Basic Information

Gene Symbol
-
Assembly
GCA_945859655.1
Location
CAMAOM010000167.1:1418254-1421186[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 2.2e-06 0.00026 22.4 1.5 1 23 24 46 24 46 0.97
2 10 1.5 1.8e+02 4.0 1.7 2 23 52 74 51 74 0.91
3 10 8e-08 9.6e-06 26.9 2.3 1 23 78 100 78 100 0.98
4 10 2.8e-06 0.00033 22.0 1.0 1 19 106 124 106 127 0.96
5 10 0.00013 0.016 16.8 0.4 2 23 139 160 138 160 0.95
6 10 5.4e-06 0.00064 21.1 5.5 1 23 166 188 166 188 0.98
7 10 2.1e-07 2.5e-05 25.6 0.5 1 23 194 216 194 216 0.98
8 10 4.9e-06 0.00059 21.3 4.4 1 23 222 244 222 244 0.97
9 10 7.3e-06 0.00087 20.7 3.3 2 23 251 272 250 272 0.98
10 10 0.00011 0.014 17.0 3.9 1 23 278 301 278 301 0.94

Sequence Information

Coding Sequence
ATGAACTTCATAAGATCGAAAGAGCACTACTCGGATGAAGAAACCTTCCCCACAACGCCCTCAGGCGGCTTCCACTGCGAGATATGCAGAAAAATCTTCGTCAACTCCGGCAACTTAAAACGACACTTACTACTCCATAATAAAGACACAATCAAATGCCCTCAATGCAACGGTCAGTTCCTGAACCAAACCCGTTTAGACAGACATATATATCACCGGCATACGAAAGACTACCCGTGCGATCAGTGCCCTAAAAAATTTAAGACATCTTCAAACTTAAATCAGCATAAAAAAACACATTTAGTCAAGAAACCATACCAATGTTCCATGTGCCCTCAAAGTTTCTCTTTTAAGAGCAATTTGAAAAAACACGAAGGCAAAAAGCGCTGTAAACGGCCTTCCGGAGAGCCTTTAATATGTACAATCTGTAATAAGATCTTTGAAAAGGAGTATCTGTTGAAATCTCACTTGGTCAAGCATGATCCTGACAGACCTTTTTCTTGTGACGAGTGTACTATGAGTTTTAAACACAAAAGCACTCTTATGAGGCACATGCATGTCCATAACGGCATCAGACCGTATCCTTGCCCACACTGTGGGAAGACTTTCACCAGCTCTGGTCTCCTAAAGCCTCATCTAAGAGTTCATACGGGCGAAAAACCTTACACATGCGAGCTTTGTGACAGGAAATTTGCTCACAAACATAATATGCAAAGACACATGTTAGGGCACGAGAAGATAAAACATACAAAGTGCGATATATGTCACAAAGAGTTTCCAAGAGAGAGTAGACTTAAATATCACATGAAAACTCACGTAAATGAGAAGTATTTCTTATGCAAAGTATGTCCGAAACGGTTTTCGCATAAGCAGAATGTTATACGCCACTATAGTAGGAAACATCCAGGACAAACATACAGTTGTACTGAAACGGATGCAACTGTAGCTGCAATGGTTTGGGATACTATGAAGCCAAGATTCGAGGATGATGAACCGGAAGAAATTTTGGGTTGA
Protein Sequence
MNFIRSKEHYSDEETFPTTPSGGFHCEICRKIFVNSGNLKRHLLLHNKDTIKCPQCNGQFLNQTRLDRHIYHRHTKDYPCDQCPKKFKTSSNLNQHKKTHLVKKPYQCSMCPQSFSFKSNLKKHEGKKRCKRPSGEPLICTICNKIFEKEYLLKSHLVKHDPDRPFSCDECTMSFKHKSTLMRHMHVHNGIRPYPCPHCGKTFTSSGLLKPHLRVHTGEKPYTCELCDRKFAHKHNMQRHMLGHEKIKHTKCDICHKEFPRESRLKYHMKTHVNEKYFLCKVCPKRFSHKQNVIRHYSRKHPGQTYSCTETDATVAAMVWDTMKPRFEDDEPEEILG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-