Basic Information

Insect: Anopheles ziemanni
Gene Symbol: -
Assembly: GCA_943734765.2
Location: OX030920.2:68023043-68026166[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0054 0.42 11.3 0.3 2 23 237 259 236 259 0.95

2 10 8.7 6.8e+02 1.2 0.1 6 23 268 285 268 285 0.95

3 10 0.22 17 6.2 1.9 1 23 291 313 291 313 0.89

4 10 0.00037 0.028 14.9 0.2 2 23 322 343 321 343 0.97

5 10 2.7e-05 0.0021 18.5 0.6 1 23 354 377 354 377 0.96

6 10 4.5e-07 3.5e-05 24.1 1.9 2 23 387 408 387 408 0.98

7 10 0.017 1.4 9.7 5.0 2 23 416 437 416 437 0.97

8 10 0.0028 0.22 12.2 3.4 1 23 442 465 442 465 0.97

9 10 5.8e-08 4.5e-06 26.9 0.3 1 23 471 493 471 493 0.97

10 10 0.0004 0.031 14.8 3.4 1 23 499 522 499 522 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0054	0.42	11.3	0.3	2	23	237	259	236	259	0.95
2	10	8.7	6.8e+02	1.2	0.1	6	23	268	285	268	285	0.95
3	10	0.22	17	6.2	1.9	1	23	291	313	291	313	0.89
4	10	0.00037	0.028	14.9	0.2	2	23	322	343	321	343	0.97
5	10	2.7e-05	0.0021	18.5	0.6	1	23	354	377	354	377	0.96
6	10	4.5e-07	3.5e-05	24.1	1.9	2	23	387	408	387	408	0.98
7	10	0.017	1.4	9.7	5.0	2	23	416	437	416	437	0.97
8	10	0.0028	0.22	12.2	3.4	1	23	442	465	442	465	0.97
9	10	5.8e-08	4.5e-06	26.9	0.3	1	23	471	493	471	493	0.97
10	10	0.0004	0.031	14.8	3.4	1	23	499	522	499	522	0.97

Sequence Information

Coding Sequence: ATGGAGAAGATTTTTCACCGTCCAGTTGGATTACATTGGTCGGTGGATGAAGAGAAACCGCTACCGAAACACATTTGCCTGAACTGCTTGGAGACCGTGGAGGCGTTCGACAAGTTCTACACCGATGTTGCACAAAATCAAACGTTTCTCGCACAGAACGAAAAAACGACGGTTAGTGTACTGGTGTGGAACGAAGAGCATCTGGAGCAGGATGAAAGCGTGGAACATCATgacaaagaagaagaagttatcGAAGAACCTGTCGATCCGAAAGACAGCTTTATGCTGCATTGTGTCTCGGAGGAGGGTCCTTGCTTGGTTCCCGAAATGTCTCGCTCCCGATCGAACCCTCCGTCGTATGATGAGGTGCAGCAAACAAAACGTGCCAAATTGATTGATACAGGAACAACCACTCACGTTGTCGGTTCAAACGTTGCGGCAGATCGTCACTACATCGAACCAGGAGTAGAGGAACCGTGTCCTAGCAATGGTTTGAAGGTGATCGTTGGCACATTTGCTAACAGCGATGATGTTGCAAACGGGTCGGAATTGGAAACCGATGTTCAATGCATCCAAGAACGAACCGTTCAAAGTGCGGGTATCGTTGTCAAGGTATGCAACATCAAGTACCCAAGAATGATACGGGATGGCAAACTGGTGGTGAAAGGTGAGGTGCTCGACAAATGTATTGGAAAGTTTTACGGGCTGGAATGCGAATTGTGCAACGAGAAGAGCAGTACCATGGAGGAACTTTTCACACACTACCGAAACGTGCACAATGATGAAGGCTACGTTATGTGCTGTGGACGAAAGATAGCCAAACGTGTGCTTATGGCGATGCACATGGCGCGACATTTGGAACCCGAAGCCTTTGAGTGTCCACATTGCAAAAAAATGATGACCTCTCCACGCATCCTACGGTTTCACATTAGAAATCACCTGCCAGAGGAGCAGCGGCCATTGAAGTGTGACCTTTGTCCGCGACGGTTTAGTTACGTCAGTGGGCTGCTAACACATGCATCCACACACCAGACCGagaataaatcaaaccaaGCTTTTCACATCTGCGACGAATGTGGCCGAGCCTACCGAACCCGGGGCAGATTAACCGAGCACATCCTAACGTCCCACGCAGGTGACGGAAGCACAAATTGCGCCCGGTGTGATATTTGCGGGAAGAAGTTTTCGTCGAAAAGTACCCTCAGCTACCACATGACAACGCACGAACCGAATGTGCACCAAGAACAATGCGAGCATTGTGGAAAATGGCTGAAGAACAAAATCTGTCTGCGGAAACACATGCTACAGCACTCGGGCTTCCTCTACCACTGCGACAAGTGTGACTATTCGACCACAAACTCGCAGCGTATGCAGAGCCACCTTCGGGTGCAGCACACGGACGCTAAACCGTACGAGTGCCCGGAATGTGGCAAAGCGTTTAAACTGCGATACAACCTGCGCAATCACATGGCCCAGCATACGGGCGAGCGCAAGTTTACCTGTGAGTTCTGCTCACGTCAGTTCGCGTCGAGTAGCAACTACTACAGCCACCGGAAGCGTATGCACTCGGAGGAAATGGAGCTGAAAAGGAAACAGAAAGAACTGATGGATAGTGAAATCCGTATCAAACTGAAGAAAGTATAA
Protein Sequence: MEKIFHRPVGLHWSVDEEKPLPKHICLNCLETVEAFDKFYTDVAQNQTFLAQNEKTTVSVLVWNEEHLEQDESVEHHDKEEEVIEEPVDPKDSFMLHCVSEEGPCLVPEMSRSRSNPPSYDEVQQTKRAKLIDTGTTTHVVGSNVAADRHYIEPGVEEPCPSNGLKVIVGTFANSDDVANGSELETDVQCIQERTVQSAGIVVKVCNIKYPRMIRDGKLVVKGEVLDKCIGKFYGLECELCNEKSSTMEELFTHYRNVHNDEGYVMCCGRKIAKRVLMAMHMARHLEPEAFECPHCKKMMTSPRILRFHIRNHLPEEQRPLKCDLCPRRFSYVSGLLTHASTHQTENKSNQAFHICDECGRAYRTRGRLTEHILTSHAGDGSTNCARCDICGKKFSSKSTLSYHMTTHEPNVHQEQCEHCGKWLKNKICLRKHMLQHSGFLYHCDKCDYSTTNSQRMQSHLRVQHTDAKPYECPECGKAFKLRYNLRNHMAQHTGERKFTCEFCSRQFASSSNYYSHRKRMHSEEMELKRKQKELMDSEIRIKLKKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00096579; iTF_00107880;
90% Identity: iTF_00096579;
80% Identity: -