Basic Information

Insect: Anopheles ziemanni
Gene Symbol: ush
Assembly: GCA_943734765.2
Location: OX030919.2:16105166-16111753[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0063 0.49 11.1 0.0 1 20 317 336 317 338 0.92

2 9 0.0004 0.031 14.8 0.7 1 23 407 429 407 429 0.98

3 9 0.024 1.9 9.2 1.4 2 21 512 531 512 532 0.92

4 9 0.066 5.1 7.8 3.3 2 21 975 994 974 995 0.94

5 9 0.003 0.24 12.0 0.0 3 21 1058 1076 1056 1077 0.91

6 9 0.0026 0.2 12.3 0.0 1 23 1127 1149 1127 1149 0.99

7 9 0.016 1.3 9.8 1.4 1 23 1155 1177 1155 1177 0.99

8 9 0.63 49 4.8 4.5 1 23 1263 1286 1263 1286 0.95

9 9 0.38 29 5.5 0.7 2 21 1470 1489 1469 1490 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0063	0.49	11.1	0.0	1	20	317	336	317	338	0.92
2	9	0.0004	0.031	14.8	0.7	1	23	407	429	407	429	0.98
3	9	0.024	1.9	9.2	1.4	2	21	512	531	512	532	0.92
4	9	0.066	5.1	7.8	3.3	2	21	975	994	974	995	0.94
5	9	0.003	0.24	12.0	0.0	3	21	1058	1076	1056	1077	0.91
6	9	0.0026	0.2	12.3	0.0	1	23	1127	1149	1127	1149	0.99
7	9	0.016	1.3	9.8	1.4	1	23	1155	1177	1155	1177	0.99
8	9	0.63	49	4.8	4.5	1	23	1263	1286	1263	1286	0.95
9	9	0.38	29	5.5	0.7	2	21	1470	1489	1469	1490	0.92

Sequence Information

Coding Sequence: ATGTACTTCGTACGAGACGGAGATGAGGAAGCGGCCgacgaacagcagcagcagcaacagcagacaCAGGGAGTGGCGGAGGAAAATGGTGGCCCAATGCCGGCGGATACGACAGCGCACAATAGTGATAATGGTGGTGGCACCCTAGGAGGCAACAAGGAGGAAGGTGTGCGGAGTCGGAGCAGCAGtcggagcagcagcagtagccaCGCAACAACAgcgggaggtggtggtggggtgGGCGGTATGGCCAACGAAGAAGTCAGCATGAACGGTGCCACGACAATGGAAGACGCGGAAGCGGAAGACCGAAGCCCATCGCCGGCAACCACAACATCACCCTCCCCGACGGCGTTGGCGTCCGCGACAGCGGAAGACGAAAATTGTTTgcgatcaccaccaccaccaccaccaccgctggcAGGATTGACCACCGGTCGGAGGGTTTCGGAAGAGATGGTTGGCGGAATGCGCGAAATCAAGCTGGAACCCAACGTCGACCGGGAAGACGACAGTCAacaggaagaggaagaagggTTCGGCGATTATAAGCGACCGGCGGGGGAACTGCGACCACCGTCATCCGGGTCCTCGTCCCGGGGCCCAACAACGCCGTCGCCAACCCCGCTCCCGATGCTTCGGCTCAATGTAGCGCTGGCGTCCGATCCGGCCGCCAATCCGGACGCGAAGGATCTCAAGAACATTGGCGCCAGCAGCGAGGCCGCCTACGAGGAGAAGCAATCtcagcaccaacaccagcaccaAGCgctacaacagcagcagcatcacgtTCTCAGCATGGCGGTTATTGGCCATCCGCCGACGGTGTCACCATCGGCGTCCGCACCGACGGCGCTACTTTCCCGCAAGCAACCCCCGACGGGGTCGCTCGGCAAGGTCCCCGATGCCATCGCACTGCCCGTCGAGCTGCCACCCCGACTGCCGATGTACATCTGCGGACCGTGCGGGATTCGATTTTCCTCGGCGTCGACGCTCGAAGCGCATCAGACCTACTACTGTTCCCATCGGAAGGACGCGGACGACGGAggaggtggtggcggcggtggtggtggtggtggtggagcggGTTCAGTGAGTTCGGTGACGAGCAGTGGTAGCGGATCGGCGGCCGCTGGGAGTGGTAAAAATGCCCACCCGGGTGGAGCGGAAGGAGCGTCCGGGGAACCGCCGGCAAAGGCGGCCAAGACGGGAAAGCAGTACGCCTGCTCGCAATGTTCGTACAGCGCCGACAAGAAGGTGTCGCTGAACCGACACATGCGCATGCATCAGTCATCCCCCAGCCCTTCGCCGGTCGCGGCCGCTCTCGTCAACGGTGACGACCTCGCcggacaccaccaccatcagcagcagcaacaacaacagcaactacAGCTCATCCAGGCGCAAGCCGTTGCTGCAGCCGCCGCCGTACTTCACcaacaacaccagcaacaacagcagcagcagcaacagcaacagtcatcacagcagcagccacagcagcaacaggtgCCGGTGGCGCAAGTGGATCGGTACTGCTCCGATTGTGATATTCGATTTTCTAGCACCAAGACCTATCGCGCTCATAAACAACATTACTGCAGTTCGCGTCACCGTGAAGGGCACCAGTCGAACAACTCTACTCCGAAGCCGTCGGCTGGCCAAAAATCCGGTTCGCAGAGTCCACCGGATGTGCCGAAAACACCACCGGGGTCCGCTCCCCAGCAGGCGTTCCTGGCCCTTCCCACCAATCCCATCATCGTGGTACCATACTCACTGATCCGAGGTGCTAGCGTCATACCGGTACTGCTATCATCGCTTGCCCCGGGGATCGCCAATCCAGAGTCGGCCTGTTTCATCCTGCAGAACGGAGCACTGCAGCCGATCGCGATGTCATTGGCACACGTTCAGGCGGTTACGATGGCGGCCGCCGTCGGTTCTACCGGTCTCGAGGGGCTTGGAGGAGGGGTGCCTGGTCAGCATCCTCAaccacaccagcagcagcagcagcaacaacagtcgTCGGGTAGCTCGCGATCGACCGGAGGAAACAATAACCAACAACAATCGCGCGGCCCAACGCCCAACATATCGAATGAAAACAGTTCTCATAGTACCAGCGGCGGCGGGGTTGGCCCATCGTCCACCGGAGAAGTCCTGAAGGCAATCAATAAGCGTGACAATACTGCTAACAAgGAATCGACTGGGTCAACTCCTCTAGATTTGTCCGTAAGGCGGCTCTCTCCCGGTGCGTTAGGTCTTCGTGAGCGATCCCTATCGTTGTCCTCAGCCGTATCGCTGGACCAGCGCCTCGACTTTGACAGTCTGATGGAGGGCAAGGAAAATCTCTCCGTAAGCGGTGACTCGCTCACCCCGGAACAAATCGTTTGCGCCCCATCACTCCCCGGTAGCCCACCGCTGACTCCTTCGCCCAAGCGCCGCTCGAATAGTCCACGCGGAGGAGGAGGTTCTACTGCTGCTGGGGCACACGCAAATGCAGCGGCCGCCGCCATTGCAGCCGCAGCTGTCGCAGGACAGCATGCCGCCCTGGGTGGAAGTGCACTGTCCCTGTCTCCACTCaccctccagcagcagctgatGCGGCCACTGCTTCCAGCCGACATTGCCCTTCGATTGTCGGCCGTCGGAGCCGATCCGGGCGTCAATCTTAACCTCAACATCCTTCCCAACTCACACACGCTCCTGACGAAGCAGAGCGTCGAACTCGCCCTACGCCTATCGTCCACACCCGGTTCGGCGGCATCCGCCGTTCCACCGGGCGAAACACTGACGAAACCTCAGATATCCCCCCTCCTGAACAGTATCTCCCCGACGGGTGCTACCACCGGGGCCGGTGTAGGTGCGGCGGCCGGTGTGCTCTCCGGTCCCACGCCACAGATCTTCGTCAAGCAGGGTGACTCGAAGTGCAAGGAGTGCAACATCGTGTTCTGCAAGTACGAGAACTATCTGGCACACAAGAAGCACTACTGTTCGGCGCGCAATCAGGACGACGGAGACCATCCGAAGATCAGTCCACCGATCTCTCCGCAAGCGCATACCGCGAGCACAGCCCCAGGGGCTAGTCCGGCCGGGGCGGTGTCGTCCGGTGGTCCCGCAGCTCGCAATACCGTCGGCGTTGTTGGTGGACCCGTTGCGTACCAGCAACTGATATGTGCCGCCTGTGGCATCAAGTTCACCTCGCTGGACAATCTCACCGCGCACCAGATGTACTACTGTCCGAAGCGGATCGACGCCTCAATGCCAGTGAATTCCATTCCGACAAGTGTGGTCGCACCAACGCCACACAAAGAGCGTTGCTCCAAGTGCAAGAGTATGCACGAACCGGGTCAACCGTGCACGGTCGCTGGCCACGGTGCGTACAAGTGTCCGATCTGTGAAGCTATCAGCCCGAACTCCACTGAAGCCCGCCGGCACATGGACACGCACGGTGGCGTTAAGGCGTTCCGGTGCACGATCTGCCGTTACAAAGGAAACACCCTTCGTGGCATGCGTACCCACATCCGGATGCATTTCgataaaaaaacgaacgagTTCAATGAGGAAAATTACATCACCTGCATCCTGGAGGAGGATGGAATTGAAATCCCACCGGCCGGGGCACAGAACGCAGCTGCGATGGCCGCTGCCGCCGCGGCAATGGCGTCGTCGCAAAAGTTTCTCGACCAACAGTCGAGCGCAGCAGTGCACGATGCCGGTTCGTCGGGGCCACGCACTTCGCCACCGAATGGTGGTGGAAATGGAGCCACGGGCGGGGTACAGATGCGGCATCACTGCGAGTTCTGCCCGTACAGTTCGAGCTACCGGATCAATGTGGCTAAACATATCAAGCACGTACATGGACGAGAACGGCCTTCCACCGGCGGATCTCCGCTGATCGGCGAAGGAGGTGAATCACTGCTGTACAATGGCACTACCGGAGGCACGATAGAAATGGGCGGAAATATTCAGAGACCATCGGTTCCTAGTACTCCCGGACTGAGCGTGGGCAATAGTCACATCAAAACGGAACCGGAAGATGAACCTAccgtcggcggcggcggatGTGACGAGCAGGACACGATCGACATTAACGTGGACGTCGTGATGGAGGAACCGCCGTTGGCGGAAGGACCACCGATGGCCATCAAAACCGAAACCATCGATCCGCACATGCCCTCGCTGCACTCACCACCCGCCACCATCAGTACTCCTACAcccccaccacctccaccaccaccagcaccggcaACATCATCGACGACGCCGGTCGGCGTTTCCTTGAATCTGAAACCGAAATCTCATCCCGCCACCAACCGTTCGTCACCGTCTCCGCTTCTCTCGCTGAAAACGCCCTCACCGCCGACCAGCGAACCGATCACCCTGCAAACACTCCCGCCCGGGCCCAAGTACTGCGACACGTGCAACATCACCTTCAACTACACCAACACGTACATTGCGCACAAGAAGTTCTACTGCAAGGCAGCGACGGCCGCGGCCGGCTCTTCGGCGATCGGTGGAACCGGTGGTAGCGGTGGTGGGCGCAGTGCATCCGCTTCCCCTAGTCGGTCGGCGACCGGTGGAGCAACTAGTCCAGCCGTGGCGGTCGCAGTCAATCGAGCGACGGAAACATCCGTCTAA
Protein Sequence: MYFVRDGDEEAADEQQQQQQQTQGVAEENGGPMPADTTAHNSDNGGGTLGGNKEEGVRSRSSSRSSSSSHATTAGGGGGVGGMANEEVSMNGATTMEDAEAEDRSPSPATTTSPSPTALASATAEDENCLRSPPPPPPPLAGLTTGRRVSEEMVGGMREIKLEPNVDREDDSQQEEEEGFGDYKRPAGELRPPSSGSSSRGPTTPSPTPLPMLRLNVALASDPAANPDAKDLKNIGASSEAAYEEKQSQHQHQHQALQQQQHHVLSMAVIGHPPTVSPSASAPTALLSRKQPPTGSLGKVPDAIALPVELPPRLPMYICGPCGIRFSSASTLEAHQTYYCSHRKDADDGGGGGGGGGGGGGAGSVSSVTSSGSGSAAAGSGKNAHPGGAEGASGEPPAKAAKTGKQYACSQCSYSADKKVSLNRHMRMHQSSPSPSPVAAALVNGDDLAGHHHHQQQQQQQQLQLIQAQAVAAAAAVLHQQHQQQQQQQQQQQSSQQQPQQQQVPVAQVDRYCSDCDIRFSSTKTYRAHKQHYCSSRHREGHQSNNSTPKPSAGQKSGSQSPPDVPKTPPGSAPQQAFLALPTNPIIVVPYSLIRGASVIPVLLSSLAPGIANPESACFILQNGALQPIAMSLAHVQAVTMAAAVGSTGLEGLGGGVPGQHPQPHQQQQQQQQSSGSSRSTGGNNNQQQSRGPTPNISNENSSHSTSGGGVGPSSTGEVLKAINKRDNTANKESTGSTPLDLSVRRLSPGALGLRERSLSLSSAVSLDQRLDFDSLMEGKENLSVSGDSLTPEQIVCAPSLPGSPPLTPSPKRRSNSPRGGGGSTAAGAHANAAAAAIAAAAVAGQHAALGGSALSLSPLTLQQQLMRPLLPADIALRLSAVGADPGVNLNLNILPNSHTLLTKQSVELALRLSSTPGSAASAVPPGETLTKPQISPLLNSISPTGATTGAGVGAAAGVLSGPTPQIFVKQGDSKCKECNIVFCKYENYLAHKKHYCSARNQDDGDHPKISPPISPQAHTASTAPGASPAGAVSSGGPAARNTVGVVGGPVAYQQLICAACGIKFTSLDNLTAHQMYYCPKRIDASMPVNSIPTSVVAPTPHKERCSKCKSMHEPGQPCTVAGHGAYKCPICEAISPNSTEARRHMDTHGGVKAFRCTICRYKGNTLRGMRTHIRMHFDKKTNEFNEENYITCILEEDGIEIPPAGAQNAAAMAAAAAAMASSQKFLDQQSSAAVHDAGSSGPRTSPPNGGGNGATGGVQMRHHCEFCPYSSSYRINVAKHIKHVHGRERPSTGGSPLIGEGGESLLYNGTTGGTIEMGGNIQRPSVPSTPGLSVGNSHIKTEPEDEPTVGGGGCDEQDTIDINVDVVMEEPPLAEGPPMAIKTETIDPHMPSLHSPPATISTPTPPPPPPPPAPATSSTTPVGVSLNLKPKSHPATNRSSPSPLLSLKTPSPPTSEPITLQTLPPGPKYCDTCNITFNYTNTYIAHKKFYCKAATAAAGSSAIGGTGGSGGGRSASASPSRSATGGATSPAVAVAVNRATETSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -