Basic Information

Gene Symbol
zfpm1
Assembly
None
Location
GWHABGR00000004:905014-924936[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 5.1 3.3e+02 2.3 0.2 2 23 6 27 5 27 0.94
2 13 0.0071 0.46 11.2 0.8 1 23 1008 1031 1008 1031 0.95
3 13 1.5e-05 0.001 19.6 1.7 2 23 1135 1156 1134 1156 0.97
4 13 0.00012 0.0079 16.8 1.8 1 23 1162 1184 1162 1184 0.98
5 13 0.015 0.95 10.3 2.8 2 23 1191 1212 1190 1213 0.95
6 13 0.6 39 5.2 1.0 5 23 1226 1244 1225 1244 0.96
7 13 0.00027 0.018 15.7 1.8 2 23 1250 1272 1249 1272 0.96
8 13 0.0064 0.41 11.4 0.2 2 23 1289 1309 1288 1309 0.97
9 13 6.7e-05 0.0044 17.6 0.5 1 20 1315 1334 1315 1337 0.92
10 13 0.017 1.1 10.1 3.1 1 23 1345 1367 1345 1367 0.98
11 13 0.0052 0.34 11.7 7.2 1 23 1373 1395 1373 1395 0.98
12 13 6.1e-06 0.0004 20.9 1.3 1 23 1401 1425 1401 1425 0.98
13 13 0.001 0.066 13.9 4.2 1 23 1431 1453 1431 1454 0.95

Sequence Information

Coding Sequence
ATGGATCAGCTCGTTCAGTGTCCTGTTTGCACACTCTATCTCCATAATGGGATAACGTTGGAATCCCATTTAGACACACATCCCAAAGATCAAGTTATAAAAGCTCTTTGTAGCCTTGCAACATCAAAAGGTAATTATACAAGCAGAACATCTTCACCATTGCATTCAGAACGTTCATATAGAAGTCGGTCTCGCACACCTGCAACAGAGGACAAATGGAACGGATCTCATAGACCAGGTGAACATGAACGGTATTGGAGAAGAACTCCAAGTAGAACCCCTAAATCCACCACATCAACAAGCATTTCAAGAAATGGTACTCCAGATATGAAAATAACTGATGGCCTTGCTTTTGAAAGTGCAGCAAGTGGGCATAATTCCCTCTCATCATATGCATTGAAACAGGATAAACTACAACAAACATTTCAAAACAGTTCTATGTCAGATTTTGAACAAACAGGCGGGTATTACCAAGATACACAGGATGATAGAGAAATAAAATATTCCCGTAGTACAGAATACAATACAATGGATAATGCTAATGGTGTTTTTACATATAATGTACAATCCCCAGGATCTGGATTGAGGTATCCTACTCACAGCAGTTTAATTTCAAACATACCAGGAAGGAAGGGTTCTGGTTTCATCAAAATTGTACAGAAACCAAATAACATATTTGTTAAAACTGATACAGGTGGTATGCAGTATTTACAGGGTGCTAAACCTATGCATGTTATGGTTCCTGGCACACAAACATATGTCCAAAAGAATATGCAGAATAACATGATGATTCCAGGTAGTATTTCACAATCACAAGTCCAAATAGACCCCAAGGGTGTACCACAACAATTAACTGGAAATCAATTTAATCAATTCACAACTGGTAGTTACACTCCTGGTTTGTCTACAGTGGTAACTCAGAATTCACAAATAATCTACAGAGAGATGTTGCATAATATTGATGGTAAACAATTTATCTCAAGTGTGCCTGCAGTTATTCCTACAGGGCCTGATAATCTTCCAAATACACCTCAGACTGCATCTATGTATCAAAATTTAATGGTTGTAGATCAATTTGGTTCTTGTATGTACACAAATCCTCAACAAGTATTGCCTAAACCTGGTACTCCAACAATGTATGCAGATTCTGGAACTTTGGTGCCAAGTATGCATATGTCAAAAACTCCTGTACCTGCAATTAATGATCCTAAAACATTGATTATTGAAGTAAGTCCAATAGTTAATCCAGAACAAGCAGCTTCTTGCAGTGTTTTGAATGATCATGTTCCAGACACCACCACAAGGGCTGATAAATTAAATGAGCCAGAAATGGAGAAAGTGGAAAATAAGTGTGAGGCATCTGTTTCAACCAAAGGTTTAAAAATTCTAAGTAATATTAAAGTAGAAGTACCAGTACAGCATAATAAGAATATGATTAATACAATTATGGACTTGACGGGCCCCAGTGATCCTGAATATTCAAAGAAAGAAGATTATTCTGAATCGCCTGAAAAAGTCCTATCCAAGTTAGAAGAAAAGAAAGAGAACATAATAGATGATAACACACAACCTTCCAATTCGAGTATTGATAGTGTAGTATCTCATGCATTTTCTGTGATAAAAAATGTTGGCAATCCTTCATCACAAAAGGATTCATCCAGTAAATCTTTAGATAGCAAATTAGATACAGATTATGGTGATAGCTGCCCTGTGCCAGACTTAATATGTAATGAAAAAGCATCAATATCACCTTGTAGTGAGTTATCAGAAAGTGGGGAAAATTCCACAGATCGTACCTCGATATCTTCAAAAGTCGAGACAGATAATAGCCAATTTTGTGAGAGTATAGAGAGTGTTGAAAAGAAAGTTCAATTACCCAATAAGCCAAATAGATTAAATTTATTAAGACTGAACAATATATATGTGAAGAAAAATAAAAAAGTTTTAAAAATAAAAAATTCAAAGCAAAATTCTGATAAAAGTTTGAGTATTATTGATACAGAGCCAGTACCTTCATCATCATCTGAGAAGTCTCCAGAAAATTTTGCTATAAATAAGGTCCACAGAGTAGAAATGTCTGTAGAAAGAGAATGTTCAACTCTGCATACAGTGTCTGTGGAGGAGATTAAGCAAAATGAAAACAATGATGAGAGCAATGAGAAGAATGACTTTGATGCTGACACAGAGGAGCAGGCCATGGATATAGAGCCAATCTCACCATCTCAATTACGTACAACTGAGTTTATAACACAAGTAGATATGGTGCAGGTAAAGGAAGAGATTAGCACTAGTAATGAAGGTGGTTTTAGCAATGAAACTGCTGCATCTGAACGTATTTTAACCCCACTAGAAACCCTAAGGCCAATCAGTGTTGTCTCTTATGGTAATGTACCGCCTGGTGAATTCGATGATGAGTCAAATCATAGGGAACTTCTCGACCTTGAGGCTGCTTCTAAAAACAAACAGTTTGTTAGTATGATGAATGAAAATTACTTTGGGGATAATATTTATGCTGATTATTTTACTTCAGACCGTGTGGAATCTTTTAGCAATGAGAGAGACACATTATCGCAGAAAGATGGCATTTACGGGATATGGGGGGAACCTTCACAGAAAGAGAATGAGTTTGTTCTGCCGAATTTCATTCATGAAAGTTATAAGATAGCTGAGAGTAATGAAACAGATTACACTGAGATGGACCAAGAGCGATTGGGTGATGGGGATGGTGATGTTTGTGAGAGTGAGAGCAAAGCTGAGGTATTAAGCGAAAGTAGAAGCGAGAGTGAGGTGCCATTAAACATCTGTGCGGATGAGCGCATGCCTCCTCGAGGTGAGCTCAGTGGGCAAGAGAGCAATGGAGACATGGAGTCACCTTGGAGTGGGATGTACCCAGAAGTGACGCCGTCGGAGCCCTACGACCTAATAGCACGCGAGAGTTGGGTCTCTGACGGATCAGATGTGGACGCAAACGAGAAGAGGGAACCTCTAGATGAAGAACTTCATTTTCCGAAAAGCCGAATGCACACTTGTGTTCAATGCAATGCAAAGTTTCCATCGGCTAAGGAGTTACGAACGCACAAGAGCGTTGCGCATGCGCTGCCTACGTGCTCCGTCACCAAAACGACGTACAGTCGTATGGTGACCGCCAGAGCGATCAAGAAGGAAGAAGAAGTCAAGACCGATGACAATATGTTGGCTTGTAGCATAATGGCGTTAGATTCCAAGGAGTCGATAACGACGACCATACTCCAAGCGTACGACATGGAGGACACGAAGGCGAAGATCGAGGGCTTCATAAAGCAGGAGACGAAGCGACGGCGGAAGGATTTCATTTGTCCGACTTGCAAAGTCGATCAAGTGACAGATGCGGCCTTCCATGCGCATCTCAAGATACACCCCCTCGAGTGTCTCACCTGTGGGAAGTGTTTCTTCAGGCGGGCGAACCTAGCACTGCATATAAAAACGCATTTAGGCATTAAGAATTACAAGTGTGAGGTTTGTGAGAAACGGTTCGTGACGCGGCAGAAGTTGGCGGAGCACCACAACGTACACACCGGTCGGGCGCCTGTCAAGTGCACTCTATGTGATGACACCTTCCGGAGATACTCCAACATGGTGCAGCACAGGGACCGACATCACTTCCAGAAGCGCATGAAGGTTCGCGACTTCGTGTGCCAGTGCGGCGCCGTGTTCCACTCGCGCGCGAAGCTGCTCTGGCACAAGGAGACGCACGACGACAAGCCCAAGTCGTGCCCCTACTGCAGCGACAAGTTCGTGCACGCGGCCTCGCTCACCCGACACATGCGTCGCTCCCACAACGAGTACTACCTCTCCGAGAGGCTCAAGGGGAAAGTCGACAACGTGCCTTGTCCCATCTGTAAACAGGTGTACCTAAGAACAAACCTACGATCGCACTTACAAACGCACAGCGGCAAGCGGCCGTACGTCTGCGTCGTCTGCAACAAAGCGTTCACAACGAAGTGGAATCTTAAACTGCACCGTTGGACTCACCTCAGTCGATCAGCTAAACCGTTCAAGTGCCACCTGTGTAAAGGCGCCTTCATCCGTCACACTGAGTACGTGTCGCATATGAACGCTCACAAATCCGTACGTCCGTACACGTGTAACTATTGCGGCTGCCAGTTTATAAGGAAGTACAACTGTCAGCGGCACGTCAGGGAACACGAAATGGCGAAGAAGTACGTGTGCAAGGTGCCCGAGTGCGGTAAGTCCTTCCACAGGAGTTACTATCTATCGGAACATATGAAAGTGCACAGCGGAGCGCGACCGTTCGCTTGTAATATCTGTGGTAAAACGTCTAGCAATAAATCGAATCATAATAAGCACGTTAAGATACACCACGCAAGGGAACCGGTCGCTACGGAAGCGTAA
Protein Sequence
MDQLVQCPVCTLYLHNGITLESHLDTHPKDQVIKALCSLATSKGNYTSRTSSPLHSERSYRSRSRTPATEDKWNGSHRPGEHERYWRRTPSRTPKSTTSTSISRNGTPDMKITDGLAFESAASGHNSLSSYALKQDKLQQTFQNSSMSDFEQTGGYYQDTQDDREIKYSRSTEYNTMDNANGVFTYNVQSPGSGLRYPTHSSLISNIPGRKGSGFIKIVQKPNNIFVKTDTGGMQYLQGAKPMHVMVPGTQTYVQKNMQNNMMIPGSISQSQVQIDPKGVPQQLTGNQFNQFTTGSYTPGLSTVVTQNSQIIYREMLHNIDGKQFISSVPAVIPTGPDNLPNTPQTASMYQNLMVVDQFGSCMYTNPQQVLPKPGTPTMYADSGTLVPSMHMSKTPVPAINDPKTLIIEVSPIVNPEQAASCSVLNDHVPDTTTRADKLNEPEMEKVENKCEASVSTKGLKILSNIKVEVPVQHNKNMINTIMDLTGPSDPEYSKKEDYSESPEKVLSKLEEKKENIIDDNTQPSNSSIDSVVSHAFSVIKNVGNPSSQKDSSSKSLDSKLDTDYGDSCPVPDLICNEKASISPCSELSESGENSTDRTSISSKVETDNSQFCESIESVEKKVQLPNKPNRLNLLRLNNIYVKKNKKVLKIKNSKQNSDKSLSIIDTEPVPSSSSEKSPENFAINKVHRVEMSVERECSTLHTVSVEEIKQNENNDESNEKNDFDADTEEQAMDIEPISPSQLRTTEFITQVDMVQVKEEISTSNEGGFSNETAASERILTPLETLRPISVVSYGNVPPGEFDDESNHRELLDLEAASKNKQFVSMMNENYFGDNIYADYFTSDRVESFSNERDTLSQKDGIYGIWGEPSQKENEFVLPNFIHESYKIAESNETDYTEMDQERLGDGDGDVCESESKAEVLSESRSESEVPLNICADERMPPRGELSGQESNGDMESPWSGMYPEVTPSEPYDLIARESWVSDGSDVDANEKREPLDEELHFPKSRMHTCVQCNAKFPSAKELRTHKSVAHALPTCSVTKTTYSRMVTARAIKKEEEVKTDDNMLACSIMALDSKESITTTILQAYDMEDTKAKIEGFIKQETKRRRKDFICPTCKVDQVTDAAFHAHLKIHPLECLTCGKCFFRRANLALHIKTHLGIKNYKCEVCEKRFVTRQKLAEHHNVHTGRAPVKCTLCDDTFRRYSNMVQHRDRHHFQKRMKVRDFVCQCGAVFHSRAKLLWHKETHDDKPKSCPYCSDKFVHAASLTRHMRRSHNEYYLSERLKGKVDNVPCPICKQVYLRTNLRSHLQTHSGKRPYVCVVCNKAFTTKWNLKLHRWTHLSRSAKPFKCHLCKGAFIRHTEYVSHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVPECGKSFHRSYYLSEHMKVHSGARPFACNICGKTSSNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01317635;
90% Identity
iTF_00114374;
80% Identity
-