Basic Information

Insect: Anopheles stephensi
Gene Symbol: Prdm1
Assembly: GCA_013141755.1
Location: CM023249.1:14184319-14219761[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.6e-07 9.5e-06 25.6 0.8 1 23 838 860 838 860 0.99

2 5 8.4e-06 0.00049 20.2 5.1 1 23 866 888 866 888 0.98

3 5 1.8e-06 0.0001 22.3 4.3 1 23 894 916 894 916 0.98

4 5 0.00059 0.034 14.4 2.4 1 23 922 944 922 944 0.97

5 5 0.0001 0.0057 16.8 0.1 1 22 950 971 950 971 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.6e-07	9.5e-06	25.6	0.8	1	23	838	860	838	860	0.99
2	5	8.4e-06	0.00049	20.2	5.1	1	23	866	888	866	888	0.98
3	5	1.8e-06	0.0001	22.3	4.3	1	23	894	916	894	916	0.98
4	5	0.00059	0.034	14.4	2.4	1	23	922	944	922	944	0.97
5	5	0.0001	0.0057	16.8	0.1	1	22	950	971	950	971	0.96

Sequence Information

Coding Sequence: ATGTCTGGAGCGAATCCCCCTCGAAGCGTTACGCCAAACGCGCAGCAGGACTACGATGTTACGCGTATGCGAGAGGAAGACTTCGAGCGGCTGGCCGTCTACATCGTGCCGGACATGCCCTGCGAGAAGGGTGTACCGGGCCGGGCGGAGAAAACGTTACCCCGCAGCCTCACGCTCAAACCCTCCCTCGTCCTGTCGACGCCCACATCCACGACTGAAGGAGTGTGGAGCACAGGCGTCATCCCTCGGGGTACCAGATTTGGTCCGTTCGAGGGTGTCCGCACACCGAGCCATCCCAGTGACAAACAGCTATGGCGATACTTCTGGCGGGTGCAGGAACTACGACACGTTTCCTATGGGAATATCAAGATATTCAAGGACAGTGATTTCTACTACCTGGACGGGTCAGACACGGCCCAGTCCAACTGGATGCGGTACGTAGCGTCCGCGTACAGCTTCTCGGTGATGAATCTGGTCGCGTGCCAGCACCAGGAACACATCTACTTCTACACGATACGCGACATCATGCCGAACGAGGAGCTGATGGTGTGGTACTGTCGCGACTTTGCCAAGCGGCTCGGGTACGACATCGACCCGGAACGGGCGACCTACTCCATCTGTCGCGAGGAGGTCGTGAAGAAGACGTACAAACAGCCCGTCCCACCGGAGGTAGCGTACAACCACGTGAAGCACGTGATGGGCCTCTACCTGCCAGCGATGGTGCGCAGTACACCAACGCCGAGTCCTTCTCCGCCGGCCCCACCGACCAGTGGTCATGTTCCTTCCGCCAAGCATCACGCCCTCCACCAGACCGTTCTGAGAGAGCCTCGAAATGTTGGGCCGGTTGGTGGTACTGGTTCCGGTGCGGGTGACGAAACCCTGCGGGATCGATCCCCCATTCGCATTGTGATCCGAGAGCAGAGTCCACTGCTTCGGGAGAGCGTTAAGGAGGTGGACGCCGACTCACCAATCTCGCAGACGAAGGAAACCGCGTACGAACATCAGCTCACGCCGAACGATGGGTCGGTACGGTCGGACGAGGGCTACCACAGCAATGGGTACCATGAGGATGGGTTTACGCCACCGGAGGACTCGAGCGACAGCGAGAGCGAACACAACTACGTGCTGGACTGTTCGAAGAAGGCGATCGAGCCGAAGGAAACGAGTGTGGGTCAGCACAAGGTGAGCACAACGGAGCCGTGTGACAAGAACGAATATCGCAAGGTGAAGATGAAGATGCCGCTGAAGTACGAGttcaaaaacaacagcaagaaCTTCAAGGTAGAGCCGGAGCTGGAGATTGCAACCGAGCGGGAGGTTGAAGCGGTGGCAACGATCGGTGGCCCGGCGAGTACGGAACCGATTGTATCGGGAATGCGTGAGGTAACGCCTGCTACGAGTACCGTGATTGTGCTGGACACGACGCCCGAGACGGTTGTGGTGCCGCTGACGAAGAGCTACTACGAGGCAGAACCGACGTCAACGTCCCCGGCAACCTTCATCCGCTACACGCCACCAAGCTCGAGCTCGATCCTGGAAACCATCCTGACCGGCAGTACCCGTGCACCGTCGGTGGATGATCCGCACCGTCGGCAGCCGAACGCCACACCACCTCCAACGTCCCCGACCGAGATGGCCTACTCGTACAAGAAGTCGCAAAGGTACGGAACTGCCTGCAGTCCGGATTCGAGCTCCCAGAATCCGGCCCCGGAACCTACCGAGCCCACCTCCCGATCTCAGACTTCGCTCGAGCAGGAGCCCAAGGAGGCGGAACATGCGGAACTcgcgcaccatcatcatccgcaccatcaccacctcaaccatcatcacccgcatcatcatcatcatcatctgccgCCCCATCTGCATCATGGGCAGCAACCGCACCAGAGCAGCTACCACCACGGACACGATCGGCTACACGATCGTGAGGAAGCCGGTGCCTCTCCCTCGCCCTCCCCACTCGTCTACCCGGGCGAACATCATCATCTGCATCCTCACCATCACGGTGCGCAGCATCATGCGCCGCACCTGCACAGGACACACTCGCCCGTACCGTACGAATCGCCGGTACCGAGctacagcaccaccagcagcagtattTACTCGGCCTCGAACGGGTCGGCCAGTGTGATTAACAGCGCTTCCAGCTCCACCTACAGTCCGCCCCTGAACGGTGGACACTACGAGAGACTGACGACATCGTCGACGACCCCACTGCGCTCGGTATCGCCCGGTGTCCCGAACGGGGCGCCCGGCGGTGGCCCCGCTCAACCGGCCGGCTTTGTGCAGCTACAATCCAAAGGTCAGCTACCTCTTGGACATCCGCTCATGCAACCGCTCACCCCGCTCACGCACATGTCCCCCGGGCGTGTATCTCCACCGAGCAGTCTCAGTCCGGACGGGGGTTCGTACTCACGGAGCGGCAGTCCCATGAGCCCGGGCAGTCCGAATTCGCGCGGCTACCGGAGTCTACCGTATCCGTTGCGTAAGCGGGACGGGAAGATGCACTACGAGTGCAATGTGTGCAGCAAAACGTTTGGCCAGCTGTCGAACCTGAAGGTGCACCTGAGGACACATTCGGGCGAACGGCCGTTCAAGTGTAACGTGTGCACGAAATCCTTCACCCAGCTGGCGCACCTGCAGAAGCATCATCTGGTGCATACGGGCGAGAAGCCGCACCAGTGCGACATCTGCAAGAAGCGATTCTCGTCTACGTCCAACCTGAAGACGCATCtgcggctgcacagcggcCAGAAGCCGTACGCGTGTGATCTGTGCCCGCAGAAGTTTACCCAGTTCGTGCACCTGAAGCTGCACAAGCGGCTGCACACGAACGATCGGCCGTACGTGTGCCAGGGCTGTGATAAGAAGTACATCAGTGCGTCCGGGCTGCGAACGCACTGGAAGACGACCAGCTGCAAGCCGAACAATCTGGAGGAGGAGCTGGcgatggcggcggcggccacCTCCGAGTGTTTAGATAAGGATGGCCAACCGGATGGTGAAGGTGGGCGCGAATTCTACGAAATGTCTCACCTTCCCGCATCGCACCACGGCAGTCCGGGTGTGGTGCAGACGGCCACGTCCACCTCCGCCCAACCGCACCATCCTCACGCCGGTCTGGGTCACCATCACCATTCCGAGCAGGTCATACACAAGGTGTCGGCGGGCAAAATTCAGCAACACTCAAACGGTGTCGCCAGCAGTAACGGCGCgtcgagcaacaacaacagccccAACAGTACGAACCACAATCTACCGTCACCGCACCTGCACTACGGTGGCCATCTGGTGCAAACGACCACCAACGGGGGAGCGGGTGGTTCGAGCAGTTCCGCATCACAGCACGAACCCACCAGCCGGCCAAGTGTGATCGAGTCTAGCCAACCGATGGTGATCGAGTGTACGTAG
Protein Sequence: MSGANPPRSVTPNAQQDYDVTRMREEDFERLAVYIVPDMPCEKGVPGRAEKTLPRSLTLKPSLVLSTPTSTTEGVWSTGVIPRGTRFGPFEGVRTPSHPSDKQLWRYFWRVQELRHVSYGNIKIFKDSDFYYLDGSDTAQSNWMRYVASAYSFSVMNLVACQHQEHIYFYTIRDIMPNEELMVWYCRDFAKRLGYDIDPERATYSICREEVVKKTYKQPVPPEVAYNHVKHVMGLYLPAMVRSTPTPSPSPPAPPTSGHVPSAKHHALHQTVLREPRNVGPVGGTGSGAGDETLRDRSPIRIVIREQSPLLRESVKEVDADSPISQTKETAYEHQLTPNDGSVRSDEGYHSNGYHEDGFTPPEDSSDSESEHNYVLDCSKKAIEPKETSVGQHKVSTTEPCDKNEYRKVKMKMPLKYEFKNNSKNFKVEPELEIATEREVEAVATIGGPASTEPIVSGMREVTPATSTVIVLDTTPETVVVPLTKSYYEAEPTSTSPATFIRYTPPSSSSILETILTGSTRAPSVDDPHRRQPNATPPPTSPTEMAYSYKKSQRYGTACSPDSSSQNPAPEPTEPTSRSQTSLEQEPKEAEHAELAHHHHPHHHHLNHHHPHHHHHHLPPHLHHGQQPHQSSYHHGHDRLHDREEAGASPSPSPLVYPGEHHHLHPHHHGAQHHAPHLHRTHSPVPYESPVPSYSTTSSSIYSASNGSASVINSASSSTYSPPLNGGHYERLTTSSTTPLRSVSPGVPNGAPGGGPAQPAGFVQLQSKGQLPLGHPLMQPLTPLTHMSPGRVSPPSSLSPDGGSYSRSGSPMSPGSPNSRGYRSLPYPLRKRDGKMHYECNVCSKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDGQPDGEGGREFYEMSHLPASHHGSPGVVQTATSTSAQPHHPHAGLGHHHHSEQVIHKVSAGKIQQHSNGVASSNGASSNNNSPNSTNHNLPSPHLHYGGHLVQTTTNGGAGGSSSSASQHEPTSRPSVIESSQPMVIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103955;
90% Identity: iTF_00101945;
80% Identity: -