Amun034432.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anorthoa munda
Gene Symbol
-
Assembly
GCA_945859655.1
Location
CAMAOM010001173.1:89066-90604[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.00063 0.076 14.6 1.8 1 23 62 85 62 85 0.93
2 7 2.3 2.8e+02 3.4 0.1 2 23 112 134 111 134 0.88
3 7 0.19 22 6.9 0.4 2 23 157 178 156 178 0.96
4 7 0.00021 0.025 16.2 0.2 3 23 184 204 183 204 0.97
5 7 0.0011 0.13 13.9 1.5 1 23 209 232 209 232 0.97
6 7 0.01 1.2 10.8 1.0 2 23 240 262 240 262 0.89
7 7 5.6e-05 0.0066 17.9 1.2 1 21 268 288 268 289 0.95

Sequence Information

Coding Sequence
ATGTTAGGTACCGACCCGGAATCCATACTGATCGAGATAGAGGTCGACACATCATCATATTTCACTTCAGGCGAAGTGTCTGAAGTCTCCACACTCAGTGAAGTCGATAAACACAGAGCGAATATCCGAACTATCCTCCTTGCGAGCaacgccacgccgatcggaagatacgggagtctcgggtacaactgctgctactgcaccgaggtcttctcagcacccagggacctcaaaaagcatacaatcgaacgacacgatgaagaaaacatctcctcgtacatgaataactacactatgcttaactacatcgtcaaagtagacatcacaggcctccgctgtgaaatgtgcatgaaacctttcaacgaactccaaggaataattgatcacctcacgatagagcaccagaaattcttccacactgatattcggagtcacattgttccttttcggttcgattccgaggttctacaatgtgttgattgctcctccgaattcaacaacttcaagatcttgctcgagcatatgaattctcattacagtaacaatatctgcgagttttgcgatgctggcttcgtaaacagaagaatgctgcaagcccacatgtatagacacaaaactggagtcttccattgtgaatattgtgcaaaaatttttgatactcgtgtcaagatgaaagtgcacgaacgaatggtccatttgtacgttaaaaagagaccgaagtgtactatgtgtgagaggaagttcaaagacttccagaagatgatacggcatgaagctgaagatcatggtcttcagagaaagttcaagtgtgagatttgtagcagaatgtttactacagaaagatctttaaagattcacaAAAAGTTCTATTGTGTTTCTAATGATTAG
Protein Sequence
MLGTDPESILIEIEVDTSSYFTSGEVSEVSTLSEVDKHRANIRTILLASNATPIGRYGSLGYNCCYCTEVFSAPRDLKKHTIERHDEENISSYMNNYTMLNYIVKVDITGLRCEMCMKPFNELQGIIDHLTIEHQKFFHTDIRSHIVPFRFDSEVLQCVDCSSEFNNFKILLEHMNSHYSNNICEFCDAGFVNRRMLQAHMYRHKTGVFHCEYCAKIFDTRVKMKVHERMVHLYVKKRPKCTMCERKFKDFQKMIRHEAEDHGLQRKFKCEICSRMFTTERSLKIHKKFYCVSND