Basic Information

Insect: Anopheles stephensi
Gene Symbol: zld
Assembly: GCA_013141755.1
Location: CM023248.1:87039454-87043365[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0075 0.43 10.9 3.9 1 23 24 47 24 47 0.94

2 7 0.031 1.8 9.0 0.1 2 23 343 365 342 365 0.95

3 7 0.0034 0.2 12.0 2.9 1 23 622 646 622 646 0.92

4 7 0.51 29 5.2 5.5 1 23 1157 1180 1157 1180 0.94

5 7 0.048 2.8 8.4 5.2 1 23 1186 1208 1186 1208 0.97

6 7 2.8e-05 0.0016 18.5 6.7 1 23 1214 1236 1214 1236 0.98

7 7 2.4e-05 0.0014 18.8 1.0 1 23 1242 1264 1242 1264 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0075	0.43	10.9	3.9	1	23	24	47	24	47	0.94
2	7	0.031	1.8	9.0	0.1	2	23	343	365	342	365	0.95
3	7	0.0034	0.2	12.0	2.9	1	23	622	646	622	646	0.92
4	7	0.51	29	5.2	5.5	1	23	1157	1180	1157	1180	0.94
5	7	0.048	2.8	8.4	5.2	1	23	1186	1208	1186	1208	0.97
6	7	2.8e-05	0.0016	18.5	6.7	1	23	1214	1236	1214	1236	0.98
7	7	2.4e-05	0.0014	18.8	1.0	1	23	1242	1264	1242	1264	0.97

Sequence Information

Coding Sequence: ATGGCCAGTAATGGGGGGACTCTGCACGGGGTTCCCCAGAGTGtgtcacagcagcagcagcagcaacagcacatcTGCTCCCAGTGTGGCCTATACTTTGAGAGTGCGTCCTCGTTGCAGGTGCATCATATGCACTACCATCAGCATGACAGCATGAACCGTTGGGGTTCACAGCAGCAGCCCGTGGTCAGTACAACGCTCGGAACGACAGCGGTTGCAACGACAACAACGACCGCCACCACCATAACAACGAACGGGACCGCACCGTCCTCCACGACGCCAACGTCCTCCGACACGGAGAACAACAACCAGCCCGGTTCGCATACGCCGACGCACGCGACGGCTGGTTTGAAGCCGGTAGCGTCACCTCACACGACGATCGCGGCCGCCGCCGATTCGAGTGACAATCAGCCGCCAACGCCACAGCCCACCATAACGGAGCCTGGAACTCCGCAAAGTTACGGCGGTGGTGGCACATCGCCCTATCACtctcagcaacagcaacagcagcagcagcagcaacaacatcagcagcaagtAAGTCAACATCCGCATCAGCTAGGATTGCCCACGGGGTCAGCAGGGAGTGAGATGCACTATCCCAGCTACATCCATCCCGGGTACGATCCGGGCAGTTACTACTCCGGTGGACCTGGTTCGGGTCTTGACTACGGTGGCGGTGTACTAGGTGCACCTCTGCAACCTACGGACTATAAATCCGGCTCGTCGGTCGTGTCCTCGGCAAGGTACCATCCGTACGGCGGTGGTtccagtggcagcagcaacaacggcGGTGGTCCGGATGGTTCTTCGCCGGCGGTGGTTAGCAGCAACGGTGGTTCGGCCGGCATGAGTCCGCAAGTGGTAAGTTCTTCCAATGGTGTTACCGTAGCAGGTAGCGGCAGCGGATCCACGACTGTGACGACCGTCGCCAGCACCACTTCCCAATCGTCCCAGCCGGCCCATTCGCCACCGAACGGAACGGGCGGCTCGAACATTCCACCAACACCGTCCCCATCGCCGATCCAGTGCGAGAAGTGTGGTATGGTGTGCGAATCCGACGAGGCCCTGAACGAGCATGAGGCCACGATACACTCGAACGTGCAGTCGGCGCaagatcagcagcagcagcgcgtcGATCAGGTTGATCTgcagggtggtggtggaaactGTTACACGTACGGAGCTGGAGGAACAGGCGGTACGCCAGTGTACCCCGTGAAGGAAGAAGCGCCCGCTTCGGACATCCTCGATCTCGACTCGCAAAAGATGGTTGGTTATGGACCTGCGGGTGATGGTGGTCTGTTGCCACCGATGAACTCGCTGCATCCACTACAATCGATGCAACGACACCCGATGATGTCTTGGCATGATCCGCACAACTTCATGGGTCCTCCGTCACTTCCACCGCCGCATCCATCGCATGGTGGTGGGCCCGATATGAAGCACTCGGCcgccgtagcagcagcagcagccgcggCCGCCTATTACCATCATCCGATCAAGTCCGAGTATTCGGCTACTCCGGCGATAAAGTCCGAGTATCTTGGTGGCGGAGGAGGTGGACATTACGGTGGGACGGGTAGTCCGATCGTGAAGAATGAATACAGTCTGCCGCCAACATTGCCACCACCGGCCGTGGCTCCACAGCCAACGAACGCCCAGACGATGAAGCAGTACGCGGACGAGATGCACGACAATCAGCTGGCAACCAGTCCGTCCGATTTCCCGAGCACGACCACACCGCAGGAAAGTGGTTCGCAGTACCGTACGTTCGAGCCGGCAACTTCATCGCTTCCGGGAACAGCGGGACCCACGAAGGGCACTGCTTGGAAGTCGAACGAAGCGCGCCGTCCGAAGACTTACAACTGTACGGCGTGCAACAAGTGGTTCACTAGCTCGGGCCATCTGAAGCGTCACTACAACACGACGCTGCACAAGAATGCGGTAAAGTCGAGTGGCCAGCCAGATCCGGCGACGCTACCGATCAGCGTGCATCATCACCCGGGTCGTGATCCGAACTACGCCAACAAGGGTCGCCGAGGAGGAGCGGGCAACGGTTCCGGAGCCGGTGCTGGAGGAGGAGGTTCAGGTGGAGCTGGAGGTGGAGGAGCAGGTTCGCAGATCCAGCAGCCTATACAGCAGCCAGTACCACCGCCCGATCCACCGAGAAGTCCCGAGTACGGGACGGGTCCGGGTGCGCAGCAGTACGGCAGCGCATCGGCGGCGGGGTTTTCGACGGCCGGGAACTCGCCCGGCCATCAGCATCCGGGCAGCGTGGGCCAGGTAGTCAGCTCGAACCAGTCACCGGGGTTTCATCACCCGTACGCCGGCGCGACCAGCGCGAACGGCACCACAGCCAGCTCCACTTCTTCAGCGGTTCCCCCAAACGGGGTAGCAGGTCCCTCCGTCCAAGTCTCCCAACCGAGGGGCCTGCAGATCTActcgaacagcagcaacagccacaGCATGGCGGAGCAAATGGAGCAAGCCACCCATACCATTACCACCATCCTCACGCCCACCACCCATCCGCTCACCTCCACGGTGGGCATCCCGGACACCCTGGGCACCCGCAtctccaccagcaccacccgCACGCCCACGGACACCCACACGCCCCCCACCATGGGCATGGGCTCGCCGGTGGAccatctgcagcagcagccgcagccgccgcagcagcagcagccgccgccgcaGCACATCATCAGTTCAATGGAGCCCTACCACCACCCCCACACGCAGCCCCACACAATGCACACCATCTCCAATCCTTTAACTATCAGCACCAGCATTCCATCCTTCCAAACCATCCTGCCGGAGGCACCGAGCTATCACCTTATTATTGGTAATGCGgcccatcaccagcaccagcagcaccagcagcagcagcagtaccaccCGTCGCAGATGGGGCTGATGGCCGGAGACGGTCAGTGGGTCGATGGAGGAGCAGGAGGTGACGGGCTGATCGAGTCGACGACGGGAGACCGTAACGGGTCGTTGGGGTTTCCCCGGTGTTCGGGGGGCGCCGAGGTGTATCAGGGCGATACGGCGCCCCCCTTTTCACCTAACGTACCGGACCAGTACCAGCGTCCCAGTAGCAGCGATGGGACCACCATCCTGACGAACCTGaccgatcagcagcagcagcaccatcaccagcagcagcaacgcaacCAGCAATCGCAGCAGATGATGATCGCCCACAGCACGATGGGCAACAAGTACAAGGAGTACGTTgtgctccagcagcagcagcagcaggagcacgAGGTAGACCCGTACCAGGAGCAGCTGTTGTACCGCGTGGCAACACCTCAGCTGGGCGCCACGGCACCCTCCATTTCGCCCGCTCCCTGCTCCCCCAGCGTCACGTCAACGGATGTCGGGCAGACGCAGCTGCAGTCGGGCCAGGTCGAGTCGGCCAAGTCGGCCAACAAGGCGAACGGGCAGCCGGACGTGCACCGGTGCATCGAGTGTGACAAGGTGTTCAACAAAGTATGCTATCTgacacagcacaacaaaacgtTCCACTCCGGGGACAAACCGTACAAGTGTCATCGGTGCGGCAAACGCTTCCCGTGCAATCAGTCGTACGAGGAGCATCTGGCAAAGCATGGCGGCGAAAAACCGTTCAAGTGCGAACAGTGTCCGAAGCAGTTCAATCACAAGACGGATCTGCGCCGGCACATGTGTCTGCACAGTGGTTCCAAACCGTATGCCTGTGAGCAGTGCGGCAAGGGCTTTATCCGTAAGGATCACATGATCAAGCACTCGGAGACGCACCGGAAGAATGTGGCGGCTGGACAGGACCGGGGAGGCAACGGGCAGAAGCGGGCCGGTAAGGTGGGAGGCCTGAAGAAGGGAGGCAGCAAGAAGGACATCGTCGGACTGGTGGACGAATGA
Protein Sequence: MASNGGTLHGVPQSVSQQQQQQQHICSQCGLYFESASSLQVHHMHYHQHDSMNRWGSQQQPVVSTTLGTTAVATTTTTATTITTNGTAPSSTTPTSSDTENNNQPGSHTPTHATAGLKPVASPHTTIAAAADSSDNQPPTPQPTITEPGTPQSYGGGGTSPYHSQQQQQQQQQQQHQQQVSQHPHQLGLPTGSAGSEMHYPSYIHPGYDPGSYYSGGPGSGLDYGGGVLGAPLQPTDYKSGSSVVSSARYHPYGGGSSGSSNNGGGPDGSSPAVVSSNGGSAGMSPQVVSSSNGVTVAGSGSGSTTVTTVASTTSQSSQPAHSPPNGTGGSNIPPTPSPSPIQCEKCGMVCESDEALNEHEATIHSNVQSAQDQQQQRVDQVDLQGGGGNCYTYGAGGTGGTPVYPVKEEAPASDILDLDSQKMVGYGPAGDGGLLPPMNSLHPLQSMQRHPMMSWHDPHNFMGPPSLPPPHPSHGGGPDMKHSAAVAAAAAAAAYYHHPIKSEYSATPAIKSEYLGGGGGGHYGGTGSPIVKNEYSLPPTLPPPAVAPQPTNAQTMKQYADEMHDNQLATSPSDFPSTTTPQESGSQYRTFEPATSSLPGTAGPTKGTAWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISVHHHPGRDPNYANKGRRGGAGNGSGAGAGGGGSGGAGGGGAGSQIQQPIQQPVPPPDPPRSPEYGTGPGAQQYGSASAAGFSTAGNSPGHQHPGSVGQVVSSNQSPGFHHPYAGATSANGTTASSTSSAVPPNGVAGPSVQVSQPRGLQIYSNSSNSHSMAEQMEQATHTITTILTPTTHPLTSTVGIPDTLGTRISTSTTRTPTDTHTPPTMGMGSPVDHLQQQPQPPQQQQPPPQHIISSMEPYHHPHTQPHTMHTISNPLTISTSIPSFQTILPEAPSYHLIIGNAAHHQHQQHQQQQQYHPSQMGLMAGDGQWVDGGAGGDGLIESTTGDRNGSLGFPRCSGGAEVYQGDTAPPFSPNVPDQYQRPSSSDGTTILTNLTDQQQQHHHQQQQRNQQSQQMMIAHSTMGNKYKEYVVLQQQQQQEHEVDPYQEQLLYRVATPQLGATAPSISPAPCSPSVTSTDVGQTQLQSGQVESAKSANKANGQPDVHRCIECDKVFNKVCYLTQHNKTFHSGDKPYKCHRCGKRFPCNQSYEEHLAKHGGEKPFKCEQCPKQFNHKTDLRRHMCLHSGSKPYACEQCGKGFIRKDHMIKHSETHRKNVAAGQDRGGNGQKRAGKVGGLKKGGSKKDIVGLVDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101995;
90% Identity: iTF_00103992;
80% Identity: -