Agla006612.1
Basic Information
- Insect
- Anoplophora glabripennis
- Gene Symbol
- Thap1
- Assembly
- GCA_000390285.2
- Location
- NW:86324-104921[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.58 18 5.8 1.9 1 23 352 375 352 375 0.95 2 25 0.19 5.7 7.3 0.3 3 23 393 414 392 414 0.89 3 25 0.066 2 8.7 3.4 1 21 420 440 420 441 0.95 4 25 0.86 26 5.2 1.9 2 23 476 497 475 497 0.97 5 25 1.5 47 4.4 0.0 3 23 511 531 510 531 0.96 6 25 1.7e-05 0.00051 20.0 0.9 1 23 537 560 537 560 0.95 7 25 0.0031 0.097 12.9 1.7 1 23 566 589 566 589 0.97 8 25 1.3e-06 3.9e-05 23.6 1.6 1 23 595 617 595 617 0.98 9 25 0.099 3 8.2 6.7 2 23 645 667 644 667 0.94 10 25 0.013 0.39 11.0 1.9 2 23 675 696 675 696 0.98 11 25 0.31 9.6 6.6 0.2 2 23 705 726 704 726 0.94 12 25 0.00076 0.023 14.8 0.4 2 21 733 752 733 755 0.89 13 25 0.00026 0.008 16.3 3.3 1 23 1155 1178 1155 1178 0.97 14 25 1.1 34 4.9 0.6 1 21 1194 1214 1194 1217 0.75 15 25 0.0021 0.064 13.5 0.7 1 23 1230 1253 1230 1253 0.95 16 25 0.0011 0.035 14.3 0.3 1 23 1255 1277 1255 1277 0.96 17 25 1.4e-05 0.00043 20.3 0.6 3 23 1283 1303 1281 1303 0.91 18 25 0.018 0.55 10.5 6.5 3 23 1311 1331 1309 1331 0.96 19 25 0.036 1.1 9.6 1.5 1 23 1337 1360 1337 1360 0.97 20 25 6.2e-05 0.0019 18.3 7.3 1 23 1366 1389 1366 1389 0.97 21 25 8.9e-05 0.0027 17.8 0.3 1 20 1395 1414 1395 1415 0.96 22 25 1.6e-05 0.0005 20.1 0.5 2 23 1443 1464 1442 1464 0.97 23 25 0.002 0.062 13.5 2.9 1 23 1470 1492 1470 1492 0.98 24 25 9 2.8e+02 2.0 0.8 1 19 1497 1515 1497 1520 0.87 25 25 0.009 0.27 11.5 2.5 1 23 1526 1549 1526 1549 0.92
Sequence Information
- Coding Sequence
- ATGCAGTGCAGAACGTGTTTACAAAAATTGACATGTCGTAGGTTGCCCCTTAAAATGAGAGTATCCTTTGGGAAAACTGTGGAAGaaatactacaattttttatcccaggaatgGTTAAATCGAATTTGGTCGACGATTTCATATGCCCTAGTTGCCTGGATGCCATAGAGGTATTTctgaagtttattaaaaaatgtatggacgttgaaaatttcttaaaagGGGAGATTGTCAAACAGAAGCAAGCACAACACAATGTTGATGTTTCAGACTTGGAAAATGAAAATCGAGTTAAAGAGGGTACAAGTGTTAATCGAAACAACGTAAATTatgACAACTTGAAGAAGAAATTGAGGGATCGGCTGGATGAATTATTGAAAGATCCAGCTCGAGATAGAGAAAGATCGAGAAAGGGACTGCAGCTGCCTTTCAACGAAGAGATAGGTTTTATAAAACCGCAGAAGACTTACCCTTGTAAAAAACGGAGTCCTCAAAGATCACCTGCCAAAGAgcTGCTACTTGAAATTCCTGGATCAGATTCTGATGCAACACCAATTTCGAATCCTAAGATCTCTCCCGAGGATATAACCGTCGCTTCCGAAAGACAGAAGGACGTTACTTCTACTTTTGTAGGGGGAAGTGCGAGTGCGATATGCGAATCGTGTGGTGAGAAACTTATTTCTGATAGTTGTAGTAACACGAAATGTGCCAATTGTAAGTCAAAAAAAGATGTTCAAACGGAAGGAAATACAAAACGTACAGAAAATCcgttgatttttaaaaacaatccGTACATCGAACTTGGAGAAGCCAACACGAACAGGCCAAAAATGTACTCAACGGTCATCTCAGAAAACGGCACCTCTTTGAAAATAGTCCTCCCAGCAGCATCTCGTTCAATCGTTCGTAATACCAGTCGCGTAGTAAGTATCGTCACGAACGAATCGAAATCCGACTTCCTAAAAAACTGTTTCCAACACATCAACTTGGTGAGGGTACGTTCGCAGCATGAAACGAACCCGAAACGAATACTCTTCCTTGGCGACGCCCTCCATTGTTGTCCGGAGTGTAAGGAATGGTTTCCGTTGAAACAGTCCCTGAGGGCACATTTCAAGGTGGCACATCCGGGCTGCCGGTACACATCTCACCCTAAAACGCTCAAAGTGTCTAAGGATTGTCCGGTCTGTAACGAGAAGTTTGGCACGCACTTGATGTTAGAGAACCACGTTGTCCTTCAACATAAGGAATCGTATCTTTATAACTGCGACATGTGTAGGAGGAAATTCAAGAGGTTCTTTAGTTACAAGGAGCACCTCAAGAGCTATGAGTTGTACGGGGACTGCACCGTTAAAAAGTGCCCCATCTGCGAACAGTTGGTTAACAAGGCCTCGTACTTGAAGCATTGCAAGACCCACCAGACCATCAAGTGCGACCTTTGTAAGAGCAAGTTCATGTCCCGCGCTCGTTTCAACGCCCACCGGTCGAAGCACCAAACCTGTGGACTAGCCGTAGAGAAAGAGAAAGCTCTTTGTCCCGTCTGTGGCGAATTGGTGACCCGTGGGGCTCCGCTGCGAATCCACATAGAAAATCACACGGAGACCCGTAGTTATCTCTGCGACAAATGTACAAAGTCCTTCAAGACGAACGGCAGCCTTCTTAGGCACATCGAAAAGGTGCACATAGATGGTAAACGGTACGAGTGCCCGATATGTAAGGCAACGGCGAAACACATGTATTCGTTGAGGTACCACATGCGGTTGAAGCACATCCAAGCTTATTCCTACGTGTGTGACAAATGCGGGAAAGGTTTTTCCCGTACCGACTACTTCCAGAGACACATTAAAAGTCACTTGGACGCAAAATGTGGCGATTCCGGCGATCGACGAAGGAAATACCGTTACATCCCGCCAAATTCAACCGACCTGGCCATCTCTTGCAAGTATTGCAATATGAGGTTTACTCACGTTCATAAGCTTCGGGTGCACCTGCTCCATAAACACTTGACGAATTCCGAGAGGCCCAAGTGTCTGTACTGCGACATGACGTTCTCGAATATCAGGAATAGGATCAGGCACGAGAAGAGACATAGAGATCCCAAGGCGTTCGAGTTGACCTGTAACGTTTGTTACAATCGGTTCGGGAGTAAGGCGGATCTGGACGCCCATTCCGCTAAGCATAAGGAGTCGCAGAAGCGGGTATGCGAGATTTGCGGGGAGACGTTTCCGAGTAAGTATTTCCTGCAACACCACGTGGGGGAGAAGCACTTCGACAAGGCGAAGGTTAAAAACGAGAAGAGCGCTCTGTTGAAGGAAGGTTTGAGTCATGTGATTATAAAGCCAGCCTTCGAACAGCCTAAAATCAATGTACAATTGTATAGAAGTAACAGTAAACAAGGGAATATTATAAATACCCCTTTTTTAGCTGGAGAATCAGCAGATTGGttacatggagttcgggctccttgtatAGTCTCCATGCTACAAACTATGAACAGTGCCTCCTGTCGTTGTTTTGTGCCGGGATGTCCAAATTCAGAAGAAAATTTAACGGATGCAACATTCCACGAATTTCCCGAAGAATTACAAGGAGAATGGCTCACAGCAATAGGTAGAAACAGAGATACTTACATCCTACATGAGCTTGTCTGCTCAGAACATTTTGAAAGCAACGACTTTGAATGTTACGATTCGATTAAGATATTGAAGCAAAACGCACTACCCACTTTAAATCTACCTGTAGAGCCTGACACACCTTCATTTACACCGAAACCCCAGGTGAAAGTCATCACGGGTAAAGAAATAAAACAGTTAGTTGAAAAATACAATTCTCTTGAGAAGAGCAAGCCTATAGAAATGTCAAGCAAAGCCGTTTGCACTGTGCTCAATCCTAGCTCAGACGAAAGTTGTAAATATGAGACCGCACAATTAAACACAATTAAGGTGATAGTTGTTACTGATAAATCGCAAGAGCAATCAGGTGGATTGAGTGTAGCTGAAGACACAGCGAATCTGTTGGAATGGAGCGATCAAGAGAGCGTGGAAGAATATCTTGTGAAACACGAAGACATTCTTAATTGCCGAACGTGCCTCGACGAGATAGACCCGGAAGGGGGCTATCTCGTCACAGACGTACACCACGAGAATAAAACTTTGAAAGAGATGATCGTTTACTGTATCCCTCAAATGACCTCGTCTCTCCTGGATACTGATCTAATCTGCAGCAAGTGCTTGGAAAGCATCAAATTCTGTACGAGCTTCATAGAAAACTGCTTGAAGGTAGAAGAGGAAATGAAGGAAAACCACTTTTTGGAAAACGGTGATGGCGACAACGTCGAGGATTCTCACAAGAATGGCGTGCCGGAAATGTTCCGACACATTCCACTGGACCATAACTACATACCAAAGACGTCAGACGACATCGTACAGGAAACTTGTGTGAAGTACGATCCATTGACGATGAAGCATGAGTGTTTGAAATGCGAAAGGACGTTTAAAACTAAGAACTATCTACTTGATCACATCCGGCGGTTGCATGGCTCAGGCGACAGGCCCGAGCCGAAGAAGAGGAAGACTTGCCCGTTCAACTGTGATTTTTGCGATAAATCGTTTCTGACCAAGCTGGGGTACGACCTGCACCTGCTGCTCAGCCACCCCGACCAACTGGAGAAGAAGAAGGAGCCCGGCGGTTACACCTGCAAAGATTGCGGGAATCGTTTCGAGACTTTCAGCGGTCTCTCGGAACACAAGGCGAAAGAACACGGTTTCGCTTGCAAGATTTGTTCGTTGAGATTCGACACGATGAGTGAACTGAACGCCCACTACGATTCCCATCCGAACGAGCACCTGTGCGAAGTGTGCGGCAAGGGCTTCAAGAGCAAAGCCAACCTGAAGGCCCACATGCCCACCCACAATGATCCCAACACGCACCTGTGCCACAAGTGCGGACAGGGCTTTAAGTCGCACGTGTCGTTGAGCCTCCACCTCAAGCGTCACAACCCCGACCTGAAGTTCCAGTGCGACGAGTGCCCCTCGTCCTTCCAGAAGAGGTACAGGCTCGAGTTGCACAAGAAGGTGCGGCACTTGGGGATACGGGAGTACAAGTGTACCGTTTGCAACAAGAGGTTCTGCTATAAGTCCAACCTGAAGAGCCACTATAAATTGAAGCACTCGGAAGTAAAACCTTATCAGTGTGAACGATGCGGGATACGTTTTGCCAGATCGGACTATCTGAGGAGGCACACCAGCTGCAGCGAGAAGTCGAAACAAAGGGATTTTGCGTCACACAAGAGGAAATATCGGTACAAAAGGGGAGATCTAGctGTAATCACGTGCAAGTTGTGCGGTAAGGTATTCAAGGATATCCAGATGCTTCGTTTGCACATAAAAACCCACACGAAAGTCAGAAAGTATAAATGTAAGACGTGCAACTTGACGTTCACTACGAGCAATAACAGGGACAGGCACGAGAAAGTGCATGAACACTGCACGTTCAGGTGTGAAGTCTGCTTCAAAAGGATGGAGACCCAGGAGGCCTTGGACGATCACTGCGCTGTAACCCACGAGAATTCCAAGAAATACAAATGTCATGTCTGTGACGAGTTGTTCGGCAGGAAATACCTTCTGCACAGTCACGTGGCGGAAAAGCACGGAGATGTGGAGGATTTTGAAAAGGAGAGGGAGGTTCTCTATAAAGTCGTTATGCAGGATTATTTGGTTGACGAGTGA
- Protein Sequence
- MQCRTCLQKLTCRRLPLKMRVSFGKTVEEILQFFIPGMVKSNLVDDFICPSCLDAIEVFLKFIKKCMDVENFLKGEIVKQKQAQHNVDVSDLENENRVKEGTSVNRNNVNYDNLKKKLRDRLDELLKDPARDRERSRKGLQLPFNEEIGFIKPQKTYPCKKRSPQRSPAKELLLEIPGSDSDATPISNPKISPEDITVASERQKDVTSTFVGGSASAICESCGEKLISDSCSNTKCANCKSKKDVQTEGNTKRTENPLIFKNNPYIELGEANTNRPKMYSTVISENGTSLKIVLPAASRSIVRNTSRVVSIVTNESKSDFLKNCFQHINLVRVRSQHETNPKRILFLGDALHCCPECKEWFPLKQSLRAHFKVAHPGCRYTSHPKTLKVSKDCPVCNEKFGTHLMLENHVVLQHKESYLYNCDMCRRKFKRFFSYKEHLKSYELYGDCTVKKCPICEQLVNKASYLKHCKTHQTIKCDLCKSKFMSRARFNAHRSKHQTCGLAVEKEKALCPVCGELVTRGAPLRIHIENHTETRSYLCDKCTKSFKTNGSLLRHIEKVHIDGKRYECPICKATAKHMYSLRYHMRLKHIQAYSYVCDKCGKGFSRTDYFQRHIKSHLDAKCGDSGDRRRKYRYIPPNSTDLAISCKYCNMRFTHVHKLRVHLLHKHLTNSERPKCLYCDMTFSNIRNRIRHEKRHRDPKAFELTCNVCYNRFGSKADLDAHSAKHKESQKRVCEICGETFPSKYFLQHHVGEKHFDKAKVKNEKSALLKEGLSHVIIKPAFEQPKINVQLYRSNSKQGNIINTPFLAGESADWLHGVRAPCIVSMLQTMNSASCRCFVPGCPNSEENLTDATFHEFPEELQGEWLTAIGRNRDTYILHELVCSEHFESNDFECYDSIKILKQNALPTLNLPVEPDTPSFTPKPQVKVITGKEIKQLVEKYNSLEKSKPIEMSSKAVCTVLNPSSDESCKYETAQLNTIKVIVVTDKSQEQSGGLSVAEDTANLLEWSDQESVEEYLVKHEDILNCRTCLDEIDPEGGYLVTDVHHENKTLKEMIVYCIPQMTSSLLDTDLICSKCLESIKFCTSFIENCLKVEEEMKENHFLENGDGDNVEDSHKNGVPEMFRHIPLDHNYIPKTSDDIVQETCVKYDPLTMKHECLKCERTFKTKNYLLDHIRRLHGSGDRPEPKKRKTCPFNCDFCDKSFLTKLGYDLHLLLSHPDQLEKKKEPGGYTCKDCGNRFETFSGLSEHKAKEHGFACKICSLRFDTMSELNAHYDSHPNEHLCEVCGKGFKSKANLKAHMPTHNDPNTHLCHKCGQGFKSHVSLSLHLKRHNPDLKFQCDECPSSFQKRYRLELHKKVRHLGIREYKCTVCNKRFCYKSNLKSHYKLKHSEVKPYQCERCGIRFARSDYLRRHTSCSEKSKQRDFASHKRKYRYKRGDLAVITCKLCGKVFKDIQMLRLHIKTHTKVRKYKCKTCNLTFTTSNNRDRHEKVHEHCTFRCEVCFKRMETQEALDDHCAVTHENSKKYKCHVCDELFGRKYLLHSHVAEKHGDVEDFEKEREVLYKVVMQDYLVDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -