Basic Information

Gene Symbol
-
Assembly
GCA_951804975.1
Location
OX638112.1:33577278-33585891[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 4.7 2.4e+03 2.0 0.6 2 21 116 135 116 136 0.91
2 21 0.13 65 6.9 0.3 2 23 142 163 142 163 0.95
3 21 7 3.6e+03 1.4 4.8 1 23 177 200 177 200 0.90
4 21 0.22 1.1e+02 6.1 2.7 1 23 529 552 529 552 0.95
5 21 0.01 5.3 10.3 3.3 2 23 585 606 584 606 0.96
6 21 0.051 26 8.2 2.2 1 21 633 653 633 654 0.94
7 21 0.00022 0.11 15.6 1.1 1 22 767 788 767 788 0.96
8 21 0.00056 0.28 14.3 0.5 2 23 796 818 796 818 0.94
9 21 0.0014 0.71 13.1 3.1 1 23 828 851 828 851 0.96
10 21 1.5 7.7e+02 3.5 0.1 2 19 872 889 871 892 0.88
11 21 0.026 13 9.1 5.5 1 23 899 922 899 922 0.96
12 21 0.01 5.1 10.4 2.2 1 19 933 951 933 952 0.96
13 21 0.021 11 9.4 0.4 3 19 998 1014 996 1016 0.95
14 21 0.00053 0.27 14.4 3.3 1 23 1024 1047 1024 1047 0.94
15 21 0.016 8.2 9.7 0.2 1 19 1111 1129 1111 1132 0.94
16 21 0.003 1.5 12.0 3.7 1 23 1139 1161 1139 1161 0.97
17 21 0.015 7.8 9.8 0.4 1 23 1171 1194 1171 1194 0.86
18 21 0.00011 0.054 16.6 0.3 3 21 1252 1270 1250 1271 0.93
19 21 0.39 2e+02 5.4 1.4 1 23 1278 1300 1278 1300 0.87
20 21 0.19 94 6.4 1.9 1 23 1310 1333 1310 1333 0.89
21 21 0.061 31 7.9 0.3 6 23 1426 1444 1422 1444 0.94

Sequence Information

Coding Sequence
ATGGCTCGTGCTTTGATCTACAAGAGGTCCGTGGATGCAGTTTTGGTAGACATCCAGCTTGGTAAAGTAGATcaTGGGATAAGGATTAAAGAGGAGCCATTCGACGCAGAAATCCCTAATCATGACGATTCTCCATGGATGGGTAAGAACAGGGAAGGTCGGAGTAGGATAGCATCGTCTACAGTTCAATCTTCGGATGATGTTAATTGTAACGAAGGTAAACATGCGTCATTTCCGGTATCTACACGCTGGAAGAATAATAAACGCGGTCGTTGCGAGGAAAAATGTAAAGAATTGAATTCGTCTTTGAAAACGGCGGGAAAGGATTTGTCTGAAGATGTGAGAACGTGCCATGTTTGTTTTGTACAATTCGGCACGATACGTGGCTTAACAATGCATAAGCAAAAGGCTTCTGAACAGAACACTTGCGAAATTTGCTATAGGTTGTTTCGGTCAGATGAGCAATTGGCGTCTCATAAGGCTTACCATAAGAACAAGTGCGAAGTAGTTAATGCTTCGAATGTTCGTTACATTTGCCAGTTTTGCAATCGAGGGTTTTTCCATAAGAATCCTATTCAATCTCATTTGTTCCATCAACACAGAGACCTGATAGATTCCGGTCAAACGGAACTCAAGAGAATTACGGATAACACGACGATAAAGACTGATTCAGTGGACATTGATACGGAAATATCACCGAAACAGACTGCTTCGAGGAATTCAATCGCGAAGACACTGAAACGTCTAACGTCTGAGAGGAAAATGAACAGCAATCAGAAAGATTTACTCGCAAAAACGTTGAAGAGCACGCCTAAGAAGAAGAAGTCGTCGAAAAGATTGAACAATTCATGTGAGACACCCTCGAAAAGGATGAGACAGACCATTCTTACAGATTTCATGTCGCCTTATAATACCAGCCAAAGCAATAAATCATTGGATCATCAACCGGGAACGAGCGAGATGTTTGACGACGACGAGTCGAAACTTTTACAGAAGATCGAAATGTCTACTCCCGTTAAGTGCGCCGAAACTCCCATGTTCGATGATAAAAAGCCATTTGTTCGTATACACATGTATCCAAACCTTATGATGTCGCTTTTAGACGACAACGAAATGACATCACCTACAACCTCTTCTACTCCACGCAGTACGCTGTACAATTTTCGATCGGCAAGCAGAAATTCCTACAGTTCAAAGGAATCAAACTGTTCTAGGGAtacgaataaatcttccaaaagaaaaagatcCCCCAACACGCCTAAGCGATACAAAAGATCATTGTCGCTGGAGCAGAAGCTCAAGCTTTGGTGCAAAGAGTGCGTGATCTATCTGGAGAGATGCGACAAAGTTTCCAACGGCGCAAATACGAAATCTAACGGGTCGAAGGATGTTATATCTCGGCAAGTGAAAAAAGAGTTGGAGGATCCTGAGAAAACGAATGAAGAAAATAATGCGTCGTTGGAAAGCTCAGAAATTTCATCGATAAAATCTCTCGGGGAGGTGAAGCTTAAGAACGAATCAACGATACCTAAGCAACAGTCGGATTTGCTTGAGAGTGACGTGAAATCTAACCAGCTAAAATTGTTTCGGTGCAATCTGTGCAAAAAGCTGTTCCTCTCCCAAGAGAACATGCGCGAGCACAAGAAACTGTTCCACGTGATTTACATGTCGAGCATATGTAACGCGCGTTTCAAAGTTATGAACGCACTGTTGCGCCACTACTGGCAGCAGCATATCATTCTCAGGCAGAAGAAATGCTGTGTGTGCGACGAAAAGTTCAGCAGCACGATCCTGTTGAAGAAACACCTGACTTTGCATTGTGTGAAAACCGTGCAGTCGAAGAAAGACACTCTACCGATCGACGTAGAGCCAAGCTGCAACGTATTCAAGAGACGTTACCGGTGCGAAGGCTGCAAGAAGAGATTTCTGTTGAAATCCTGTTTGACGCAGCACGAGAGAGTGTGCAGTCGTATGAAAACCTTGACGAACGATAAACGGCAAGCTCGATCGTTGGTTTCGAAAGAGATAGACAATAGGAAAGCTAGTTCGGTAGATAAGAAGCAAGTTTCTAATCCGGAGATGTGTACGTCTAGCGAACAACAAGTAGATGGAGTTAGTTCGAGAACAACGCTACCTAAAATTGTCGAACAACCTGTAGAAGATCCAGTTAAAACTGTAACGTATCCGCCTATTTCCAATGATCCTCCATTGAAACCGGGTACTATGACCAGTAAAAGTCCGATTAATGGGATGGCGTACGCGCAGGGTTATCAAATAAACACGCTGGTCCAAGGGACCTTTCCCTGTTCCATTTGCGACAAACAGTTCCGCACGTTTCCGAATCTTTGCATACACGAGCGCACCTTCTGCAAACCACTGGTGAACCGTTGCAATACTTGCAGCACCGCGTTCCCCACTAAGAAATTGTTACAGATTCACATGCTCGCGACTCACACGTTGTTGAACAGGGATAAATACAAATTCGTTTGTAAATTTTGCAACCAAGGTTTCACGAAACGTATGAACCTTCAGATACACGAGCGACACCTACACATCGATCAGATCTCTCCTAAACCGTTGCAAAATTCCGACAGCCTTTTCAACGTGAACACAGTCTGCAACGTGTGCAATCTGATGTTCGAGTCCTATGAACGTTTCGTTCAGCACAATATGTATTACTACAAGGAACAAATGTTCACGTGCATGCTATGCCCCAAATCGTTCTGTGGTATGTACACGCTTCATCGCCACTATAAGCTGATGCATCGCGCGGAGAGTAGAGAACCGTCGTACAATTACACCTGCGACATTTGCAACGAGATGTTCAACTATGATTCGCATCTGCACTCGCACAAGTGGCACGTTCACCTGCACAACGATTCGTCGGAACAGGCTAGTTTAAACGCCATGCAAGATCACAGCTACGCTCTAACGCCTAACATGGATATTTCAGCCTCGGAATTGCAAGGGCTACCGGTTAGGATGTTCGGATGCAATATTTGCGACCTGCACTTCACCAATACGAAAGATCTATGGGTTCACAAGGTGGAGTACTCGATGAACGGTGATTTTCATTGCAAGATATGCAACCGAAGGTATTCAACCAGCAATATGCTTGCCAAGCATCAGAGTTTGAGTCACGTCGAATGTGACGCGAACAGCGTTTACACATGCTGCATGTGTCAGGAAGTGTTGACGACCAGCACGTCGATCCTCTGTCATGAGAGACATTTTCACTTAAACGACGCCAATAATAGCTTGCCGAAAGGAATAAACACGGTTTCGCGACAGTTAGACAAGGCTAGCTTACTTGATACTCTGAACGGAAGCTTCAATTGCTTGGTATGCGACACAAGATACAAAACACTGGGTGATCTGAAGGTACATTTTCTCGAGTACTCCAACATAGGCGCATTCAGCTGTACCGTGTGCAATAGGAAATTCTCCAACTGTTACGTACTCGAGGTGCACAAGCTGAAACACACCACGCTTAGTGCGACTATGTTTCGACACAGGTGTCCTATATGCAACGAGGGTTTCACGACCGCTGTGAACGTTCGACCGCACGTGTTACATGTGCATCGATACGAAAGCTTCGGTAGTCACAACGTTAAGGATTTCATGTTAGCCAAATCGCCTCACATCGTTGACAACCGTCAGAAGAATGTCACGCGCTCGGAACTCACAATATTGGCCAATAATAACGCGCTAGCTTCACCCAGTTCCGACAAGTCGACGCAATCCACGGTGAACTGTCCCGAATGCGACATATCGTTCAGCAGCGCGAAACATCTGGCTAAGCACAGGTCTCGGTTTTGCAACGAAGGGAATCACGAGTGCTCGAAATGTGGCCGTAAATTCCTTTGGATCACGTTGCTGCAGGCACATTTGAAGAAACACTCGTCTAAGTCGAACTTTTTCTTGAAGTACAAGTGTCCTCATTGCGACGACAAGTTCCGAAGCACCGTGGCCGTCTACTCGCATATCGTTCACCTCCACGGCAAGGACAAGTTAGCTACTCCGATTAAAAACATGAATAATTCGGACCACGATAACGTTATTGTATGCGATTCCACGGTTACCATGATCGAGGAGAACGTTGCTAAGGATGCTGATCAATCGAAGGAGGCGAATACCGTGGTGGAAACTACCGAGGAACAGAAGGATGAATCGACTGCGAAGAGATTGAAAGCGCACTTTATGTTAACGCATTTTAATAAAACGTTAACAGAGTTCAGTTACGCAAATATCAAGGATGGTATGAGGTGTATCGCCTGCGGTTCAAGCTTCGTCGATCAACAGGAATTGGATaagcatatgcagaacaagcataTAACCTATTTTTCCTTGTCGAGTATTGAGACTGATAAGTCTGAACAGACTAACGAGATTGAACAGGCTAGCAGTTCTGAACTAATTGAAGAGCCTGTACAGGCTAGCAGTTCTGAACAGATTAAAGAGTCTGAACACGTCAGCAGTTCTGAACAAATTGACAAACCTGAACAGGCTGGTAATCCTGAAGAGATTAACGAGCCTGAACAGGCTAGCGATTTTGAAAAGATTAACGAGACTGAACAGGTTGGTAATCCTGAAAAGATCAACGAGCTTGAACAGGCTGGCAATTTTGAAAAGATTAACGAGACTAAACAGGCTGATAATCCTGAAAAGATCAACGAGCCTGAGCAGGCTAGCAGTTCTGAACAGATTGAAGAGCCTGTACAGGCTAGCAGTTCTGAACAAATTGACAAACCTGAACAGGCTGGTAATTTTGAAGAGATTAACGAGCTTGAACAAGCTAGCAGTTCTGAAATCATTAACAACCCTGAACAGGCTGGTAATCCTGAAAAGATTAGCGAGCCTGAACAGGCTAGCAGTTTTGAAATCATTAACAAGCCTGAACAGGCTGGTAATCCTGAAAAGATTAGCGAACCTGAACAGGCTAGCAGTTTTGAAAAGATTAGCGAGCCTGAACAGGCTAGCAGTTCTGAAAAGATTAACGAGACTGAACAGGTTGGTAATCCTGAAAAGATTAACGAGCCTGAACAGGCTGGCAATCCTGGAAAGATTAACGAGCCTGAGCAAACTAGCAGTTCTGAACAGATTAATAACCCGAACAAGTCTGAATGCATAGAACTTGATTCTTCGCCCGAGAGACATGACGTTGATGTGATAGAAATGCTTTGGAAGAAGAATTCGAAGCCTGTCGAGTGTGTGACTGTCGACGAGAGTTCGAACGATTCCGATATCCAGATGATCGACGTGATCAAGCATCGACCTTCTGTAATCCGACCGATTGTTGGATTACACAGCCAGGTTGTTTCATCGGGGGGAATCCTTGAAAATTTAAGCAGTGACACAGTTAATGAGGAAAATCTTACATGGTTCACGAAGATGATGTGTTGA
Protein Sequence
MARALIYKRSVDAVLVDIQLGKVDHGIRIKEEPFDAEIPNHDDSPWMGKNREGRSRIASSTVQSSDDVNCNEGKHASFPVSTRWKNNKRGRCEEKCKELNSSLKTAGKDLSEDVRTCHVCFVQFGTIRGLTMHKQKASEQNTCEICYRLFRSDEQLASHKAYHKNKCEVVNASNVRYICQFCNRGFFHKNPIQSHLFHQHRDLIDSGQTELKRITDNTTIKTDSVDIDTEISPKQTASRNSIAKTLKRLTSERKMNSNQKDLLAKTLKSTPKKKKSSKRLNNSCETPSKRMRQTILTDFMSPYNTSQSNKSLDHQPGTSEMFDDDESKLLQKIEMSTPVKCAETPMFDDKKPFVRIHMYPNLMMSLLDDNEMTSPTTSSTPRSTLYNFRSASRNSYSSKESNCSRDTNKSSKRKRSPNTPKRYKRSLSLEQKLKLWCKECVIYLERCDKVSNGANTKSNGSKDVISRQVKKELEDPEKTNEENNASLESSEISSIKSLGEVKLKNESTIPKQQSDLLESDVKSNQLKLFRCNLCKKLFLSQENMREHKKLFHVIYMSSICNARFKVMNALLRHYWQQHIILRQKKCCVCDEKFSSTILLKKHLTLHCVKTVQSKKDTLPIDVEPSCNVFKRRYRCEGCKKRFLLKSCLTQHERVCSRMKTLTNDKRQARSLVSKEIDNRKASSVDKKQVSNPEMCTSSEQQVDGVSSRTTLPKIVEQPVEDPVKTVTYPPISNDPPLKPGTMTSKSPINGMAYAQGYQINTLVQGTFPCSICDKQFRTFPNLCIHERTFCKPLVNRCNTCSTAFPTKKLLQIHMLATHTLLNRDKYKFVCKFCNQGFTKRMNLQIHERHLHIDQISPKPLQNSDSLFNVNTVCNVCNLMFESYERFVQHNMYYYKEQMFTCMLCPKSFCGMYTLHRHYKLMHRAESREPSYNYTCDICNEMFNYDSHLHSHKWHVHLHNDSSEQASLNAMQDHSYALTPNMDISASELQGLPVRMFGCNICDLHFTNTKDLWVHKVEYSMNGDFHCKICNRRYSTSNMLAKHQSLSHVECDANSVYTCCMCQEVLTTSTSILCHERHFHLNDANNSLPKGINTVSRQLDKASLLDTLNGSFNCLVCDTRYKTLGDLKVHFLEYSNIGAFSCTVCNRKFSNCYVLEVHKLKHTTLSATMFRHRCPICNEGFTTAVNVRPHVLHVHRYESFGSHNVKDFMLAKSPHIVDNRQKNVTRSELTILANNNALASPSSDKSTQSTVNCPECDISFSSAKHLAKHRSRFCNEGNHECSKCGRKFLWITLLQAHLKKHSSKSNFFLKYKCPHCDDKFRSTVAVYSHIVHLHGKDKLATPIKNMNNSDHDNVIVCDSTVTMIEENVAKDADQSKEANTVVETTEEQKDESTAKRLKAHFMLTHFNKTLTEFSYANIKDGMRCIACGSSFVDQQELDKHMQNKHITYFSLSSIETDKSEQTNEIEQASSSELIEEPVQASSSEQIKESEHVSSSEQIDKPEQAGNPEEINEPEQASDFEKINETEQVGNPEKINELEQAGNFEKINETKQADNPEKINEPEQASSSEQIEEPVQASSSEQIDKPEQAGNFEEINELEQASSSEIINNPEQAGNPEKISEPEQASSFEIINKPEQAGNPEKISEPEQASSFEKISEPEQASSSEKINETEQVGNPEKINEPEQAGNPGKINEPEQTSSSEQINNPNKSECIELDSSPERHDVDVIEMLWKKNSKPVECVTVDESSNDSDIQMIDVIKHRPSVIRPIVGLHSQVVSSGGILENLSSDTVNEENLTWFTKMMC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-