Aste005751.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- -
- Assembly
- GCA_013141755.1
- Location
- CM023249.1:2141033-2142620[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 2.7 1.6e+02 2.9 0.5 9 23 238 253 220 253 0.75 2 9 0.00057 0.033 14.4 0.1 2 23 261 282 260 282 0.97 3 9 0.014 0.83 10.0 0.7 1 23 288 308 288 308 0.89 4 9 0.00085 0.049 13.9 1.1 1 23 313 336 313 336 0.97 5 9 0.0033 0.19 12.0 0.8 2 23 342 363 341 363 0.94 6 9 0.00046 0.027 14.7 5.4 1 23 367 389 367 389 0.97 7 9 0.18 10 6.6 0.2 2 23 400 422 399 422 0.94 8 9 2e-05 0.0012 19.0 0.6 3 20 430 447 429 449 0.94 9 9 2e-05 0.0012 19.0 1.0 1 21 458 478 458 479 0.94
Sequence Information
- Coding Sequence
- ATGGAAGCCGCCACCCGCAAGTGCCGGACGTGTCTGTCCGTTGGCGAATCGGAATATTTGAGCATTTTTGCGGAGGAGAATCGGACGAAGAACATTGACACAATTATCGCCACACATCTTTGGTTTGAGGTAATTGCCACCGATGAAAGTCAGTGGATATGCCAGAGCTGTTGGTCAAAGCTGGAAGAGTTTCACGAATTCTACACCAACATCGAGCAGACGCACAAACACCAAACGCTTCTTGACGATGCCAATGTCGCCGCGAAAGAGCCTTCAGTATCCTCGCCCACCAGTTCCACCAGTCCTACGTACAATACAGAGTTTCTGGAGATAAAAGGCGAACCCTACGATCTAGAGGGGGCCAATGACGATGCCTTAAGTGTAGCGGACAGCAGGGTCAGCGATAAAATGCTGTCCGGTGGCGATATAAAGAGTGAAGAGTCGGACGAGtacgaggaggaggatgaggaggaCAGTGACTCGTCACTGCCACCGTACGAAGGAGGgacgaaaagaagaaaatccaCCCCCCGTGGGTCACGTGAGaccaaagcaagcaagcagccGACGGGTGAACGGTTGGCGAAGCGGAAGGCAGGTGGCCGCTTCCCTGCCGACCCGGAAGAGGACAGGAACATACTTCAGTTCTACCGGCGTATCGTTTGCGAGGTGTGCGACAACAAGCGGATGATGGTGGGCGAACCGCTGATCGAGTACGCGACCTGGGGCGAGCTGTTGCGGCACACGAAGGAAACGCATGGCCACTACAAGATCTTCGTGCAGTGTCCGGTGTGTGAGATGAAGCTGCGCACCAAGGTGACGCTGGTGCAGCACATGGATATGCACCAGAACCCGGAGAAGTACCGGTGCGAGGTGTGCGGCGAGGTGTTCCAGAACATGAAGGAACACATGCAGAACAAGCACGAGGAGCGCCAGTTTAGCTGCGATCTGTGCGGAAGCAAGTTCCCGTTCAAGAAGCGGCTCGTGGTGCACATGAAGAAGATGCACGCGGAAAAGAACGTCACGTGCGACCAGTGTCAGAAATCCTTCACGCGTTACACGATCGAAGACCATCGACGTTCGGTGCACATGGCCCGCTTTGTGTGCGAGCACTGTCCGAAAACGTTCAAAATTCGGTTCCGCTTGCACAAGCACATGCAGGAGCACGATAAGAGCTTGCGCATCTCCACGTCCGTGCCGTGTCCGACGTGTGGCCAGGTGATGGGCGACAAGTACATCCTCCGGCAGCACATCAAGCACATGCACAACGAGCAGCAGGCGGTCGATTGTGAGACGTGCGGCAAGACGTTCAAGAACTATCGCAACCTAAAGATACACCTGACGAACGTGTGCATGAAACCGATCCAGCTGCATCCGTGTGCGATCTGTGGCAAGCAGTTCCGGCACAAGAACAAGCTTAAAGATCACATGGCGTCCTGCACGCCGAATTGA
- Protein Sequence
- MEAATRKCRTCLSVGESEYLSIFAEENRTKNIDTIIATHLWFEVIATDESQWICQSCWSKLEEFHEFYTNIEQTHKHQTLLDDANVAAKEPSVSSPTSSTSPTYNTEFLEIKGEPYDLEGANDDALSVADSRVSDKMLSGGDIKSEESDEYEEEDEEDSDSSLPPYEGGTKRRKSTPRGSRETKASKQPTGERLAKRKAGGRFPADPEEDRNILQFYRRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKETHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPEKYRCEVCGEVFQNMKEHMQNKHEERQFSCDLCGSKFPFKKRLVVHMKKMHAEKNVTCDQCQKSFTRYTIEDHRRSVHMARFVCEHCPKTFKIRFRLHKHMQEHDKSLRISTSVPCPTCGQVMGDKYILRQHIKHMHNEQQAVDCETCGKTFKNYRNLKIHLTNVCMKPIQLHPCAICGKQFRHKNKLKDHMASCTPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103918;
- 90% Identity
- -
- 80% Identity
- -