHPVDKVIYQVLEMAGRNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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