Basic Information

Gene Symbol
Prdm14
Assembly
None
Location
GWHABGR00000047:14261224-14265668[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00027 0.018 15.7 1.8 3 23 44 65 31 66 0.95
2 10 0.37 24 5.8 0.2 3 23 88 109 86 109 0.93
3 10 0.00042 0.027 15.1 1.5 2 23 132 153 131 153 0.97
4 10 0.00028 0.018 15.7 0.2 1 23 157 179 157 179 0.98
5 10 0.0013 0.088 13.5 0.1 1 23 184 207 184 207 0.92
6 10 2.9 1.9e+02 3.0 0.1 2 20 214 232 213 236 0.77
7 10 6.8e-06 0.00045 20.7 0.8 1 23 243 266 243 266 0.97
8 10 0.017 1.1 10.0 3.1 1 23 272 294 272 294 0.93
9 10 5.6e-07 3.6e-05 24.2 1.4 1 23 300 322 300 322 0.99
10 10 5.9e-06 0.00039 20.9 3.6 1 23 328 351 328 351 0.98

Sequence Information

Coding Sequence
ATGGAAATGCTGCAAGCTCAACAACTATACAGAGAAAGAGACCCAACGTATATGACAGAGACGAATATACTGACAATAGTGGAGTTCTCCCACGTGTGCCCTTTCAAATGCAGACACAACCACCTACTCTGCTACTACTGCGGAGAGAACTTCTCAGATCCTCAACTCCTGAGGGATCACACAGCAACAGTCCATCATCCAAAGAAATTCAAAGTGACGGAACACAAAAACATGATCAAAATCGATTTGACCCGTATCGATTGTCGATTATGCTCAACCAAGATCGATAATCTCGAGGAGTTCAAGAAGCACATCGTATCAGCACATAAAAAGAAGTACTATTTCGATTACAAGGATTCAGTTCTACCGTTTAAGTTGACTAAGGAAGAGATAAAGTGTGCGATATGTCATCTAATATTCCCATACTTCCACGCTTTGAACAAACATATGAATGAACACTTCAGTAATTATGTTTGCGAGACCTGTGGTTTAGGCTTCGTAGATAAAGGTCGTTTCGTGATGCATCAGCAGCGTCACGACCAGGGTGACTATCCTTGCGACACGTGCGGGAAGGTGTTCAAGGCGGAGTACAACCGGGACCTGCACATCGACCGGGTGCATAGGAAGCGTGGTCGGGTCTACTGCCCCAAGTGCGACATCAAGTTGATGTCCTACCCTCAGAAGCTGAAGCACCTGGTGGAAGCGCACGGGGAACAGCCGATGAGTTTCCCCTGCACCATGTGTGAGAAGATATTCGAGACGCGTCGGACCCTCACGATACATCTCAGGAAGGACCATCTGAAAGATTACAGGTATGAATGTCAGTGCTGCGGTCAGAAGTTTTTCACACGTTTTGCTCTGAACAATCACATGCCTACGCACACCGGCGAGAGGAACTTCAAGTGCAAAGTCTGTGAGAAGAGTTACCCGCGGCTGAAGACCTTAAAAGACCATATGAGGATACACACGAACGACAGACGTTACCGCTGTCATATATGCGGGCAGGCCTTCATACAGAACTGTAGCCTTAAAGGACATATGAAGAGCCAACATGCCGAGTACGGATAA
Protein Sequence
MEMLQAQQLYRERDPTYMTETNILTIVEFSHVCPFKCRHNHLLCYYCGENFSDPQLLRDHTATVHHPKKFKVTEHKNMIKIDLTRIDCRLCSTKIDNLEEFKKHIVSAHKKKYYFDYKDSVLPFKLTKEEIKCAICHLIFPYFHALNKHMNEHFSNYVCETCGLGFVDKGRFVMHQQRHDQGDYPCDTCGKVFKAEYNRDLHIDRVHRKRGRVYCPKCDIKLMSYPQKLKHLVEAHGEQPMSFPCTMCEKIFETRRTLTIHLRKDHLKDYRYECQCCGQKFFTRFALNNHMPTHTGERNFKCKVCEKSYPRLKTLKDHMRIHTNDRRYRCHICGQAFIQNCSLKGHMKSQHAEYG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01316650;
90% Identity
iTF_01316650;
80% Identity
-