Basic Information

Insect: Anthophora plumipes
Gene Symbol: topi
Assembly: GCA_951804975.1
Location: OX638111.1:29324846-29327334[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.3 6.3e+02 3.8 3.9 1 23 248 270 248 270 0.88

2 15 0.073 37 7.7 1.1 2 23 277 299 276 299 0.95

3 15 0.002 1 12.6 0.4 2 21 306 325 305 326 0.92

4 15 0.00029 0.14 15.3 2.4 1 23 333 355 333 355 0.97

5 15 2.7e-07 0.00013 24.8 1.4 1 23 361 383 361 383 0.98

6 15 0.25 1.3e+02 6.0 5.6 1 23 432 454 432 454 0.96

7 15 0.0075 3.8 10.8 1.3 1 23 460 482 460 482 0.94

8 15 0.014 7.3 9.9 0.7 1 23 492 515 492 515 0.94

9 15 2.4 1.2e+03 2.9 0.0 1 19 529 547 529 550 0.86

10 15 0.0051 2.6 11.3 0.1 1 23 555 577 555 577 0.98

11 15 2.3e-06 0.0011 21.9 3.1 1 23 583 605 583 605 0.98

12 15 0.00015 0.073 16.2 0.4 1 23 611 634 611 634 0.97

13 15 0.055 28 8.1 0.7 1 23 640 662 640 662 0.89

14 15 3.6e-07 0.00018 24.4 2.2 1 23 668 690 668 690 0.99

15 15 6.9e-06 0.0035 20.3 4.9 1 23 696 719 696 719 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.3	6.3e+02	3.8	3.9	1	23	248	270	248	270	0.88
2	15	0.073	37	7.7	1.1	2	23	277	299	276	299	0.95
3	15	0.002	1	12.6	0.4	2	21	306	325	305	326	0.92
4	15	0.00029	0.14	15.3	2.4	1	23	333	355	333	355	0.97
5	15	2.7e-07	0.00013	24.8	1.4	1	23	361	383	361	383	0.98
6	15	0.25	1.3e+02	6.0	5.6	1	23	432	454	432	454	0.96
7	15	0.0075	3.8	10.8	1.3	1	23	460	482	460	482	0.94
8	15	0.014	7.3	9.9	0.7	1	23	492	515	492	515	0.94
9	15	2.4	1.2e+03	2.9	0.0	1	19	529	547	529	550	0.86
10	15	0.0051	2.6	11.3	0.1	1	23	555	577	555	577	0.98
11	15	2.3e-06	0.0011	21.9	3.1	1	23	583	605	583	605	0.98
12	15	0.00015	0.073	16.2	0.4	1	23	611	634	611	634	0.97
13	15	0.055	28	8.1	0.7	1	23	640	662	640	662	0.89
14	15	3.6e-07	0.00018	24.4	2.2	1	23	668	690	668	690	0.99
15	15	6.9e-06	0.0035	20.3	4.9	1	23	696	719	696	719	0.96

Sequence Information

Coding Sequence: ATGAATACCGGAAAAACGGAATCGATTAGCACATTGAGCGAGCACgaagataatcttgatgattttgaGGGATCGATTATTTGGTCCCAAGAAGAACCGCTTTCTTCAAATGAGATTTTAGAATTCACACCGGATATGGAAAATCAAAATCGATTAAAATCTTTATGCCGTTTATGCGCTGGAGAAACTCTAaatcctatttatatttactccGAATTCGGCGAGTCTCTGAGacttttacataaaataaatacatgtTTAAGTATTAAGGTAAAAAAAACTGATCACCTCCCTAAGCAACTTTGCCCAACATGTGTTGAAAAGATTACATGGTGTAATGAATTTGATGTTCAGTGCATAAAAGCTGAGGAAACTCTTCTTGAGATATTAAAGCAGAAACATTCTTTCACTAATGCTATAAATGATGTAAATTTTCAAGAGAATACAAACTCTTGTCCATTATGTATTGAAGGACGAATGAGAATTTATGAGGAAGATAAGGAAATTGGAACAGACATTCAATTGTACGACAGTGATATTGTTCTTGAAAGTAGCGACGAAGAACAAATCCCAAACGAAATTAAGATTGATAACGAGCCTGAAAGTGAAGCTATAACATTGTACTGTTTAGGTACTATGCAAAAGTATTTGAAATGTGGAGCGTGCATGAACTTGTATCACACAAAAGAAACTCTGGATGAACATAAATGTAAACCTAACATACAGTGCACCTCTAAGCCATATAAGTGTGATATATGCTTTGCAACTTTTACATTTGAAGAACGATTGCAGTTCCATCAACATTTTCACAAAGATGTGAAAGCGTTGTAttgtgaaatatgcaaaattacgTTTGGGAAAGAACTGAAATTGTTTTACCATTACAAAAGataCCACTGTAAAGATGGTAGGGTATCATGTTTACAATGtggaaaattgtttgaaaatcaGGAAGGTTTGAAAAAGCATGTTTGTGTGGATGGGAAAACGAGACCTCATGTATGTGAGATCTGTTCCAAGGGATTCTGTGATGGATACACTTTAAAACGTCATGTGGTAACTCATCTTCCGGAAAAGCCATATAAATGTCCTGAATGTTCAAAAAGTTTTACACAGAAATCCAGATTGAATAAGCATGTGGCTTCGCATAgtgttatttttgaaaacagTCAAACAATTTGGAGATGTGTTCGCTGTGGTGAAGCATTTGGAAGTTGTGAATCTGCAGATGAACACTGCAAAAAACACGAGGAGAAAATTAGTCTTATTGAAGAGCTACAAGTATTGAAACTGTATCATTGTGAATTCTGCAGTAGTCACTTCGTCGACATAGATCATCTAAAAAGTCATAGAGAATTACACGCTGTTGAAAAACCATACTCTTGCAATCATTGCAACACTATGTTCAAATCTTTTGCAGAAGCTGTTCTTCATTGGAAAGAACATCCAAGAATATTCAAAGTATTGGTAGTGTTCTTATGTGAAATATGTGACAGAGATGTTAAAGAACTGTCTCTGCTTTATAAACATAAACAGAAAAGGCATCAACCGATGCCTAGAAAATCGGAGAAAGGTAAAGAGAAGTTCATTTGCGAACTCTGTGGAAGTATCTTTGCAGCTATAGAAGATTTTCAAGAACATGGAAAATATAGATGCTCAAAATTTCCATGCGACATTTGTGGCAGCCTTCTGCCAACAGCTAATTCATTGAATGCTCATAAAAGAAGACATAGCGGGCTACGACCATACGTTTGCAATATTTGTGGTAAAAGTTACACACAGTCTAGTCATATGTGGACTCACAAAAGGTTTCATATGGGTGTGAAACCATACGCTTGTGAATATTGCGATCAGAGATTCACAATAAAACCAGATTTAGCAGATCATACTAGGAAGAAGCATACACGGGAACGACCCTTTAAATGTGATGTTTGTAATAAGGCCTTTTTAACAGGGTCTGTCTTCTATCAACACAGACTAATACACAGAGGAGACCGTAGATACAAATGTCACTATTGCGAAAAAGCATTCACAAGAACAGAAGCTCTGAATAATCATATAAAAATACACACTGGAGAAAAACCACATGCTTGTGATGTTTGTGGAAGATGTTTCAGGCAGAAGGGAGATATGAGAAAGCACAGACGAACTCAGCATACTGCTAAACAAGAGTCAAAATAA
Protein Sequence: MNTGKTESISTLSEHEDNLDDFEGSIIWSQEEPLSSNEILEFTPDMENQNRLKSLCRLCAGETLNPIYIYSEFGESLRLLHKINTCLSIKVKKTDHLPKQLCPTCVEKITWCNEFDVQCIKAEETLLEILKQKHSFTNAINDVNFQENTNSCPLCIEGRMRIYEEDKEIGTDIQLYDSDIVLESSDEEQIPNEIKIDNEPESEAITLYCLGTMQKYLKCGACMNLYHTKETLDEHKCKPNIQCTSKPYKCDICFATFTFEERLQFHQHFHKDVKALYCEICKITFGKELKLFYHYKRYHCKDGRVSCLQCGKLFENQEGLKKHVCVDGKTRPHVCEICSKGFCDGYTLKRHVVTHLPEKPYKCPECSKSFTQKSRLNKHVASHSVIFENSQTIWRCVRCGEAFGSCESADEHCKKHEEKISLIEELQVLKLYHCEFCSSHFVDIDHLKSHRELHAVEKPYSCNHCNTMFKSFAEAVLHWKEHPRIFKVLVVFLCEICDRDVKELSLLYKHKQKRHQPMPRKSEKGKEKFICELCGSIFAAIEDFQEHGKYRCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHTAKQESK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00085636;
90% Identity: iTF_01417868;
80% Identity: -