Aste004019.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- ZFY
- Assembly
- GCA_013141755.1
- Location
- CM023249.1:76451057-76455775[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.19 11 6.5 2.4 1 23 143 165 143 166 0.92 2 15 0.0034 0.2 12.0 0.4 1 20 178 197 178 199 0.94 3 15 0.011 0.63 10.4 0.4 1 12 320 331 320 333 0.90 4 15 7.4 4.2e+02 1.5 0.1 1 21 348 368 348 373 0.89 5 15 6.6 3.8e+02 1.6 2.7 3 23 398 419 396 419 0.90 6 15 0.00031 0.018 15.3 2.4 1 21 432 452 432 453 0.94 7 15 0.11 6.1 7.3 1.7 1 23 509 533 509 533 0.90 8 15 0.013 0.73 10.2 0.0 1 20 557 576 557 578 0.93 9 15 0.044 2.5 8.5 0.1 2 23 587 608 586 608 0.96 10 15 0.00035 0.02 15.1 4.3 1 21 614 634 614 636 0.95 11 15 1.2e-06 6.7e-05 22.9 0.9 1 23 641 664 641 664 0.96 12 15 0.00026 0.015 15.5 1.1 2 23 670 691 669 691 0.96 13 15 0.1 6 7.3 0.5 1 23 697 722 697 722 0.94 14 15 0.00011 0.0063 16.7 2.6 1 23 728 750 728 750 0.98 15 15 6.6e-05 0.0038 17.4 0.0 1 21 756 776 756 777 0.96
Sequence Information
- Coding Sequence
- ATGAGTTCCAAACATTGCCGCATATGCTACAAACTAGATCAGGACGACCTCATCTCAGTGCGGCTGAAGCAGGATGGCATAAGCATCGAGGAGATGGTACTGACCATCACAAGCATTTCCGTGTCCGACGATCGTCGCCTACCACAAAACATTTGTCTCCAGTGTTTGGACCGATTGAAGGAAGCGGTCGAACTGCGCCAGCAATGCATCCGCACGCACGAACGGCTGTGTGCGGAGCTAGATTCGAACCATGGTATGCTTGTGGAAGAAAACGAACAAATTAAAGCAGAACCGGACGATGTGTCGTGCGACGATGCTTCGGTCGTTATCGAAAAGATCGAAATCGATGATGCGCTAAATCCGGAATCGGAACAGTCTGCCAACGACACGGACGAGGAGCACTATGAAGCAATCGAGGGGGAAGAGTTTGCGTGCTGTGGATGTGCCATGCGGTTCAGCACCCGTGATAAGCTAGACGAGCACGCCACGCTGCATCATCGGAATGGAAGCAGAAAGCTGCGTTCCGGTGCGTTTCACTGCCCAATGTGCTACCAATCGTTTCCAGATCGTACGATGCTCGATCGTCATCGAGAGGAGCTAAATCCCAGCCAGCGGGAAACGATTGCAGTCGAAGAAAACGAAATGACCGATGAAGAGGAGGACGAAGATCAAGCAAACGAAAGCGTGCGGGATGAAAGCGGCAGCGAAGAACAGACCAAACCTGATTCAACGGAACGGCTCCAGAGGGCAAGCATACAGAGGGCAATCTGTCGCTTGCCGGGGAACAGTTTGCTGGTAGTAGCAGAGGAACCACAAGGCTATCTGATTGTGGAGCTGCAGCCACaccggtgttgctgctgcgcgGAACTCTTCCAAACCGAGCAGGATCTTAACAAACATCTAGAGGAAAGGAAGCGTAGCAACGGCGTGAGCGGACCTACCGATCCGGAGCTGAAATACACCTGCGAGTACTGTGGCAAACGGTTTGCGTACTGGTTGGTGTACCTGTGCCACAAGCGCGTCCGGGACCAGCGCCAGTTTTACATGTGCGGGCTGTGCGATGCGCTGCTCGACTCGAAAAAGCGCATGATATCGCACATGCTGATGTCGGACGAGCATGCCGATCATTTCCAGCTTGCCCGGGCGAATGTCGCCGATCGGTACGAAGCGATTGAATGGCCGGGAGtgcgttgctgttgctgcaagAAGTATTTCGCGCAAGAAGCGGAACGGATGGAGCACATGGCTCGAGAGCATGGTGTATCGAAGACAGCCTTTGCCGCGGATCACCCGCACAGTTGCAGGGTTTGTGGCCGTCAGTTTAGAACCGTACGGCACCTGGAACGTCATCAACAGTACAGCGAGGACGTTAAGGAGTACTACTGCAAGCTGTGTGACTTTCAGACGCTCAATCCTCGACGCATGGAGCTTCACCTGTACAGTGGCATTCATCGCGATGAGCTACCGGCCACGGTTGAACTGAAATCGCTTCAGAATAACCAACTGAAAGCATCCCACTTACGGTACTGTTGTTTCGAAGACTGCCACCAACCGTTCGCCGATGGGCCGGCCCTTCGGCGGCACGTACACGAGGCACACGAAGCAGCGCTCACGGCGAACCGGCAGCAGACGAGCAAATTAAGCCAACTGCTACAGTCCGGAACGTACCACGCGTGTGACGATTGTGGCGTACTGTTCAGGAACCTTCCCGCCCTACAAGCGCACCGTGTTCGGCGACCGGCCCGCCAGCAAGCGCTCGTGTGCGCGATTTGCGGTGTATCGAAGAGCTCCCGGACGTTGCTGCGCATCCACGAACGTTCGCACACCGGCGAACGCCCGTATCGGTGCAACGATTGCGACAAAACGTTCTTCAGCAATCAGGCGCTACTGTCCCACCGCCGGTGCCATCTGACCGGCACGTACAAATGCGACACCTGCGGGAGTGTGTTCAATCGGAAGGAAAATCTTAACCGGCACATTCTGCTCAAGCACGGCATAGCCACCATCCCGTGTGCCGATTGTCCGAAGCTGTTTAAAACGATGCACACGCTAAACCGGCACCGGCTAATGCACACGGGCGAGAAGCGGTACCGGTGCCGGACGGCATCCTGCGACAAACGGTACGTCAACGAGGTCGATCGGCGCCGGCACGAGATGTCGGTGCACACGCTCGAACGGCCGCACCGGTGTGCGCACTGTGGGGCCGGGTTCATCCGGAGGCGGCAGCTGACGGTACACGAGCGGCGGCACACGGGCGTGAAACCGTACGTGTGTCCGGTGTGCGGGAAGGATTTCGTGGATGTGGGCCCGCTGAGGAGTCATATGCGAAACGTTTGCAAACGGACGGTGGATGGGGAGATGGGGGAGGGAAGCGACTCGTGA
- Protein Sequence
- MSSKHCRICYKLDQDDLISVRLKQDGISIEEMVLTITSISVSDDRRLPQNICLQCLDRLKEAVELRQQCIRTHERLCAELDSNHGMLVEENEQIKAEPDDVSCDDASVVIEKIEIDDALNPESEQSANDTDEEHYEAIEGEEFACCGCAMRFSTRDKLDEHATLHHRNGSRKLRSGAFHCPMCYQSFPDRTMLDRHREELNPSQRETIAVEENEMTDEEEDEDQANESVRDESGSEEQTKPDSTERLQRASIQRAICRLPGNSLLVVAEEPQGYLIVELQPHRCCCCAELFQTEQDLNKHLEERKRSNGVSGPTDPELKYTCEYCGKRFAYWLVYLCHKRVRDQRQFYMCGLCDALLDSKKRMISHMLMSDEHADHFQLARANVADRYEAIEWPGVRCCCCKKYFAQEAERMEHMAREHGVSKTAFAADHPHSCRVCGRQFRTVRHLERHQQYSEDVKEYYCKLCDFQTLNPRRMELHLYSGIHRDELPATVELKSLQNNQLKASHLRYCCFEDCHQPFADGPALRRHVHEAHEAALTANRQQTSKLSQLLQSGTYHACDDCGVLFRNLPALQAHRVRRPARQQALVCAICGVSKSSRTLLRIHERSHTGERPYRCNDCDKTFFSNQALLSHRRCHLTGTYKCDTCGSVFNRKENLNRHILLKHGIATIPCADCPKLFKTMHTLNRHRLMHTGEKRYRCRTASCDKRYVNEVDRRRHEMSVHTLERPHRCAHCGAGFIRRRQLTVHERRHTGVKPYVCPVCGKDFVDVGPLRSHMRNVCKRTVDGEMGEGSDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -